The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)
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Title
The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)
Authors
Keywords
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Journal
PHYSIOLOGICAL REVIEWS
Volume 98, Issue 1, Pages 505-553
Publisher
American Physiological Society
Online
2017-12-25
DOI
10.1152/physrev.00023.2016
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- Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury
- (2013) Qiuhua Chen et al. JOURNAL OF SURGICAL RESEARCH
- The components of the angiotensin-(1-7) system are differentially expressed during follicular wave in cattle
- (2013) Marcos Henrique Barreta et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- The nonpeptide ANG-(1–7) mimic AVE 0991 attenuates cardiac remodeling and improves baroreflex sensitivity in renovascular hypertensive rats
- (2013) Thelma Maria Bedeti Cunha et al. LIFE SCIENCES
- Angiotensin (1-7) contributes to nitric oxide tonic inhibition of vasopressin release during hemorrhagic shock in acute ethanol intoxicated rodents
- (2013) Annie M. Whitaker et al. LIFE SCIENCES
- Protective effects of angiotensin-(1-7) administrated with an angiotensin-receptor blocker in a rat model of chronic kidney disease
- (2013) Chengyan Xu et al. NEPHROLOGY
- The expression of angiotensin-converting enzyme 2–angiotensin-(1–7)–Mas receptor axis are upregulated after acute cerebral ischemic stroke in rats
- (2013) Jie Lu et al. NEUROPEPTIDES
- Anti-inflammatory effects of angiotensin-(1-7) in ischemic stroke
- (2013) Robert W. Regenhardt et al. NEUROPHARMACOLOGY
- Oral Angiotensin-(1–7) prevented obesity and hepatic inflammation by inhibition of resistin/TLR4/MAPK/NF-κB in rats fed with high-fat diet
- (2013) Sérgio Henrique Sousa Santos et al. PEPTIDES
- Angiotensin-(1-7) inhibits vascular calcification in rats
- (2013) Yu-Bin Sui et al. PEPTIDES
- An orally active angiotensin-(1–7) inclusion compound and exercise training produce similar cardiovascular effects in spontaneously hypertensive rats
- (2013) Mariane Bertagnolli et al. PEPTIDES
- The Novel Mas agonist, CGEN-856S, Attenuates Isoproterenol-Induced Cardiac Remodeling and Myocardial Infarction Injury in Rats
- (2013) Sílvia Q. Savergnini et al. PLoS One
- PD123319 Augments Angiotensin II-Induced Abdominal Aortic Aneurysms through an AT2 Receptor-Independent Mechanism
- (2013) Alan Daugherty et al. PLoS One
- Beneficial Effects of the Activation of the Angiotensin-(1–7) Mas Receptor in a Murine Model of Adriamycin-Induced Nephropathy
- (2013) Kátia Daniela Silveira et al. PLoS One
- The Effects of Angiotensin II and Angiotensin-(1–7) in the Rostral Ventrolateral Medulla of Rats on Stress-Induced Hypertension
- (2013) Dongshu Du et al. PLoS One
- Utero-placental expression of angiotensin-(1–7) and ACE2 in the pregnant guinea-pig
- (2013) Gloria Valdés et al. Reproductive Biology and Endocrinology
- Angiotensin-(1–7) reduces the perfusion pressure response to angiotensin II and methoxamine via an endothelial nitric oxide-mediated pathway in cirrhotic rat liver
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- Chronic infusion of angiotensin-(1-7) into the lateral ventricle of the brain attenuates hypertension in DOCA-salt rats
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- Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system
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- Dietary sodium intake modulates renal excretory responses to intrarenal angiotensin (1–7) administration in anesthetized rats
- (2012) Julie O'Neill et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Angiotensin Peptides and Nitric Oxide in Cardiovascular Disease
- (2012) Kaushik P. Patel et al. ANTIOXIDANTS & REDOX SIGNALING
- Angiotensin Converting Enzyme 2 Contributes to Sex Differences in the Development of Obesity Hypertension in C57BL/6 Mice
- (2012) Manisha Gupte et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Angiotensin-(1–7) regulates Angiotensin II-induced VCAM-1 expression on vascular endothelial cells
- (2012) Feng Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Angiotensin-(1–7) upregulates central nitric oxide synthase in spontaneously hypertensive rats
- (2012) Bruno D. Cerrato et al. BRAIN RESEARCH
- Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways
- (2012) Ahmed Z El-Hashim et al. BRITISH JOURNAL OF PHARMACOLOGY
- Suppressing inflammation by inhibiting the NF-κB pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia
- (2012) Teng Jiang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Immunohistochemical localization of the angiotensin-(1–7) receptor Mas in the murine forebrain
- (2012) M. Freund et al. CELL AND TISSUE RESEARCH
- Angiotensin-(1–7) Via the Mas Receptor Alleviates the Diabetes-Induced Decrease in GFAP and GAP-43 Immunoreactivity with Concomitant Reduction in the COX-2 in Hippocampal Formation: An Immunohistochemical Study
- (2012) Waleed M. Renno et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Angiotensin-(1–7) in kidney disease: a review of the controversies
- (2012) Danielle Zimmerman et al. CLINICAL SCIENCE
- Angiotensin 1-7 as Means to Prevent the Metabolic Syndrome: Lessons From the Fructose-Fed Rat Model
- (2012) Y. Marcus et al. DIABETES
- Evidence that angiotensin-(1-7) is an intermediate of gonadotrophin-induced oocyte maturation in the rat preovulatory follicle
- (2012) Kinulpe Honorato-Sampaio et al. EXPERIMENTAL PHYSIOLOGY
- AVE 0991, a non-peptide Mas-receptor agonist, facilitates penile erection
- (2012) Andrey C. da Costa Gonçalves et al. EXPERIMENTAL PHYSIOLOGY
- Murine Recombinant Angiotensin-Converting Enzyme 2
- (2012) Minghao Ye et al. HYPERTENSION
- Central Angiotensin-(1–7) Improves Vagal Function Independent of Blood Pressure in Hypertensive (mRen2)27 Rats
- (2012) Manisha Nautiyal et al. HYPERTENSION
- Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice
- (2012) Vaibhav B. Patel et al. HYPERTENSION
- Functional Cross-Talk Between Aldosterone and Angiotensin-(1-7) in Ventricular Myocytes
- (2012) Pedro W. Machado de Almeida et al. HYPERTENSION
- Angiotensin II-induced pro-fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells
- (2012) María Gabriela Morales et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Angiotensin-(1–7) central administration induces anxiolytic-like effects in elevated plus maze and decreased oxidative stress in the amygdala
- (2012) Walther Bild et al. JOURNAL OF AFFECTIVE DISORDERS
- In Vivo Expression of Angiotensin-(1-7) Lowers Blood Pressure and Improves Baroreflex Function in Transgenic (mRen2)27 Rats
- (2012) Maria A. Garcia-Espinosa et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Tissue specific localization of angiotensin-(1–7) and its receptor Mas in the uterus of ovariectomized rats
- (2012) João Vaz-Silva et al. JOURNAL OF MOLECULAR HISTOLOGY
- Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury
- (2012) G. J. Rey-Parra et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Time-Resolved Quantitative Phosphoproteomics: New Insights into Angiotensin-(1–7) Signaling Networks in Human Endothelial Cells
- (2012) Thiago Verano-Braga et al. JOURNAL OF PROTEOME RESEARCH
- Possible mechanism of the cardio-renal protective effects of AVE-0991, a non-peptide Mas-receptor agonist, in diabetic rats
- (2012) Kulwinder Singh et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- Antenatal betamethasone exposure alters renal responses to angiotensin-(1–7) in uninephrectomized adult male sheep
- (2012) Jianli Bi et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice
- (2012) Renisha Nadarajah et al. KIDNEY INTERNATIONAL
- Angiotensin-(1–7) attenuates high glucose-induced proximal tubular epithelial-to-mesenchymal transition via inhibiting ERK1/2 and p38 phosphorylation
- (2012) Li Zhou et al. LIFE SCIENCES
- ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
- (2012) Tatsuo Hashimoto et al. NATURE
- Superoxide anions modulate the effects of angiotensin-(1–7) in the rostral ventrolateral medulla on cardiac sympathetic afferent reflex and sympathetic activity in rats
- (2012) P. Li et al. NEUROSCIENCE
- Angiotensin-(1-7) inhibits neuronal activity of dorsolateral periaqueductal gray via a nitric oxide pathway
- (2012) Jihong Xing et al. NEUROSCIENCE LETTERS
- Role of angiotensin-converting enzyme (ACE and ACE2) imbalance on tourniquet-induced remote kidney injury in a mouse hindlimb ischemia–reperfusion model
- (2012) Xiu-hong Yang et al. PEPTIDES
- Captopril intake decreases body weight gain via angiotensin-(1–7)
- (2012) Young-Bin Oh et al. PEPTIDES
- Exercise induces renin–angiotensin system unbalance and high collagen expression in the heart of Mas-deficient mice
- (2012) Gislaine G. Guimarães et al. PEPTIDES
- Decreased hepatic gluconeogenesis in transgenic rats with increased circulating angiotensin-(1-7)
- (2012) Victor Bilman et al. PEPTIDES
- Angiotensin-(1–7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts
- (2012) LaTronya T. McCollum et al. PEPTIDES
- Regulation of the renin-angiotensin system (RAS) in BeWo and HTR-8/SVneo trophoblast cell lines
- (2012) Y. Wang et al. PLACENTA
- Adenoviral Delivery of Angiotensin-(1-7) or Angiotensin-(1-9) Inhibits Cardiomyocyte Hypertrophy via the Mas or Angiotensin Type 2 Receptor
- (2012) Monica Flores-Muñoz et al. PLoS One
- Angiotensin-(1–7) in Paraventricular Nucleus Modulates Sympathetic Activity and Cardiac Sympathetic Afferent Reflex in Renovascular Hypertensive Rats
- (2012) Ying Han et al. PLoS One
- Angiotensin II and Angiotensin-(1-7) in Paraventricular Nucleus Modulate Cardiac Sympathetic Afferent Reflex in Renovascular Hypertensive Rats
- (2012) Hai-Jian Sun et al. PLoS One
- The Mas receptor mediates modulation of insulin signaling by angiotensin-(1–7)
- (2012) Marina C. Muñoz et al. REGULATORY PEPTIDES
- Angiotensin-(1-7) receptor Mas is an essential modulator of extracellular matrix protein expression in the heart
- (2012) Elisandra Gava et al. REGULATORY PEPTIDES
- Increased circulating angiotensin-(1–7) protects white adipose tissue against development of a proinflammatory state stimulated by a high-fat diet
- (2012) Sérgio Henrique S. Santos et al. REGULATORY PEPTIDES
- Counteraction between angiotensin II and angiotensin-(1–7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells
- (2012) Hong Xue et al. REGULATORY PEPTIDES
- Oral administration of an angiotensin-converting enzyme 2 activator ameliorates diabetes-induced cardiac dysfunction
- (2012) Tatiane M. Murça et al. REGULATORY PEPTIDES
- Modifications in basal and stress-induced hypothalamic AMP-activated protein kinase (AMPK) activity in rats chronically treated with an angiotensin II receptor blocker
- (2012) Mirna B. Marques et al. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
- Impact of ACE2 Deficiency and Oxidative Stress on Cerebrovascular Function With Aging
- (2012) Ricardo A. Peña Silva et al. STROKE
- The Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas receptor axis: A potential target for treating thrombotic diseases
- (2012) Rodrigo Fraga-Silva et al. THROMBOSIS AND HAEMOSTASIS
- Renoprotective Effects of AVE0991, a Nonpeptide Mas Receptor Agonist, in Experimental Acute Renal Injury
- (2012) Lívia Corrêa Barroso et al. International Journal of Hypertension
- Beneficial Effects of Long-Term Administration of an Oral Formulation of Angiotensin-(1–7) in Infarcted Rats
- (2012) Fúlvia D. Marques et al. International Journal of Hypertension
- Angiotensin-(1-7)-Mediated Signaling in Cardiomyocytes
- (2012) Enéas R. M. Gomes et al. International Journal of Hypertension
- Angiotensin-converting enzyme 2 overexpression improves central nitric oxide-mediated sympathetic outflow in chronic heart failure
- (2011) Hong Zheng et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Inhibition of Mas G-protein signaling improves coronary blood flow, reduces myocardial infarct size, and provides long-term cardioprotection
- (2011) Tong Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Angiotensin-(1–7) attenuates the chronotropic response to angiotensin II via stimulation of PTEN in the spontaneously hypertensive rat neurons
- (2011) Amit Modgil et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Review: Novel roles of nuclear angiotensin receptors and signaling mechanisms
- (2011) TanYa M. Gwathmey et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Chronic exercise modulates RAS components and improves balance between pro- and anti-inflammatory cytokines in the brain of SHR
- (2011) Deepmala Agarwal et al. BASIC RESEARCH IN CARDIOLOGY
- Role of Angiotensin-(1-7) in Rostral Ventrolateral Medulla in Blood Pressure Regulation via Sympathetic Nerve Activity in Wistar-Kyoto and Spontaneous Hypertensive Rats
- (2011) Toshiaki Nakagaki et al. CLINICAL AND EXPERIMENTAL HYPERTENSION
- An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect
- (2011) Rodrigo Araujo Fraga-Silva et al. Clinics
- Angiotensin peptides and central autonomic regulation
- (2011) Debra I Diz et al. CURRENT OPINION IN PHARMACOLOGY
- Angiotensin-(1-7) induces ovulation and steroidogenesis in perfused rabbit ovaries
- (2011) Gregorio E. N. Viana et al. EXPERIMENTAL PHYSIOLOGY
- Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke
- (2011) Adam P. Mecca et al. EXPERIMENTAL PHYSIOLOGY
- Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology
- (2011) YanFei Qi et al. EXPERIMENTAL PHYSIOLOGY
- Accelerated healing of diabetic wounds by NorLeu3-angiotensin (1-7)
- (2011) Kathleen Rodgers et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Role of ACE2 in diastolic and systolic heart failure
- (2011) Wang Wang et al. HEART FAILURE REVIEWS
- Brain-Selective Overexpression of Angiotensin-Converting Enzyme 2 Attenuates Sympathetic Nerve Activity and Enhances Baroreflex Function in Chronic Heart Failure
- (2011) Liang Xiao et al. HYPERTENSION
- Central Angiotensin (1-7) Enhances Baroreflex Gain in Conscious Rabbits With Heart Failure
- (2011) Sumit Kar et al. HYPERTENSION
- Angiotensin-Converting Enzyme 2 Deficiency Is Associated With Impaired Gestational Weight Gain and Fetal Growth Restriction
- (2011) Manish S. Bharadwaj et al. HYPERTENSION
- An Oral Formulation of Angiotensin-(1-7) Produces Cardioprotective Effects in Infarcted and Isoproterenol-Treated Rats
- (2011) Fúlvia D. Marques et al. HYPERTENSION
- Angiotensin-converting enzyme inhibition, but not AT1 receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats
- (2011) Katsunori Isa et al. HYPERTENSION RESEARCH
- Angiotensin-(1-7) decreases LPS-induced inflammatory response in macrophages
- (2011) Laura L. Souza et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The Angiotensin-(1-7)/Mas Receptor Axis Is Expressed in Sinoatrial Node Cells of Rats
- (2011) Anderson J. Ferreira et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Angiotensin-(1-7) through Mas receptor up-regulates neuronal norepinephrine transporter via Akt and Erk1/2-dependent pathways
- (2011) María A. Lopez Verrilli et al. JOURNAL OF NEUROCHEMISTRY
- Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist
- (2011) Roelie M Wösten-van Asperen et al. JOURNAL OF PATHOLOGY
- Mas receptors in modulating relaxation induced by perivascular adipose tissue
- (2011) Robert M.K.W. Lee et al. LIFE SCIENCES
- Angiotensin-(1–7)/Mas axis integrity is required for the expression of object recognition memory
- (2011) Thiago L.N. Lazaroni et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Different Isoforms of Nitric Oxide Synthase Are Involved in Angiotensin-(1–7)-Mediated Plasticity Changes in the Amygdala in a Gender-Dependent Manner
- (2011) Jörg Staschewski et al. NEUROENDOCRINOLOGY
- Angiotensin-(1-7) inhibits the migration and invasion of A549 human lung adenocarcinoma cells through inactivation of the PI3K/Akt and MAPK signaling pathways
- (2011) Huanying Wan ONCOLOGY REPORTS
- Angiotensin-(1–7) Mas-receptor deficiency decreases peroxisome proliferator-activated receptor gamma expression in adipocytes
- (2011) Érica Guilhen Mario et al. PEPTIDES
- ACE2-Mediated Reduction of Oxidative Stress in the Central Nervous System Is Associated with Improvement of Autonomic Function
- (2011) Huijing Xia et al. PLoS One
- Brain renin-angiotensin—A new look at an old system
- (2011) John W. Wright et al. PROGRESS IN NEUROBIOLOGY
- The Effect of the Thioether-Bridged, Stabilized Angiotensin-(1–7) Analogue Cyclic Ang-(1–7) on Cardiac Remodeling and Endothelial Function in Rats with Myocardial Infarction
- (2011) Matej Durik et al. International Journal of Hypertension
- Angiotensin-(1–7) improves cardiac remodeling and inhibits growth-promoting pathways in the heart of fructose-fed rats
- (2010) Jorge F. Giani et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Angiotensin-(1–7) upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats
- (2010) María A. Costa et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The Angiotensin-Converting Enzyme 2/Angiogenesis-(1–7)/Mas Axis Confers Cardiopulmonary Protection against Lung Fibrosis and Pulmonary Hypertension
- (2010) Vinayak Shenoy et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Improved Lipid and Glucose Metabolism in Transgenic Rats With Increased Circulating Angiotensin-(1-7)
- (2010) Sérgio Henrique S. Santos et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea
- (2010) Ana Quenia Gomes da Silva et al. BRAIN RESEARCH
- Characterization of angiotensin-converting enzymes 1 and 2 in the soleus and plantaris muscles of rats
- (2010) T. Fernandes et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
- Angiotensin-(1-7) Reduces Fibrosis in Orthotopic Breast Tumors
- (2010) K. L. Cook et al. CANCER RESEARCH
- Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla
- (2010) Fang Guo et al. CARDIOVASCULAR RESEARCH
- Impairment of Cardiac Function and Remodeling Induced by Myocardial Infarction in Rats are Attenuated by the Nonpeptide Angiotensin-(1-7) Analog AVE 0991
- (2010) Wu-tao Zeng et al. Cardiovascular Therapeutics
- Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse
- (2010) Merlin C. Thomas et al. CIRCULATION RESEARCH
- Circulating Rather Than Cardiac Angiotensin-(1-7) Stimulates Cardioprotection After Myocardial Infarction
- (2010) Yong Wang et al. Circulation-Heart Failure
- Angiotensin-(1–7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy
- (2010) Elena Velkoska et al. CLINICAL SCIENCE
- Angiotensin-(1–7) prevents diabetes-induced attenuation in PPAR-γ and catalase activities
- (2010) Gursev S. Dhaunsi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Angiotensin-(1-7), its receptor Mas, and the angiotensin-converting enzyme type 2 are expressed in the human ovary
- (2010) Fernando M. Reis et al. FERTILITY AND STERILITY
- The nonpeptide AVE0991 attenuates myocardial hypertrophy as induced by angiotensin II through downregulation of transforming growth factor-β1/Smad2 expression
- (2010) Jian-Gui He et al. HEART AND VESSELS
- Vascular Relaxation, Antihypertensive Effect, and Cardioprotection of a Novel Peptide Agonist of the Mas Receptor
- (2010) Silvia Quintão Savergnini et al. HYPERTENSION
- Lifetime Overproduction of Circulating Angiotensin-(1-7) Attenuates Deoxycorticosterone Acetate-Salt Hypertension-Induced Cardiac Dysfunction and Remodeling
- (2010) Nívia M. Santiago et al. HYPERTENSION
- Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice
- (2010) Atsushi Shiota et al. HYPERTENSION RESEARCH
- Exercise training normalizes ACE and ACE2 in the brain of rabbits with pacing-induced heart failure
- (2010) Sumit Kar et al. JOURNAL OF APPLIED PHYSIOLOGY
- Impairment of the angiotensin-converting enzyme 2–angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension
- (2010) Marcela Bürgelová et al. JOURNAL OF HYPERTENSION
- Anti-Inflammatory Effects of the Activation of the Angiotensin-(1-7) Receptor, Mas, in Experimental Models of Arthritis
- (2010) K. D. da Silveira et al. JOURNAL OF IMMUNOLOGY
- Targeting the ACE2–Ang-(1–7) pathway in cardiac fibroblasts to treat cardiac remodeling and heart failure
- (2010) Michikado Iwata et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Angiotensin (1–7) and its receptor Mas are expressed in the human testis: implications for male infertility
- (2010) Augusto B. Reis et al. JOURNAL OF MOLECULAR HISTOLOGY
- Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor
- (2010) M. Flores-Muñoz et al. JOURNAL OF PHYSIOLOGY-LONDON
- Knockout of Angiotensin 1–7 Receptor Mas Worsens the Course of Two-Kidney, One-Clip Goldblatt Hypertension: Roles of Nitric Oxide Deficiency and Enhanced Vascular Responsiveness to Angiotensin II
- (2010) Dan Rakušan et al. KIDNEY & BLOOD PRESSURE RESEARCH
- Ameliorative potential of angiotensin1-7/Mas receptor axis in streptozotocin-induced diabetic nephropathy in rats
- (2010) K. Kamal et al. METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
- Unknown
- (2010) Rodrigo Fraga-Silva et al. MOLECULAR MEDICINE
- Angiotensin-(1–7) attenuates hyposmolarity-induced ANP secretion via the Na+–K+ pump
- (2010) Amin Shah et al. PEPTIDES
- Altered cardiovascular reflexes responses in conscious Angiotensin-(1-7) receptor Mas-knockout mice
- (2010) Marina Matos de Moura et al. PEPTIDES
- Angiotensin-(1–7) and angiotension II in the rostral ventrolateral medulla modulate the cardiac sympathetic afferent reflex and sympathetic activity in rats
- (2010) Li-Min Zhou et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Role of the renin angiotensin system on bone marrow-derived stem cell function and its impact on skeletal muscle angiogenesis
- (2010) Micheline M. de Resende et al. PHYSIOLOGICAL GENOMICS
- Angiotensin-(1–7) prevents atrial fibrosis and atrial fibrillation in long-term atrial tachycardia dogs
- (2010) Enzhao Liu et al. REGULATORY PEPTIDES
- Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas
- (2010) Marina C. Muñoz et al. REGULATORY PEPTIDES
- High sucrose intake in rats is associated with increased ACE2 and angiotensin-(1–7) levels in the adipose tissue
- (2010) Michella Soares Coelho et al. REGULATORY PEPTIDES
- Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2
- (2009) Chandana B. Herath et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension
- (2009) Anderson J. Ferreira et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Chronic angiotensin-(1–7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits
- (2009) Wutao Zeng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Brain-Selective Overexpression of Human Angiotensin-Converting Enzyme Type 2 Attenuates Neurogenic Hypertension
- (2009) Yumei Feng et al. CIRCULATION RESEARCH
- Loss of Angiotensin-Converting Enzyme 2 Accelerates Maladaptive Left Ventricular Remodeling in Response to Myocardial Infarction
- (2009) Zamaneh Kassiri et al. Circulation-Heart Failure
- Angiotensin-(1–7), an alternative metabolite of the renin–angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat
- (2009) John S. Lubel et al. CLINICAL SCIENCE
- Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice
- (2009) Christoph H. Österreicher et al. HEPATOLOGY
- Effects of Angiotensin Metabolites in the Coronary Vascular Bed of the Spontaneously Hypertensive Rat
- (2009) Els Moltzer et al. HYPERTENSION
- Angiotensin-(1-7) Prevents Cardiomyocyte Pathological Remodeling Through a Nitric Oxide/Guanosine 3′,5′-Cyclic Monophosphate–Dependent Pathway
- (2009) Enéas R.M. Gomes et al. HYPERTENSION
- Angiotensin (1−7) prevent heart dysfunction and left ventricular remodeling caused by renal dysfunction in 5/6 nephrectomy mice
- (2009) Yiwen Li et al. HYPERTENSION RESEARCH
- Enalapril, irbesartan, and angiotensin-(1–7) prevent atrial tachycardia-induced ionic remodeling
- (2009) Enzhao Liu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- The role of angiotensin-(1-7) receptor Mas in spermatogenesis in mice and rats
- (2009) Marcelo C. Leal et al. JOURNAL OF ANATOMY
- Angiotensin-(1-7) and Baroreflex Function in Nucleus Tractus Solitarii of (mRen2)27 Transgenic Rats
- (2009) Debra I Diz et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Angiotensin-(1-7) through AT2receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway
- (2009) María A. Lopez Verrilli et al. JOURNAL OF NEUROCHEMISTRY
- Differential Virological and Immunological Outcome of Severe Acute Respiratory Syndrome Coronavirus Infection in Susceptible and Resistant Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2
- (2009) N. Yoshikawa et al. JOURNAL OF VIROLOGY
- Genetic deletion of the angiotensin-(1–7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria
- (2009) Sérgio V.B. Pinheiro et al. KIDNEY INTERNATIONAL
- Cell swelling, impulse conduction, and cardiac arrhythmias in the failing heart. Opposite effects of angiotensin II and angiotensin (1–7) on cell volume regulation
- (2009) Walmor C. De Mello MOLECULAR AND CELLULAR BIOCHEMISTRY
- Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells
- (2009) E. Gava et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Angiotensin-(1-7) antagonist, A-779, microinjection into the caudal ventrolateral medulla of renovascular hypertensive rats restores baroreflex bradycardia
- (2009) Luiza Michelle Cangussu et al. PEPTIDES
- Angiotensin-(1–7) and the G Protein-Coupled Receptor Mas Are Key Players in Renal Inflammation
- (2009) Vanesa Esteban et al. PLoS One
- Gonadotropin Stimulation Increases the Expression of Angiotensin-(1—7) and Mas Receptor in the Rat Ovary
- (2009) Virgínia M. Pereira et al. Reproductive Sciences
- Angiotensin-(1-7) and Its Effects in the Kidney
- (2009) Marc Dilauro et al. TheScientificWorldJOURNAL
- Relationship between angiotensin-(1-7) and angiotensin II correlates with hemodynamic changes in human liver cirrhosis
- (2009) Walkíria Wingester Vilas-Boas et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Chronic angiotensin (17) injection accelerates STZ-induced diabetic renal injury1
- (2008) Ying SHAO et al. ACTA PHARMACOLOGICA SINICA
- Chronic infusion of angiotensin-(1–7) improves insulin resistance and hypertension induced by a high-fructose diet in rats
- (2008) Jorge F. Giani et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Regulation of ACE2 in cardiac myocytes and fibroblasts
- (2008) Patricia E. Gallagher et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis
- (2008) Fina Lovren et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Angiotensin-(1-7) serves as an aquaretic by increasing water intake and diuresis in association with downregulation of aquaporin-1 during pregnancy in rats
- (2008) J. Joyner et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Gender differences in the effects of antenatal betamethasone exposure on renal function in adult sheep
- (2008) Lijun Tang et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- The Angiotensin Converting Enzyme 2/Ang-(1-7) Axis in the Heart
- (2008) James A. Stewart et al. CIRCULATION RESEARCH
- Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the Heart
- (2008) Chantal Mercure et al. CIRCULATION RESEARCH
- The angiotensin-(1–7) receptor agonist AVE0991 is cardioprotective in diabetic rats
- (2008) Linda Ebermann et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Selective increase of angiotensin(1-7) and its receptor in hearts of spontaneously hypertensive rats subjected to physical training
- (2008) Ary Gomes Filho et al. EXPERIMENTAL PHYSIOLOGY
- Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats
- (2008) Debra I. Diz et al. EXPERIMENTAL PHYSIOLOGY
- Angiotensin-converting enzyme 2 gene targeting studies in mice: mixed messages
- (2008) Susan B. Gurley et al. EXPERIMENTAL PHYSIOLOGY
- The angiotensin receptor type 1-Gqprotein-phosphatidyl inositol phospholipase Cβ-protein kinase C pathway is involved in activation of proximal tubule Na+-ATPase activity by angiotensin(1-7) in pig kidneys
- (2008) Lucienne S. Lara et al. EXPERIMENTAL PHYSIOLOGY
- Angiotensin-(1-7) has a dual role on growth-promoting signalling pathways in rat heart in vivo by stimulating STAT3 and STAT5a/b phosphorylation and inhibiting angiotensin II-stimulated ERK1/2 and Rho kinase activity
- (2008) J. F. Giani et al. EXPERIMENTAL PHYSIOLOGY
- Role of angiotensin-converting enzyme 2 and angiotensin(1-7) in 17β-oestradiol regulation of renal pathology in renal wrap hypertension in rats
- (2008) Hong Ji et al. EXPERIMENTAL PHYSIOLOGY
- A protein complex in the brush-border membrane explains a Hartnup disorder allele
- (2008) Sonja Kowalczuk et al. FASEB JOURNAL
- Transgenic Angiotensin-Converting Enzyme 2 Overexpression in Vessels of SHRSP Rats Reduces Blood Pressure and Improves Endothelial Function
- (2008) Brit Rentzsch et al. HYPERTENSION
- Endothelial Dysfunction and Elevated Blood Pressure in Mas Gene-Deleted Mice
- (2008) Ping Xu et al. HYPERTENSION
- Activation of Local Chorionic Villi Angiotensin II Levels But Not Angiotensin (1-7) in Preeclampsia
- (2008) Lauren Anton et al. HYPERTENSION
- Modulation of Reflex Function by Endogenous Angiotensins in Older Transgenic Rats With Low Glial Angiotensinogen
- (2008) Amy C. Arnold et al. HYPERTENSION
- Molecular Mechanisms Involved in the Angiotensin-(1-7)/Mas Signaling Pathway in Cardiomyocytes
- (2008) Marco F. Dias-Peixoto et al. HYPERTENSION
- Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents
- (2008) José A. Hernández Prada et al. HYPERTENSION
- Liver disease and the renin-angiotensin system: Recent discoveries and clinical implications
- (2008) John S Lubel et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Angiotensin-(1-7) with Thioether Bridge: An Angiotensin-Converting Enzyme-Resistant, Potent Angiotensin-(1-7) Analog
- (2008) L. D. Kluskens et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Ablation of angiotensin (1-7) receptor Mas in C57Bl/6 mice causes endothelial dysfunction
- (2008) Luiza A. Rabelo et al. Journal of the American Society of Hypertension
- Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1–7)3292 rats
- (2008) Ana Paula Nadu et al. Journal of the American Society of Hypertension
- Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2
- (2008) J. Netland et al. JOURNAL OF VIROLOGY
- Angiotensin metabolites can stimulate receptors of the Mas-related genes family
- (2008) Florian Gembardt et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Unknown
- (2008) Rodrigo Fraga-Silva et al. MOLECULAR MEDICINE
- Central administration of angiotensin-(1–7) stimulates nitric oxide release and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats
- (2008) Yingdong Zhang et al. NEUROPEPTIDES
- Cardiac cachexia: A systematic overview
- (2008) Stephan von Haehling et al. PHARMACOLOGY & THERAPEUTICS
- An Intracellular Renin-Angiotensin System in Neurons: Fact, Hypothesis, or Fantasy
- (2008) Justin L. Grobe et al. PHYSIOLOGY
- ACE2 and ANG-(1-7) in the rat uterus during early and late gestation
- (2007) Liomar A. A. Neves et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Hemodynamic effect produced by microinjection of angiotensins at the caudal ventrolateral medulla of spontaneously hypertensive rats
- (2007) P.M. Ferreira et al. NEUROSCIENCE
- Involvement of angiotensin-(1–7) in the hypothalamic hypotensive effect of captopril in sinoaortic denervated rats
- (2007) Christian Höcht et al. REGULATORY PEPTIDES
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