RNA-Binding Proteins in the Regulation of Adipogenesis and Adipose Function

RNA‐binding protein YBX1 promotes brown adipogenesis and thermogenesis via PINK1/PRKN‐mediated mitophagy

(2022) Ruifan Wu et al.   FASEB JOURNAL

G-Quadruplex Regulation of VEGFA mRNA Translation by RBM4

(2022) Kangkang Niu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA-binding proteins: Underestimated contributors in tumorigenesis

(2022) Y. Zhao et al.   SEMINARS IN CANCER BIOLOGY

Advances in the study of RNA-binding proteins in diabetic complications

(2022) Xinyue Chen et al.   Molecular Metabolism

The Role of KH-Type Splicing Regulatory Protein (KSRP) for Immune Functions and Tumorigenesis

(2022) Kim-Alicia Palzer et al.   Cells

RNA-Binding Proteins Hold Key Roles in Function, Dysfunction, and Disease

(2021) Sophia Kelaini et al.   Biology-Basel

Shortening of HO1 3′UTRs by Alternative Polyadenylation Suppresses Adipogenesis in 3T3-L1

(2021) Jianwei Cui et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

RNA-Binding Proteins in the Post-transcriptional Control of Skeletal Muscle Development, Regeneration and Disease

(2021) De-Li Shi et al.   Frontiers in Cell and Developmental Biology

Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1

(2021) Gavin J Knott et al.   NUCLEIC ACIDS RESEARCH

Novel insights into adipose tissue heterogeneity

(2021) Tongtong Wang et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

YB-3 substitutes YB-1 in global mRNA binding

(2020) D. N. Lyabin et al.   RNA Biology

The RNA-binding protein HuR is a negative regulator in adipogenesis

(2020) Diana Teh Chee Siang et al.   Nature Communications

Understanding and targeting the disease‐related RNA binding protein human antigen R (HuR)

(2020) Christopher W. Schultz et al.   Wiley Interdisciplinary Reviews-RNA

RNA-Binding Proteins as Important Regulators of Long Non-Coding RNAs in Cancer

(2020) Katharina Jonas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms

(2020) Meredith Corley et al.   MOLECULAR CELL

Y-Box Binding Proteins in mRNP Assembly, Translation, and Stability Control

(2020) Daria Mordovkina et al.   Biomolecules

The Role of Pref-1 during Adipogenic Differentiation: An Overview of Suggested Mechanisms

(2020) Carina da Silva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NADP modulates RNA m6A methylation and adipogenesis via enhancing FTO activity

(2020) Lina Wang et al.   Nature Chemical Biology

The Diverse Functions of IMP2/IGF2BP2 in Metabolism

(2020) Ning Dai   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Novel Insights into Adipogenesis from the Perspective of Transcriptional and RNA N6‐Methyladenosine‐Mediated Post‐Transcriptional Regulation

(2020) Tongxing Song et al.   Advanced Science

Post-Transcriptional Regulation in Skeletal Muscle Development, Repair, and Disease

(2020) Kaitlin Weskamp et al.   TRENDS IN MOLECULAR MEDICINE

White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

(2020) Atefeh Rabiee et al.   Molecular Metabolism

Adipogenesis and metabolic health

(2019) Alexandra L. Ghaben et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM

(2019) Nina Ripin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism

(2019) Laura Regué et al.   MOLECULAR AND CELLULAR BIOLOGY

Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications

(2019) Michele Longo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions

(2019) Julia K. Nussbacher et al.   NEURON

N6-methyladenosine modifications: interactions with novel RNA-binding proteins and roles in signal transduction

(2019) Jiaxin Chen et al.   RNA Biology

Adipose HuR protects against diet-induced obesity and insulin resistance

(2019) Jingyuan Li et al.   Nature Communications

Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation

(2019) Laura Regué et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The endocrine function of adipose tissues in health and cardiometabolic disease

(2019) Ludger Scheja et al.   Nature Reviews Endocrinology

Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk

(2019) William W. Greenwald et al.   Nature Communications

The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance

(2019) Amy Cooke et al.   Cell Reports

The extensive role of miR-155 in malignant and non-malignant diseases

(2019) Diana Gulei et al.   MOLECULAR ASPECTS OF MEDICINE

Genetic and epigenetic control of adipose development

(2018) Olga Gulyaeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins

(2018) Jie Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Base modifications affecting RNA polymerase and reverse transcriptase fidelity

(2018) Vladimir Potapov et al.   NUCLEIC ACIDS RESEARCH

Regulation of microRNA function in animals

(2018) Luca F. R. Gebert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptional Control of Brown and Beige Fat Development and Function

(2018) Suzanne N. Shapira et al.   Obesity

Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis

(2017) Liping Li et al.   HUMAN MOLECULAR GENETICS

RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs

(2017) Jiexin Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

RNA modifications and structures cooperate to guide RNA–protein interactions

(2017) Cole J.T. Lewis et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance

(2017) A Visvanathan et al.   ONCOGENE

Transcriptome profiling in preadipocytes identifies long noncoding RNAs as Sam68 targets

(2017) Naomi Li et al.   Oncotarget

Emerging roles of RNA-binding proteins in diabetes and their therapeutic potential in diabetic complications

(2017) Curtis A. Nutter et al.   Wiley Interdisciplinary Reviews-RNA

Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation

(2017) Yuwei Jiang et al.   eLife

Type 2 Diabetes Susceptibility in the Greek-Cypriot Population: Replication of Associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 Polymorphisms

(2017) Christina Votsi et al.   Genes

Distinct functions of PPARγ isoforms in regulating adipocyte plasticity

(2016) Dylan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adipose tissue in control of metabolism

(2016) Liping Luo et al.   JOURNAL OF ENDOCRINOLOGY

Alternative polyadenylation and RNA-binding proteins

(2016) Ayse Elif Erson-Bensan   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Sam68 affects cell proliferation and apoptosis of human adult T-acute lymphoblastic leukemia cells via AKT/mTOR signal pathway

(2016) Qi Wang et al.   LEUKEMIA RESEARCH

Position-dependent interactions of Y-box protein 2 (YBX2) with mRNA enable mRNA storage in round spermatids by repressing mRNA translation and blocking translation-dependent mRNA decay

(2016) Kenneth C. Kleene   MOLECULAR REPRODUCTION AND DEVELOPMENT

Transcriptional and epigenetic control of brown and beige adipose cell fate and function

(2016) Takeshi Inagaki et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IGF2BP2 rs11705701 polymorphisms are associated with prediabetes in a Chinese population: A population-based case-control study

(2016) Liyuan Han et al.   Experimental and Therapeutic Medicine

Brown Fat and Browning for the Treatment of Obesity and Related Metabolic Disorders

(2016) So Hun Kim et al.   Diabetes & Metabolism Journal

Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population

(2016) Nagaraja M. Phani et al.   PLoS One

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

(2015) Ning Dai et al.   Cell Metabolism

Sam68 Regulates S6K1 Alternative Splicing during Adipogenesis

(2015) Jingwen Song et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6

(2015) Yu-Jie Hu et al.   NUCLEIC ACIDS RESEARCH

RBM4-MEF2C network constitutes a feed-forward circuit that facilitates the differentiation of brown adipocytes

(2015) Jung-Chun Lin   RNA Biology

Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression

(2015) Elizabeth Snyder et al.   PLoS Genetics

Emerging role for RNA binding motif protein 4 in the development of brown adipocytes

(2014) Jung-Chun Lin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Splicing Factor RBM4 Controls Apoptosis, Proliferation, and Migration to Suppress Tumor Progression

(2014) Yang Wang et al.   CANCER CELL

Prdm16 Is Required for the Maintenance of Brown Adipocyte Identity and Function in Adult Mice

(2014) Matthew J. Harms et al.   Cell Metabolism

KSRP Ablation Enhances Brown Fat Gene Program in White Adipose Tissue Through Reduced miR-150 Expression

(2014) C.-F. Chou et al.   DIABETES

MEF2 Transcription Factors Regulate Distinct Gene Programs in Mammalian Skeletal Muscle Differentiation

(2014) Nelsa L. Estrella et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KSRP and MicroRNA 145 Are Negative Regulators of Lipolysis in White Adipose Tissue

(2014) Y.-Y. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

HuR Regulates Alternative Splicing of the TRA2  Gene in Human Colon Cancer Cells under Oxidative Stress

(2014) Y. Akaike et al.   MOLECULAR AND CELLULAR BIOLOGY

Competition between target sites of regulators shapes post-transcriptional gene regulation

(2014) Marvin Jens et al.   NATURE REVIEWS GENETICS

Double-strand break repair deficiency in NONO knockout murine embryonic fibroblasts and compensation by spontaneous upregulation of the PSPC1 paralog

(2014) Shuyi Li et al.   NUCLEIC ACIDS RESEARCH

Brown fat fuel utilization and thermogenesis

(2014) Kristy L. Townsend et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

(2014) Maggie C. Y. Ng et al.   PLoS Genetics

Distinction of white, beige and brown adipocytes derived from mesenchymal stem cells

(2014) Anna Park   World Journal of Stem Cells

Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

(2013) S. Carobbio et al.   DIABETES

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

Role of Sam68 in Post-Transcriptional Gene Regulation

(2013) Flora Sánchez-Jiménez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A compendium of RNA-binding motifs for decoding gene regulation

(2013) Debashish Ray et al.   NATURE

Role of Alternative Polyadenylation during Adipogenic Differentiation: An In Silico Approach

(2013) Lucía Spangenberg et al.   PLoS One

Sam68 is a novel marker for aggressive neuroblastoma

(2013) Zhe Xu et al.   OncoTargets and Therapy

Pref-1, a Gatekeeper of Adipogenesis

(2013) Carolyn S. Hudak et al.   Frontiers in Endocrinology

Structural and biochemical characteristics of various white adipose tissue depots

(2012) A. Wronska et al.   Acta Physiologica

Functional and molecular insights into KSRP function in mRNA decay

(2012) Paola Briata et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Insulin-Like Growth Factor 2 in Development and Disease: A Mini-Review

(2012) Daniel Bergman et al.   GERONTOLOGY

The Sam68 STAR RNA-Binding Protein Regulates mTOR Alternative Splicing during Adipogenesis

(2012) Marc-Étienne Huot et al.   MOLECULAR CELL

The RNA Binding Protein SAM68 Transiently Localizes in the Chromatoid Body of Male Germ Cells and Influences Expression of Select MicroRNAs

(2012) Valeria Messina et al.   PLoS One

TNFα-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors

(2011) Sanhong Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HuR and myogenesis: Being in the right place at the right time

(2011) Christopher von Roretz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The RNA-binding protein Sam68 is a multifunctional player in human cancer

(2011) P. Bielli et al.   ENDOCRINE-RELATED CANCER

Interleukin-1 Activates Synthesis of Interleukin-6 by Interfering with a KH-type Splicing Regulatory Protein (KSRP)-dependent Translational Silencing Mechanism

(2011) Sonam Dhamija et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose tissue stem cells meet preadipocyte commitment: going back to the future

(2011) William P. Cawthorn et al.   JOURNAL OF LIPID RESEARCH

RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage

(2011) Weijun Dai et al.   NUCLEIC ACIDS RESEARCH

Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells

(2011) Maria Paola Paronetto et al.   NUCLEIC ACIDS RESEARCH

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation

(2010) P Beauchamp et al.   CELL DEATH AND DIFFERENTIATION

Distribution and Development of Brown Adipocytes in the Murine and Human Adipose Organ

(2010) Andrea Frontini et al.   Cell Metabolism

Role of the RNA-Binding Protein IMP-2 in Muscle Cell Motility

(2010) S. Boudoukha et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of C/EBPδ in the early stages of adipogenesis

(2009) Tomoaki Hishida et al.   BIOCHIMIE

FoxO1 Controls Insulin-dependent Adipose Triglyceride Lipase (ATGL) Expression and Lipolysis in Adipocytes

(2009) Partha Chakrabarti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

(2009) Michele Trabucchi et al.   NATURE

New developments in adipogenesis

(2009) Martina I. Lefterova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diverse molecular functions of Hu proteins

(2008) M. N. Hinman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Whitesnake/sfpq is required for cell survival and neuronal development in the zebrafish

(2008) Laura Anne Lowery et al.   DEVELOPMENTAL DYNAMICS

RBM4: A multifunctional RNA-binding protein

(2008) M. Andrea Markus et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY