Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling

Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy

(2013) Maria Gabriela Morales et al.   HUMAN MOLECULAR GENETICS

PAI-1–regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy

(2012) Esther Ardite et al.   JOURNAL OF CELL BIOLOGY

Angiotensin-converting enzyme 2, angiotensin-(1–7) and Mas: new players of the renin–angiotensin system

(2012) Robson A S Santos et al.   JOURNAL OF ENDOCRINOLOGY

Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis

(2012) Lijun Wang et al.   MOLECULAR THERAPY

Inhibition of miR-29 by TGF-beta-Smad3 Signaling through Dual Mechanisms Promotes Transdifferentiation of Mouse Myoblasts into Myofibroblasts

(2012) Liang Zhou et al.   PLoS One

The Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas receptor axis: A potential target for treating thrombotic diseases

(2012) Rodrigo Fraga-Silva et al.   THROMBOSIS AND HAEMOSTASIS

Losartan, a therapeutic candidate in congenital muscular dystrophy: Studies in the dy2J/dy2J Mouse

(2011) Moran Elbaz et al.   ANNALS OF NEUROLOGY

An Oral Formulation of Angiotensin-(1-7) Produces Cardioprotective Effects in Infarcted and Isoproterenol-Treated Rats

(2011) Fúlvia D. Marques et al.   HYPERTENSION

The Internal Region Leucine-rich Repeat 6 of Decorin Interacts with Low Density Lipoprotein Receptor-related Protein-1, Modulates Transforming Growth Factor (TGF)-β-dependent Signaling, and Inhibits TGF-β-dependent Fibrotic Response in Skeletal Muscles

(2011) Claudio Cabello-Verrugio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy

(2011) María Gabriela Morales et al.   JOURNAL OF PATHOLOGY

Losartan Restores Skeletal Muscle Remodeling and Protects Against Disuse Atrophy in Sarcopenia

(2011) T. N. Burks et al.   Science Translational Medicine

Role of TGF-β signaling in inherited and acquired myopathies

(2011) Tyesha N Burks et al.   Skeletal Muscle

Aberrant repair and fibrosis development in skeletal muscle

(2011) Christopher J Mann et al.   Skeletal Muscle

ACE2: more of Ang-(1–7) or less Ang II?

(2010) Carlos M Ferrario   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Connective tissue fibroblasts and Tcf4 regulate myogenesis

(2010) S. J. Mathew et al.   DEVELOPMENT

Regulation and dysregulation of fibrosis in skeletal muscle

(2010) Antonio L. Serrano et al.   EXPERIMENTAL CELL RESEARCH

Targeting Fibrosis in Duchenne Muscular Dystrophy

(2010) Lan Zhou et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A Novel Mechanism of Sequestering Fibroblast Growth Factor 2 by Glypican in Lipid Rafts, Allowing Skeletal Muscle Differentiation

(2010) J. Gutierrez et al.   MOLECULAR AND CELLULAR BIOLOGY

Devil and angel in the renin–angiotensin system: ACE–angiotensin II–AT1 receptor axis vs. ACE2–angiotensin-(1–7)–Mas receptor axis

(2009) Masaru Iwai et al.   HYPERTENSION RESEARCH

Renin-angiotensin system in the pathogenesis of liver fibrosis

(2009) Regina Maria Pereira et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Transforming growth factor-β and myostatin signaling in skeletal muscle

(2007) Helen D. Kollias et al.   JOURNAL OF APPLIED PHYSIOLOGY

Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation

(2007) Cecilia Vial et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY