Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model

Tau Oligomers Derived from Traumatic Brain Injury Cause Cognitive Impairment and Accelerate Onset of Pathology in Htau Mice

(2016) Julia Gerson et al.   JOURNAL OF NEUROTRAUMA

Glucose Metabolic Brain Networks in Early-Onset vs. Late-Onset Alzheimer's Disease

(2016) Jinyong Chung et al.   Frontiers in Aging Neuroscience

p38 MAPK Inhibition Improves Synaptic Plasticity and Memory in Angiotensin II-dependent Hypertensive Mice

(2016) Hai-long Dai et al.   Scientific Reports

Glucose deprivation increases tau phosphorylation via P38 mitogen-activated protein kinase

(2015) Elisabetta Lauretti et al.   AGING CELL

Pharmacologic Inhibition of 5-Lipoxygenase Improves Memory, Rescues Synaptic Dysfunction, and Ameliorates Tau Pathology in a Transgenic Model of Tauopathy

(2015) Phillip F. Giannopoulos et al.   BIOLOGICAL PSYCHIATRY

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease

(2015) Naoyuki Sato et al.   Frontiers in Aging Neuroscience

Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer’s disease

(2015) Fernanda G. De Felice et al.   Frontiers in Aging Neuroscience

Glucose regulation, cognition, and brain MRI in type 2 diabetes: a systematic review

(2015) Stefan L C Geijselaers et al.   Lancet Diabetes & Endocrinology

Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice

(2014) Antonio Di Meco et al.   NEUROBIOLOGY OF AGING

Glycemic Variability and Acute Ischemic Stroke: The Missing Link?

(2014) Emmanuel I. González-Moreno et al.   Translational Stroke Research

Glucose deprivation induces reticulum stress by the PERK pathway and caspase-7- and calpain-mediated caspase-12 activation

(2013) Selene García de la Cadena et al.   APOPTOSIS

Activation of the endoplasmic reticulum stress response by the amyloid-beta 1–40 peptide in brain endothelial cells

(2013) Ana Catarina R.G. Fonseca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

5-Lipoxygenase Activating Protein Reduction Ameliorates Cognitive Deficit, Synaptic Dysfunction, and Neuropathology in a Mouse Model of Alzheimer’s Disease

(2013) Phillip F. Giannopoulos et al.   BIOLOGICAL PSYCHIATRY

Sugar for the brain: the role of glucose in physiological and pathological brain function

(2013) Philipp Mergenthaler et al.   TRENDS IN NEUROSCIENCES

Dementia and cognitive decline in type 2 diabetes and prediabetic stages: towards targeted interventions

(2013) Geert Jan Biessels et al.   Lancet Diabetes & Endocrinology

Soluble forms of tau are toxic in Alzheimer’s disease

(2012) Katherine Kopeikina et al.   Translational Neuroscience

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology

(2009) M. Polydoro et al.   JOURNAL OF NEUROSCIENCE

Targeting p38 MAPK pathway for the treatment of Alzheimer's disease

(2009) Lenka Munoz et al.   NEUROPHARMACOLOGY

AMP-activated Protein Kinase and p38 MAPK ActivateO-GlcNAcylation of Neuronal Proteins during Glucose Deprivation

(2008) Win D. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis

(2008) Tracy O'Connor et al.   NEURON