Interstitial flows promote amoeboid over mesenchymal motility of breast cancer cells revealed by a three dimensional microfluidic model

Modeling Tumor Microenvironments In Vitro

(2014) Mingming Wu et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Mechanotransduction of fluid stresses governs 3D cell migration

(2014) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional cell migration does not follow a random walk

(2014) P.-H. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interstitial fluid flow in cancer: implications for disease progression and treatment

(2014) Jennifer Munson et al.   Cancer Management and Research

Toward single cell traction microscopy within 3D collagen matrices

(2013) Matthew S. Hall et al.   EXPERIMENTAL CELL RESEARCH

A contact line pinning based microfluidic platform for modelling physiological flows

(2013) Chih-kuan Tung et al.   LAB ON A CHIP

Cooperative Roles of SDF-1α and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

(2013) Beum Jun Kim et al.   PLoS One

Targeting tumor cell motility as a strategy against invasion and metastasis

(2013) Alan Wells et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Interstitial Fluid Pressure and Associated Lymph Node Metastasis Revealed in Tumors by Dynamic Contrast-Enhanced MRI

(2012) T. Hompland et al.   CANCER RESEARCH

Interstitial Flow in a 3D Microenvironment Increases Glioma Invasion by a CXCR4-Dependent Mechanism

(2012) J. M. Munson et al.   CANCER RESEARCH

Nonpolarized signaling reveals two distinct modes of 3D cell migration

(2012) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

Measuring Traction Forces of Motile Dendritic Cells on Micropost Arrays

(2011) Brendon G. Ricart et al.   BIOPHYSICAL JOURNAL

Tumor Cell Invasion Is Promoted by Interstitial Flow-Induced Matrix Priming by Stromal Fibroblasts

(2011) A. C. Shieh et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness

(2011) Amit Pathak et al.   Integrative Biology

Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber

(2011) Ulrike Haessler et al.   Integrative Biology

Phaseguides: a paradigm shift in microfluidic priming and emptying

(2011) Paul Vulto et al.   LAB ON A CHIP

Interstitial flow influences direction of tumor cell migration through competing mechanisms

(2011) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro

(2010) Valerie L. Cross et al.   BIOMATERIALS

Transcapillary exchange: role and importance of the interstitial fluid pressure and the extracellular matrix

(2010) Rolf K. Reed et al.   CARDIOVASCULAR RESEARCH

Mechanisms of force generation and force transmission during interstitial leukocyte migration

(2010) Jörg Renkawitz et al.   EMBO REPORTS

Critical review: cellular mechanobiology and amoeboid migration

(2010) Jochen Guck et al.   Integrative Biology

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Probing cellular mechanobiology in three-dimensional culture with collagen–agarose matrices

(2009) Theresa A. Ulrich et al.   BIOMATERIALS

Multiscale Measurements Distinguish Cellular and Interstitial Hindrances to Diffusion In Vivo

(2009) Vikash P. Chauhan et al.   BIOPHYSICAL JOURNAL

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Clinical Importance of Lymph Node Density in Predicting Outcome of Prostate Cancer Patients

(2009) Tommaso Cai et al.   JOURNAL OF SURGICAL RESEARCH

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates

(2009) D Yamazaki et al.   ONCOGENE

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Imaging amoeboid cancer cell motilityin vivo

(2008) S. PINNER et al.   JOURNAL OF MICROSCOPY

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE

Image Correlation Spectroscopy of Multiphoton Images Correlates with Collagen Mechanical Properties

(2007) Christopher B. Raub et al.   BIOPHYSICAL JOURNAL