Metastasis in context: modeling the tumor microenvironment with cancer-on-a-chip approaches
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metastasis in context: modeling the tumor microenvironment with cancer-on-a-chip approaches
Authors
Keywords
-
Journal
Disease Models & Mechanisms
Volume 11, Issue 3, Pages dmm033100
Publisher
The Company of Biologists
Online
2018-03-16
DOI
10.1242/dmm.033100
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Remodeling the Tumor Microenvironment with Emerging Nanotherapeutics
- (2018) Qin Chen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Cancer associated fibroblasts: An essential role in the tumor microenvironment
- (2017) Leilei Tao et al. Oncology Letters
- Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro
- (2017) Bryan A. Hassell et al. Cell Reports
- Characterization of three-dimensional cancer cell migration in mixed collagen-Matrigel scaffolds using microfluidics and image analysis
- (2017) María Anguiano et al. PLoS One
- 3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells
- (2017) Stefania Parlato et al. Scientific Reports
- The hypoxic tumor microenvironment: A driving force for breast cancer progression
- (2016) Gregg L. Semenza BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Reverse Engineering Human Pathophysiology with Organs-on-Chips
- (2016) Donald E. Ingber CELL
- Fibroblast activation in cancer: when seed fertilizes soil
- (2016) Sanya-Eduarda Kuzet et al. CELL AND TISSUE RESEARCH
- Tumor-associated macrophages and anti-tumor therapies: complex links
- (2016) Cristina Belgiovine et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin
- (2016) Alexandra S. Piotrowski-Daspit et al. Integrative Biology
- Microengineered cancer-on-a-chip platforms to study the metastatic microenvironment
- (2016) R. Portillo-Lara et al. LAB ON A CHIP
- Oriented collagen fibers direct tumor cell intravasation
- (2016) Weijing Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device
- (2016) Ting Yu et al. Oncotarget
- Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment
- (2016) Danh Truong et al. Scientific Reports
- An Engineered Breast Cancer Model on a Chip to Replicate ECM-Activation In Vitro during Tumor Progression
- (2016) Filomena Gioiella et al. Advanced Healthcare Materials
- Biomimetic on-a-chip platforms for studying cancer metastasis
- (2016) Esak Lee et al. Current Opinion in Chemical Engineering
- Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density
- (2016) Kellie S. Gross et al. PLoS One
- Development and characterization of a microfluidic model of the tumour microenvironment
- (2016) Jose M. Ayuso et al. Scientific Reports
- Microfluidic model of ductal carcinoma in situ with 3D, organotypic structure
- (2015) Lauren L Bischel et al. BMC CANCER
- Tumor-associated macrophages in cancers
- (2015) W. Hu et al. Clinical & Translational Oncology
- An in vitro model of the tumor–lymphatic microenvironment with simultaneous transendothelial and luminal flows reveals mechanisms of flow enhanced invasion
- (2015) M. Pisano et al. Integrative Biology
- Interstitial flows promote amoeboid over mesenchymal motility of breast cancer cells revealed by a three dimensional microfluidic model
- (2015) Yu Ling Huang et al. Integrative Biology
- The interaction of anticancer therapies with tumor-associated macrophages
- (2015) Alberto Mantovani et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells
- (2015) Xue-Ying Wang et al. LAB ON A CHIP
- A microengineered pathophysiological model of early-stage breast cancer
- (2015) Yoonseok Choi et al. LAB ON A CHIP
- Investigation into the hypoxia-dependent cytotoxicity of anticancer drugs under oxygen gradient in a microfluidic device
- (2015) Zonghua Wang et al. Microfluidics and Nanofluidics
- Macrophages and cancer: from mechanisms to therapeutic implications
- (2015) Renato Ostuni et al. TRENDS IN IMMUNOLOGY
- Bladder cancer cells re-educate TAMs through lactate shuttling in the microfluidic cancer microenvironment
- (2015) Yang Zhao et al. Oncotarget
- Contact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and β2 integrin interactions
- (2015) Jing Bai et al. Oncotarget
- Lessons from patient-derived xenografts for better in vitro modeling of human cancer
- (2014) Stephen Yiu Chuen Choi et al. ADVANCED DRUG DELIVERY REVIEWS
- Bioengineering 3D environments for cancer models
- (2014) Mireia Alemany-Ribes et al. ADVANCED DRUG DELIVERY REVIEWS
- The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer
- (2014) Britta Weigelt et al. ADVANCED DRUG DELIVERY REVIEWS
- A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation
- (2014) Hyunjae Lee et al. Biomicrofluidics
- A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia
- (2014) Miguel A. Acosta et al. Biomicrofluidics
- Angiocrine Factors Deployed by Tumor Vascular Niche Induce B Cell Lymphoma Invasiveness and Chemoresistance
- (2014) Zhongwei Cao et al. CANCER CELL
- Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform
- (2014) Andrew D. Wong et al. CANCER RESEARCH
- Intratumoral phenotypic heterogeneity as an encourager of cancer invasion
- (2014) Yoojin Shin et al. Integrative Biology
- A polydimethylsiloxane–polycarbonate hybrid microfluidic device capable of generating perpendicular chemical and oxygen gradients for cell culture studies
- (2014) Chia-Wen Chang et al. LAB ON A CHIP
- Endothelial Cells Provide a Notch-Dependent Pro-Tumoral Niche for Enhancing Breast Cancer Survival, Stemness and Pro-Metastatic Properties
- (2014) Pegah Ghiabi et al. PLoS One
- Mechanotransduction of fluid stresses governs 3D cell migration
- (2014) W. J. Polacheck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation
- (2014) Jessie S. Jeon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Peritumoral interstitial fluid flow velocity predicts survival in cervical carcinoma
- (2014) Tord Hompland et al. RADIOTHERAPY AND ONCOLOGY
- A microfabricated platform for establishing oxygen gradients in 3-D constructs
- (2013) Shawn C. Oppegard et al. BIOMEDICAL MICRODEVICES
- Acidic extracellular microenvironment and cancer
- (2013) Yasumasa Kato et al. Cancer Cell International
- Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment
- (2013) E. M. Dijkgraaf et al. CANCER RESEARCH
- LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis
- (2013) T. R. Cox et al. CANCER RESEARCH
- Acidity Generated by the Tumor Microenvironment Drives Local Invasion
- (2013) V. Estrella et al. CANCER RESEARCH
- A bioengineered heterotypic stroma–cancer microenvironment model to study pancreatic ductal adenocarcinoma
- (2013) Cole R. Drifka et al. LAB ON A CHIP
- Interaction between lung cancer cell and myofibroblast influenced by cyclic tensile strain
- (2013) Jiun-Wei Huang et al. LAB ON A CHIP
- Probing the role of mesenchymal stem cells in salivary gland cancer on biomimetic microdevices
- (2012) Huipeng Ma et al. Integrative Biology
- The extracellular matrix: A dynamic niche in cancer progression
- (2012) Pengfei Lu et al. JOURNAL OF CELL BIOLOGY
- A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment
- (2012) Kenichi Funamoto et al. LAB ON A CHIP
- Construction of oxygen and chemical concentration gradients in a single microfluidic device for studying tumor cell–drug interactions in a dynamic hypoxia microenvironment
- (2012) Lei Wang et al. LAB ON A CHIP
- A three-dimensional microfluidic tumor cell migration assay to screen the effect of anti-migratory drugs and interstitial flow
- (2012) Johann Kalchman et al. Microfluidics and Nanofluidics
- Matrix rigidity regulates a switch between TGF-β1–induced apoptosis and epithelial–mesenchymal transition
- (2012) Jennifer L. Leight et al. MOLECULAR BIOLOGY OF THE CELL
- Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis and metastasis
- (2012) G L Semenza ONCOGENE
- Modulation of Invasive Phenotype by Interstitial Pressure-Driven Convection in Aggregates of Human Breast Cancer Cells
- (2012) Joe Tien et al. PLoS One
- Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function
- (2012) I. K. Zervantonakis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Fluid Mechanics of Cancer and Its Therapy
- (2011) Petros Koumoutsakos et al. Annual Review of Fluid Mechanics
- Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
- (2011) Paolo Cirri et al. CANCER AND METASTASIS REVIEWS
- HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF
- (2011) Charlotte Rolny et al. CANCER CELL
- Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
- (2011) Peter Friedl et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Effects of respiratory mechanical forces on the pharmacological response of lung cancer cells to chemotherapeutic agents
- (2011) Peter Hendricks et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber
- (2011) Ulrike Haessler et al. Integrative Biology
- Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release
- (2011) Kristina Goetze INTERNATIONAL JOURNAL OF ONCOLOGY
- Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions
- (2011) Yung-Ann Chen et al. LAB ON A CHIP
- Analysis of the paracrine loop between cancer cells and fibroblasts using a microfluidic chip
- (2011) Tsi-Hsuan Hsu et al. LAB ON A CHIP
- Initial steps of metastasis: Cell invasion and endothelial transmigration
- (2011) Franziska van Zijl et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Interstitial flow influences direction of tumor cell migration through competing mechanisms
- (2011) W. J. Polacheck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic interplay between the collagen scaffold and tumor evolution
- (2010) Mikala Egeblad et al. CURRENT OPINION IN CELL BIOLOGY
- Macrophages, innate immunity and cancer: balance, tolerance, and diversity
- (2010) Alberto Mantovani et al. CURRENT OPINION IN IMMUNOLOGY
- Characterization of the interaction between fibroblasts and tumor cells on a microfluidic co-culture device
- (2010) Huipeng Ma et al. ELECTROPHORESIS
- Activation of fibroblasts in cancer stroma
- (2010) Kati Räsänen et al. EXPERIMENTAL CELL RESEARCH
- Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages
- (2010) Ilia N. Buhtoiarov et al. IMMUNOLOGY
- Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects
- (2010) Kyung Eun Sung et al. Integrative Biology
- The extracellular matrix at a glance
- (2010) C. Frantz et al. JOURNAL OF CELL SCIENCE
- Heterogeneity of the Tumor Vasculature
- (2010) Janice Nagy et al. SEMINARS IN THROMBOSIS AND HEMOSTASIS
- Mechanics, malignancy, and metastasis: The force journey of a tumor cell
- (2009) Sanjay Kumar et al. CANCER AND METASTASIS REVIEWS
- Engineering microscale cellular niches for three-dimensional multicellular co-cultures
- (2009) Carlos P. Huang et al. LAB ON A CHIP
- The Extracellular Matrix: Not Just Pretty Fibrils
- (2009) R. O. Hynes SCIENCE
- Origin and function of tumor stroma fibroblasts
- (2009) Georgia Xouri et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression
- (2009) Masayuki Shimoda et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Tube Travel: The Role of Proteases in Individual and Collective Cancer Cell Invasion
- (2008) P. Friedl et al. CANCER RESEARCH
- Mechanical factors activate ß‐catenin‐dependent oncogene expression in APC1638N/+ mouse colon
- (2008) Joanne Whitehead et al. HFSP Journal
- A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics
- (2008) Colin L. Walsh et al. LAB ON A CHIP
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
- Macrophage polarization in tumour progression
- (2008) Antonio Sica et al. SEMINARS IN CANCER BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More