Endoplasmic Reticulum Stress Interacts With Inflammation in Human Diseases

Endoplasmic Reticulum Stress Aggravates Viral Myocarditis by Raising Inflammation Through the IRE1-Associated NF-κB Pathway

(2015) Xi Zha et al.   CANADIAN JOURNAL OF CARDIOLOGY

Parasite-induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection

(2015) P. Inacio et al.   EMBO REPORTS

Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1

(2015) M Reed et al.   Mucosal Immunology

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

(2015) Levi B Watkin et al.   NATURE GENETICS

Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia

(2015) Susanne Kohl et al.   NATURE GENETICS

Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

(2015) Audrey Filézac de L'Etang et al.   NATURE NEUROSCIENCE

Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway

(2015) Wayne I. Lencer et al.   TRENDS IN IMMUNOLOGY

Endoplasmic Reticulum Stress in Intestinal Epithelial Cell Function and Inflammatory Bowel Disease

(2015) Katherine Luo et al.   Gastroenterology Research and Practice

Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells

(2015) Emily F. A. van ‘t Wout et al.   PLoS Pathogens

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Deficiency of IRE1 and PERK Signal Pathways in Systemic Lupus Erythematosus

(2014) Qiyao Cheng et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism

(2014) Laia Salvadó et al.   DIABETOLOGIA

Genetic inactivation of PERK signaling in mouse oligodendrocytes: Normal developmental myelination with increased susceptibility to inflammatory demyelination

(2014) Yassir Hussien et al.   GLIA

Phosphorylation of eIF2α Is Dispensable for Differentiation but Required at a Posttranscriptional Level for Paneth Cell Function and Intestinal Homeostasis in Mice

(2014) Stewart S. Cao et al.   INFLAMMATORY BOWEL DISEASES

A pathogenic role for ER stress-induced autophagy and ER chaperone GRP78/BiP in T lymphocyte systemic lupus erythematosus

(2014) Won-Seok Lee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Evaluating the levels of interleukin-1 family cytokines in sporadic amyotrophic lateral sclerosis

(2014) Paola Italiani et al.   Journal of Neuroinflammation

The Endoplasmic Reticulum Stress Sensor IRE1  Protects Cells from Apoptosis Induced by the Coronavirus Infectious Bronchitis Virus

(2014) T. S. Fung et al.   JOURNAL OF VIROLOGY

PERK-Dependent Activation of JAK1 and STAT3 Contributes to Endoplasmic Reticulum Stress-Induced Inflammation

(2014) G. P. Meares et al.   MOLECULAR AND CELLULAR BIOLOGY

β-Arrestin2 encourages inflammation-induced epithelial apoptosis through ER stress/PUMA in colitis

(2014) L X Zeng et al.   Mucosal Immunology

Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress

(2014) Sumaira Z Hasnain et al.   NATURE MEDICINE

Differential Regulation of Glutamate Transporter Subtypes by Pro-Inflammatory Cytokine TNF-α in Cortical Astrocytes from a Rat Model of Amyotrophic Lateral Sclerosis

(2014) Amélie O. Dumont et al.   PLoS One

Lack of XBP-1 Impedes Murine Cytomegalovirus Gene Expression

(2014) Adi Drori et al.   PLoS One

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

(2014) M. Lu et al.   SCIENCE

Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration

(2014) Risheng Ye et al.   eLife

Increased Expression of Endoplasmic Reticulum Stress and Unfolded Protein Response Genes in Peripheral Blood Mononuclear Cells From Patients With Limited Cutaneous Systemic Sclerosis and Pulmonary Arterial Hypertension

(2013) Stefania Lenna et al.   ARTHRITIS AND RHEUMATISM

Targeting endoplasmic reticulum stress in metabolic disease

(2013) Stewart Siyan Cao et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Unfolded Protein Response and Chemical Chaperones Reduce Protein Misfolding and Colitis in Mice

(2013) Stewart Siyan Cao et al.   GASTROENTEROLOGY

Oligodendrocyte-Specific Activation of PERK Signaling Protects Mice against Experimental Autoimmune Encephalomyelitis

(2013) W. Lin et al.   JOURNAL OF NEUROSCIENCE

Leptin signaling and leptin resistance

(2013) Yingjiang Zhou et al.   Frontiers of Medicine

Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling

(2012) Song Ling et al.   ARTHRITIS AND RHEUMATISM

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

Unfolded protein response

(2012) Stewart Siyan Cao et al.   CURRENT BIOLOGY

PKR protects colonic epithelium against colitis through the unfolded protein response and prosurvival signaling

(2012) Stewart Siyan Cao et al.   INFLAMMATORY BOWEL DISEASES

PKR in DSS-induced Colitis

(2012) Stewart Siyan Cao et al.   INFLAMMATORY BOWEL DISEASES

Hypothalamic dysfunction in obesity

(2012) Lynda M. Williams   PROCEEDINGS OF THE NUTRITION SOCIETY

Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein Elicits Antigen-Specific Tumor Immunity

(2011) Yasuaki Tamura et al.   JOURNAL OF IMMUNOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells

(2010) Joanna M. Tarr et al.   ARTHRITIS AND RHEUMATISM

Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis

(2010) Arthur Kaser et al.   CURRENT OPINION IN GASTROENTEROLOGY

LKM-1 Sera from Autoimmune Hepatitis Patients that Recognize ERp57, Carboxylesterase 1 and CYP2D6

(2010) Ryo Komurasaki et al.   Drug Metabolism and Pharmacokinetics

The Endoplasmic Reticulum Stress-Inducible Protein, Herp, Is a Potential Triggering Antigen for Anti-DNA Response

(2010) Y. Hirabayashi et al.   JOURNAL OF IMMUNOLOGY

Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis

(2010) S. Byrne et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Antibodies to the endoplasmic reticulum-resident chaperones calnexin, BiP and Grp94 in patients with rheumatoid arthritis and systemic lupus erythematosus

(2010) C. K. Weber et al.   RHEUMATOLOGY

Innate immunity and adipose tissue biology

(2010) Andreas Schäffler et al.   TRENDS IN IMMUNOLOGY

IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKβ and ER Stress Inhibition

(2010) Eduardo R. Ropelle et al.   PLOS BIOLOGY

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

(2009) C. Hetz et al.   GENES & DEVELOPMENT

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

(2009) Smita Saxena et al.   NATURE NEUROSCIENCE

Candidate autoantigens identified by mass spectrometry in early rheumatoid arthritis are chaperones and citrullinated glycolytic enzymes

(2009) Vincent Goëb et al.   ARTHRITIS RESEARCH & THERAPY

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

(2008) H. Nishitoh et al.   GENES & DEVELOPMENT

Nitrated Alpha-Synuclein and Microglial Neuroregulatory Activities

(2008) Ashley D. Reynolds et al.   Journal of Neuroimmune Pharmacology

Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

(2008) Julie D. Atkin et al.   NEUROBIOLOGY OF DISEASE

Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons

(2008) Eric J. Benner et al.   PLoS One