The Ang-(1–7)/Mas-1 axis attenuates the expression and signalling of TGF-β1 induced by AngII in mouse skeletal muscle

Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD- and p38 MAPK-dependent mechanism in skeletal muscle

(2013) Paula Painemal et al.   BIOFACTORS

Angiotensin (1–7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs

(2013) Eliezer Joseph Tassone et al.   CARDIOVASCULAR RESEARCH

Inhibition of the angiotensin-converting enzyme decreases skeletal muscle fibrosis in dystrophic mice by a diminution in the expression and activity of connective tissue growth factor (CTGF/CCN-2)

(2013) María Gabriela Morales et al.   CELL AND TISSUE RESEARCH

Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans

(2013) Felipe Simon et al.   CELLULAR SIGNALLING

Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling

(2013) María José Acuña et al.   HUMAN MOLECULAR GENETICS

Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells

(2013) César Echeverría et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Prolonged treatment with angiotensin 1–7 improves endothelial function in diet-induced obesity

(2013) Andreas M. Beyer et al.   JOURNAL OF HYPERTENSION

Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury

(2013) Qiuhua Chen et al.   JOURNAL OF SURGICAL RESEARCH

Angiotensin II: Role in Skeletal Muscle Atrophy

(2012) Claudio Cabello-Verrugio et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Therapeutic targeting of the angiotensin-converting enzyme 2/Angiotensin-(1-7)/Mas cascade in the renin–angiotensin system: a patent review

(2012) Anderson J Ferreira et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Angiotensin II-induced pro-fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells

(2012) María Gabriela Morales et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Contribution of oxidative stress to pathology in diaphragm and limb muscles with Duchenne muscular dystrophy

(2012) Jong-Hee Kim et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Angiotensin-(1–7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts

(2012) LaTronya T. McCollum et al.   PEPTIDES

The Mas receptor mediates modulation of insulin signaling by angiotensin-(1–7)

(2012) Marina C. Muñoz et al.   REGULATORY PEPTIDES

Acute and chronic angiotensin-(1–7) restores vasodilation and reduces oxidative stress in mesenteric arteries of salt-fed rats

(2011) Gábor Raffai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin-(1–7) attenuates angiotensin II-induced cardiac remodeling associated with upregulation of dual-specificity phosphatase 1

(2011) LaTronya T. McCollum et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin II-induced reduction in exercise capacity is associated with increased oxidative stress in skeletal muscle

(2011) Naoki Inoue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Increased Expression of the Transient Receptor Potential Melastatin 7 Channel Is Critically Involved in Lipopolysaccharide-Induced Reactive Oxygen Species-Mediated Neuronal Death

(2011) Felipe Nuñez-Villena et al.   ANTIOXIDANTS & REDOX SIGNALING

Fibrotic response induced by angiotensin-II requires NAD(P)H oxidase-induced reactive oxygen species (ROS) in skeletal muscle cells

(2011) Claudio Cabello-Verrugio et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death

(2011) Alvaro Becerra et al.   CARDIOVASCULAR RESEARCH

Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles

(2011) Claudio Cabello-Verrugio et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis

(2011) Christopher L. Mendias et al.   MUSCLE & NERVE

Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice

(2011) Anna Cozzoli et al.   PHARMACOLOGICAL RESEARCH

Losartan Restores Skeletal Muscle Remodeling and Protects Against Disuse Atrophy in Sarcopenia

(2011) T. N. Burks et al.   Science Translational Medicine

Angiotensin Receptor Blockers: Role in Hypertension Management, Cardiovascular Risk Reduction, and Nephropathy

(2011) Jan Basile et al.   SOUTHERN MEDICAL JOURNAL

Connective tissue growth factor induction by lysophosphatidic acid requires transactivation of transforming growth factor type β receptors and the JNK pathway

(2010) Claudio Cabello-Verrugio et al.   CELLULAR SIGNALLING

Angiotensin-(1–7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy

(2010) Elena Velkoska et al.   CLINICAL SCIENCE

TGF-β receptors, in a Smad-independent manner, are required for terminal skeletal muscle differentiation

(2010) Rebeca Droguett et al.   EXPERIMENTAL CELL RESEARCH

The nonpeptide AVE0991 attenuates myocardial hypertrophy as induced by angiotensin II through downregulation of transforming growth factor-β1/Smad2 expression

(2010) Jian-Gui He et al.   HEART AND VESSELS

The counterregulating role of ACE2 and ACE2-mediated angiotensin 1–7 signaling against angiotensin II stimulation in vascular cells

(2010) Norihiro Hayashi et al.   HYPERTENSION RESEARCH

Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas

(2010) Marina C. Muñoz et al.   REGULATORY PEPTIDES

Angiotensin-(1–7) ameliorates myocardial remodeling and interstitial fibrosis in spontaneous hypertension: Role of MMPs/TIMPs

(2010) Zhaohui Pei et al.   TOXICOLOGY LETTERS

Chronic angiotensin-(1–7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits

(2009) Wutao Zeng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Devil and angel in the renin–angiotensin system: ACE–angiotensin II–AT1 receptor axis vs. ACE2–angiotensin-(1–7)–Mas receptor axis

(2009) Masaru Iwai et al.   HYPERTENSION RESEARCH

Early lipopolysaccharide-induced reactive oxygen species production evokes necrotic cell death in human umbilical vein endothelial cells

(2009) Felipe Simon et al.   JOURNAL OF HYPERTENSION

Angiotensin-(1-7) inhibits tumor angiogenesis in human lung cancer xenografts with a reduction in vascular endothelial growth factor

(2009) D. R. Soto-Pantoja et al.   MOLECULAR CANCER THERAPEUTICS

Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells

(2009) E. Gava et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Angiotensin-(1-7) as an antihypertensive, antifibrotic target

(2008) Michael J. Katovich et al.   CURRENT HYPERTENSION REPORTS

Protein Kinase C–Mediated Phosphorylation of p47phoxModulates Platelet-Derived Growth Factor–Induced H2O2Generation and Cell Proliferation in Human Umbilical Vein Endothelial Cells

(2008) F. Simon et al.   ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH

Endothelial Dysfunction and Elevated Blood Pressure in Mas Gene-Deleted Mice

(2008) Ping Xu et al.   HYPERTENSION

Liver disease and the renin-angiotensin system: Recent discoveries and clinical implications

(2008) John S Lubel et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Renin-angiotensin system revisited

(2008) F. Fyhrquist et al.   JOURNAL OF INTERNAL MEDICINE