Role of tumor microenvironment in cancer progression and therapeutic strategy
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of tumor microenvironment in cancer progression and therapeutic strategy
Authors
Keywords
-
Journal
Cancer Medicine
Volume 12, Issue 10, Pages 11149-11165
Publisher
Wiley
Online
2023-02-22
DOI
10.1002/cam4.5698
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Kinetic modeling: A tool for temperature shift and feeding optimization in cell culture process development
- (2022) Zheyu Wang et al. PROTEIN EXPRESSION AND PURIFICATION
- Impact of postal correspondence letters on participation in cancer screening: a rapid review
- (2021) Mafo Yakubu et al. PREVENTIVE MEDICINE
- Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice
- (2021) Se-Hoon Lee et al. Nature Microbiology
- Immune Checkpoint Inhibitors for the Treatment of Bladder Cancer
- (2021) Antonio Lopez-Beltran et al. Cancers
- Ablative Radiotherapy Reprograms the Tumor Microenvironment of a Pancreatic Tumor in Favoring the Immune Checkpoint Blockade Therapy
- (2021) Yu-Hung Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients
- (2021) Diwakar Davar et al. SCIENCE
- The Role of Tumor Microenvironment in Cancer Metastasis: Molecular Mechanisms and Therapeutic Opportunities
- (2021) Christiana M. Neophytou et al. Cancers
- The role of PD-L1 in the immune dysfunction that mediates hypoxia-induced multiple organ injury
- (2021) Yang Sun et al. Cell Communication and Signaling
- Clinical and therapeutic relevance of cancer-associated fibroblasts
- (2021) Yang Chen et al. Nature Reviews Clinical Oncology
- Metabolic modulation of tumours with engineered bacteria for immunotherapy
- (2021) Fernando P. Canale et al. NATURE
- The foundations of immune checkpoint blockade and the ipilimumab approval decennial
- (2021) Alan J. Korman et al. NATURE REVIEWS DRUG DISCOVERY
- Genetic Modification of Cytokine Signaling to Enhance Efficacy of CAR T Cell Therapy in Solid Tumors
- (2021) Navid Ghahri-Saremi et al. Frontiers in Immunology
- Gut Microbiota for Esophageal Cancer: Role in Carcinogenesis and Clinical Implications
- (2021) Jianfeng Zhou et al. Frontiers in Oncology
- Emerging targets for anticancer vaccination: PD-1
- (2021) J. Tobias et al. ESMO Open
- NK cells for cancer immunotherapy
- (2020) Noriko Shimasaki et al. NATURE REVIEWS DRUG DISCOVERY
- Modeling the Tumor Microenvironment and Pathogenic Signaling in Bone Sarcoma
- (2020) Eric R. Molina et al. TISSUE ENGINEERING PART B-REVIEWS
- Microenvironment-Dependent Gradient of CTL Exhaustion in the AE17sOVA Murine Mesothelioma Tumor Model
- (2020) Jennifer L. Hope et al. Frontiers in Immunology
- Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics
- (2020) Vinayaka Kotraiah et al. Frontiers in Immunology
- SnapShot: Cancer-Associated Fibroblasts
- (2020) Danielle Park et al. CELL
- Immune checkpoint signaling and cancer immunotherapy
- (2020) Xing He et al. CELL RESEARCH
- Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer
- (2020) Maria Paula Roberti et al. NATURE MEDICINE
- The human tumor microbiome is composed of tumor type–specific intracellular bacteria
- (2020) Deborah Nejman et al. SCIENCE
- CCN-Based Therapeutic Peptides Modify Pancreatic Ductal Adenocarcinoma Microenvironment and Decrease Tumor Growth in Combination with Chemotherapy
- (2020) Andrea Resovi et al. Cells
- Variation of PD-L1 expression in locally advanced cervical cancer following neoadjuvant chemotherapy
- (2020) Yun Liang et al. Diagnostic Pathology
- Non-coding RNAs shuttled via exosomes reshape the hypoxic tumor microenvironment
- (2020) Wenyu Wang et al. Journal of Hematology & Oncology
- Re-education of the Tumor Microenvironment With Targeted Therapies and Immunotherapies
- (2020) Shin Foong Ngiow et al. Frontiers in Immunology
- PD-1 Immune Checkpoint Blockade Promotes Therapeutic Cancer Vaccine to Eradicate Lung Cancer
- (2020) Pournima Kadam et al. Vaccines
- Research Status and Outlook of PD-1/PD-L1 Inhibitors for Cancer Therapy
- (2020) Leilei Ai et al. Drug Design Development and Therapy
- Dostarlimab in the treatment of recurrent or primary advanced endometrial cancer
- (2020) Lawrence Kasherman et al. Future Oncology
- Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients
- (2020) Erez N. Baruch et al. SCIENCE
- Cancer-associated fibroblasts and their influence on tumor immunity and immunotherapy
- (2020) Richard Lee Barrett et al. eLife
- Cancer Vaccines: Toward the Next Breakthrough in Cancer Immunotherapy
- (2020) Yuka Igarashi et al. Journal of Immunology Research
- The Intestinal Microbiota and Colorectal Cancer
- (2020) Yiwen Cheng et al. Frontiers in Immunology
- Tumor Microenvironment Uses a Reversible Reprogramming of Mesenchymal Stromal Cells to Mediate Pro-tumorigenic Effects
- (2020) Armel H. Nwabo Kamdje et al. Frontiers in Cell and Developmental Biology
- Myeloid-Derived Suppressor Cells: Facilitators of Cancer and Obesity-Induced Cancer
- (2020) Suzanne Ostrand-Rosenberg Annual Review of Cancer Biology-Series
- Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape
- (2019) Xianjie Jiang et al. Molecular Cancer
- Mechanisms of resistance to CAR T cell therapy
- (2019) Nirali N. Shah et al. Nature Reviews Clinical Oncology
- The microbiome, cancer, and cancer therapy
- (2019) Beth A. Helmink et al. NATURE MEDICINE
- Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non–small cell lung cancer
- (2019) Bo Gong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Targeting Tumor Microenvironment for Cancer Therapy
- (2019) Catarina Roma-Rodrigues et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Exosomes in cancer development, metastasis, and immunity
- (2019) Lin Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory
- (2019) Mauro Poggio et al. CELL
- Immune suppression by PD-L2 against spontaneous and treatment-related antitumor immunity
- (2019) Hiroyoshi Nishikawa et al. CLINICAL CANCER RESEARCH
- Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
- (2019) Ladan Mashouri et al. Molecular Cancer
- Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance
- (2019) Micol Eleonora Fiori et al. Molecular Cancer
- Development of the Inhibitors that Target the PD-1/PD-L1 Interaction—A Brief Look at Progress on Small Molecules, Peptides and Macrocycles
- (2019) Guzik et al. MOLECULES
- Profile of pembrolizumab in the treatment of patients with unresectable or metastatic urothelial carcinoma
- (2019) Junichi Inokuchi et al. Cancer Management and Research
- The Tumor Microenvironment Innately Modulates Cancer Progression
- (2019) Dominique C. Hinshaw et al. CANCER RESEARCH
- IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion
- (2019) Li-Chuan Chan et al. JOURNAL OF CLINICAL INVESTIGATION
- Combination of CTLA-4 and PD-1 blockers for treatment of cancer
- (2019) Anand Rotte JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Microenvironmental Regulation of Tumor Progression and Therapeutic Response in Brain Metastasis
- (2019) Michael Schulz et al. Frontiers in Immunology
- Gut microbiome affects the response to anti-PD-1 immunotherapy in patients with hepatocellular carcinoma
- (2019) Yi Zheng et al. Journal for ImmunoTherapy of Cancer
- Mechanically tunable coaxial electrospun models of YAP/TAZ mechanoresponse and IGF-1R activation in osteosarcoma
- (2019) Eric R. Molina et al. Acta Biomaterialia
- Immunity, Hypoxia and Metabolism - the ménage à trois of cancer: implications for immunotherapy
- (2019) Carla Riera-Domingo et al. PHYSIOLOGICAL REVIEWS
- Cemiplimab-rwlc as first and only treatment for advanced cutaneous squamous cell carcinoma
- (2019) Saqib R. Ahmed et al. Expert Review of Clinical Pharmacology
- Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges
- (2019) Muhammad Zaeem Noman et al. Cells
- Metabolic kinetic modeling provides insight into complex biological questions, but hurdles remain
- (2019) Jonathan Strutz et al. CURRENT OPINION IN BIOTECHNOLOGY
- Metabolic crosstalk in the breast cancer microenvironment
- (2019) Ana S. Dias et al. EUROPEAN JOURNAL OF CANCER
- Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironment
- (2019) Li Yang et al. Journal of Hematology & Oncology
- The role of exosomal PD-L1 in tumor progression and immunotherapy
- (2019) Feiting Xie et al. Molecular Cancer
- The structural features that distinguish PD-L2 from PD-L1 emerged in placental mammals
- (2019) Elliot A. Philips et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nivolumab in the treatment of microsatellite instability high metastatic colorectal cancer
- (2018) Amir Mehrvarz Sarshekeh et al. Future Oncology
- STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis
- (2018) Neibla Priego et al. NATURE MEDICINE
- Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges
- (2018) Dai Fukumura et al. Nature Reviews Clinical Oncology
- Tracking the fate of adoptively transferred myeloid-derived suppressor cells in the primary breast tumor microenvironment
- (2018) Jaclyn Sceneay et al. PLoS One
- The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients
- (2018) Vyara Matson et al. SCIENCE
- Houdini Tumor: Case Report and Literature Review of Pregnancy-Associated Meningioma
- (2018) Vikram Chakravarthy et al. World Neurosurgery
- Recent advances in CAR T-cell toxicity: Mechanisms, manifestations and management
- (2018) Jennifer N. Brudno et al. BLOOD REVIEWS
- Effects of tumor metabolic microenvironment on regulatory T cells
- (2018) Yi-an Wang et al. Molecular Cancer
- Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis
- (2018) Yinghong Wang et al. NATURE MEDICINE
- Product review: avelumab, an anti-PD-L1 antibody
- (2018) Julie M. Collins et al. Human Vaccines & Immunotherapeutics
- MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
- (2017) Daniel Yee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- New development in CAR-T cell therapy
- (2017) Zhenguang Wang et al. Journal of Hematology & Oncology
- Combined Radiotherapy and Anti–PD-L1 Antibody Synergistically Enhances Antitumor Effect in Non–Small Cell Lung Cancer
- (2017) Xiaomei Gong et al. Journal of Thoracic Oncology
- Prognostic significance of metabolic enzyme pyruvate kinase M2 in breast cancer
- (2017) Yiming Yang et al. MEDICINE
- Implications of the tumor immune microenvironment for staging and therapeutics
- (2017) Janis M Taube et al. MODERN PATHOLOGY
- Intra-tumor heterogeneity from a cancer stem cell perspective
- (2017) Pramudita R. Prasetyanti et al. Molecular Cancer
- Radiotherapy and immunotherapy: a beneficial liaison?
- (2017) Ralph R. Weichselbaum et al. Nature Reviews Clinical Oncology
- Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications
- (2017) Grant M. Fischer et al. Pigment Cell & Melanoma Research
- Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2
- (2017) Krzysztof M. Zak et al. STRUCTURE
- Metabolic Interactions in the Tumor Microenvironment
- (2017) Costas A. Lyssiotis et al. TRENDS IN CELL BIOLOGY
- Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment
- (2017) Binlong Chen et al. Theranostics
- Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9
- (2017) Jiangtao Ren et al. Protein & Cell
- Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment
- (2017) Irene Scarfò et al. Journal for ImmunoTherapy of Cancer
- Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy
- (2017) Seema Gupta et al. Frontiers in Oncology
- Pathomimetic cancer avatars for live-cell imaging of protease activity
- (2016) Kyungmin Ji et al. BIOCHIMIE
- Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade
- (2016) Haidong Tang et al. CANCER CELL
- Tumor microenvironment and cancer therapy resistance
- (2016) Yu Sun CANCER LETTERS
- Atezolizumab: A PD-L1–Blocking Antibody for Bladder Cancer
- (2016) Brant A. Inman et al. CLINICAL CANCER RESEARCH
- The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction
- (2016) Nicole E. Scharping et al. IMMUNITY
- Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape
- (2016) Meenakshi Hegde et al. JOURNAL OF CLINICAL INVESTIGATION
- IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma
- (2016) Salah-Eddine Lamhamedi-Cherradi et al. JNCI-Journal of the National Cancer Institute
- PKM2 and cancer: The function of PKM2 beyond glycolysis
- (2016) GAOCHAO DONG et al. Oncology Letters
- IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma
- (2016) Salah-Eddine Lamhamedi-Cherradi et al. JNCI-Journal of the National Cancer Institute
- Chemoradiation Increases PD-L1 Expression in Certain Melanoma and Glioblastoma Cells
- (2016) Anja Derer et al. Frontiers in Immunology
- The effect of environmental chemicals on the tumor microenvironment
- (2015) Stephanie C. Casey et al. CARCINOGENESIS
- Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
- (2015) James Larkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
- (2015) M. Vetizou et al. SCIENCE
- Increased complexity in carcinomas: Analyzing and modeling the interaction of human cancer cells with their microenvironment
- (2015) Mira Stadler et al. SEMINARS IN CANCER BIOLOGY
- Myeloid Expression of Adenosine A2A Receptor Suppresses T and NK Cell Responses in the Solid Tumor Microenvironment
- (2014) C. Cekic et al. CANCER RESEARCH
- PD-1 induction through TCR activation is partially regulated by endogenous TGF-β
- (2014) Raja Rekik et al. Cellular & Molecular Immunology
- Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor-Transduced Human T cells in Solid Tumors
- (2014) E. K. Moon et al. CLINICAL CANCER RESEARCH
- Consideration of GREB1 as a potential therapeutic target for hormone-responsive or endocrine-resistant cancers
- (2014) Kendra M Hodgkinson et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mast Cell Function
- (2014) Elaine Zayas Marcelino da Silva et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- MicroRNA-513 Regulates B7-H1 Translation and Is Involved in IFN- -Induced B7-H1 Expression in Cholangiocytes
- (2014) A.-Y. Gong et al. JOURNAL OF IMMUNOLOGY
- Curcumin Suppresses Crosstalk between Colon Cancer Stem Cells and Stromal Fibroblasts in the Tumor Microenvironment: Potential Role of EMT
- (2014) Constanze Buhrmann et al. PLoS One
- Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression
- (2014) J. L. Heinecke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Look back in anger – what clinical studies tell us about preclinical work
- (2014) Thomas Hartung ALTEX-Alternatives to Animal Experimentation
- Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment
- (2014) Theerawut Chanmee et al. Cancers
- Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer
- (2013) Krushna C. Patra et al. CANCER CELL
- Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors
- (2013) J. Duraiswamy et al. CANCER RESEARCH
- Three-dimensional spatial configuration of tumour cells confers resistance to chemotherapy independent of drug delivery
- (2013) Pamela H. S. Tan et al. Journal of Tissue Engineering and Regenerative Medicine
- Combinational Targeting Offsets Antigen Escape and Enhances Effector Functions of Adoptively Transferred T Cells in Glioblastoma
- (2013) Meenakshi Hegde et al. MOLECULAR THERAPY
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy
- (2013) Zakaria Grada et al. Molecular Therapy-Nucleic Acids
- Natural and Induced T Regulatory Cells in Cancer
- (2013) Dennis O. Adeegbe et al. Frontiers in Immunology
- The Insulin-Like Growth Factor System in Bone
- (2012) Masanobu Kawai et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- The development and immunosuppressive functions of CD4+ CD25+ FoxP3+ regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway
- (2012) Akio Ohta et al. Frontiers in Immunology
- Radiation-induced cell death mechanisms
- (2010) David Eriksson et al. TUMOR BIOLOGY
- Development of IGF-IR inhibitors in pediatric sarcomas
- (2009) E. Anders Kolb et al. Current Oncology Reports
- TGFβ in Cancer
- (2008) Joan Massagué CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started