A bioengineered heterotypic stroma–cancer microenvironment model to study pancreatic ductal adenocarcinoma
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Title
A bioengineered heterotypic stroma–cancer microenvironment model to study pancreatic ductal adenocarcinoma
Authors
Keywords
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Journal
LAB ON A CHIP
Volume 13, Issue 19, Pages 3965
Publisher
Royal Society of Chemistry (RSC)
Online
2013-07-31
DOI
10.1039/c3lc50487e
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Note: Only part of the references are listed.- Engineering fibrotic tissue in pancreatic cancer: A novel three-dimensional model to investigate nanoparticle delivery
- (2012) Hitomi Hosoya et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2012) Isabelle Dufau et al. BMC CANCER
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- Imaging Tumor-Stroma Interactions during Chemotherapy Reveals Contributions of the Microenvironment to Resistance
- (2012) Elizabeth S. Nakasone et al. CANCER CELL
- In vivo biomarker expression patterns are preserved in 3D cultures of Prostate Cancer
- (2012) Louisa C.E. Windus et al. EXPERIMENTAL CELL RESEARCH
- What We Have Learned About Pancreatic Cancer From Mouse Models
- (2012) Pedro A. Pérez–Mancera et al. GASTROENTEROLOGY
- Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
- (2012) Michael A Jacobetz et al. GUT
- Hedgehog signaling in myofibroblasts directly promotes prostate tumor cell growth
- (2012) Maribella Domenech et al. Integrative Biology
- Patient-derived tumour xenografts as models for oncology drug development
- (2012) John J. Tentler et al. Nature Reviews Clinical Oncology
- The role of stroma in pancreatic cancer: diagnostic and therapeutic implications
- (2012) Mert Erkan et al. Nature Reviews Gastroenterology & Hepatology
- Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
- (2012) T. Stylianopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Desmoplasia in Pancreatic Cancer. Can We Fight It?
- (2012) E. E. Merika et al. Gastroenterology Research and Practice
- Overcoming the stromal barrier: technologies to optimize drug delivery in pancreatic cancer
- (2012) Anastasios Dimou et al. Therapeutic Advances in Medical Oncology
- Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
- (2011) Matthew W. Conklin et al. AMERICAN JOURNAL OF PATHOLOGY
- Microfluidic cell coculture methods for understanding cell biology, analyzing bio/pharmaceuticals, and developing tissue constructs
- (2011) Mohana Marimuthu et al. ANALYTICAL BIOCHEMISTRY
- Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression
- (2011) Mario A. Shields et al. BIOCHEMICAL JOURNAL
- FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
- (2011) Hyung-Ok Lee et al. BMC CANCER
- A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells
- (2011) Lorenzo F. Sempere et al. CANCER BIOLOGY & THERAPY
- Pancreatic Stellate Cells Radioprotect Pancreatic Cancer Cells through 1-Integrin Signaling
- (2011) T. S. Mantoni et al. CANCER RESEARCH
- StellaTUM: current consensus and discussion on pancreatic stellate cell research
- (2011) Mert Erkan et al. GUT
- Gemcitabine Plusnab-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial
- (2011) Daniel D. Von Hoff et al. JOURNAL OF CLINICAL ONCOLOGY
- Morphological and cytoskeletal changes of pancreatic cancer cells in three-dimensional spheroidal culture
- (2011) Yoko Matsuda et al. Medical Molecular Morphology
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of the Human Pancreatic Stellate Cell Secreted Proteome
- (2011) Angela Y. Wehr et al. PANCREAS
- Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors
- (2011) B. Diop-Frimpong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
- (2011) G. L. Beatty et al. SCIENCE
- Genexol inhibits primary tumour growth and metastases in gemcitabine-resistant pancreatic ductal adenocarcinoma
- (2011) Jill E. Shea et al. HPB
- Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells
- (2010) Daniela Loessner et al. BIOMATERIALS
- Alterations of the extracellular matrix in ovarian cancer studied by Second Harmonic Generation imaging microscopy
- (2010) Oleg Nadiarnykh et al. BMC CANCER
- Three-Dimensional Collagen I Promotes Gemcitabine Resistance in Pancreatic Cancer through MT1-MMP-Mediated Expression of HMGA2
- (2010) S. Dangi-Garimella et al. CANCER RESEARCH
- Fundamentals of microfluidic cell culture in controlled microenvironments
- (2010) Edmond W. K. Young et al. CHEMICAL SOCIETY REVIEWS
- Overexpression of Smoothened Activates the Sonic Hedgehog Signaling Pathway in Pancreatic Cancer-Associated Fibroblasts
- (2010) K. Walter et al. CLINICAL CANCER RESEARCH
- Dynamic interplay between the collagen scaffold and tumor evolution
- (2010) Mikala Egeblad et al. CURRENT OPINION IN CELL BIOLOGY
- Tumors on chips: oncology meets microfluidics
- (2010) Donald Wlodkowic et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Stromal biology and therapy in pancreatic cancer
- (2010) A. Neesse et al. GUT
- Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects
- (2010) Kyung Eun Sung et al. Integrative Biology
- Stromal Depletion Goes on Trial in Pancreatic Cancer
- (2010) K. Garber JNCI-Journal of the National Cancer Institute
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- (2010) Tingjiao Liu et al. LAB ON A CHIP
- Organ-, inflammation- and cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells
- (2010) Mert Erkan et al. Molecular Cancer
- Pancreatic Cancer
- (2010) Manuel Hidalgo NEW ENGLAND JOURNAL OF MEDICINE
- Phenotype and Genotype of Pancreatic Cancer Cell Lines
- (2010) Emily L. Deer et al. PANCREAS
- Organotypic Culture Model of Pancreatic Cancer Demonstrates that Stromal Cells Modulate E-Cadherin, β-Catenin, and Ezrin Expression in Tumor Cells
- (2009) Fieke E.M. Froeling et al. AMERICAN JOURNAL OF PATHOLOGY
- Control of 3-dimensional collagen matrix polymerization for reproducible human mammary fibroblast cell culture in microfluidic devices
- (2009) Kyung Eun Sung et al. BIOMATERIALS
- Tumor-stromal interactions with direct cell contacts enhance proliferation of human pancreatic carcinoma cells
- (2009) Hayato Fujita et al. CANCER SCIENCE
- In vitromodels of pancreatic cancer for translational oncology research
- (2009) Georg Feldmann et al. Expert Opinion on Drug Discovery
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- (2009) Sung Pil Hong et al. INTERNATIONAL JOURNAL OF CANCER
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- (2009) Atsushi Masamune et al. JOURNAL OF GASTROENTEROLOGY
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- (2009) S.T. Kreger et al. MATRIX BIOLOGY
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- (2009) Eduard Ryschich et al. PANCREAS
- Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
- (2009) H. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Breaching the Cancer Fortress
- (2009) P. Olson et al. SCIENCE
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- (2009) K. P. Olive et al. SCIENCE
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- (2009) Paolo P. Provenzano et al. TRENDS IN CELL BIOLOGY
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- Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression
- (2008) R. F. Hwang et al. CANCER RESEARCH
- Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer
- (2008) J. M. Bailey et al. CLINICAL CANCER RESEARCH
- Enhanced macromolecule diffusion deep in tumors after enzymatic digestion of extracellular matrix collagen and its associated proteoglycan decorin
- (2007) Mazin Magzoub et al. FASEB JOURNAL
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