A 3D human neural cell culture system for modeling Alzheimer's disease

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

(2014) Christina R. Muratore et al.   HUMAN MOLECULAR GENETICS

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors

(2014) Andrew A. Sproul et al.   PLoS One

Bioengineered functional brain-like cortical tissue

(2014) M. D. Tang-Schomer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons

(2013) Dawei Zhang et al.   BIOMATERIALS

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

(2013) Takayuki Kondo et al.   Cell Stem Cell

Taurine Enhances the Growth of Neural Precursors Derived from Fetal Human Brain and Promotes Neuronal Specification

(2013) Reyna Hernández-Benítez et al.   DEVELOPMENTAL NEUROSCIENCE

Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells

(2013) Zohara L Chaudhry et al.   NEUROLOGICAL RESEARCH

Survival of transplanted human neural stem cell line (ReNcell VM) into the rat brain with and without immunosuppression

(2012) M. Hovakimyan et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

iPSCs to the Rescue in Alzheimer's Research

(2012) Se Hoon Choi et al.   Cell Stem Cell

TALE nucleases: tailored genome engineering made easy

(2012) Claudio Mussolino et al.   CURRENT OPINION IN BIOTECHNOLOGY

Alzheimer's disease in a dish: promises and challenges of human stem cell models

(2012) J. E. Young et al.   HUMAN MOLECULAR GENETICS

Glycogen synthase kinase-3beta regulates differentiation-induced apoptosis of human neural progenitor cells

(2012) Alexandra Jaeger et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Introducing Amylo-Glo, a novel fluorescent amyloid specific histochemical tracer especially suited for multiple labeling and large scale quantification studies

(2012) Larry Schmued et al.   JOURNAL OF NEUROSCIENCE METHODS

Capture of Neuroepithelial-Like Stem Cells from Pluripotent Stem Cells Provides a Versatile System for In Vitro Production of Human Neurons

(2012) Anna Falk et al.   PLoS One

3D Differentiation of Neural Stem Cells in Macroporous Photopolymerizable Hydrogel Scaffolds

(2012) Hang Li et al.   PLoS One

A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome

(2012) Y. Shi et al.   Science Translational Medicine

Modeling familial Alzheimer's disease with induced pluripotent stem cells

(2011) Takuya Yagi et al.   HUMAN MOLECULAR GENETICS

Self-formation of functional adenohypophysis in three-dimensional culture

(2011) Hidetaka Suga et al.   NATURE

Differentiation of human neural progenitor cells regulated by Wnt-3a

(2010) Rayk Hübner et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of 3D-scaffold formation on differentiation and survival in human neural progenitor cells

(2010) Stefanie Ortinau et al.   Biomedical Engineering Online

Small molecule GSK-3 inhibitors increase neurogenesis of human neural progenitor cells

(2010) Christian Lange et al.   NEUROSCIENCE LETTERS

Human Stem Cell-Derived Neurons: A System to Study Human Tau Function and Dysfunction

(2010) Mariangela Iovino et al.   PLoS One

Matrigel: A complex protein mixture required for optimal growth of cell culture

(2010) Chris S. Hughes et al.   PROTEOMICS

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

(2009) Krishanu Saha et al.   Cell Stem Cell

MicroRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets

(2009) M. T. N. Le et al.   MOLECULAR AND CELLULAR BIOLOGY

Protection of neurons derived from human neural progenitor cells by veratridine

(2009) Peter J. Morgan et al.   NEUROREPORT

Zinc-finger Nucleases: The Next Generation Emerges

(2008) Toni Cathomen et al.   MOLECULAR THERAPY

Animal models of Alzheimer's disease and frontotemporal dementia

(2008) Jürgen Götz et al.   NATURE REVIEWS NEUROSCIENCE