In Vitro Microfluidic Models for Neurodegenerative Disorders

In vitro models of axon regeneration

(2017) Hassan Al-Ali et al.   EXPERIMENTAL NEUROLOGY

A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood–brain barrier

(2017) Giulia Adriani et al.   LAB ON A CHIP

On-chip human microvasculature assay for visualization and quantification of tumor cell extravasation dynamics

(2017) Michelle B Chen et al.   Nature Protocols

RETRACTED: In Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling

(2017) Kohei Yamamizu et al.   Stem Cell Reports

Neuron-Glia Interactions as Therapeutic Targets in Neurodegeneration

(2017) Alla B. Salmina   JOURNAL OF ALZHEIMERS DISEASE

Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering

(2016) Janahan Arulmoli et al.   Acta Biomaterialia

Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening

(2016) Ying I. Wang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Elucidation of the Roles of Tumor Integrin  1 in the Extravasation Stage of the Metastasis Cascade

(2016) M. B. Chen et al.   CANCER RESEARCH

Functional Connectivity under Optogenetic Control Allows Modeling of Human Neuromuscular Disease

(2016) Julius A. Steinbeck et al.   Cell Stem Cell

Glial-endothelial crosstalk regulates blood–brain barrier function

(2016) Lara Cheslow et al.   CURRENT OPINION IN PHARMACOLOGY

Development-on-chip:in vitroneural tube patterning with a microfluidic device

(2016) Christopher J. Demers et al.   DEVELOPMENT

Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling

(2016) Aleksander Skardal et al.   DRUG DISCOVERY TODAY

Compartmental microfluidic system for studying muscle–neuron communication and neuromuscular junction maintenance

(2016) Ariel Ionescu et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

A hybrid microfluidic system for regulation of neural differentiation in induced pluripotent stem cells

(2016) Zahra Hesari et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells

(2016) Steven F. Merkel et al.   JOURNAL OF NEUROCHEMISTRY

Compartmentalized Microfluidic Platforms: The Unrivaled Breakthrough of In Vitro Tools for Neurobiological Research

(2016) Estrela Neto et al.   JOURNAL OF NEUROSCIENCE

One-photon and two-photon stimulation of neurons in a microfluidic culture system

(2016) Jae Myung Jang et al.   LAB ON A CHIP

3D printed nervous system on a chip

(2016) Blake N. Johnson et al.   LAB ON A CHIP

Organization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidic in Vitro Model of the Blood–Brain Barrier

(2016) Jack D. Wang et al.   MOLECULAR PHARMACEUTICS

Remote Magnetic Orientation of 3D Collagen Hydrogels for Directed Neuronal Regeneration

(2016) Merav Antman-Passig et al.   NANO LETTERS

A versatile lab-on-a-chip tool for modeling biological barriers

(2016) Fruzsina R. Walter et al.   SENSORS AND ACTUATORS B-CHEMICAL

Physiological maturation and drug responses of human induced pluripotent stem cell-derived cortical neuronal networks in long-term culture

(2016) A. Odawara et al.   Scientific Reports

Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units

(2016) S. G. M. Uzel et al.   Science Advances

Multi-analyte biosensor interface for real-time monitoring of 3D microtissue spheroids in hanging-drop networks

(2016) Patrick M. Misun et al.   Microsystems & Nanoengineering

Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

(2016) Anna Herland et al.   PLoS One

High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform

(2016) Nienke R. Wevers et al.   Scientific Reports

Engineering Controllable Architecture in Matrigel for 3D Cell Alignment

(2015) Jae Myung Jang et al.   ACS Applied Materials & Interfaces

Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology

(2015) Janelle Drouin-Ouellet et al.   ANNALS OF NEUROLOGY

Recapitulation of in vivo-like paracrine signals of human mesenchymal stem cells for functional neuronal differentiation of human neural stem cells in a 3D microfluidic system

(2015) Kisuk Yang et al.   BIOMATERIALS

Collagen-based brain microvasculature model in vitro using three-dimensional printed template

(2015) Jeong Ah Kim et al.   Biomicrofluidics

An optically transparent membrane supports shear stress studies in a three-dimensional microfluidic neurovascular unit model

(2015) Katelyn L. Sellgren et al.   Biomicrofluidics

Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor

(2015) Jacquelyn A. Brown et al.   Biomicrofluidics

Optogenetic stimulation of neuronal repair

(2015) Yan Xiao et al.   CURRENT BIOLOGY

Decellularization technology in CNS tissue repair

(2015) Hui Wang et al.   Expert Review of Neurotherapeutics

A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs

(2015) Choong Kim et al.   LAB ON A CHIP

Three-dimensional brain-on-a-chip with an interstitial level of flow and its application as an in vitro model of Alzheimer's disease

(2015) JiSoo Park et al.   LAB ON A CHIP

Ultrafast superresolution fluorescence imaging with spinning disk confocal microscope optics

(2015) Shinichi Hayashi et al.   MOLECULAR BIOLOGY OF THE CELL

A microfluidic device for label-free, physical capture of circulating tumor cell clusters

(2015) A Fatih Sarioglu et al.   NATURE METHODS

In vitro bioengineered model of cortical brain tissue

(2015) Karolina Chwalek et al.   Nature Protocols

A 3D human neural cell culture system for modeling Alzheimer's disease

(2015) Young Hye Kim et al.   Nature Protocols

Acetylation and phosphorylation of STAT3 are involved in the responsiveness of microglia to beta amyloid

(2015) Margherita Eufemi et al.   NEUROCHEMISTRY INTERNATIONAL

Glial Regulation of the Neuronal Connectome through Local and Long-Distant Communication

(2015) R. Douglas Fields et al.   NEURON

Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer

(2015) YOSHINORI IMAMURA et al.   ONCOLOGY REPORTS

Simultaneous or Sequential Orthogonal Gradient Formation in a 3D Cell Culture Microfluidic Platform

(2015) Sebastien G. M. Uzel et al.   Small

Microglia are crucial regulators of neuro-immunity during central nervous system tuberculosis

(2015) Jonathan Paul Spanos et al.   Frontiers in Cellular Neuroscience

Optogenetic control of contractile function in skeletal muscle

(2015) Tobias Bruegmann et al.   Nature Communications

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain

(2015) Shuko Takeda et al.   Nature Communications

Optogenetic induction of contractile ability in immature C2C12 myotubes

(2015) Toshifumi Asano et al.   Scientific Reports

Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology

(2015) Hansang Cho et al.   Scientific Reports

Engineering-Aligned 3D Neural Circuit in Microfluidic Device

(2015) Seokyoung Bang et al.   Advanced Healthcare Materials

Decellularization technology in CNS tissue repair

(2015) Hui Wang et al.   Expert Review of Neurotherapeutics

Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation

(2015) Melanie Greter et al.   Frontiers in Immunology

Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS

(2015) Francesca Navone et al.   Cells

Combining Microfluidics, Optogenetics and Calcium Imaging to Study Neuronal Communication In Vitro

(2015) Renaud Renault et al.   PLoS One

A Triple Culture Model of the Blood-Brain Barrier Using Porcine Brain Endothelial cells, Astrocytes and Pericytes

(2015) Louiza Bohn Thomsen et al.   PLoS One

A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip

(2015) Sudhir P. Deosarkar et al.   PLoS One

The neurovascular unit - concept review

(2014) V. Muoio et al.   Acta Physiologica

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Cell-Based Biosensors and Their Application in Biomedicine

(2014) Qingjun Liu et al.   CHEMICAL REVIEWS

How to make spinal motor neurons

(2014) B. N. Davis-Dusenbery et al.   DEVELOPMENT

Positive association of free triiodothyronine with pancreatic β-cell function in people with prediabetes

(2014) T. Oda et al.   DIABETIC MEDICINE

The glia/neuron ratio: How it varies uniformly across brain structures and species and what that means for brain physiology and evolution

(2014) Suzana Herculano-Houzel   GLIA

Sensory neurons and osteoblasts: close partners in a microfluidic platform

(2014) Estrela Neto et al.   Integrative Biology

Chemically induced synaptic activity between mixed primary hippocampal co-cultures in a microfluidic system

(2014) Graham Robertson et al.   Integrative Biology

Microfluidic perfusion culture chip providing different strengths of shear stress for analysis of vascular endothelial function

(2014) Koji Hattori et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Interleukin-1β induces an inflammatory response and the breakdown of the endothelial cell layer in an improved human THBMEC-based in vitro blood–brain barrier model

(2014) Josephine Labus et al.   JOURNAL OF NEUROSCIENCE METHODS

Gelatin-based hydrogel for vascular endothelial growth factor release in peripheral nerve tissue engineering

(2014) S. Gnavi et al.   Journal of Tissue Engineering and Regenerative Medicine

Hepatic organoids for microfluidic drug screening

(2014) Sam H. Au et al.   LAB ON A CHIP

The blood-brain barrier: Structure, function and therapeutic approaches to cross it

(2014) Marta Tajes et al.   MOLECULAR MEMBRANE BIOLOGY

Bioengineered 3D Brain Tumor Model To Elucidate the Effects of Matrix Stiffness on Glioblastoma Cell Behavior Using PEG-Based Hydrogels

(2014) Christine Wang et al.   MOLECULAR PHARMACEUTICS

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Extracellular matrices, artificial neural scaffolds and the promise of neural regeneration

(2014) Ramesh Grandhi et al.   Neural Regeneration Research

Human Astrocytes: Secretome Profiles of Cytokines and Chemokines

(2014) Sung S. Choi et al.   PLoS One

Fluid shear stress threshold regulates angiogenic sprouting

(2014) P. A. Galie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice

(2014) E. A. Winkler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation

(2014) Jessie S. Jeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice

(2014) J. B. Bryson et al.   SCIENCE

Reconfigurable microfluidic hanging drop network for multi-tissue interaction and analysis

(2014) Olivier Frey et al.   Nature Communications

Parkinson’s disease: animal models and dopaminergic cell vulnerability

(2014) Javier Blesa et al.   Frontiers in Neuroanatomy

Hydrogel microfluidics for the patterning of pluripotent stem cells

(2014) S. Cosson et al.   Scientific Reports

Reconstituting Vascular Microenvironment of Neural Stem Cell Niche in Three-Dimensional Extracellular Matrix

(2014) Yoojin Shin et al.   Advanced Healthcare Materials

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

(2014) Simon Dujardin et al.   Acta Neuropathologica Communications

β-Amyloid is transmitted via neuronal connections along axonal membranes

(2013) Ha-Lim Song et al.   ANNALS OF NEUROLOGY

Three-dimensional neuron–muscle constructs with neuromuscular junctions

(2013) Yuya Morimoto et al.   BIOMATERIALS

Electrospun gelatin scaffolds incorporating rat decellularized brain extracellular matrix for neural tissue engineering

(2013) Silvia Baiguera et al.   BIOMATERIALS

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles

(2013) P Joshi et al.   CELL DEATH AND DIFFERENTIATION

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

(2013) Justine D. Miller et al.   Cell Stem Cell

In vitro models of angiogenesis and vasculogenesis in fibrin gel

(2013) Kristen T. Morin et al.   EXPERIMENTAL CELL RESEARCH

Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS

(2013) Anja Kunze et al.   Integrative Biology

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

(2013) Kyung-Jin Jang et al.   Integrative Biology

Base structure consisting of an endothelialized vascular-tree network and hepatocytes for whole liver engineering

(2013) Nana Shirakigawa et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Microfluidic primary culture model of the lower motor neuron–neuromuscular junction circuit

(2013) Katherine A. Southam et al.   JOURNAL OF NEUROSCIENCE METHODS

Probing cell–cell communication with microfluidic devices

(2013) Feng Guo et al.   LAB ON A CHIP

Engineering of functional, perfusable 3D microvascular networks on a chip

(2013) Sudong Kim et al.   LAB ON A CHIP

Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion-Like Disorder?

(2013) C. Warren Olanow et al.   MOVEMENT DISORDERS

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

(2013) Jackson Sandoe et al.   NATURE NEUROSCIENCE

Pathophysiology of the brain extracellular matrix: a new target for remyelination

(2013) Lorraine W. Lau et al.   NATURE REVIEWS NEUROSCIENCE

In Vitro Perfused Human Capillary Networks

(2013) Monica L. Moya et al.   TISSUE ENGINEERING PART C-METHODS

Rotational separation of non-spherical bioparticles using I-shaped pillar arrays in a microfluidic device

(2013) Kerwin Kwek Zeming et al.   Nature Communications

A microengineered cell fusion approach with combined optical tweezers and microwell array technologies

(2013) Xiaolin Wang et al.   RSC Advances

Microfluidic Chemotaxis Platform for Differentiating the Roles of Soluble and Bound Amyloid-β on Microglial Accumulation

(2013) Hansang Cho et al.   Scientific Reports

Neurotoxic amyloid beta oligomeric assemblies recreated in microfluidic platform with interstitial level of slow flow

(2013) Yoon Jung Choi et al.   Scientific Reports

Comparison of Biocompatibility and Adsorption Properties of Different Plastics for Advanced Microfluidic Cell and Tissue Culture Models

(2012) Paul M. van Midwoud et al.   ANALYTICAL CHEMISTRY

Overflow Microfluidic Networks: Application to the Biochemical Analysis of Brain Cell Interactions in Complex Neuroinflammatory Scenarios

(2012) Fabio Bianco et al.   ANALYTICAL CHEMISTRY

Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport

(2012) Eric C. Freundt et al.   ANNALS OF NEUROLOGY

Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels

(2012) Lauren L. Bischel et al.   BIOMATERIALS

Matrigel, but not collagen I, maintains the differentiation capacity of muscle derived cellsin vitro

(2012) S Grefte et al.   Biomedical Materials

Reliable permeability assay system in a microfluidic device mimicking cerebral vasculatures

(2012) Ju Hun Yeon et al.   BIOMEDICAL MICRODEVICES

BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function

(2012) L. M. Griep et al.   BIOMEDICAL MICRODEVICES

Impaired blood–brain/spinal cord barrier in ALS patients

(2012) Svitlana Garbuzova-Davis et al.   BRAIN RESEARCH

Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes

(2012) The HD iPSC Consortium   Cell Stem Cell

Sympathetic neurons modulate the beat rate of pluripotent cell-derived cardiomyocytes in vitro

(2012) Akimasa Takeuchi et al.   Integrative Biology

Three-dimensional extracellular matrix-mediated neural stem cell differentiation in a microfluidic device

(2012) Sewoon Han et al.   LAB ON A CHIP

Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)

(2012) Ross Booth et al.   LAB ON A CHIP

SyM-BBB: a microfluidic blood brain barrier model

(2012) Balabhaskar Prabhakarpandian et al.   LAB ON A CHIP

A modular approach to create a neurovascular unit-on-a-chip

(2012) Anil Kumar H. Achyuta et al.   LAB ON A CHIP

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex

(2012) Gerard M J Beaudoin et al.   Nature Protocols

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity

(2012) Stefano Camnasio et al.   NEUROBIOLOGY OF DISEASE

Axon Myelination and Electrical Stimulation in a Microfluidic, Compartmentalized Cell Culture Platform

(2012) In Hong Yang et al.   NEUROMOLECULAR MEDICINE

Intercellular (Mis)communication in Neurodegenerative Disease

(2012) Gwenn A. Garden et al.   NEURON

End-Plate Acetylcholine Receptor: Structure, Mechanism, Pharmacology, and Disease

(2012) Steven M. Sine   PHYSIOLOGICAL REVIEWS

Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution

(2012) ZiQiu Tong et al.   PLoS One

Ensemble Analysis of Angiogenic Growth in Three-Dimensional Microfluidic Cell Cultures

(2012) Waleed A. Farahat et al.   PLoS One

Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells

(2012) N. Egawa et al.   Science Translational Medicine

Microfluidic Investigation of BDNF-Enhanced Neural Stem Cell Chemotaxis in CXCL12 Gradients

(2012) Hui Xu et al.   Small

A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines

(2012) Jose Miguel Rubio-Perez et al.   TheScientificWorldJOURNAL

Microfluidic 3D cell culture: potential application for tissue-based bioassays

(2012) XiuJun (James) Li et al.   Bioanalysis

Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells

(2012) Takamichi Miyazaki et al.   Nature Communications

Microglia Function in Alzheimer’s Disease

(2012) Egle Solito et al.   Frontiers in Pharmacology

Microfluidic Transendothelial Electrical Resistance Measurement Device that Enables Blood Flow and Postgrowth Experiments

(2011) Paul A. Vogel et al.   ANALYTICAL CHEMISTRY

Sprouting Angiogenesis under a Chemical Gradient Regulated by Interactions with an Endothelial Monolayer in a Microfluidic Platform

(2011) Gi Seok Jeong et al.   ANALYTICAL CHEMISTRY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments

(2011) Ioannis K. Zervantonakis et al.   Biomicrofluidics

Blood-neural barrier: its diversity and coordinated cell-to-cell communication

(2011) Yoon-Kyung Choi et al.   BMB Reports

SnapShot: Spinal Cord Development

(2011) William A. Alaynick et al.   CELL

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

(2011) Esther Y. Son et al.   Cell Stem Cell

How many neurons do you have? Some dogmas of quantitative neuroscience under revision

(2011) Roberto Lent et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Modeling familial Alzheimer's disease with induced pluripotent stem cells

(2011) Takuya Yagi et al.   HUMAN MOLECULAR GENETICS

In Vitro Blood–Brain Barrier Models: Current and Perspective Technologies

(2011) Pooja Naik et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Phaseguides: a paradigm shift in microfluidic priming and emptying

(2011) Paul Vulto et al.   LAB ON A CHIP

In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients

(2011) Yoojin Shin et al.   LAB ON A CHIP

Axon diodes for the reconstruction of oriented neuronal networks in microfluidic chambers

(2011) Jean-Michel Peyrin et al.   LAB ON A CHIP

Meniscus induced self organization of multiple deep concave wells in a microchannel for embryoid bodies generation

(2011) Gi Seok Jeong et al.   LAB ON A CHIP

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Central nervous system pericytes in health and disease

(2011) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Cerebrovascular disorders: molecular insights and therapeutic opportunities

(2011) Erik Storkebaum et al.   NATURE NEUROSCIENCE

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Imaging Voltage in Neurons

(2011) Darcy S. Peterka et al.   NEURON

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Combination of Hyaluronic Acid Hydrogel Scaffold and PLGA Microspheres for Supporting Survival of Neural Stem Cells

(2011) Ying Wang et al.   PHARMACEUTICAL RESEARCH

Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites

(2011) M. S. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluid forces control endothelial sprouting

(2011) J. W. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decellularized Porcine Brain Matrix for Cell Culture and Tissue Engineering Scaffolds

(2011) Jessica A. DeQuach et al.   TISSUE ENGINEERING PART A

Microfluidic Platforms for Studies of Angiogenesis, Cell Migration, and Cell–Cell Interactions

(2010) Seok Chung et al.   ANNALS OF BIOMEDICAL ENGINEERING

Micropatterning neural cell cultures in 3D with a multi-layered scaffold

(2010) Anja Kunze et al.   BIOMATERIALS

Endothelial cell behaviour within a microfluidic mimic of the flow channels of a modular tissue engineered construct

(2010) Omar F. Khan et al.   BIOMEDICAL MICRODEVICES

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

Mutant Huntingtin in Glial Cells Exacerbates Neurological Symptoms of Huntington Disease Mice

(2010) Jennifer Bradford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronic acid hydrogel modified with nogo-66 receptor antibody and poly-L-lysine to promote axon regrowth after spinal cord injury

(2010) Yue-Teng Wei et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

An integrated microfluidic system for studying cell-microenvironmental interactions versatilely and dynamically

(2010) Wenming Liu et al.   LAB ON A CHIP

Guiding neuron development with planar surface gradients of substrate cues deposited using microfluidic devices

(2010) Larry J. Millet et al.   LAB ON A CHIP

A high-throughput microfluidic assay to study neurite response to growth factor gradients

(2010) Chandrasekhar R. Kothapalli et al.   LAB ON A CHIP

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511

(2010) Sergey Rodin et al.   NATURE BIOTECHNOLOGY

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Microfluidic Local Perfusion Chambers for the Visualization and Manipulation of Synapses

(2010) Anne M. Taylor et al.   NEURON

Burn Injury Reduces Neutrophil Directional Migration Speed in Microfluidic Devices

(2010) Kathryn L. Butler et al.   PLoS One

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Signaling by members of the TGF-β family in vascular morphogenesis and disease

(2010) Evangelia Pardali et al.   TRENDS IN CELL BIOLOGY

Artificial Stem Cell Niches

(2009) Matthias P. Lutolf et al.   ADVANCED MATERIALS

Microfluidic compartmentalized co-culture platform for CNS axon myelination research

(2009) Jaewon Park et al.   BIOMEDICAL MICRODEVICES

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

Recent developments in PDMS surface modification for microfluidic devices

(2009) Jinwen Zhou et al.   ELECTROPHORESIS

Transport-mediated angiogenesis in 3D epithelial coculture

(2009) Ryo Sudo et al.   FASEB JOURNAL

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

(2009) Frederico A.C. Azevedo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Laminin and fibronectin scaffolds enhance neural stem cell transplantation into the injured brain

(2009) Ciara C. Tate et al.   Journal of Tissue Engineering and Regenerative Medicine

Microfluidic platform for controlling the differentiation of embryoid bodies

(2009) Wai-To Fung et al.   LAB ON A CHIP

Microfluidic culture of single human embryonic stem cell colonies

(2009) Luis Gerardo Villa-Diaz et al.   LAB ON A CHIP

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

(2009) Carlos P. Huang et al.   LAB ON A CHIP

Microfluidic control of cell pairing and fusion

(2009) Alison M Skelley et al.   NATURE METHODS

Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia

(2009) Stefan A Grathwohl et al.   NATURE NEUROSCIENCE

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

The Parkinson chimera

(2009) A. J. Lees   NEUROLOGY

Differentiation of Neural Progenitor Cells in a Microfluidic Chip-Generated Cytokine Gradient

(2009) Joong Yull Park et al.   STEM CELLS

Cortical Factor Feedback Model for Cellular Locomotion and Cytofission

(2009) Shin I. Nishimura et al.   PLoS Computational Biology

Cell Culture Models in Microfluidic Systems

(2008) Ivar Meyvantsson et al.   Annual Review of Analytical Chemistry

Neurite growth in 3D collagen gels with gradients of mechanical properties

(2008) Harini G. Sundararaghavan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Mechanisms of neurodegeneration in Huntington’s disease

(2008) Joana M. Gil et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Regulation of Schwann cell function by the extracellular matrix

(2008) Michael A. Chernousov et al.   GLIA

A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

(2008) Shinsuke Nakagawa et al.   NEUROCHEMISTRY INTERNATIONAL

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE