Pharmacological targeting of Sam68 functions in colorectal cancer stem cells

G9a controls pluripotent-like identity and tumor-initiating function in human colorectal cancer

(2021) Christopher J. Bergin et al.   ONCOGENE

Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome

(2020) Je-Hwan Lee et al.   Blood Advances

The Crosstalk between FAK and Wnt Signaling Pathways in Cancer and Its Therapeutic Implication

(2020) Janine Wörthmüller et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

(2019) Evelyne Lima-Fernandes et al.   Nature Communications

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

(2019) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Selective Wnt/β-catenin Small-molecule Inhibitor CWP232228 Impairs Tumor Growth of Colon Cancer

(2019) JIN YOUNG KIM et al.   ANTICANCER RESEARCH

Cancer modeling meets human organoid technology

(2019) David Tuveson et al.   SCIENCE

QMEANDisCo – Distance Constraints Applied on Model Quality Estimation

(2019) Gabriel Studer et al.   BIOINFORMATICS

Knockdown of laminin α5 stimulates intestinal cell differentiation

(2018) Manon Lepage et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

OUP accepted manuscript

(2018)   BIOINFORMATICS

Peptidomimetic blockade of MYB in acute myeloid leukemia

(2018) Kavitha Ramaswamy et al.   Nature Communications

Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence

(2018) Allison L. Boyd et al.   CANCER CELL

Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences

(2018) Anqi Zhu et al.   BIOINFORMATICS

FINDSITEcomb2.0: A New Approach for Virtual Ligand Screening of Proteins and Virtual Target Screening of Biomolecules

(2018) Hongyi Zhou et al.   Journal of Chemical Information and Modeling

Multifaceted Interpretation of Colon Cancer Stem Cells

(2017) Yuichiro Hatano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

(2017) Miguel Crespo et al.   NATURE MEDICINE

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Selective inhibitor of Wnt/β-catenin/CBP signaling ameliorates hepatitis C virus-induced liver fibrosis in mouse model

(2017) Yuko Tokunaga et al.   Scientific Reports

CWP232228 targets liver cancer stem cells through Wnt/β‑catenin signaling: a novel therapeutic approach for liver cancer treatment

(2016) Ji‑Young Kim et al.   Oncotarget

Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation

(2016) Kai Fu et al.   eLife

Wnt/ -Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells

(2015) G.-B. Jang et al.   CANCER RESEARCH

Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin

(2015) King Chi Chan et al.   Scientific Reports

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Molecular Pathways: Epigenetic Modulation of Wnt-Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells

(2014) Y. D. Benoit et al.   CLINICAL CANCER RESEARCH

The CREB-Binding Protein Inhibitor ICG-001 Suppresses Pancreatic Cancer Growth

(2014) M. D. Arensman et al.   MOLECULAR CANCER THERAPEUTICS

Self-renewal as a therapeutic target in human colorectal cancer

(2013) Antonija Kreso et al.   NATURE MEDICINE

Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

(2012) Eleftherios Sachlos et al.   CELL

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

(2011) M. Jinushi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Template-based protein structure modeling using TASSERVMT

(2011) Hongyi Zhou et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Cooperation between HNF-1α, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line

(2010) Yannick D. Benoit et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

(2010) Erin M. Bowers et al.   CHEMISTRY & BIOLOGY

Expression and Cytoplasmic Localization of SAM68 Is a Significant and Independent Prognostic Marker for Renal Cell Carcinoma

(2009) Z. Zhang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

An Adaptor Role for Cytoplasmic Sam68 in Modulating Src Activity during Cell Polarization

(2009) M.-E. Huot et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterization of human embryonic stem cells with features of neoplastic progression

(2009) Tamra E Werbowetski-Ogilvie et al.   NATURE BIOTECHNOLOGY

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS