Hypothalamic endoplasmic reticulum stress as a key mediator of obesity-induced leptin resistance

The endoplasmic reticulum: A hub of protein quality control in health and disease

(2017) Lisa Vincenz-Donnelly et al.   FREE RADICAL BIOLOGY AND MEDICINE

Obesity is more closely related with hepatic steatosis and fibrosis measured by transient elastography than metabolic health status

(2017) Ji Hye Huh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Management of cardiovascular diseases in patients with obesity

(2017) Carl J. Lavie et al.   Nature Reviews Cardiology

Immunometabolism: ER stress drives obesity by reducing energy expenditure

(2017) David Holmes   Nature Reviews Endocrinology

The cellular and molecular bases of leptin and ghrelin resistance in obesity

(2017) Huxing Cui et al.   Nature Reviews Endocrinology

ER stress and the unfolded protein response in neurodegeneration

(2017) Claudio Hetz et al.   Nature Reviews Neurology

Adiposity and cancer at major anatomical sites: umbrella review of the literature

(2017) Maria Kyrgiou et al.   BMJ-British Medical Journal

ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity

(2017) Toru Suzuki et al.   Cell Reports

Adiposity and cancer at major anatomical sites: umbrella review of the literature

(2017) Maria Kyrgiou et al.   BMJ-British Medical Journal

Leptin-deficient mice are not hypothermic, they are anapyrexic

(2017) Alexander W. Fischer et al.   Molecular Metabolism

Blocking iNOS and endoplasmic reticulum stress synergistically improves insulin resistance in mice

(2017) Tamires M. Zanotto et al.   Molecular Metabolism

Impact of high cholesterol and endoplasmic reticulum stress on metabolic diseases: An updated mini-review

(2017) Erdi Sozen et al.   Redox Biology

Obesity

(2017) Pedro González-Muniesa et al.   Nature Reviews Disease Primers

Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction

(2017) Guifen Qiang et al.   Scientific Reports

Chemical chaperone, TUDCA unlike PBA, mitigates protein aggregation efficiently and resists ER and non-ER stress induced HepG2 cell death

(2017) Jagadeesh Kumar Uppala et al.   Scientific Reports

Targeting ceramide metabolism in obesity

(2016) Hanin Aburasayn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis

(2016) Hae-Youn Lee et al.   Autophagy

Leptin signalling pathways in hypothalamic neurons

(2016) Obin Kwon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain

(2016) Gurdeep Marwarha et al.   CELLULAR SIGNALLING

Energy balance, body composition, sedentariness and appetite regulation: pathways to obesity

(2016) M. Hopkins et al.   CLINICAL SCIENCE

Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity

(2016) Cristina Contreras et al.   DIABETES

Ire1α in Pomc Neurons Is Required for Thermogenesis and Glycemia

(2016) Ting Yao et al.   DIABETES

Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice

(2016) Yuanyuan Li et al.   HEPATOLOGY

Proanthocyanidins potentiate hypothalamic leptin/STAT3 signalling and Pomc gene expression in rats with diet-induced obesity

(2016) M Ibars et al.   INTERNATIONAL JOURNAL OF OBESITY

High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons

(2016) P S Dalvi et al.   INTERNATIONAL JOURNAL OF OBESITY

Thyroid hormones induce browning of white fat

(2016) Noelia Martínez-Sánchez et al.   JOURNAL OF ENDOCRINOLOGY

Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperone

(2016) Abdelkrim Khadir et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Hypothalamus and thermogenesis: Heating the BAT, browning the WAT

(2016) Cristina Contreras et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endoplasmic reticulum stress regulates inflammation and insulin resistance in skeletal muscle from pregnant women

(2016) Stella Liong et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Minireview: CNS Mechanisms of Leptin Action

(2016) Jonathan N. Flak et al.   MOLECULAR ENDOCRINOLOGY

NOD1 and NOD2 signalling links ER stress with inflammation

(2016) A. Marijke Keestra-Gounder et al.   NATURE

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice

(2016) Jaemin Lee et al.   NATURE MEDICINE

Hypothalamic AMPK: a canonical regulator of whole-body energy balance

(2016) Miguel López et al.   Nature Reviews Endocrinology

Brown adipose tissue as a secretory organ

(2016) Francesc Villarroya et al.   Nature Reviews Endocrinology

Free fatty acid palmitate activates unfolded protein response pathway and promotes apoptosis in meniscus cells

(2016) J. Haywood et al.   OSTEOARTHRITIS AND CARTILAGE

White Adipose Tissue Browning: A Double-edged Sword

(2016) Abdikarim Abdullahi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation

(2016) Guifen Qiang et al.   Nature Communications

Leptin Raises Defended Body Temperature without Activating Thermogenesis

(2016) Alexander W. Fischer et al.   Cell Reports

Knockout of inositol-requiring enzyme 1α in pro-opiomelanocortin neurons decreases fat mass via increasing energy expenditure

(2016) Yuzhong Xiao et al.   Open Biology

The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane

(2016) Deng-Fu Guo et al.   PLoS Genetics

Chemical chaperones reduce ER stress and adipose tissue inflammation in high fat diet-induced mouse model of obesity

(2016) Yaqin Chen et al.   Scientific Reports

Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress

(2015) J. D. Mosinski et al.   Acta Physiologica

Treatment of Obesity with Celastrol

(2015) Junli Liu et al.   CELL

Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat

(2015) Garron T. Dodd et al.   CELL

Role of Mitofusin-2 in mitochondrial localization and calcium uptake in skeletal muscle

(2015) Alina Ainbinder et al.   CELL CALCIUM

Diet-Induced Obese Mice Retain Endogenous Leptin Action

(2015) Nickki Ottaway et al.   Cell Metabolism

The endoplasmic reticulum: structure, function and response to cellular signaling

(2015) Dianne S. Schwarz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Brown Adipose Tissue Transplantation Reverses Obesity in Ob/Ob Mice

(2015) Xiaomeng Liu et al.   ENDOCRINOLOGY

Drop in endo/sarcoplasmic calcium precedes the unfolded protein response in Brefeldin A-treated vascular smooth muscle cells

(2015) Gabriela Ziomek et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hypothalamic ER stress: A bridge between leptin resistance and obesity

(2015) Sara Ramírez et al.   FEBS LETTERS

Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders

(2015) Soojeong Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum Stress Interacts With Inflammation in Human Diseases

(2015) Stewart Siyan Cao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis

(2015) Anna Fernández et al.   JOURNAL OF PINEAL RESEARCH

Endoplasmic Reticulum Stress Response in Non-alcoholic Steatohepatitis: The Possible Role of Physical Exercise

(2015) Emanuel Passos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism

(2015) Hyeong-Kyu Park et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Proteostasis control by the unfolded protein response

(2015) Claudio Hetz et al.   NATURE CELL BIOLOGY

Microbiota depletion promotes browning of white adipose tissue and reduces obesity

(2015) Nicolas Suárez-Zamorano et al.   NATURE MEDICINE

Leptin resistance in diet-induced obesity: the role of hypothalamic inflammation

(2015) K. C. G. de Git et al.   Obesity Reviews

S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

(2015) L. Yang et al.   SCIENCE

Chronic Sleep Fragmentation During the Sleep Period Induces Hypothalamic Endoplasmic Reticulum Stress and PTP1b-Mediated Leptin Resistance in Male Mice

(2015) Fahed Hakim et al.   SLEEP

Targeting endoplasmic reticulum stress in insulin resistance

(2015) Laia Salvadó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Tunicamycin enhances the antitumor activity of trastuzumab on breast cancer in vitro and in vivo

(2015) Xiqian Han et al.   Oncotarget

Chronic Sleep Fragmentation During the Sleep Period Induces Hypothalamic Endoplasmic Reticulum Stress and PTP1b-Mediated Leptin Resistance in Male Mice

(2015) Fahed Hakim et al.   SLEEP

The brain and brown fat

(2014) Cristina Contreras et al.   ANNALS OF MEDICINE

Therapeutic potential of flurbiprofen against obesity in mice

(2014) Toru Hosoi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress

(2014) Byung-Hyun Cha et al.   BIOMATERIALS

Regulation of SERCA pumps expression in diabetes

(2014) Angel Zarain-Herzberg et al.   CELL CALCIUM

The Browning of White Adipose Tissue: Some Burning Issues

(2014) Jan Nedergaard et al.   Cell Metabolism

Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis

(2014) Kevin W. Williams et al.   Cell Metabolism

Nicotine Improves Obesity and Hepatic Steatosis and ER Stress in Diet-Induced Obese Male Rats

(2014) Patricia Seoane-Collazo et al.   ENDOCRINOLOGY

20 YEARS OF LEPTIN: Connecting leptin signaling to biological function

(2014) Margaret B Allison et al.   JOURNAL OF ENDOCRINOLOGY

Trigonelline and diosgenin attenuate ER stress, oxidative stress-mediated damage in pancreas and enhance adipose tissue PPARγ activity in type 2 diabetic rats

(2014) M. Tharaheswari et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Caffeine attenuated ER stress-induced leptin resistance in neurons

(2014) Toru Hosoi et al.   NEUROSCIENCE LETTERS

Advances in understanding the interrelations between leptin resistance and obesity

(2014) Haitao Pan et al.   PHYSIOLOGY & BEHAVIOR

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

(2014) M. Lu et al.   SCIENCE

Lipotoxic endoplasmic reticulum stress, β cell failure, and type 2 diabetes mellitus

(2014) Trevor J. Biden et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

(2014) Namrata Chaudhari et al.   Frontiers in Cellular Neuroscience

Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance

(2014) Eva Tsaousidou et al.   Cell Reports

Central Ceramide-Induced Hypothalamic Lipotoxicity and ER Stress Regulate Energy Balance

(2014) Cristina Contreras et al.   Cell Reports

Carbon monoxide-releasing molecules reverse leptin resistance induced by endoplasmic reticulum stress

(2013) Min Zheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitofusins: Mighty Regulators of Metabolism

(2013) Umut Ozcan   CELL

Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance

(2013) Marc Schneeberger et al.   CELL

Arcuate NPY Controls Sympathetic Output and BAT Function via a Relay of Tyrosine Hydroxylase Neurons in the PVN

(2013) Yan-Chuan Shi et al.   Cell Metabolism

Brown adipose tissue transplantation improves whole-body energy metabolism

(2013) Xiaomeng Liu et al.   CELL RESEARCH

Cell Death and Survival Through the Endoplasmic Reticulum- Mitochondrial Axis

(2013) R. Bravo-Sagua et al.   CURRENT MOLECULAR MEDICINE

Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis

(2013) H. Sha et al.   DIABETES

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

(2013) Juan Pablo Muñoz et al.   EMBO JOURNAL

Teasaponin Reduces Inflammation and Central Leptin Resistance in Diet-Induced Obese Male Mice

(2013) Yinghua Yu et al.   ENDOCRINOLOGY

Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response

(2013) Shotaro Nakajima et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways

(2013) Sena Kim et al.   Innate Immunity

Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing

(2013) Isin Çakir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance

(2013) Marc Schneeberger et al.   JOURNAL OF ENDOCRINOLOGY

High-Fat Diet Is Associated with Obesity-Mediated Insulin Resistance and β-Cell Dysfunction in Mexican Americans

(2013) Mary Helen Black et al.   JOURNAL OF NUTRITION

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

(2013) Chong Wee Liew et al.   NATURE MEDICINE

Potential for therapeutic manipulation of the UPR in disease

(2013) Sang Won Park et al.   Seminars in Immunopathology

The Role of Adipocyte XBP1 in Metabolic Regulation during Lactation

(2013) Margaret F. Gregor et al.   Cell Reports

Endoplasmic reticulum stress and the on site function of resident PTP1B

(2012) Doina Popov   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Challenges and Opportunities of Defining Clinical Leptin Resistance

(2012) Martin G. Myers et al.   Cell Metabolism

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

Role of Hypothalamic Proopiomelanocortin Neuron Autophagy in the Control of Appetite and Leptin Response

(2012) Wenying Quan et al.   ENDOCRINOLOGY

Increased Hypothalamic Inflammation Associated with the Susceptibility to Obesity in Rats Exposed to High-Fat Diet

(2012) Xiaoke Wang et al.   Experimental Diabetes Research

New insights into ER stress-induced insulin resistance

(2012) Mélissa Flamment et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Protein Folding and Modification in the Mammalian Endoplasmic Reticulum

(2011) Ineke Braakman et al.   Annual Review of Biochemistry

A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking

(2011) Ebru Boslem et al.   BIOCHEMICAL JOURNAL

Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance

(2011) Susmita Kaushik et al.   Cell Metabolism

The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex

(2011) Jun Wu et al.   Cell Metabolism

Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation

(2011) Shannon M. Harlan et al.   CIRCULATION RESEARCH

Leptin receptor signaling: pathways to leptin resistance

(2011) Joris Wauman   Frontiers in Bioscience-Landmark

Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

(2011) Qingyuan Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p38 MAPK–mediated regulation of Xbp1s is crucial for glucose homeostasis

(2011) Jaemin Lee et al.   NATURE MEDICINE

Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus

(2011) K. W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

H2S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response

(2011) N. Krishnan et al.   Science Signaling

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

Toll-like receptors, inflammation, metabolism and obesity

(2011) Manuel Fresno et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Contributions of SERCA pump and ryanodine-sensitive stores to presynaptic residual Ca2+

(2010) Chessa S. Scullin et al.   CELL CALCIUM

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

(2010) Sarah Hummasti et al.   CIRCULATION RESEARCH

Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases

(2010) F. Engin et al.   DIABETES OBESITY & METABOLISM

Leptin and hunger levels in young healthy adults after one night of sleep loss

(2010) SLOBODANKA PEJOVIC et al.   JOURNAL OF SLEEP RESEARCH

SF-1 in the ventral medial hypothalamic nucleus: A key regulator of homeostasis

(2010) Ki Woo Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

FFA-Induced Adipocyte Inflammation and Insulin Resistance: Involvement of ER Stress and IKKβ Pathways

(2010) Ping Jiao et al.   Obesity

Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity

(2010) S. W. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis

(2010) Matthew Stuible et al.   TRENDS IN CELL BIOLOGY

Toll-like receptors: linking inflammation to metabolism

(2010) A. Christine Könner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKβ and ER Stress Inhibition

(2010) Eduardo R. Ropelle et al.   PLOS BIOLOGY

Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance

(2009) Lale Ozcan et al.   Cell Metabolism

Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance

(2009) R. Ye et al.   DIABETES

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

(2009) Seongjin Seo et al.   HUMAN MOLECULAR GENETICS

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

(2009) Julie Hollien et al.   JOURNAL OF CELL BIOLOGY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Astragalus polysaccharides decreased the expression of PTP1B through relieving ER stress induced activation of ATF6 in a rat model of type 2 diabetes

(2009) Nian Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Homocysteine induces X-box-binding protein 1 splicing in the mice brain

(2009) Toru Hosoi et al.   NEUROCHEMISTRY INTERNATIONAL

Central Administration of an Endoplasmic Reticulum Stress Inducer Inhibits the Anorexigenic Effects of Leptin and Insulin

(2009) Jong Chul Won et al.   Obesity

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum

(2008) Yusuke Adachi et al.   CELL STRUCTURE AND FUNCTION

Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss

(2008) M. F. Gregor et al.   DIABETES

Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals

(2008) G. Boden et al.   DIABETES

Selective Loss of Leptin Receptors in the Ventromedial Hypothalamic Nucleus Results in Increased Adiposity and a Metabolic Syndrome

(2008) Nathan C. Bingham et al.   ENDOCRINOLOGY

Global burden of obesity in 2005 and projections to 2030

(2008) T Kelly et al.   INTERNATIONAL JOURNAL OF OBESITY

Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis

(2008) Umut Ozcan et al.   MOLECULAR CELL

Endoplasmic Reticulum Stress Induces Leptin Resistance

(2008) T. Hosoi et al.   MOLECULAR PHARMACOLOGY

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE