Tumor Microenvironment Uses a Reversible Reprogramming of Mesenchymal Stromal Cells to Mediate Pro-tumorigenic Effects
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Tumor Microenvironment Uses a Reversible Reprogramming of Mesenchymal Stromal Cells to Mediate Pro-tumorigenic Effects
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-11-19
DOI
10.3389/fcell.2020.545126
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Clonal ZEB1-driven mesenchymal transition promotes targetable oncologic anti-angiogenic therapy resistance
- (2020) Ankush Chandra et al. CANCER RESEARCH
- Mesenchymal stem cell‐derived CXCL16 promotes progression of gastric cancer cells by STAT3‐mediated expression of Ror1
- (2020) Taro Ikeda et al. CANCER SCIENCE
- Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer
- (2020) Teodora Costea et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Senescent mesenchymal stem cells remodel extracellular matrix driving breast cancer cells to a more-invasive phenotype
- (2020) Deepraj Ghosh et al. JOURNAL OF CELL SCIENCE
- Bone marrow niche-derived extracellular matrix-degrading enzymes influence the progression of B-cell acute lymphoblastic leukemia
- (2020) Divij Verma et al. LEUKEMIA
- Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment
- (2020) Chengxiang Xia et al. LEUKEMIA
- Extracellular Vesicles From Notch Activated Cardiac Mesenchymal Stem Cells Promote Myocyte Proliferation and Neovasculogenesis
- (2020) Wanling Xuan et al. Frontiers in Cell and Developmental Biology
- Tumor microenvironment complexity and therapeutic implications at a glance
- (2020) Roghayyeh Baghban et al. Cell Communication and Signaling
- ER stress activates immunosuppressive network: implications for aging and Alzheimer’s disease
- (2020) Antero Salminen et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Revisiting Cancer Stem Cells as the Origin of Cancer-Associated Cells in the Tumor Microenvironment: A Hypothetical View from the Potential of iPSCs
- (2020) Amira Osman et al. Cancers
- Extracellular Adenosine promotes cell migration/invasion of Glioblastoma Stem-like Cells through A3 Adenosine Receptor activation under Hypoxia
- (2019) Ángelo Torres et al. CANCER LETTERS
- Activation of IGF/IGF-IR signaling pathway fails to induce epithelial-mesenchymal transition in pancreatic cancer cells
- (2019) E.P. Kopantzev et al. PANCREATOLOGY
- BM-MSCs-derived ECM modifies multiple myeloma phenotype and drug response in a source-dependent manner
- (2019) Amjd Ibraheem et al. Translational Research
- Effects of Gastric Cancer Cell-Derived Exosomes on the Immune Regulation of Mesenchymal Stem Cells by the NF-kB Signaling Pathway
- (2019) Yamei Shen et al. STEM CELLS AND DEVELOPMENT
- Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment
- (2019) Luke Bu et al. ONCOGENE
- Isolation and characterization of patient-derived CNS metastasis-associated stromal cell lines
- (2019) Ben Yi Tew et al. ONCOGENE
- The effects of adipose-derived stem cells on CD133-expressing bladder cancer cells
- (2019) Malgorzata Maj et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Hypoxia-induced cancer stemness acquisition is associated with CXCR4 activation by its aberrant promoter demethylation
- (2019) Nahyeon Kang et al. BMC CANCER
- Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression
- (2019) Robert M. Hughes et al. CANCER RESEARCH
- The investigation of immunomodulatory effects of adipose tissue mesenchymal stem cell educated macrophages on the CD4 T cells
- (2019) Rabia Bilge Özgül Özdemir et al. IMMUNOBIOLOGY
- Encapsulated human mesenchymal stem cells (eMSCs) as a novel anti-cancer agent targeting breast cancer stem cells: Development of 3D primed therapeutic MSCs
- (2019) Saurabh Mandal et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- A 17 gene panel for non‐small‐cell lung cancer prognosis identified through integrative epigenomic‐transcriptomic analyses of hypoxia‐induced epithelial–mesenchymal transition
- (2019) Yue‐Lei Chen et al. Molecular Oncology
- Primary lung cancer samples cultured under microenvironment-mimetic conditions enrich for mesenchymal stem-like cells that promote metastasis
- (2019) Douglas Saforo et al. Scientific Reports
- Gene signatures of quiescent glioblastoma cells reveal mesenchymal shift and interactions with niche microenvironment
- (2019) Rut Tejero et al. EBioMedicine
- TGFβ1 is essential for MSCs-CAFs differentiation and promotes HCT116 cells migration and invasion via JAK/STAT3 signaling
- (2019) Hao-Xiang Tan et al. OncoTargets and Therapy
- Human bone marrow-derived mesenchymal stem cell-secreted exosomes overexpressing microRNA-34a ameliorate glioblastoma development via down-regulating MYCN
- (2019) Bin Wang et al. CELLULAR ONCOLOGY
- Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis
- (2019) Yasuyuki Mizutani et al. CANCER RESEARCH
- The enhancement of glycolysis regulates pancreatic cancer metastasis
- (2019) Jinshou Yang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- More Than an Adipokine: The Complex Roles of Chemerin Signaling in Cancer
- (2019) Kerry B. Goralski et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Anti-tumor effects of engineered mesenchymal stem cells in colon cancer model
- (2019) Jianying Yang et al. Cancer Management and Research
- The Flick of a Switch: Conferring Survival Advantage to Breast Cancer Stem Cells Through Metabolic Plasticity
- (2019) Hayley R. Walsh et al. Frontiers in Oncology
- Cellular senescence induced by S100A9 in mesenchymal stromal cells through NLRP3 inflammasome activation
- (2019) Lei Shi et al. Aging-US
- Fusion of macrophages promotes breast cancer cell proliferation, migration and invasion through activating epithelial-mesenchymal transition and Wnt/β-catenin signaling pathway
- (2019) Li-Na Zhang et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Mesenchymal stem cells co-cultured with colorectal cancer cells showed increased invasive and proliferative abilities due to its altered p53/TGF-β1 levels
- (2019) In-Rok Oh et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Low-dose photodynamic therapy promotes angiogenic potential and increases immunogenicity of human mesenchymal stromal cells
- (2019) Olga O. Udartseva et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination
- (2019) Juan-Jose Garcés et al. LEUKEMIA
- Integrin αvβ3-Mediated Effects of Thyroid Hormones on Mesenchymal Stem Cells in Tumor Angiogenesis
- (2019) Kathrin A. Schmohl et al. THYROID
- Paradoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth
- (2019) Nhat D. Quach et al. Scientific Reports
- Melanoma-Derived Exosomes Induce PD-1 Overexpression and Tumor Progression via Mesenchymal Stem Cell Oncogenic Reprogramming
- (2019) Edina Gyukity-Sebestyén et al. Frontiers in Immunology
- Subcutaneous and Visceral Adipose-Derived Mesenchymal Stem Cells: Commonality and Diversity
- (2019) Andreas Ritter et al. Cells
- Protective effects of eicosapentaenoic acid in adipocyte-breast cancer cell cross talk
- (2019) Arwa Al-Jawadi et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Cirrhotic Human Liver Extracellular Matrix 3D Scaffolds Promote Smad-Dependent TGF-β1 Epithelial Mesenchymal Transition
- (2019) Giuseppe Mazza et al. Cells
- Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases
- (2018) Yufang Shi et al. Nature Reviews Nephrology
- Visfatin alters the cytokine and matrix-degrading enzyme profile during osteogenic and adipogenic MSC differentiation
- (2018) L. Tsiklauri et al. OSTEOARTHRITIS AND CARTILAGE
- Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner
- (2018) Manabu Kato et al. ONCOGENE
- Modification of the bone marrow MSC population in a xenograft model of early multiple myeloma
- (2018) Jessica L. Berlier et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Acute myeloid leukemia induces pro-tumoral p16INK4a driven senescence in the bone marrow microenvironment
- (2018) Amina M Abdul-Aziz et al. BLOOD
- Microenvironment in neuroblastoma: isolation and characterization of tumor-derived mesenchymal stromal cells
- (2018) Gloria Pelizzo et al. BMC CANCER
- Mesenchymal stem cells participate in oral mucosa carcinogenesis by regulating T cell proliferation
- (2018) Yichen Chen et al. CLINICAL IMMUNOLOGY
- Development of extracellular matrix supported 3D culture of renal cancer cells and renal cancer stem cells
- (2018) Kamila Maliszewska-Olejniczak et al. CYTOTECHNOLOGY
- MiR-141-3p suppresses gastric cancer induced transition of normal fibroblast and BMSC to cancer-associated fibroblasts via targeting STAT4
- (2018) Jun Xiao et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- CXCL8 derived from mesenchymal stromal cells supports survival and proliferation of acute myeloid leukemia cells through the PI3K/AKT pathway
- (2018) Jingying Cheng et al. FASEB JOURNAL
- CCR5 antagonism by maraviroc inhibits Hodgkin lymphoma microenvironment interactions and xenograft growth
- (2018) Naike Casagrande et al. HAEMATOLOGICA
- Alteration of cellular and immune-related properties of bone marrow mesenchymal stem cells and macrophages by K562 chronic myeloid leukemia cell derived exosomes
- (2018) Nazli Jafarzadeh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Hypoxia-driven paracrine osteopontin/integrin αvβ3 signaling promotes pancreatic cancer cell epithelial-mesenchymal transition and cancer stem cell-like properties by modulating forkhead box protein M1
- (2018) Junyu Cao et al. Molecular Oncology
- The obese adipose tissue microenvironment in cancer development and progression
- (2018) Daniela F. Quail et al. Nature Reviews Endocrinology
- Adipose stromal cell targeting suppresses prostate cancer epithelial-mesenchymal transition and chemoresistance
- (2018) Fei Su et al. ONCOGENE
- Macrophage-mediated transfer of cancer-derived components to stromal cells contributes to establishment of a pro-tumor microenvironment
- (2018) Michinobu Umakoshi et al. ONCOGENE
- EGFL6 promotes breast cancer by simultaneously enhancing cancer cell metastasis and stimulating tumor angiogenesis
- (2018) Jingnan An et al. ONCOGENE
- Tumor-infiltrating mesenchymal stem cells: Drivers of the immunosuppressive tumor microenvironment in prostate cancer?
- (2018) Timothy E. Krueger et al. PROSTATE
- Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer
- (2018) Yeela Shamai et al. STEM CELLS
- Ovarian Carcinoma-Associated Mesenchymal Stem Cells Arise from Tissue-Specific Normal Stroma
- (2018) Lan G. Coffman et al. STEM CELLS
- Breast Tumor Microenvironment Can Transform Naïve Mesenchymal Stem Cells into Tumor Forming Cells in Nude Mice
- (2018) Philipp M Wörner et al. STEM CELLS AND DEVELOPMENT
- The Reparative Effects of Human Adipose-Derived Mesenchymal Stem Cells in the Chemotherapy-Damaged Thymus
- (2018) Ying Zhan et al. STEM CELLS AND DEVELOPMENT
- Microvesicles derived from human bone marrow mesenchymal stem cells promote U2OS cell growth under hypoxia: the role of PI3K/AKT and HIF-1α
- (2018) Shanshan Lin et al. Human Cell
- Knockdown of long non-coding RNA linc-ITGB1 inhibits cancer stemness and epithelial-mesenchymal transition by reducing the expression of Snail in non-small cell lung cancer
- (2018) Lili Guo et al. Thoracic Cancer
- Mesenchymal Stem Cell Administration Attenuates Colon Cancer Progression by Modulating the Immune Component within the Colorectal Tumor Microenvironment
- (2018) Sabine François et al. Stem Cells Translational Medicine
- A Promising Tool in Retina Regeneration: Current Perspectives and Challenges When Using Mesenchymal Progenitor Stem Cells in Veterinary and Human Ophthalmological Applications
- (2017) Anna Cislo-Pakuluk et al. Stem Cell Reviews and Reports
- The reverse Warburg effect is likely to be an Achilles’ heel of cancer that can be exploited for cancer therapy
- (2017) Yaojie Fu et al. Oncotarget
- A Promising Tool in Retina Regeneration: Current Perspectives and Challenges When Using Mesenchymal Progenitor Stem Cells in Veterinary and Human Ophthalmological Applications
- (2017) Anna Cislo-Pakuluk et al. Stem Cell Reviews and Reports
- A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression
- (2017) María de la Luz García-Hernández et al. Frontiers in Immunology
- Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation
- (2016) Neil M. Iyengar et al. JOURNAL OF CLINICAL ONCOLOGY
- MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC
- (2016) Sara Rolandsson Enes et al. Scientific Reports
- HIF-1 at the crossroads of hypoxia, inflammation, and cancer
- (2015) Kuppusamy Balamurugan INTERNATIONAL JOURNAL OF CANCER
- Acquisition of new tumor cell properties by MSC-derived exosomes
- (2015) YUANYUAN YANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Anti-Inflammatory/Tissue Repair Macrophages Enhance the Cartilage-Forming Capacity of Human Bone Marrow-Derived Mesenchymal Stromal Cells
- (2015) Sergio B. Sesia et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Mesenchymal Progenitors Expressing TRAIL Induce Apoptosis in Sarcomas
- (2015) Giulia Grisendi et al. STEM CELLS
- Warburg Effect or Reverse Warburg Effect? A Review of Cancer Metabolism
- (2015) Xiao Dong Xu et al. Oncology Research and Treatment
- Signaling pathways in breast cancer: Therapeutic targeting of the microenvironment
- (2014) Armel Herve Nwabo Kamdje et al. CELLULAR SIGNALLING
- Transplantation of SIRT1-engineered aged mesenchymal stem cells improves cardiac function in a rat myocardial infarction model
- (2014) Xianbao Liu et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- In vitro biosafety profile evaluation of multipotent mesenchymal stem cells derived from the bone marrow of sarcoma patients
- (2014) Enrico Lucarelli et al. Journal of Translational Medicine
- Obesity and cancer—mechanisms underlying tumour progression and recurrence
- (2014) Jiyoung Park et al. Nature Reviews Endocrinology
- Equine mesenchymal stem cells from bone marrow, adipose tissue and umbilical cord: immunophenotypic characterization and differentiation potential
- (2014) Danielle Barberini et al. Stem Cell Research & Therapy
- Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor-A signaling pathway
- (2013) Nan Wang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Mesenchymal stem cell secreted platelet derived growth factor exerts a pro-migratory effect on resident Cardiac Atrial appendage Stem Cells
- (2013) Severina Windmolders et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mesenchymal stem cells protect podocytes from apoptosis induced by high glucose via secretion of epithelial growth factor
- (2013) Diangeng Li et al. Stem Cell Research & Therapy
- Normal hematopoiesis and hematologic malignancies: Role of canonical Wnt signaling pathway and stromal microenvironment
- (2012) Paul Faustin Seke Etet et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells
- (2011) A. H. Nwabo Kamdje et al. BLOOD
- Interaction of human adipose tissue-derived mesenchymal stromal cells with breast cancer cells
- (2011) L. KUCEROVA et al. NEOPLASMA
- The Warburg Effect in Leukemia-Stroma Cocultures Is Mediated by Mitochondrial Uncoupling Associated with Uncoupling Protein 2 Activation
- (2008) I. Samudio et al. CANCER RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started