End-Plate Acetylcholine Receptor: Structure, Mechanism, Pharmacology, and Disease

Patch-clamp amplifiers on a chip

(2010) Pujitha Weerakoon et al.   JOURNAL OF NEUROSCIENCE METHODS

Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism

(2010) Y. Bourne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Channel Current Through Nicotinic Receptor Produced by Closure of Binding Site C-Loop

(2009) Hai-Long Wang et al.   BIOPHYSICAL JOURNAL

Biophysics and Structure of the Patch and the Gigaseal

(2009) Thomas M. Suchyna et al.   BIOPHYSICAL JOURNAL

Decremental Response to High-Frequency Trains of Acetylcholine Pulses but Unaltered Fractional Ca2+Currents in a Panel of “Slow-Channel Syndrome” Nicotinic Receptor Mutants

(2009) Sergio Elenes et al.   JOURNAL OF GENERAL PHYSIOLOGY

Binding to Gating Transduction in Nicotinic Receptors: Cys-Loop Energetically Couples to Pre-M1 and M2-M3 Regions

(2009) W. Y. Lee et al.   JOURNAL OF NEUROSCIENCE

Number and Locations of Agonist Binding Sites Required to Activate Homomeric Cys-Loop Receptors

(2009) D. Rayes et al.   JOURNAL OF NEUROSCIENCE

Agonist and blocking actions of choline and tetramethylammonium on human muscle acetylcholine receptors

(2009) Remigijus Lape et al.   JOURNAL OF PHYSIOLOGY-LONDON

Detection and trapping of intermediate states priming nicotinic receptor channel opening

(2009) Nuriya Mukhtasimova et al.   NATURE

Inhibition Mechanism of the Acetylcholine Receptor by α-Neurotoxins as Revealed by Normal-Mode Dynamics†

(2008) Abraham O. Samson et al.   BIOCHEMISTRY

Design and expression of human α7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties

(2008) Marios Zouridakis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance

(2008) Scott B. Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Congenital myasthenia–related AChR δ subunit mutation interferes with intersubunit communication essential for channel gating

(2008) Xin-Ming Shen et al.   JOURNAL OF CLINICAL INVESTIGATION

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer

(2008) Gisela D Cymes et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Control of Cation Permeation through the Nicotinic Receptor Channel

(2008) Hai-Long Wang et al.   PLoS Computational Biology

Atomic interactions of neonicotinoid agonists with AChBP: Molecular recognition of the distinctive electronegative pharmacophore

(2008) T. T. Talley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA