Developmental regulation of RNA processing by Rbfox proteins

Genome Sequencing of Autism-Affected Families Reveals Disruption of Putative Noncoding Regulatory DNA

(2016) Tychele N. Turner et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR

(2016) Andrey Damianov et al.   CELL

Repression of Pumilio Protein Expression by Rbfox1 Promotes Germ Cell Differentiation

(2016) Arnaldo Carreira-Rosario et al.   DEVELOPMENTAL CELL

RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes

(2016) Chaoliang Wei et al.   MOLECULAR CELL

Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes

(2016) Ji-Ann Lee et al.   NEURON

Rbfox proteins regulate microRNA biogenesis by sequence-specific binding to their precursors and target downstream Dicer

(2016) Yu Chen et al.   NUCLEIC ACIDS RESEARCH

Rbfox2 function in RNA metabolism is impaired in hypoplastic left heart syndrome patient hearts

(2016) Sunil K. Verma et al.   Scientific Reports

Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes

(2016) Curtis A. Nutter et al.   Cell Reports

MiR-980 Is a Memory Suppressor MicroRNA that Regulates the Autism-Susceptibility Gene A2bp1

(2016) Tugba Guven-Ozkan et al.   Cell Reports

Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson’s Disease Patients

(2016) Lin Lin et al.   Cell Reports

Essential role of the nuclear isoform of RBFOX1, a candidate gene for autism spectrum disorders, in the brain development

(2016) Nanako Hamada et al.   Scientific Reports

Extending the phenotypic spectrum ofRBFOX1deletions: Sporadic focal epilepsy

(2015) Dennis Lal et al.   EPILEPSIA

The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure and function

(2015) Simona Pedrotti et al.   HUMAN MOLECULAR GENETICS

RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure

(2015) Chen Gao et al.   JOURNAL OF CLINICAL INVESTIGATION

Copy Number Variations inCTNNA3andRBFOX1Associate with Pediatric Food Allergy

(2015) Jin Li et al.   JOURNAL OF IMMUNOLOGY

Structural imprints in vivo decode RNA regulatory mechanisms

(2015) Robert C. Spitale et al.   NATURE

Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators

(2015) Qinghong Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies

(2015) J. Homsy et al.   SCIENCE

Repression of the Central Splicing Regulator RBFox2 Is Functionally Linked to Pressure Overload-Induced Heart Failure

(2015) Chaoliang Wei et al.   Cell Reports

Role of the cytoplasmic isoform of RBFOX1/A2BP1 in establishing the architecture of the developing cerebral cortex

(2015) Nanako Hamada et al.   Molecular Autism

Targeted massively parallel sequencing of autism spectrum disorder-associated genes in a case control cohort reveals rare loss-of-function risk variants

(2015) Anthony J. Griswold et al.   Molecular Autism

Copy number variations and susceptibility to lateral temporal epilepsy: A study of 21 pedigrees

(2014) Manuela Fanciulli et al.   EPILEPSIA

Rbfox2 controls autoregulation in RNA-binding protein networks

(2014) M. Jangi et al.   GENES & DEVELOPMENT

RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts

(2014) Yang I. Li et al.   GENOME RESEARCH

Rbfox2-Coordinated Alternative Splicing of Mef2d and Rock2 Controls Myoblast Fusion during Myogenesis

(2014) Ravi K. Singh et al.   MOLECULAR CELL

RNA Bind-n-Seq: Quantitative Assessment of the Sequence and Structural Binding Specificity of RNA Binding Proteins

(2014) Nicole Lambert et al.   MOLECULAR CELL

Rbfox3 controls the biogenesis of a subset of microRNAs

(2014) Kee K Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1

(2014) Roscoe Klinck et al.   PLoS One

The human splicing code reveals new insights into the genetic determinants of disease

(2014) H. Y. Xiong et al.   SCIENCE

HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism

(2014) Sebastien M. Weyn-Vanhentenryck et al.   Cell Reports

Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin

(2013) P. Mallinjoud et al.   GENOME RESEARCH

Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

(2013) Dwight Stambolian et al.   HUMAN MOLECULAR GENETICS

A compendium of RNA-binding motifs for decoding gene regulation

(2013) Debashish Ray et al.   NATURE

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

(2013) Michael T Lovci et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Correction: RBFOX1 and RBFOX3 Mutations in Rolandic Epilepsy

(2013) Dennis Lal et al.   PLoS One

MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation

(2013) Julian P. Venables et al.   Nature Communications

Intragenic deletion of RBFOX1 associated with neurodevelopmental/neuropsychiatric disorders and possibly other clinical presentations

(2013) Wei-Wei Zhao   Molecular Cytogenetics

Rbfox1 Downregulation and Altered Calpain 3 Splicing by FRG1 in a Mouse Model of Facioscapulohumeral Muscular Dystrophy (FSHD)

(2013) Mariaelena Pistoni et al.   PLoS Genetics

Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia

(2013) Amy K. Kiefer et al.   PLoS Genetics

Rare inheritedA2BP1deletion in a proband with autism and developmental hemiparesis

(2012) L.K. Davis et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function

(2012) L. T. Gehman et al.   GENES & DEVELOPMENT

Genome-Wide Determination of a Broad ESRP-Regulated Posttranscriptional Network by High-Throughput Sequencing

(2012) K. A. Dittmar et al.   MOLECULAR AND CELLULAR BIOLOGY

RBFOX2 Is an Important Regulator of Mesenchymal Tissue-Specific Splicing in both Normal and Cancer Tissues

(2012) J. P. Venables et al.   MOLECULAR AND CELLULAR BIOLOGY

Long Noncoding RNAs with snoRNA Ends

(2012) Qing-Fei Yin et al.   MOLECULAR CELL

Muscle-Specific Splicing Factors ASD-2 and SUP-12 Cooperatively Switch Alternative Pre-mRNA Processing Patterns of the ADF/Cofilin Gene in Caenorhabditis elegans

(2012) Genta Ohno et al.   PLoS Genetics

Pontocerebellar hypoplasia in association with de novo 19p13.11p13.12 microdeletion

(2011) Natalie M. Gallant et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions

(2011) Thomas L. Gallagher et al.   DEVELOPMENTAL BIOLOGY

Complex Congenital Heart Defects in Association with Maternal Diabetes and Partial Deletion of theA2BP1Gene

(2011) Seema Lale et al.   Fetal and Pediatric Pathology

RBFOX2 Promotes Protein 4.1R Exon 16 Selection via U1 snRNP Recruitment

(2011) S.-C. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

(2011) Lauren T Gehman et al.   NATURE GENETICS

NeuN/Rbfox3 Nuclear and Cytoplasmic Isoforms Differentially Regulate Alternative Splicing and Nonsense-Mediated Decay of Rbfox2

(2011) B. Kate Dredge et al.   PLoS One

Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2

(2011) S. Sun et al.   RNA

Understanding splicing regulation through RNA splicing maps

(2011) Joshua T. Witten et al.   TRENDS IN GENETICS

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

(2011) Irina M. Shapiro et al.   PLoS Genetics

An ESRP-regulated splicing programme is abrogated during the epithelial–mesenchymal transition

(2010) Claude C Warzecha et al.   EMBO JOURNAL

Exon-Level Microarray Analyses Identify Alternative Splicing Programs in Breast Cancer

(2010) A. Lapuk et al.   MOLECULAR CANCER RESEARCH

Deciphering the splicing code

(2010) Yoseph Barash et al.   NATURE

Fox-3 and PSF interact to activate neural cell-specific alternative splicing

(2010) Kee K. Kim et al.   NUCLEIC ACIDS RESEARCH

Global regulation of alternative splicing during myogenic differentiation

(2010) Christopher S. Bland et al.   NUCLEIC ACIDS RESEARCH

Integrative Modeling Defines the Nova Splicing-Regulatory Network and Its Combinatorial Controls

(2010) C. Zhang et al.   SCIENCE

Fox-1 family of RNA-binding proteins

(2009) Hidehito Kuroyanagi   CELLULAR AND MOLECULAR LIFE SCIENCES

An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons

(2009) J.-A. Lee et al.   GENES & DEVELOPMENT

Identification of Neuronal Nuclei (NeuN) as Fox-3, a New Member of the Fox-1 Gene Family of Splicing Factors

(2009) Kee K. Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer-associated regulation of alternative splicing

(2009) Julian P Venables et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

(2009) Gene W Yeo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Autoregulation of Fox protein expression to produce dominant negative splicing factors

(2009) A. Damianov et al.   RNA

Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2

(2008) C. Zhang et al.   GENES & DEVELOPMENT

hnRNP H and hnRNP F Complex with Fox2 To Silence Fibroblast Growth Factor Receptor 2 Exon IIIc

(2008) D. M. Mauger et al.   MOLECULAR AND CELLULAR BIOLOGY

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

(2008) A. Kalsotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA