Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells

Moving towards treatments for spinal muscular atrophy: hopes and limits

(2015) Brunhilde Wirth et al.   EXPERT OPINION ON EMERGING DRUGS

AAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats

(2015) Kasey L Jackson et al.   Molecular Therapy-Methods & Clinical Development

Naturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo

(2014) Bence György et al.   BIOMATERIALS

Translational Fidelity of Intrathecal Delivery of Self-Complementary AAV9–Survival Motor Neuron 1 for Spinal Muscular Atrophy

(2014) Marco A. Passini et al.   HUMAN GENE THERAPY

Transendothelial migration of effector T cells across inflamed endothelial barriers does not require heparan sulfate proteoglycans

(2014) Liat Stoler-Barak et al.   INTERNATIONAL IMMUNOLOGY

Activation of Peroxisome Proliferator-Activated Receptor   (PPAR ) Suppresses Rho GTPases in Human Brain Microvascular Endothelial Cells and Inhibits Adhesion and Transendothelial Migration of HIV-1 Infected Monocytes

(2014) S. H. Ramirez et al.   JOURNAL OF IMMUNOLOGY

Recombinant Adeno-Associated Virus Utilizes Host Cell Nuclear Import Machinery To Enter the Nucleus

(2014) S. C. Nicolson et al.   JOURNAL OF VIROLOGY

Global CNS Transduction of Adult Mice by Intravenously Delivered rAAVrh.8 and rAAVrh.10 and Nonhuman Primates by rAAVrh.10

(2014) Bin Yang et al.   MOLECULAR THERAPY

Gene Therapy for the Nervous System: Challenges and New Strategies

(2014) Casey A. Maguire et al.   Neurotherapeutics

Chondroitin Sulfate is the Primary Receptor for a Peptide-Modified AAV That Targets Brain Vascular Endothelium In Vivo

(2014) James C Geoghegan et al.   Molecular Therapy-Nucleic Acids

Mouse Gender Influences Brain Transduction by Intravascularly Administered AAV9

(2013) Casey A Maguire et al.   MOLECULAR THERAPY

Cytoplasmic Trafficking, Endosomal Escape, and Perinuclear Accumulation of Adeno-Associated Virus Type 2 Particles Are Facilitated by Microtubule Network

(2012) P.-J. Xiao et al.   JOURNAL OF VIROLOGY

Identification of the Galactose Binding Domain of the Adeno-Associated Virus Serotype 9 Capsid

(2012) C. L. Bell et al.   JOURNAL OF VIROLOGY

Microvesicle-associated AAV Vector as a Novel Gene Delivery System

(2012) Casey A Maguire et al.   MOLECULAR THERAPY

Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors

(2011) K Varadi et al.   GENE THERAPY

Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates

(2011) Lluis Samaranch et al.   HUMAN GENE THERAPY

TerminalN-Linked Galactose Is the Primary Receptor for Adeno-associated Virus 9

(2011) Shen Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice

(2011) Christie L. Bell et al.   JOURNAL OF CLINICAL INVESTIGATION

Preclinical Differences of Intravascular AAV9 Delivery to Neurons and Glia: A Comparative Study of Adult Mice and Nonhuman Primates

(2011) Steven J Gray et al.   MOLECULAR THERAPY

Systemic Gene Delivery in Large Species for Targeting Spinal Cord, Brain, and Peripheral Tissues for Pediatric Disorders

(2011) Adam K Bevan et al.   MOLECULAR THERAPY

Quantitative 3D Tracing of Gene-delivery Viral Vectors in Human Cells and Animal Tissues

(2011) Ping-Jie Xiao et al.   MOLECULAR THERAPY

Gender Dimorphism in the Gut: Mucosal Protection by Estrogen Stimulation of IgA Transcytosis

(2011) Mark E. Diebel et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier

(2010) Michael J Bernas et al.   Nature Protocols

Intravenous Administration of Self-complementary AAV9 Enables Transgene Delivery to Adult Motor Neurons

(2009) Sandra Duque et al.   MOLECULAR THERAPY

Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy

(2009) Yong Hong Chen et al.   NATURE MEDICINE

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

(2008) Kevin D Foust et al.   NATURE BIOTECHNOLOGY