Alternative lung cell model systems for toxicology testing strategies: Current knowledge and future outlook
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Alternative lung cell model systems for toxicology testing strategies: Current knowledge and future outlook
Authors
Keywords
-
Journal
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2023-01-02
DOI
10.1016/j.semcdb.2022.12.006
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Lung epithelial cells interact with immune cells and bacteria to shape the microenvironment in tuberculosis
- (2022) Amy M de Waal et al. THORAX
- Dynamic Fluid Flow Exacerbates the (Pro-)Inflammatory Effects of Aerosolised Engineered Nanomaterials In Vitro
- (2022) Kirsty Meldrum et al. Nanomaterials
- Inter-laboratory variability of A549 epithelial cells grown under submerged and air-liquid interface conditions
- (2021) Hana Barosova et al. TOXICOLOGY IN VITRO
- Robotic fluidic coupling and interrogation of multiple vascularized organ chips
- (2020) Richard Novak et al. Nature Biomedical Engineering
- An Alternative Perspective towards Reducing the Risk of Engineered Nanomaterials to Human Health
- (2020) Martin J. D. Clift et al. Small
- Long‐term expanding human airway organoids for disease modeling
- (2019) Norman Sachs et al. EMBO JOURNAL
- Generation of lung organoids from human pluripotent stem cells in vitro
- (2019) Alyssa J. Miller et al. Nature Protocols
- Using a 3D collagen matrix to deliver respiratory progenitor cells to decellularized trachea in vivo
- (2019) Nick Hamilton et al. TISSUE ENGINEERING PART C-METHODS
- Multivascular networks and functional intravascular topologies within biocompatible hydrogels
- (2019) Bagrat Grigoryan et al. SCIENCE
- 3D bioprinting for lungs and hollow organs
- (2019) Zachary Galliger et al. Translational Research
- Bioengineered in Vitro Tissue Model of Fibroblast Activation for Modeling Pulmonary Fibrosis
- (2019) Aswin Sundarakrishnan et al. ACS Biomaterials-Science & Engineering
- Cellular crosstalk in the development and regeneration of the respiratory system
- (2019) Jarod A. Zepp et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening
- (2019) Minsuh Kim et al. Nature Communications
- Identification of urban particulate matter-induced disruption of human respiratory mucosa integrity using whole transcriptome analysis and organ-on-a chip
- (2019) Junhyoung Byun et al. Journal of Biological Engineering
- Bioengineered Lungs: A Challenge and An Opportunity
- (2018) Ramon Farré et al. ARCHIVOS DE BRONCONEUMOLOGIA
- Epithelial-mesenchymal crosstalk influences cellular behavior in a 3D alveolus-fibroblast model system
- (2018) Katherine J.R. Lewis et al. BIOMATERIALS
- Biomimetics of the pulmonary environment in vitro: A microfluidics perspective
- (2018) Janna Tenenbaum-Katan et al. Biomicrofluidics
- A bioinspired microfluidic model of liquid plug-induced mechanical airway injury
- (2018) Joseph W. Song et al. Biomicrofluidics
- 3D Bioprinted Artificial Trachea with Epithelial Cells and Chondrogenic-Differentiated Bone Marrow-Derived Mesenchymal Stem Cells
- (2018) Sang-Woo Bae et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Microfluidic lung airway-on-a-chip with arrayable suspended gels for studying epithelial and smooth muscle cell interactions
- (2018) Mouhita Humayun et al. LAB ON A CHIP
- Long-term Engraftment Promotes Differentiation of Alveolar Epithelial Cells from Human Embryonic Stem Cells Derived Lung Organoids
- (2018) Yong Chen et al. STEM CELLS AND DEVELOPMENT
- Reconstituting Mouse Lungs with Conditionally Reprogrammed Human Bronchial Epithelial Cells
- (2018) Ryan LaRanger et al. TISSUE ENGINEERING PART A
- Organ-Derived Decellularized Extracellular Matrix: A Game Changer for Bioink Manufacturing?
- (2018) Deepak Choudhury et al. TRENDS IN BIOTECHNOLOGY
- Scaffold-free trachea regeneration by tissue engineering with bio-3D printing†
- (2018) Daisuke Taniguchi et al. Interactive Cardiovascular and Thoracic Surgery
- Bioengineered Lungs: A Challenge and An Opportunity
- (2018) Ramon Farré et al. ARCHIVOS DE BRONCONEUMOLOGIA
- Engineering of Removing Sacrificial Materials in 3D-Printed Microfluidics
- (2018) Pengju Yin et al. Micromachines
- Modelling Cryptosporidium infection in human small intestinal and lung organoids
- (2018) Inha Heo et al. Nature Microbiology
- 3D-Printed Microfluidic Devices for Materials Science
- (2018) Moien Alizadehgiashi et al. Advanced Materials Technologies
- Bioengineering strategies to accelerate stem cell therapeutics
- (2018) Christopher M. Madl et al. NATURE
- Progress and potential in organoid research
- (2018) Giuliana Rossi et al. NATURE REVIEWS GENETICS
- Optimization of cell-laden bioinks for 3D bioprinting and efficient infection with influenza A virus
- (2018) Johanna Berg et al. Scientific Reports
- Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening
- (2018) Roger Y. Tam et al. ADVANCED MATERIALS
- A Fully Automated High-Throughput Bioreactor System for Lung Regeneration
- (2018) Daniel E. Gorman et al. TISSUE ENGINEERING PART C-METHODS
- Synthesis and Properties of Gelatin Methacryloyl (GelMA) Hydrogels and Their Recent Applications in Load-Bearing Tissue
- (2018) Mingyue Sun et al. Polymers
- Leveraging proteomics to compare submerged versus air-liquid interface carbon nanotube exposure to a 3D lung cell model
- (2018) G. Hilton et al. TOXICOLOGY IN VITRO
- A 3-dimensional bioprinted tracheal segment implant pilot study: Rabbit tracheal resection with graft implantation
- (2018) Rachel Kaye et al. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
- Symmetry-breaking in branching epithelia: cells on micro-patterns under flow challenge the hypothesis of positive feedback by a secreted autocrine inhibitor of motility
- (2017) Kimberly C. Martin et al. JOURNAL OF ANATOMY
- Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells
- (2017) Finn Hawkins et al. JOURNAL OF CLINICAL INVESTIGATION
- Organ-on-a-chip devices advance to market
- (2017) Boyang Zhang et al. LAB ON A CHIP
- A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control
- (2017) J. R. Coppeta et al. LAB ON A CHIP
- Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function
- (2017) Olivier Y. F. Henry et al. LAB ON A CHIP
- An overview of additive manufacturing (3D printing) for microfabrication
- (2017) Bharat Bhushan et al. MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS
- A three-dimensional model of human lung development and disease from pluripotent stem cells
- (2017) Ya-Wen Chen et al. NATURE CELL BIOLOGY
- Long-term expansion of alveolar stem cells derived from human iPS cells in organoids
- (2017) Yuki Yamamoto et al. NATURE METHODS
- Microbial volatile communication in human organotypic lung models
- (2017) Layla J. Barkal et al. Nature Communications
- Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro
- (2017) Bryan A. Hassell et al. Cell Reports
- Development and validation of a 3D-printed model of the ostiomeatal complex and frontal sinus for endoscopic sinus surgery training
- (2017) Abdulaziz S. Alrasheed et al. International Forum of Allergy & Rhinology
- Human Pulmonary 3D Models For Translational Research
- (2017) Katja Zscheppang et al. Biotechnology Journal
- Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality
- (2017) Vanessa Neuhaus et al. Journal of Occupational Medicine and Toxicology
- Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture
- (2017) Patrick A. Link et al. Jove-Journal of Visualized Experiments
- Electrospun Decellularized Lung Matrix Scaffold for Airway Smooth Muscle Culture
- (2017) Bethany M. Young et al. ACS Biomaterials-Science & Engineering
- Electrospun Decellularized Lung Matrix Scaffold for Airway Smooth Muscle Culture
- (2017) Bethany M. Young et al. ACS Biomaterials Science & Engineering
- Bi-functional oxidized dextran–based hydrogel inducing microtumors: An in vitro three-dimensional lung tumor model for drug toxicity assays
- (2017) Dhaval Kedaria et al. Journal of Tissue Engineering
- Fast-track development of an in vitro 3D lung/immune cell model to study Aspergillus infections
- (2017) P. Chandorkar et al. Scientific Reports
- Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform
- (2017) Aleksander Skardal et al. Scientific Reports
- Bioreactors for tissue engineering: An update
- (2016) Junjie Zhao et al. BIOCHEMICAL ENGINEERING JOURNAL
- 3D bioprinting for engineering complex tissues
- (2016) Christian Mandrycky et al. BIOTECHNOLOGY ADVANCES
- Giving new life to old lungs: methods to produce and assess whole human paediatric bioengineered lungs
- (2016) Joan E. Nichols et al. Journal of Tissue Engineering and Regenerative Medicine
- Organoids as an in vitro model of human development and disease
- (2016) Aliya Fatehullah et al. NATURE CELL BIOLOGY
- Dual flow bioreactor with ultrathin microporous TEER sensing membrane for evaluation of nanoparticle toxicity
- (2016) Tommaso Sbrana et al. SENSORS AND ACTUATORS B-CHEMICAL
- A Comparison of Rodent and Nonrodent Laryngeal and Tracheal Bifurcation Sensitivities in Inhalation Toxicity Studies and Their Relevance for Human Exposure
- (2016) Vasanthi Mowat et al. TOXICOLOGIC PATHOLOGY
- Towards Single-Step Biofabrication of Organs on a Chip via 3D Printing
- (2016) Stephanie Knowlton et al. TRENDS IN BIOTECHNOLOGY
- Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling
- (2016) Dan C. Wilkinson et al. Stem Cells Translational Medicine
- Pluripotent Stem Cells: Current Understanding and Future Directions
- (2016) Antonio Romito et al. Stem Cells International
- A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
- (2016) Rami Fishler et al. Jove-Journal of Visualized Experiments
- Directed Induction of Functional Multi-ciliated Cells in Proximal Airway Epithelial Spheroids from Human Pluripotent Stem Cells
- (2016) Satoshi Konishi et al. Stem Cell Reports
- Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip
- (2016) Kambez H. Benam et al. Cell Systems
- Airway Epithelial Cell Cilia and Obstructive Lung Disease
- (2016) Asma Yaghi et al. Cells
- 3D Reconstruction of the Human Airway Mucosa In Vitro as an Experimental Model to Study NTHi Infections
- (2016) Pasquale Marrazzo et al. PLoS One
- A 3D Poly(ethylene glycol)-based Tumor Angiogenesis Model to Study the Influence of Vascular Cells on Lung Tumor Cell Behavior
- (2016) Laila C. Roudsari et al. Scientific Reports
- Reprint of: Extracellular matrix as a biological scaffold material: Structure and function
- (2015) Stephen F. Badylak et al. Acta Biomaterialia
- Cilia Dysfunction in Lung Disease
- (2015) Ann E. Tilley et al. Annual Review of Physiology
- Numerical investigation of inspiratory airflow in a realistic model of the human tracheobronchial airways and a comparison with experimental results
- (2015) Jakub Elcner et al. Biomechanics and Modeling in Mechanobiology
- Microfluidic 3D cell culture: from tools to tissue models
- (2015) Vincent van Duinen et al. CURRENT OPINION IN BIOTECHNOLOGY
- A lung-on-a-chip array with an integrated bio-inspired respiration mechanism
- (2015) Andreas O. Stucki et al. LAB ON A CHIP
- Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance
- (2015) Timothy J. Keane et al. METHODS
- Engineering pulmonary vasculature in decellularized rat and human lungs
- (2015) Xi Ren et al. NATURE BIOTECHNOLOGY
- Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro
- (2015) Kambez H Benam et al. NATURE METHODS
- The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells
- (2015) Sarah X L Huang et al. Nature Protocols
- Development of a Bronchial Wall Model: Triple Culture on a Decellularized Porcine Trachea
- (2015) Esther Melo et al. TISSUE ENGINEERING PART C-METHODS
- Three cheers for the goblet cell: maintaining homeostasis in mucosal epithelia
- (2015) Heather A. McCauley et al. TRENDS IN MOLECULAR MEDICINE
- Particle dynamics and deposition in true-scale pulmonary acinar models
- (2015) Rami Fishler et al. Scientific Reports
- Bioprocessing strategies for the large-scale production of human mesenchymal stem cells: a review
- (2015) Krishna M. Panchalingam et al. Stem Cell Research & Therapy
- Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung
- (2015) Henry Danahay et al. Cell Reports
- In vitro generation of human pluripotent stem cell derived lung organoids
- (2015) Briana R Dye et al. eLife
- Engineering an in vitro air-blood barrier by 3D bioprinting
- (2015) Lenke Horváth et al. Scientific Reports
- A novel dual-flow bioreactor simulates increased fluorescein permeability in epithelial tissue barriers
- (2014) Serena Giusti et al. Biotechnology Journal
- Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis
- (2014) Joo-Hyeon Lee et al. CELL
- Human Pluripotent Stem Cell Culture: Considerations for Maintenance, Expansion, and Therapeutics
- (2014) Kevin G. Chen et al. Cell Stem Cell
- Branching morphogenesis of immortalized human bronchial epithelial cells in three-dimensional culture
- (2014) Aadil Kaisani et al. DIFFERENTIATION
- Medical nanoparticles for next generation drug delivery to the lungs
- (2014) S. H. van Rijt et al. EUROPEAN RESPIRATORY JOURNAL
- Strategies for Whole Lung Tissue Engineering
- (2014) Elizabeth A. Calle et al. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
- The potential of microfluidic lung epithelial wounding: towards in vivo-like alveolar microinjuries
- (2014) M. Felder et al. Integrative Biology
- Bioprinting Technology: A Current State-of-the-Art Review
- (2014) Amer B. Dababneh et al. JOURNAL OF MANUFACTURING SCIENCE AND ENGINEERING-TRANSACTIONS OF THE ASME
- A biomimetic multicellular model of the airways using primary human cells
- (2014) Katelyn L. Sellgren et al. LAB ON A CHIP
- Engineered autologous cartilage tissue for nasal reconstruction after tumour resection: an observational first-in-human trial
- (2014) Ilario Fulco et al. LANCET
- Immunocompetent 3D Model of Human Upper Airway for Disease Modeling and In Vitro Drug Evaluation
- (2014) Helen Harrington et al. MOLECULAR PHARMACEUTICS
- Microfluidic organs-on-chips
- (2014) Sangeeta N Bhatia et al. NATURE BIOTECHNOLOGY
- 3D bioprinting of tissues and organs
- (2014) Sean V Murphy et al. NATURE BIOTECHNOLOGY
- IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells
- (2014) T. Tadokoro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Organogenesis in a dish: Modeling development and disease using organoid technologies
- (2014) M. A. Lancaster et al. SCIENCE
- Alveolar epithelial differentiation of human induced pluripotent stem cells in a rotating bioreactor
- (2013) Mahboobe Ghaedi et al. BIOMATERIALS
- Epithelial Injury and Repair in Airways Diseases
- (2013) Christopher L. Grainge et al. CHEST
- Stem cell engineering in bioreactors for large-scale bioprocessing
- (2013) Ning Liu et al. ENGINEERING IN LIFE SCIENCES
- Acinus-on-a-chip: A microfluidic platform for pulmonary acinar flows
- (2013) Rami Fishler et al. JOURNAL OF BIOMECHANICS
- Type 2 alveolar cells are stem cells in adult lung
- (2013) Christina E. Barkauskas et al. JOURNAL OF CLINICAL INVESTIGATION
- Live human nasal epithelial cells (hNECs) on chip for in vitro testing of gaseous formaldehyde toxicity via airway delivery
- (2013) Wei Wang et al. LAB ON A CHIP
- In vitrotoxicological screening of nanoparticles on primary human endothelial cells and the role of flow in modulating cell response
- (2013) Nadia Ucciferri et al. Nanotoxicology
- Efficient generation of lung and airway epithelial cells from human pluripotent stem cells
- (2013) Sarah X L Huang et al. NATURE BIOTECHNOLOGY
- Marine Collagen Scaffolds for Nasal Cartilage Repair: Prevention of Nasal Septal Perforations in a New Orthotopic Rat Model Using Tissue Engineering Techniques
- (2013) Christian Bermueller et al. TISSUE ENGINEERING PART A
- Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells
- (2012) Tyler A. Longmire et al. Cell Stem Cell
- Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs
- (2012) Hongmei Mou et al. Cell Stem Cell
- A short history of the toxicology of inhaled particles
- (2012) Ken Donaldson et al. Particle and Fibre Toxicology
- A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity
- (2012) Anna Astashkina et al. PHARMACOLOGY & THERAPEUTICS
- A Role for Mesenchyme Dynamics in Mouse Lung Branching Morphogenesis
- (2012) Pierre Blanc et al. PLoS One
- A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice
- (2012) Dongeun Huh et al. Science Translational Medicine
- Airway Epithelial Progenitors Are Region Specific and Show Differential Responses to Bleomycin-Induced Lung Injury
- (2012) Huaiyong Chen et al. STEM CELLS
- Comparison of Methods for Whole-Organ Decellularization in Tissue Engineering of Bioartificial Organs
- (2012) Ming He et al. TISSUE ENGINEERING PART B-REVIEWS
- An overview of tissue and whole organ decellularization processes
- (2011) Peter M. Crapo et al. BIOMATERIALS
- Notch-Dependent Differentiation of Adult Airway Basal Stem Cells
- (2011) Jason R. Rock et al. Cell Stem Cell
- Epithelial cells and airway diseases
- (2011) David Proud et al. IMMUNOLOGICAL REVIEWS
- Influence of particle size on regional lung deposition – What evidence is there?
- (2011) Thiago C. Carvalho et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Development of a realistic human airway model
- (2011) Frantisek Lizal et al. PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE
- Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung
- (2011) Sebastian G. Klein et al. TOXICOLOGY IN VITRO
- Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling
- (2010) J. R. Rock et al. Disease Models & Mechanisms
- Soft lithography for micro- and nanoscale patterning
- (2010) Dong Qin et al. Nature Protocols
- Pulmonary Surfactant Pathophysiology: Current Models and Open Questions
- (2010) Jesús Perez-Gil et al. PHYSIOLOGY
- Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung
- (2010) J. L. McQualter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reconstituting Organ-Level Lung Functions on a Chip
- (2010) D. Huh et al. SCIENCE
- Hydrogels as extracellular matrix mimics for 3D cell culture
- (2009) Mark W. Tibbitt et al. BIOTECHNOLOGY AND BIOENGINEERING
- Anatomy, pathology, and physiology of the tracheobronchial tree: Emphasis on the distal airways
- (2009) Dallas M. Hyde et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Breakdown in epithelial barrier function in patients with asthma: Identification of novel therapeutic approaches
- (2009) Emily J. Swindle et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Basal cells as stem cells of the mouse trachea and human airway epithelium
- (2009) J. R. Rock et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Simplified cell culture method for the diagnosis of atypical primary ciliary dyskinesia
- (2009) M Pifferi et al. THORAX
- Inhaled nanoparticles—A current review
- (2008) Wei Yang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Clinical transplantation of a tissue-engineered airway
- (2008) Paolo Macchiarini et al. LANCET
- Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model
- (2007) Alice A. Tomei et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started