Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro

Title
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro
Authors
Keywords
lung cancer, microfluidic, organ-on-chip, invasion, persister cell, tyrosine kinase inhibitor, EGFR inhibitor, mechanical, chemotherapy, mechanobiology
Journal
Cell Reports
Volume 21, Issue 2, Pages 508-516
Publisher
Elsevier BV
Online
2017-10-13
DOI
10.1016/j.celrep.2017.09.043

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