Mechanotransduction of fluid stresses governs 3D cell migration

Coevolution of Solid Stress and Interstitial Fluid Pressure in Tumors During Progression: Implications for Vascular Collapse

(2013) Triantafyllos Stylianopoulos et al.   CANCER RESEARCH

Paxillin controls directional cell motility in response to physical cues

(2013) Julia E. Sero et al.   Cell Adhesion & Migration

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

Tumor cell migration in complex microenvironments

(2012) William J. Polacheck et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanism of a flow-gated angiogenesis switch: early signaling events at cell–matrix and cell–cell junctions

(2012) Vernella Vickerman et al.   Integrative Biology

2D protrusion but not motility predicts growth factor–induced cancer cell migration in 3D collagen

(2012) Aaron S. Meyer et al.   JOURNAL OF CELL BIOLOGY

Nonpolarized signaling reveals two distinct modes of 3D cell migration

(2012) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

In vitro formation and characterization of a perfusable three-dimensional tubular capillary network in microfluidic devices

(2012) Ju Hun Yeon et al.   LAB ON A CHIP

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

Ensemble Analysis of Angiogenic Growth in Three-Dimensional Microfluidic Cell Cultures

(2012) Waleed A. Farahat et al.   PLoS One

Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber

(2011) Ulrike Haessler et al.   Integrative Biology

Heparan Sulfate Proteoglycans Mediate Interstitial Flow Mechanotransduction Regulating MMP-13 Expression and Cell Motility via FAK-ERK in 3D Collagen

(2011) Zhong-Dong Shi et al.   PLoS One

Paxillin Mediates Sensing of Physical Cues and Regulates Directional Cell Motility by Controlling Lamellipodia Positioning

(2011) Julia E. Sero et al.   PLoS One

Interstitial flow influences direction of tumor cell migration through competing mechanisms

(2011) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery of Molecular and Nanoscale Medicine to Tumors: Transport Barriers and Strategies

(2011) Vikash P. Chauhan et al.   Annual Review of Chemical and Biomolecular Engineering

Stretchy Proteins on Stretchy Substrates: The Important Elements of Integrin-Mediated Rigidity Sensing

(2010) Simon W. Moore et al.   DEVELOPMENTAL CELL

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Cells in 3D matrices under interstitial flow: Effects of extracellular matrix alignment on cell shear stress and drag forces

(2009) John A. Pedersen et al.   JOURNAL OF BIOMECHANICS

FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion

(2009) Keefe T. Chan et al.   JOURNAL OF CELL BIOLOGY

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Formation of Human Capillaries In Vitro: The Engineering of Prevascularized Matrices

(2009) Irene Montaño et al.   TISSUE ENGINEERING PART A

Cell Stiffening in Response to External Stress is Correlated to Actin Recruitment

(2008) Delphine Icard-Arcizet et al.   BIOPHYSICAL JOURNAL

Cell-Cell Mechanical Communication through Compliant Substrates

(2008) Cynthia A. Reinhart-King et al.   BIOPHYSICAL JOURNAL

Spatiotemporal Analysis of Cell Response to a Rigidity Gradient: A Quantitative Study Using Multiple Optical Tweezers

(2008) Myriam Allioux-Guérin et al.   BIOPHYSICAL JOURNAL

Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

(2008) Colin K. Choi et al.   NATURE CELL BIOLOGY