P2×7 purinergic signaling in dilated cardiomyopathy induced by auto-immunity against muscarinic M2 receptors: autoantibody levels, heart functionality and cytokine expression

Altered expression of P2Y2 and P2X7 purinergic receptors in the isolated rat heart mediates ischemia–reperfusion injury

(2015) Miriam Granado et al.   VASCULAR PHARMACOLOGY

A Human Type 5 Adenovirus-Based Trypanosoma cruzi Therapeutic Vaccine Re-programs Immune Response and Reverses Chronic Cardiomyopathy

(2015) Isabela Resende Pereira et al.   PLoS Pathogens

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

A P2X7 receptor antagonist attenuates experimental autoimmune myocarditis via suppressed myocardial CD4+ T and macrophage infiltration and NADPH oxidase 2/4 expression in mice

(2014) Hirofumi Zempo et al.   HEART AND VESSELS

The Transcription Factors T-bet and Runx Are Required for the Ontogeny of Pathogenic Interferon-γ-Producing T Helper 17 Cells

(2014) Yan Wang et al.   IMMUNITY

Lineage stability and phenotypic plasticity of Foxp3+regulatory T cells

(2014) Shohei Hori   IMMUNOLOGICAL REVIEWS

Cardiac fibroblasts mediate IL-17A–driven inflammatory dilated cardiomyopathy

(2014) Lei Wu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myocardial Mechanics in Cardiomyopathies

(2014) Karen Modesto et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Interleukin-23 Deficiency Leads to Impaired Wound Healing and Adverse Prognosis After Myocardial Infarction

(2013) Konstantinos Savvatis et al.   Circulation-Heart Failure

Fatal Eosinophilic Myocarditis Develops in the Absence of IFN-  and IL-17A

(2013) J. G. Barin et al.   JOURNAL OF IMMUNOLOGY

IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8+ T cell responses to influenza A virus

(2013) Iris K Pang et al.   NATURE IMMUNOLOGY

Interferon-γ Causes Cardiac Myocyte Atrophy via Selective Degradation of Myosin Heavy Chain in a Model of Chronic Myocarditis

(2012) Pippa F. Cosper et al.   AMERICAN JOURNAL OF PATHOLOGY

Susceptibility to autoimmune myocarditis is associated with intrinsic differences in CD4+T cells

(2012) P. Chen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Challenge of Chronically Infected Mice with Homologous Trypanosoma cruzi Parasites Enhances the Immune Response but Does Not Modify Cardiopathy: Implications for the Design of a Therapeutic Vaccine

(2012) Christian Emerson Rosas-Jorquera et al.   Clinical and Vaccine Immunology

P2 receptors and immunity

(2012) Amel Rayah et al.   MICROBES AND INFECTION

Deficient Regulatory T Cell Activity and Low Frequency of IL-17-Producing T Cells Correlate with the Extent of Cardiomyopathy in Human Chagas' Disease

(2012) Paulo Marcos Matta Guedes et al.   PLoS Neglected Tropical Diseases

IL-17RA Signaling Reduces Inflammation and Mortality during Trypanosoma cruzi Infection by Recruiting Suppressive IL-10-Producing Neutrophils

(2012) Jimena Tosello Boari et al.   PLoS Pathogens

Chronic Inflammatory Cardiomyopathy of Interferon γ–Overexpressing Transgenic Mice Is Mediated by Tumor Necrosis Factor-α

(2011) Michael Torzewski et al.   AMERICAN JOURNAL OF PATHOLOGY

P2X7 receptor agonists pre- and postcondition the heart against ischemia-reperfusion injury by opening pannexin-1/P2X7 channels

(2011) Donald A. Vessey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

ST-segment depression and T-wave inversion: Classification, differential diagnosis, and caveats

(2011) E. B. HANNA et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

(2011) E. Mezzaroma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors

(2011) U. Schenk et al.   Science Signaling

The Role of the P2X7 Receptor in Infectious Diseases

(2011) Catherine M. Miller et al.   PLoS Pathogens

Th1 and Th17 cells

(2010) Jesse M. Damsker et al.   Annals of the New York Academy of Sciences

Interleukin-17A Is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy

(2010) G. Christian Baldeviano et al.   CIRCULATION RESEARCH

Increased P2X7R expression in atrial cardiomyocytes of caveolin-1 deficient mice

(2010) K. Barth et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The Mechanism of the Negative Chronotropic and Dromotropic Actions of Adenosine 5ʼ-triphosphate in the Heart: An Update

(2010) Amir Pelleg et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

(2010) Helena S. Domingues et al.   PLoS One

IL-17 Produced during Trypanosoma cruzi Infection Plays a Central Role in Regulating Parasite-Induced Myocarditis

(2010) Paulo Marcos da Matta Guedes et al.   PLoS Neglected Tropical Diseases

Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling

(2009) Yeonseok Chung et al.   IMMUNITY

Late Developmental Plasticity in the T Helper 17 Lineage

(2009) Yun Kyung Lee et al.   IMMUNITY

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regions

(2009) Hanny Musa et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Are CD4+CD25-Foxp3+ cells in untreated new-onset lupus patients regulatory T cells?

(2009) Hua-xia Yang et al.   ARTHRITIS RESEARCH & THERAPY

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

(2008) Dror Luger et al.   JOURNAL OF EXPERIMENTAL MEDICINE