Pathophysiology of the brain extracellular matrix: a new target for remyelination

Fibronectin aggregation in multiple sclerosis lesions impairs remyelination

(2013) Josephine M. J. Stoffels et al.   BRAIN

Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ

(2013) James C. Pendleton et al.   EXPERIMENTAL NEUROLOGY

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

(2012) Lorraine W. Lau et al.   ANNALS OF NEUROLOGY

Cortical remyelination: A new target for repair therapies in multiple sclerosis

(2012) Ansi Chang et al.   ANNALS OF NEUROLOGY

Digestion products of the PH20 hyaluronidase inhibit remyelination

(2012) Marnie Preston et al.   ANNALS OF NEUROLOGY

Scar-mediated inhibition and CSPG receptors in the CNS

(2012) Kartavya Sharma et al.   EXPERIMENTAL NEUROLOGY

Laminin regulates postnatal oligodendrocyte production by promoting oligodendrocyte progenitor survival in the subventricular zone

(2012) Jenne Relucio et al.   GLIA

The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury

(2012) Ryoji Tauchi et al.   Journal of Neuroinflammation

Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology

(2012) Tracey M Gloster et al.   Nature Chemical Biology

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans

(2012) Travis L Dickendesher et al.   NATURE NEUROSCIENCE

The perineuronal net component of the extracellular matrix in plasticity and epilepsy

(2012) Paulette A. McRae et al.   NEUROCHEMISTRY INTERNATIONAL

Chondroitinase and Growth Factors Enhance Activation and Oligodendrocyte Differentiation of Endogenous Neural Precursor Cells after Spinal Cord Injury

(2012) Soheila Karimi-Abdolrezaee et al.   PLoS One

A sulfated carbohydrate epitope inhibits axon regeneration after injury

(2012) J. M. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular matrix and perineuronal nets in CNS repair

(2011) Jessica C.F. Kwok et al.   Developmental Neurobiology

Chondroitinase treatment following spinal contusion injury increases migration of oligodendrocyte progenitor cells

(2011) Justin R. Siebert et al.   EXPERIMENTAL NEUROLOGY

Targeted downregulation of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase significantly mitigates chondroitin sulfate proteoglycan-mediated inhibition

(2011) Lohitash Karumbaiah et al.   GLIA

The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes

(2011) Justin R. Siebert et al.   JOURNAL OF NEUROCHEMISTRY

Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord

(2011) Karolina Kucharova et al.   Journal of Neuroinflammation

Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling

(2011) C. L. Tan et al.   JOURNAL OF NEUROSCIENCE

Leukocyte Common Antigen-Related Phosphatase Is a Functional Receptor for Chondroitin Sulfate Proteoglycan Axon Growth Inhibitors

(2011) D. Fisher et al.   JOURNAL OF NEUROSCIENCE

6-Sulphated Chondroitins Have a Positive Influence on Axonal Regeneration

(2011) Rachel Lin et al.   PLoS One

Expression and Effects of Hyaluronan and of the Hyaluronan-Binding Protein Hyaluronectin in Newborn Rat Brain Glial Cell Cultures

(2010) Stéphane Marret et al.   JOURNAL OF NEUROCHEMISTRY

Bral1: Its Role in Diffusion Barrier Formation and Conduction Velocity in the CNS

(2010) Y. Bekku et al.   JOURNAL OF NEUROSCIENCE

Reactive astrocytes as therapeutic targets for CNS disorders

(2010) Mary E. Hamby et al.   Neurotherapeutics

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Actomyosin contractility controls cell surface area of oligodendrocytes

(2009) Angelika Kippert et al.   BMC CELL BIOLOGY

A Disintegrin-like and Metalloprotease (Reprolysin-type) with Thrombospondin Type 1 Motif (ADAMTS) Superfamily: Functions and Mechanisms

(2009) Suneel S. Apte   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibronectin attenuates process outgrowth in oligodendrocytes by mislocalizing MMP-9 activity

(2009) Zuzana Šišková et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

PTP  Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

(2009) Y. Shen et al.   SCIENCE

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Elevated Matrix Metalloproteinase-9 and Degradation of Perineuronal Nets in Cerebrocortical Multiple Sclerosis Plaques

(2008) Elizabeth Gray et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation

(2008) Asya Rolls et al.   PLOS MEDICINE

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

(2007) Michael T. Fitch et al.   EXPERIMENTAL NEUROLOGY

A ‘GAG’ reflex prevents repair of the damaged CNS

(2007) Larry S. Sherman et al.   TRENDS IN NEUROSCIENCES