Immunomodulatory Protein Hydrolysates and Their Application

Immunomodulatory and anticancer protein hydrolysates (peptides) from food proteins: A review

(2018) Meram Chalamaiah et al.   FOOD CHEMISTRY

Immunomodulating protein aggregates in soy and whey hydrolysates and their resistance to digestion in an in vitro infant gastrointestinal model: new insights in the mechanism of immunomodulatory hydrolysates

(2018) Mensiena B. G. Kiewiet et al.   Food & Function

A Long-Term Follow-Up of the Efficacy of Nature-Based Therapy for Adults Suffering from Stress-Related Illnesses on Levels of Healthcare Consumption and Sick-Leave Absence: A Randomized Controlled Trial

(2018) Sus Corazon et al.   International Journal of Environmental Research and Public Health

Dietary Fiber Pectin Directly Blocks Toll-Like Receptor 2–1 and Prevents Doxorubicin-Induced Ileitis

(2018) Neha M. Sahasrabudhe et al.   Frontiers in Immunology

Anti-inflammatory effects of egg yolk livetins (α, β, and γ-livetin) fraction and its enzymatic hydrolysates in lipopolysaccharide-induced RAW 264.7 macrophages

(2017) Chalamaiah Meram et al.   FOOD RESEARCH INTERNATIONAL

Immune-enhancement effects of tuna cooking drip and its enzymatic hydrolysate in Balb/c mice

(2017) Min-Ji Kim et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Partially hydrolyzed whey proteins prevent clinical symptoms in a cow's milk allergy mouse model and enhance regulatory T and B cell frequencies

(2017) Mensiena B. Gea Kiewiet et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A novel whey tetrapeptide IPAV reduces interleukin-8 production induced by TNF-α in human intestinal Caco-2 cells

(2017) Machi Oyama et al.   Journal of Functional Foods

Toll-like receptor mediated activation is possibly involved in immunoregulating properties of cow's milk hydrolysates

(2017) M. B. Gea Kiewiet et al.   PLoS One

Readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutritional supplement: A randomized clinical trial

(2016) Nicolaas E. Deutz et al.   CLINICAL NUTRITION

Bioprocess challenges to the isolation and purification of bioactive peptides

(2016) Dominic Agyei et al.   FOOD AND BIOPRODUCTS PROCESSING

Bioactive protein hydrolysates in the functional food ingredient industry: Overcoming current challenges

(2016) Tomas Lafarga et al.   FOOD REVIEWS INTERNATIONAL

Exogenous opioid peptides derived from food proteins and their possible uses as dietary supplements: A critical review

(2016) Azzurra Stefanucci et al.   FOOD REVIEWS INTERNATIONAL

Enzymatic preparation of immunomodulatory hydrolysates from defatted wheat germ (Triticum Vulgare) globulin

(2016) Wenjia Wu et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Potential Applications of Food Derived Bioactive Peptides in Management of Health

(2016) Anusha Dhaval et al.   International Journal of Peptide Research and Therapeutics

Toll-like receptors in the pathogenesis of chemotherapy-induced gastrointestinal toxicity

(2016) Elke Cario   Current Opinion in Supportive and Palliative Care

Mesenteric IL-10-producing CD5+ regulatory B cells suppress cow’s milk casein-induced allergic responses in mice

(2016) A-Ram Kim et al.   Scientific Reports

Dietary bioactive peptides: Human studies

(2015) Dominique Bouglé et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Mucositis

(2015) Alessandro Villa et al.   CURRENT OPINION IN ONCOLOGY

Regulatory B Cells: Origin, Phenotype, and Function

(2015) Elizabeth C. Rosser et al.   IMMUNITY

Effect of Whey Protein Hydrolysate on Performance and Recovery of Top-Class Orienteering Runners

(2015) Mette Hansen et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

The impact of dietary fibers on dendritic cell responses in vitro is dependent on the differential effects of the fibers on intestinal epithelial cells

(2015) Miriam Bermudez-Brito et al.   MOLECULAR NUTRITION & FOOD RESEARCH

IL-6 as a keystone cytokine in health and disease

(2015) Christopher A Hunter et al.   NATURE IMMUNOLOGY

Chemical composition and immunomodulatory effects of enzymatic protein hydrolysates from common carp (Cyprinus carpio) egg

(2015) M. Chalamaiah et al.   NUTRITION

Immunomodulating properties of protein hydrolysates for application in cow's milk allergy

(2015) M. B. G. Kiewiet et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Prenatal maternal stress predicts reductions in CD4+ lymphocytes, increases in innate-derived cytokines, and a Th2 shift in adolescents: Project Ice Storm

(2015) Franz Veru et al.   PHYSIOLOGY & BEHAVIOR

The anti-inflammatory potential of a moderately hydrolysed casein and its 5 kDa fraction in in vitro and ex vivo models of the gastrointestinal tract

(2015) A. Mukhopadhya et al.   Food & Function

Bioactive peptides and protein hydrolysates: research trends and challenges for application as nutraceuticals and functional food ingredients

(2015) Eunice CY Li-Chan   Current Opinion in Food Science

Comparative Evaluation of Opioid-Induced Changes in Immune Reactivity of CBA Mice

(2014) M. A. Cheido et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Effects of stress on immune function: the good, the bad, and the beautiful

(2014) Firdaus S. Dhabhar   IMMUNOLOGIC RESEARCH

Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009

(2014) Dana Dabelea et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Amino acid supplementation and impact on immune function in the context of exercise

(2014) Vinicius Fernandes Cruzat et al.   Journal of the International Society of Sports Nutrition

Enzymatic hydrolysis optimization ofPaphia undulataand lymphocyte proliferation activity of the isolated peptide fractions

(2014) Xiao Qing He et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Toll-like receptor 6 stimulation promotes T-helper 1 and 17 responses in gastrointestinal-associated lymphoid tissue and modulates murine experimental colitis

(2014) M E Morgan et al.   Mucosal Immunology

Validation of bovine glycomacropeptide as an intestinal anti-inflammatory nutraceutical in the lymphocyte-transfer model of colitis

(2013) Mercedes Ortega-González et al.   BRITISH JOURNAL OF NUTRITION

Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study

(2013) Bingna Cai et al.   CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY

Mucosal Immunology of Food Allergy

(2013) M. Cecilia Berin et al.   CURRENT BIOLOGY

Innate receptors for adaptive immunity

(2013) Marie-Cécile Michallet et al.   CURRENT OPINION IN MICROBIOLOGY

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo

(2013) Katherine A. Smith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunomodulatory activities of whey β-lactoglobulin tryptic-digested fractions

(2013) Javier Rodríguez-Carrio et al.   INTERNATIONAL DAIRY JOURNAL

Immunomodulatory and hypoallergenic properties of milk protein hydrolysates in ICR mice

(2013) D.D. Pan et al.   JOURNAL OF DAIRY SCIENCE

Mu opioid receptor agonist-selective regulation of interleukin-4 in T lymphocytes

(2013) Christine Börner et al.   JOURNAL OF NEUROIMMUNOLOGY

Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes

(2013) S. Caron et al.   MOLECULAR AND CELLULAR BIOLOGY

The immunopotentiating effects of shark-derived protein hydrolysate

(2013) Jean-François Mallet et al.   NUTRITION

Oral treatment with β-lactoglobulin peptides prevents clinical symptoms in a mouse model for cow's milk allergy

(2013) Laura A. P. M. Meulenbroek et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Endocytic Mechanism of Internalization of Dietary Peptide Lunasin into Macrophages in Inflammatory Condition Associated with Cardiovascular Disease

(2013) Anthony Cam et al.   PLoS One

The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation

(2012) Jennifer Kovacs-Nolan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Potential mechanisms explaining why hydrolyzed casein-based diets outclass single amino acid-based diets in the prevention of autoimmune diabetes in diabetes-prone BB rats

(2012) J. T. J. Visser et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

β-Casein hydrolysate generated by the cell envelope-associated proteinase of Lactobacillus delbrueckii ssp. lactis CRL 581 protects against trinitrobenzene sulfonic acid-induced colitis in mice

(2012) M.B. Espeche Turbay et al.   JOURNAL OF DAIRY SCIENCE

A novel bioactive peptide from yoghurts modulates expression of the gel-forming MUC2 mucin as well as population of goblet cells and Paneth cells along the small intestine

(2012) Pascale Plaisancié et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Stress-induced redistribution of immune cells—From barracks to boulevards to battlefields: A tale of three hormones – Curt Richter Award Winner

(2012) Firdaus S. Dhabhar et al.   PSYCHONEUROENDOCRINOLOGY

Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds

(2011) Fatou Ndiaye et al.   EUROPEAN JOURNAL OF NUTRITION

Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways

(2011) Agnieszka Kaczmarek et al.   JOURNAL OF PATHOLOGY

Effects of soybean peptide on immune function, brain function, and neurochemistry in healthy volunteers

(2011) Dilshat Yimit et al.   NUTRITION

Oral tolerance induction by partially hydrolyzed whey protein in mice is associated with enhanced numbers of Foxp3+ regulatory T-cells in the mesenteric lymph nodes

(2011) Betty C. A. M. van Esch et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

(2010) H. Okada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat

(2010) J. T. J. Visser et al.   DIABETOLOGIA

Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial

(2010) Kerry S Kuehl et al.   Journal of the International Society of Sports Nutrition

The (193-209) 17-residues peptide of bovine β-casein is transported through Caco-2 monolayer

(2010) Daniela Regazzo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Clinical practice. Diagnosis and treatment of cow’s milk allergy

(2009) C. M. Frank Kneepkens et al.   EUROPEAN JOURNAL OF PEDIATRICS

Soybean protein fraction digested with neutral protease preparation, “Peptidase R”, produced by Rhizopus oryzae, stimulates innate cellular immune system in mouse

(2009) Shintaro Egusa et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Presence of Lunasin in Plasma of Men after Soy Protein Consumption

(2009) Vermont P. Dia et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Delayed-onset muscle injury and its modification by wheat gluten hydrolysate

(2009) Natsue Koikawa et al.   NUTRITION

Influence of tart cherry juice on indices of recovery following marathon running

(2009) G. Howatson et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Therapeutic potential of hen egg white peptides for the treatment of intestinal inflammation

(2009) Maggie Lee et al.   Journal of Functional Foods

Enzymatic preparation of immunomodulating hydrolysates from soy proteins

(2008) XiangZhen Kong et al.   BIORESOURCE TECHNOLOGY

Bovine glycomacropeptide ameliorates experimental rat ileitis by mechanisms involving downregulation of interleukin 17

(2008) P Requena et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of mesenteric lymph nodes and aging in secretory IgA production in mice

(2008) A.F. Santiago et al.   CELLULAR IMMUNOLOGY

Immunomodulatory effects of marine oligopeptide preparation from Chum Salmon (Oncorhynchus keta) in mice

(2008) Ruiyue Yang et al.   FOOD CHEMISTRY

Adaptive Foxp3+ Regulatory T Cell-Dependent and -Independent Control of Allergic Inflammation

(2008) Maria A. Curotto de Lafaille et al.   IMMUNITY

Protein Hydrolysates Induce CCK Release from Enteroendocrine Cells and Act as Partial Agonists of the CCK1Receptor

(2008) Martin Foltz et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Supplementation with a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise

(2008) Jonathan D. Buckley et al.   JOURNAL OF SCIENCE AND MEDICINE IN SPORT

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation

(2007) Guillaume Dalmasso et al.   GASTROENTEROLOGY