Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation

Metalloprotease NleC Suppresses Host NF-κB/Inflammatory Responses by Cleaving p65 and Interfering with the p65/RPS3 Interaction

(2015) Andrea Hodgson et al.   PLoS Pathogens

The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy

(2014) M Li et al.   ONCOGENE

Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells

(2013) Kai Fu et al.   Nature Communications

ATM Phosphorylation of Mdm2 Ser394 Regulates the Amplitude and Duration of the DNA Damage Response in Mice

(2012) Hugh S. Gannon et al.   CANCER CELL

On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1

(2012) X. Luo et al.   GENES & DEVELOPMENT

HMGN1 Protein Regulates Poly(ADP-ribose) Polymerase-1 (PARP-1) Self-PARylation in Mouse Fibroblasts

(2012) Aya Masaoka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of an N-terminal Truncation of the NF-κB p65 Subunit That Specifically Modulates Ribosomal Protein S3-dependent NF-κB Gene Expression

(2012) Eric M. Wier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair

(2012) Sophie E. Polo et al.   MOLECULAR CELL

Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response

(2012) Petra Beli et al.   MOLECULAR CELL

The Sam68 STAR RNA-Binding Protein Regulates mTOR Alternative Splicing during Adipogenesis

(2012) Marc-Étienne Huot et al.   MOLECULAR CELL

Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors

(2012) Elisabet Wahlberg et al.   NATURE BIOTECHNOLOGY

A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

(2012) Britt Adamson et al.   NATURE CELL BIOLOGY

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

(2012) Bryan A. Gibson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CHFR is important for the first wave of ubiquitination at DNA damage sites

(2012) Chao Liu et al.   NUCLEIC ACIDS RESEARCH

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks

(2012) Jana Krietsch et al.   NUCLEIC ACIDS RESEARCH

Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1

(2012) M.-F. Langelier et al.   SCIENCE

SAM68 Regulates Neuronal Activity-Dependent Alternative Splicing of Neurexin-1

(2011) Takatoshi Iijima et al.   CELL

The RNA-binding protein Sam68 is a multifunctional player in human cancer

(2011) P. Bielli et al.   ENDOCRINE-RELATED CANCER

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7

(2011) Fengyi Wan et al.   NATURE IMMUNOLOGY

Chfr and RNF8 synergistically regulate ATM activation

(2011) Jiaxue Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

(2011) Z. Mao et al.   SCIENCE

Poly(ADP-Ribose) Polymerase Inhibition: "Targeted" Therapy for Triple-Negative Breast Cancer

(2010) C. K. Anders et al.   CLINICAL CANCER RESEARCH

PARP-3 Is a Mono-ADP-ribosylase That Activates PARP-1 in the Absence of DNA

(2010) Olga Loseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets

(2010) Raga Krishnakumar et al.   MOLECULAR CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

(2010) Michael O. Hottiger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

(2009) Gianluca Papeo et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis

(2009) Maria Paola Paronetto et al.   JOURNAL OF CELL BIOLOGY

Suppression of HIV-1 Nef Translation by Sam68 Mutant-Induced Stress Granules and nef mRNA Sequestration

(2009) Jorge Henao-Mejia et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

BRCA1 and its toolbox for the maintenance of genome integrity

(2009) Michael S.Y. Huen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells

(2009) Xiangduo Kong et al.   NUCLEIC ACIDS RESEARCH

Regulation of gene expression by the RNA-binding protein Sam68 in cancer

(2008) Prabhakar Rajan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation

(2008) W Lee Kraus   CURRENT OPINION IN CELL BIOLOGY

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS

Spatiotemporal dynamics of regulatory protein recruitment at DNA damage sites

(2008) Oliver Mortusewicz et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor

(2008) P Rajan et al.   JOURNAL OF PATHOLOGY

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

(2008) Jean-Philippe Gagné et al.   NUCLEIC ACIDS RESEARCH

Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes

(2008) R. Krishnakumar et al.   SCIENCE