Fluorinated and Non-Fluorinated 1,4-Diarylpyrazoles via MnO2-Mediated Mechanochemical Deacylative Oxidation of 5-Acylpyrazolines

Evaluation of Substituted Pyrazole-Based Kinase Inhibitors in One Decade (2011–2020): Current Status and Future Prospects

(2022) Mohammed I. El-Gamal et al.   MOLECULES

Quadruple Functionalized Pyrazole Pharmacophores via One‐pot Regioselective [3 + 2] Cycloaddition of Fluorinated Nitrile Imines and Dicyanoalkenes

(2022) Yin Zhou et al.   Chemistry-An Asian Journal

Trifluoromethylated Pyrazoles via Sequential (3 + 2)-Cycloaddition of Fluorinated Nitrile Imines with Chalcones and Solvent-Dependent Deacylative Oxidation Reactions

(2022) Anna Kowalczyk et al.   ORGANIC LETTERS

An overview of nitrile imine based [3+2] cycloadditions over half a decade

(2022) Ani Deepthi et al.   TETRAHEDRON

Regioselective Synthesis of 3‐Trifluoromethyl 4‐Subtituted Pyrazoles by [3+2] Cycloaddition of Trifluoroacetonitrile Imines and Nitroalkenes

(2022) Ke‐Hu Wang et al.   Asian Journal of Organic Chemistry

Base-Promoted (3 + 2) Cycloaddition of Trifluoroacetohydrazonoyl Chlorides with Imidates En Route to Trifluoromethyl-1,2,4-Triazoles

(2022) Yue Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Difluoromethyl Pyrazolines and Pyrazoles by [3+2] Cycloaddition Reaction of Difluoroacetohydrazonoyl Bromides with Electron‐deficient Olefins

(2022) Yuanyuan Ren et al.   Asian Journal of Organic Chemistry

Fluorinated Pyrazoles: From Synthesis to Applications

(2021) Pavel K. Mykhailiuk   CHEMICAL REVIEWS

Regioselective Decarboxylative Cycloaddition Route to Fully Substituted 3‐CF 3 ‐Pyrazoles from Nitrilimines and Isoxazolidinediones

(2021) Yu‐Chen Tian et al.   ADVANCED SYNTHESIS & CATALYSIS

Pyrazole Scaffold Synthesis, Functionalization, and Applications in Alzheimer’s Disease and Parkinson’s Disease Treatment (2011–2020)

(2021) Xuefei Li et al.   MOLECULES

Synthesis of 3H-1,2,4-Triazol-3-ones via NiCl2-Promoted Cascade Annulation of Hydrazonoyl Chlorides and Sodium Cyanate

(2021) Shiying Du et al.   ORGANIC LETTERS

Tricyclic Pyrazole-Based Compounds as Useful Scaffolds for Cannabinoid CB1/CB2 Receptor Interaction

(2021) Battistina Asproni et al.   MOLECULES

A straightforward conversion of 1,4-quinones into polycyclic pyrazoles via [3 + 2]-cycloaddition with fluorinated nitrile imines

(2021) Greta Utecht-Jarzyńska et al.   Beilstein Journal of Organic Chemistry

Green Synthesis of Bis(pyrazol‐5‐ole) and Pyrazolopyranopyrimidine Derivatives through Mechanochemistry Using Chitosan as a Biodegradable Catalyst

(2021) Bushra Chowhan et al.   ChemistrySelect

Synthesis of Difluoromethylated Pyrazoles by the [3 + 2] Cycloaddition Reaction of Difluoroacetohydrazonoyl Bromides

(2021) Tongyu Han et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Mechanocatalysis –  Using Milling Balls as Catalysts

(2020) Wilm Pickhardt et al.   CHEMISTRY-A EUROPEAN JOURNAL

Natural and Biomimetic Antitumor Pyrazoles, A Perspective

(2020) Nádia E. Santos et al.   MOLECULES

Pyrazoles as Key Scaffolds for the Development of Fluorine-18-Labeled Radiotracers for Positron Emission Tomography (PET)

(2020) Pedro M. O. Gomes et al.   MOLECULES

Mechanochemical and Mechanoenzymatic Synthesis of Pharmacologically Active Compounds: A Green Perspective

(2020) Mario Pérez-Venegas et al.   ACS Sustainable Chemistry & Engineering

A straightforward access to 3-trifluoromethyl-1H-indazoles via (3+2)-cycloaddition of arynes with nitrile imines derived from trifluoroacetonitrile

(2020) Anna Kowalczyk et al.   JOURNAL OF FLUORINE CHEMISTRY

Fluorinated hydrazonoyl chlorides as precursors for synthesis of antimicrobial azoles

(2020) Sami A. Al‐Hussain et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Styrylpyrazoles: Properties, Synthesis and Transformations

(2020) Pedro M. O. Gomes et al.   MOLECULES

Bromide-assisted chemoselective Heck reaction of 3-bromoindazoles under high-speed ball-milling conditions: synthesis of axitinib

(2018) Jingbo Yu et al.   Beilstein Journal of Organic Chemistry

Deacylative Reactions: Synthetic Applications

(2018) Aitor Ortega-Martínez et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ball Milling Promoted N-Heterocycles Synthesis

(2018) Taghreed El-Sayed et al.   MOLECULES

Polysubstituted 3-trifluoromethylpyrazoles: regioselective (3 + 2)-cycloaddition of trifluoroacetonitrile imines with enol ethers and functional group transformations

(2018) Greta Utecht et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Straightforward Access to Trifluoromethylated Spirobipyrazolines through a Double (3+2)-Cycloaddition of Fluorinated Nitrile Imines with Alkoxyallenes

(2018) Marcin Jasiński et al.   SYNLETT

Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?

(2018) Joseph L. Howard et al.   Chemical Science

Multicomponent mechanochemical synthesis

(2018) Marco Leonardi et al.   Chemical Science

First (3+2)-Cycloadditions of Thiochalcones as C=S Dipolarophiles: Efficient Synthesis of 1,3,4-Thiadiazoles via Reactions with Fluorinated Nitrile Imines

(2017) Grzegorz Mlostoń et al.   SYNTHESIS-STUTTGART

Trifluoromethylated 2,3-dihydro-1,3,4-thiadiazoles via the regioselective [3+2]-cycloadditions of fluorinated nitrile imines with aryl, hetaryl, and ferrocenyl thioketones

(2016) Grzegorz Mlostoń et al.   JOURNAL OF FLUORINE CHEMISTRY

Copper-catalyzed synthesis of 1,3,4-trisubstituted and 1,3,4,5-tetrasubstituted pyrazoles via [3+2] cycloadditions of hydrazones and nitroolefins

(2016) Chong Shi et al.   TETRAHEDRON

Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle

(2015) Demetrio Raffa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Green Mechanochemical Synthesis of New 3,5-Dimethyl-4-(arylsulfanyl)pyrazoles

(2015) Aamer Saeed et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Tautomeric equilibrium in trifluoroacetaldehyde arylhydrazones

(2015) Agata Wojciechowska et al.   TETRAHEDRON

Progress of the synthesis of condensed pyrazole derivatives (from 2010 to mid-2013)

(2014) Meng Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

How Mechanical and Chemical Features Affect the Green Synthesis of 1H-Pyrazoles in a Ball Mill

(2014) Guilherme C. Paveglio et al.   ACS Sustainable Chemistry & Engineering

Pyrazole containing natural products: Synthetic preview and biological significance

(2013) Vinod Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-Pot Synthesis of 3,5-Diphenyl-1H-pyrazoles from Chalcones and Hydrazine under Mechanochemical Ball Milling

(2013) Ze Zhang et al.   HETEROCYCLES

Preparation and Chemistry of 3/5-Halogenopyrazoles

(2012) Yves L. Janin   CHEMICAL REVIEWS

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS