- Home
- Publications
- Publication Search
- Publication Details
Title
Sam68 is a druggable vulnerability point in cancer stem cells
Authors
Keywords
-
Journal
CANCER AND METASTASIS REVIEWS
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-04
DOI
10.1007/s10555-023-10145-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Comparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness
- (2022) Chia-Hung Lin et al. Cancers
- Lipophagy-ICAM-1 pathway associated with fatty acid and oxygen deficiencies is involved in poor prognoses of ovarian clear cell carcinoma
- (2022) Shiro Koizume et al. BRITISH JOURNAL OF CANCER
- ebv-circRPMS1 promotes the progression of EBV-associated gastric carcinoma via Sam68-dependent activation of METTL3
- (2022) Jing-yue Zhang et al. CANCER LETTERS
- Effective targeting of breast cancer stem cells by combined inhibition of Sam68 and Rad51
- (2022) Alice Turdo et al. ONCOGENE
- Smad4 and p53 synergize in suppressing autochthonous intestinal cancer
- (2022) Jun Won Park et al. Cancer Medicine
- RNA-Binding Proteins in the Regulation of Adipogenesis and Adipose Function
- (2022) Pengpeng Zhang et al. Cells
- Cdk1-mediated threonine phosphorylation of Sam68 modulates its RNA binding, alternative splicing activity and cellular functions
- (2022) Idir Malki et al. NUCLEIC ACIDS RESEARCH
- G9a controls pluripotent-like identity and tumor-initiating function in human colorectal cancer
- (2021) Christopher J. Bergin et al. ONCOGENE
- Cancer Stemness: p53 at the Wheel
- (2021) Dishari Ghatak et al. Frontiers in Oncology
- Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling
- (2021) Elliott D. Bayle et al. JOURNAL OF MEDICINAL CHEMISTRY
- Slow-cycling (dormant) cancer cells in therapy resistance, cancer relapse and metastasis
- (2021) Sukanya Basu et al. SEMINARS IN CANCER BIOLOGY
- Sam68 promotes hepatic gluconeogenesis via CRTC2
- (2021) Aijun Qiao et al. Nature Communications
- Sam68 contributes to intestinal inflammation in experimental and human colitis
- (2021) Wendy A. Goodman et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cancer‐associated mutations in VAV1 trigger variegated signaling outputs and T‐cell lymphomagenesis
- (2021) Javier Robles‐Valero et al. EMBO JOURNAL
- Emerging role of G9a in cancer stemness and promises as a therapeutic target
- (2021) Joshua R. Haebe et al. Oncogenesis
- Pharmacological targeting of Sam68 functions in colorectal cancer stem cells
- (2021) Angelique N. Masibag et al. iScience
- Gain-of-function genetic alterations of G9a drive oncogenesis
- (2020) Shinichiro Kato et al. Cancer Discovery
- Sam68 promotes aerobic glycolysis in colorectal cancer by regulating PKM2 alternative splicing
- (2020) Jing Zhao et al. Annals of Translational Medicine
- A Pygopus 2-histone interaction is critical for cancer cell de-differentiation and progression in malignant breast cancer
- (2020) Meera Saxena et al. CANCER RESEARCH
- Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome
- (2020) Je-Hwan Lee et al. Blood Advances
- The Crosstalk between FAK and Wnt Signaling Pathways in Cancer and Its Therapeutic Implication
- (2020) Janine Wörthmüller et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Functional Interaction between U1snRNP and Sam68 Insures Proper 3′ End Pre-mRNA Processing during Germ Cell Differentiation
- (2019) Chiara Naro et al. Cell Reports
- The promoter associated non-coding RNA pncCCND1_B assembles a protein-RNA complex to regulate cyclin D1 transcription in Ewing sarcoma
- (2019) Ramona Palombo et al. CANCER RESEARCH
- Sam68 is required for the growth and survival of nonmelanoma skin cancer
- (2019) Kai Fu et al. Cancer Medicine
- Sam68 impedes the recovery of arterial injury by augmenting inflammatory response
- (2019) Shuling Han et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- HBO1 is required for the maintenance of leukaemia stem cells
- (2019) Laura MacPherson et al. NATURE
- Clinical significance and effect of Sam68 expression in gastric cancer
- (2018) Jinzhang Xiao et al. Oncology Letters
- Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence
- (2018) Allison L. Boyd et al. CANCER CELL
- Vav1 mutations identified in human cancers give rise to different oncogenic phenotypes
- (2018) Batel Shalom et al. Oncogenesis
- Epigenetics in cancer stem cells
- (2017) Tan Boon Toh et al. Molecular Cancer
- A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
- (2017) Felipe de Sousa e Melo et al. NATURE
- Visualization and targeting of LGR5+ human colon cancer stem cells
- (2017) Mariko Shimokawa et al. NATURE
- Wnt/ -catenin-dependent acetylation of Pygo2 by CBP/p300 histone acetyltransferase family members
- (2016) P. G. P. Andrews et al. BIOCHEMICAL JOURNAL
- FOXD1–ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells
- (2016) Peng Cheng et al. CANCER RESEARCH
- Sam68 functions as a transcriptional coactivator of the p53 tumor suppressor
- (2016) Naomi Li et al. NUCLEIC ACIDS RESEARCH
- CWP232228 targets liver cancer stem cells through Wnt/β‑catenin signaling: a novel therapeutic approach for liver cancer treatment
- (2016) Ji‑Young Kim et al. Oncotarget
- Anti-cancer Effect of Luminacin, a Marine Microbial Extract, in Head and Neck Squamous Cell Carcinoma Progression via Autophagic Cell Death
- (2016) Yoo Seob Shin et al. Cancer Research and Treatment
- Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation
- (2016) Xin Sun et al. PLOS BIOLOGY
- Sam68/KHDRBS1-dependent NF-κB activation confers radioprotection to the colon epithelium in γ-irradiated mice
- (2016) Kai Fu et al. eLife
- Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing
- (2016) Piergiorgio La Rosa et al. eLife
- Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation
- (2016) Kai Fu et al. eLife
- Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas
- (2016) Maria V. Bogachek et al. Stem Cell Reports
- The NF-κB Pathway and Cancer Stem Cells
- (2016) Amanda Rinkenbaugh et al. Cells
- Wnt/ -Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
- (2015) G.-B. Jang et al. CANCER RESEARCH
- CONSORT
- (2015) Lan Wang et al. MEDICINE
- Sam68 Regulates S6K1 Alternative Splicing during Adipogenesis
- (2015) Jingwen Song et al. MOLECULAR AND CELLULAR BIOLOGY
- SAM68: Signal Transduction and RNA Metabolism in Human Cancer
- (2015) Paola Frisone et al. Biomed Research International
- Evolution of the Cancer Stem Cell Model
- (2014) Antonija Kreso et al. Cell Stem Cell
- High Sam68 expression predicts poor prognosis in non-small cell lung cancer
- (2014) Z. Zhang et al. Clinical & Translational Oncology
- Molecular Pathways: Epigenetic Modulation of Wnt-Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells
- (2014) Y. D. Benoit et al. CLINICAL CANCER RESEARCH
- The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis
- (2014) P. Bielli et al. EMBO REPORTS
- Can we safely target the WNT pathway?
- (2014) Michael Kahn NATURE REVIEWS DRUG DISCOVERY
- Wnt/Catenin Signaling in Adult Stem Cell Physiology and Disease
- (2014) Alexander Ring et al. Stem Cell Reviews and Reports
- Role of Sam68 in Post-Transcriptional Gene Regulation
- (2013) Flora Sánchez-Jiménez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Self-renewal as a therapeutic target in human colorectal cancer
- (2013) Antonija Kreso et al. NATURE MEDICINE
- Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3
- (2013) P. Mao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA-binding protein Sam68 controls synapse number and local -actin mRNA metabolism in dendrites
- (2013) M. E. Klein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The nuclear protein Sam68 is redistributed to the cytoplasm and is involved in PI3K/Akt activation during EV71 infection
- (2013) Hua Zhang et al. VIRUS RESEARCH
- Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells
- (2013) Kai Fu et al. Nature Communications
- Cancer Stem Cells: Current Status and Evolving Complexities
- (2012) Jane E. Visvader et al. Cell Stem Cell
- Migracins A and B, new inhibitors of cancer cell migration, produced by Streptomyces sp.
- (2012) Yuhei Arai et al. JOURNAL OF ANTIBIOTICS
- The Sam68 STAR RNA-Binding Protein Regulates mTOR Alternative Splicing during Adipogenesis
- (2012) Marc-Étienne Huot et al. MOLECULAR CELL
- Emerging roles for Sam68 in adipogenesis and neuronal development
- (2012) Gillian Vogel et al. RNA Biology
- Sam68 expression and cytoplasmic localization is correlated with lymph node metastasis as well as prognosis in patients with early-stage cervical cancer
- (2011) Z. Li et al. ANNALS OF ONCOLOGY
- SAM68 Regulates Neuronal Activity-Dependent Alternative Splicing of Neurexin-1
- (2011) Takatoshi Iijima et al. CELL
- The RNA-binding protein Sam68 is a multifunctional player in human cancer
- (2011) P. Bielli et al. ENDOCRINE-RELATED CANCER
- Met Receptors Induce Sam68-dependent Cell Migration by Activation of Alternate Extracellular Signal-regulated Kinase Family Members
- (2011) Alessia Locatelli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sam68 Guest STARs in TNF-α Signaling
- (2011) Gregory T. Kunkel et al. MOLECULAR CELL
- Sam68 Is Required for Both NF-κB Activation and Apoptosis Signaling by the TNF Receptor
- (2011) Parameswaran Ramakrishnan et al. MOLECULAR CELL
- Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells
- (2011) Maria Paola Paronetto et al. NUCLEIC ACIDS RESEARCH
- Mechanisms of HGF/Met Signaling to Brk and Sam68 in Breast Cancer Progression
- (2011) Alessia Locatelli et al. Hormones & Cancer
- Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients
- (2010) Chantal Sellier et al. EMBO JOURNAL
- The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy
- (2010) Simona Pedrotti et al. EMBO JOURNAL
- Sam68 regulates EMT through alternative splicing–activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene
- (2010) Cristina Valacca et al. JOURNAL OF CELL BIOLOGY
- Sam68 up-regulation correlates with, and its down-regulation inhibits, proliferation and tumourigenicity of breast cancer cells
- (2010) Libing Song et al. JOURNAL OF PATHOLOGY
- Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies
- (2009) Prabhakar Rajan et al. BMC CELL BIOLOGY
- Expression and Cytoplasmic Localization of SAM68 Is a Significant and Independent Prognostic Marker for Renal Cell Carcinoma
- (2009) Z. Zhang et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Alternative Splicing of the Cyclin D1 Proto-Oncogene Is Regulated by the RNA-Binding Protein Sam68
- (2009) M. P. Paronetto et al. CANCER RESEARCH
- Regulation of Vascular Contractility and Blood Pressure by the E2F2 Transcription Factor
- (2009) Junlan Zhou et al. CIRCULATION
- Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis
- (2009) Maria Paola Paronetto et al. JOURNAL OF CELL BIOLOGY
- An Adaptor Role for Cytoplasmic Sam68 in Modulating Src Activity during Cell Polarization
- (2009) M.-E. Huot et al. MOLECULAR AND CELLULAR BIOLOGY
- Drug–target identification from total cellular lysate by drug-induced conformational changes
- (2008) Yoichi Nishiya et al. ANALYTICAL BIOCHEMISTRY
- Stem cell concepts renew cancer research
- (2008) J. E. Dick BLOOD
- Sam68 Regulates a Set of Alternatively Spliced Exons during Neurogenesis
- (2008) G. Chawla et al. MOLECULAR AND CELLULAR BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started