An in vitro model of the tumor–lymphatic microenvironment with simultaneous transendothelial and luminal flows reveals mechanisms of flow enhanced invasion

Steady-State Antigen Scavenging, Cross-Presentation, and CD8+ T Cell Priming: A New Role for Lymphatic Endothelial Cells

(2014) S. Hirosue et al.   JOURNAL OF IMMUNOLOGY

Microfluidic culture models to study the hydrodynamics of tumor progression and therapeutic response

(2013) Cara Buchanan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Lymphatics as a New Active Player in Reverse Cholesterol Transport

(2013) Mark L. Kahn et al.   Cell Metabolism

Mechanisms of tumor cell extravasation in an in vitro microvascular network platform

(2013) Michelle B. Chen et al.   Integrative Biology

A contact line pinning based microfluidic platform for modelling physiological flows

(2013) Chih-kuan Tung et al.   LAB ON A CHIP

In Vitro Model of Tumor Cell Extravasation

(2013) Jessie S. Jeon et al.   PLoS One

Inhibition of VEGF-C Modulates Distal Lymphatic Remodeling and Secondary Metastasis

(2013) Alvin Gogineni et al.   PLoS One

Microfluidic Models of Vascular Functions

(2012) Keith H.K. Wong et al.   Annual Review of Biomedical Engineering

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

(2012) E. F. Tewalt et al.   BLOOD

Pivotal roles of shear stress in the microenvironmental changes that occur within sentinel lymph nodes

(2012) Yoshiko Kawai et al.   CANCER SCIENCE

Microfluidics for in vitro biomimetic shear stress-dependent leukocyte adhesion assays

(2012) Elena Bianchi et al.   JOURNAL OF BIOMECHANICS

Interstitial Fluid and Lymph Formation and Transport: Physiological Regulation and Roles in Inflammation and Cancer

(2012) Helge Wiig et al.   PHYSIOLOGICAL REVIEWS

VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics

(2012) Amanda W. Lund et al.   Cell Reports

Role of the lymphatics in cancer metastasis and chemotherapy applications

(2011) Jennifer D. McAllaster et al.   ADVANCED DRUG DELIVERY REVIEWS

The Fluid Mechanics of Cancer and Its Therapy

(2011) Petros Koumoutsakos et al.   Annual Review of Fluid Mechanics

Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber

(2011) Ulrike Haessler et al.   Integrative Biology

New Molecular Mechanisms for Cardiovascular Disease: Blood Flow Sensing Mechanism in Vascular Endothelial Cells

(2011) Kimiko Yamamoto et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Integration of intra- and extravasation in one cell-based microfluidic chip for the study of cancer metastasis

(2011) Min Kyeong Shin et al.   LAB ON A CHIP

Nitric oxide (NO) side of lymphatic flow and immune surveillance

(2011) G. W. Schmid-Schonbein   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interstitial flow influences direction of tumor cell migration through competing mechanisms

(2011) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanotransduction of shear in the endothelium: Basic studies and clinical implications

(2011) Blair D Johnson et al.   VASCULAR MEDICINE

Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium

(2010) Dimana O. Miteva et al.   CIRCULATION RESEARCH

Lymphatic Endothelial Cells Adapt Their Barrier Function in Response to Changes in Shear Stress

(2010) Jerome W. Breslin et al.   Lymphatic Research and Biology

Direct, real-time measurement of shear stress-induced nitric oxide produced from endothelial cells in vitro

(2010) Allison M. Andrews et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Shear stress-induced ATP-mediated endothelial constitutive nitric oxide synthase expression in human lymphatic endothelial cells

(2009) Yoshiko Kawai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Assays for Eukaryotic Cell Chemotaxis

(2009) Zac Pujic et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Tumor metastasis and the lymphatic vasculature

(2009) Jonathan P. Sleeman et al.   INTERNATIONAL JOURNAL OF CANCER

Hydrodynamic Shear Rate Regulates Melanoma-Leukocyte Aggregation, Melanoma Adhesion to the Endothelium, and Subsequent Extravasation

(2008) Shile Liang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Cell migration into scaffolds under co-culture conditions in a microfluidic platform

(2008) Seok Chung et al.   LAB ON A CHIP