Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension

Angiotensin II Up-Regulates Angiotensin I-Converting Enzyme (ACE), but Down-Regulates ACE2 via the AT1-ERK/p38 MAP Kinase Pathway

(2008) Vijay Koka et al.   AMERICAN JOURNAL OF PATHOLOGY

Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice

(2008) Yanli Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin converting enzyme-2 is protective but downregulated in human and experimental lung fibrosis

(2008) Xiaopeng Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Circulating Endothelial Microparticle Levels Predict Hemodynamic Severity of Pulmonary Hypertension

(2008) Nicolas Amabile et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pulmonary Hypertension, Right Ventricular Failure, and Kidney: Different from Left Ventricular Failure?

(2008) R. W. Schrier et al.   Clinical Journal of the American Society of Nephrology

Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents

(2008) José A. Hernández Prada et al.   HYPERTENSION

Molecular pathogenesis of pulmonary arterial hypertension

(2008) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

Pulmonary Arterial Hypertension

(2008) Kelly M. Chin et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Role of the renin–angiotensin system in vascular inflammation

(2008) Chiara Marchesi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Pathogenic mechanisms of pulmonary arterial hypertension

(2007) Stephen Y. Chan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY