Ablative Radiotherapy Reprograms the Tumor Microenvironment of a Pancreatic Tumor in Favoring the Immune Checkpoint Blockade Therapy

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

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Radiotherapy Both Promotes and Inhibits Myeloid-Derived Suppressor Cell Function: Novel Strategies for Preventing the Tumor-Protective Effects of Radiotherapy

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Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment

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Assessing the Magnitude of Immunogenic Cell Death Following Chemotherapy and Irradiation Reveals a New Strategy to Treat Pancreatic Cancer

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Gadolinium-doped iron oxide nanoparticles induced magnetic field hyperthermia combined with radiotherapy increases tumour response by vascular disruption and improved oxygenation

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Decline of Tumor Vascular Function as Assessed by Dynamic Contrast-Enhanced Magnetic Resonance Imaging Is Associated With Poor Responses to Radiation Therapy and Chemotherapy

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Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment

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Challenges of Using High-Dose Fractionation Radiotherapy in Combination Therapy

(2016) Ying-Chieh Yang et al.   Frontiers in Oncology

Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions

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Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial

(2015) Alexander M M Eggermont et al.   LANCET ONCOLOGY

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

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Nivolumab in Previously Untreated Melanoma without BRAF Mutation

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Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer

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Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer

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Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers

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Radiation Therapy-Induced Tumor Invasiveness Is Associated with SDF-1-Regulated Macrophage Mobilization and Vasculogenesis

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Novel Pancreatic Cancer Cell Lines Derived from Genetically Engineered Mouse Models of Spontaneous Pancreatic Adenocarcinoma: Applications in Diagnosis and Therapy

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Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

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Irradiation Promotes an M2 Macrophage Phenotype in Tumor Hypoxia

(2012) Chi-Shiun Chiang et al.   Frontiers in Oncology

Conditional survival in patients with pancreatic ductal adenocarcinoma resected with curative intent

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Tumor-secreted SDF-1 promotes glioma invasiveness and TAM tropism toward hypoxia in a murine astrocytoma model

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Normalization of the Vasculature for Treatment of Cancer and Other Diseases

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Neoadjuvant therapy may lead to successful surgical resection and improved survival in patients with borderline resectable pancreatic cancer

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Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

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Radiotherapy Decreases Vascular Density and Causes Hypoxia with Macrophage Aggregation in TRAMP-C1 Prostate Tumors

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Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4 Antibody

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Ineffective Vaccination against Solid Tumors Can Be Enhanced by Hematopoietic Cell Transplantation

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