Gut microbiome affects the response to anti-PD-1 immunotherapy in patients with hepatocellular carcinoma

Cancer statistics, 2018

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Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial

(2018) Andrew X Zhu et al.   LANCET ONCOLOGY

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

A metagenomic study of the gut microbiome in Behcet’s disease

(2018) Zi Ye et al.   Microbiome

Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

(2017) Anthony B El-Khoueiry et al.   LANCET

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Characterization of oral and gut microbiome temporal variability in hospitalized cancer patients

(2017) Jessica R. Galloway-Peña et al.   Genome Medicine

Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing

(2017) Chao Fang et al.   GigaScience

Methane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expression

(2016) Xu Zhang et al.   Scientific Reports

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

(2015) Saeed Shoaie et al.   Cell Metabolism

MetaPhlAn2 for enhanced metagenomic taxonomic profiling

(2015) Duy Tin Truong et al.   NATURE METHODS

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

The UCSC Genome Browser database: 2015 update

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The Long-Term Stability of the Human Gut Microbiota

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From meta-omics to causality: experimental models for human microbiome research

(2013) Joëlle V Fritz et al.   Microbiome

Measures of phylogenetic differentiation provide robust and complementary insights into microbial communities

(2012) Donovan H Parks et al.   ISME Journal

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

(2008) Ann-Lii Cheng et al.   LANCET ONCOLOGY