Deacylative Reactions: Synthetic Applications

Palladium-catalyzed allylation and deacylative allylation of 3-acetyl-2-oxindoles with allylic alcohols

(2018) Aitor Ortega-Martínez et al.   TETRAHEDRON

Detrifluoroacetylative generation and chemistry of fluorine containing tertiary enolates

(2017) Lijun Zhang et al.   JOURNAL OF FLUORINE CHEMISTRY

Detrifluoroacetylative cascade reactions of bicyclic fluoro-enolates with ortho -phthalaldehyde: Aspects of reactivity, diastereo- and enantioselectivity

(2017) Wanxing Sha et al.   JOURNAL OF FLUORINE CHEMISTRY

Palladium(II)-Catalyzed Deacylative Allylic C–H Alkylation

(2017) Xiao-Le Zhou et al.   JOURNAL OF ORGANIC CHEMISTRY

Chemoselective SN2′ Allylations of Detrifluoroacetylatively In Situ Generated 3-Fluoroindolin-2-one-Derived Tertiary Enolates with Morita–Baylis–Hillman Carbonates

(2017) Yi Zhu et al.   JOURNAL OF ORGANIC CHEMISTRY

In Situ Electrophilic Activation of Hydrogen Peroxide for Catalytic Asymmetric α-Hydroxylation of 3-Substituted Oxindoles

(2017) Takashi Ooi et al.   SYNLETT

Synthesis of 3,3-Disubstituted 2-Oxindoles by Deacylative Alkylation of 3-Acetyl-2-oxindoles

(2017) José Sansano et al.   SYNTHESIS-STUTTGART

Asymmetric synthesis of C–F quaternary α-fluoro-β-amino-indolin-2-ones via Mannich addition reactions; facets of reactivity, structural generality and stereochemical outcome

(2017) Chen Xie et al.   RSC Advances

Synthesis of 2H-IndazolesviaTandem Palladium-Catalyzed Deacylative Cross-Coupling and Denitrogenative Cyclization of 2-Iodoazoarenes and 2-Iodoaryltriazenes with Acyldiazoacetates in One-Pot

(2016) Woo-Soon Yong et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic asymmetric detrifluoroacetylative aldol reactions of aliphatic aldehydes for construction of C-F quaternary stereogenic centers

(2016) Lijun Zhang et al.   JOURNAL OF FLUORINE CHEMISTRY

Catalytic cascade aldol–cyclization of tertiary ketone enolates for enantioselective synthesis of keto-esters with a C–F quaternary stereogenic center

(2016) Wanxing Sha et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Detrifluoroacetylative in Situ Generation of Free 3-Fluoroindolin-2-one-Derived Tertiary Enolates: Design, Synthesis, and Assessment of Reactivity toward Asymmetric Mannich Reactions

(2016) Chen Xie et al.   ORGANIC LETTERS

Assembly of Fluorinated Quaternary Stereogenic Centers through Catalytic Enantioselective Detrifluoroacetylative Aldol Reactions

(2015) Chen Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric synthesis of quaternary α-fluoro-β-keto-amines via detrifluoroacetylative Mannich reactions

(2015) Chen Xie et al.   CHEMICAL COMMUNICATIONS

Catalytic Enantioselective Decarboxylative Allylations of a Mixture of Allyl Carbonates and Allyl Esters: Total Synthesis of (−)- and (+)-Folicanthine

(2015) Santanu Ghosh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Progress in the in situ Detrifluoro­acetylative Generation of Fluoro Enolates and Their Reactions with Electrophiles

(2015) Haibo Mei et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of α,α-difluoro-β-amino carbonyl-containing sulfonamides and related compounds

(2015) Chen Xie et al.   JOURNAL OF FLUORINE CHEMISTRY

Oxidative Dimerization of 2-Oxindoles Promoted by KOtBu-I2: Total Synthesis of (±)-Folicanthine

(2015) Santanu Ghosh et al.   ORGANIC LETTERS

Synthesis of Aryldiazoacetates through Palladium(0)-Catalyzed Deacylative Cross-Coupling of Aryl Iodides with Acyldiazoacetates

(2014) Fei Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Retro-Claisen benzylation: direct use of benzyl alcohols in Pd-catalyzed couplings with nitriles

(2014) Tapan Maji et al.   CHEMICAL COMMUNICATIONS

Direct Allylic Functionalization Through Pd-Catalyzed C-H Activation

(2014) Frédéric Liron et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Generalized access to fluorinated β-keto amino compounds through asymmetric additions of α,α-difluoroenolates to CF3-sulfinylimine

(2014) Chen Xie et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic asymmetric synthesis of 3,3-disubstituted oxindoles: diazooxindole joins the field

(2014) Zhong-Yan Cao et al.   TETRAHEDRON LETTERS

Operationally convenient method for preparation of sulfonamides containing α,α-difluoro-β-amino carbonyl moiety

(2014) Chen Xie et al.   TETRAHEDRON LETTERS

Recent Advances in Catalytic Asymmetric Decarboxylative Addition Reactions

(2013) Zu-Li Wang   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Enantioselective Difluoroalkylation of Aldehydes

(2013) Peng Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Construction of 3-Hydroxy Oxindoles through a Decarboxylative Aldol Addition of Trifluoromethyl α-Fluorinatedgem-Diols toN-Benzyl Isatins

(2013) Ibrayim Saidalimu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of Asymmetric Deacylative Allylation

(2013) Alexander J. Grenning et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent development of direct asymmetric functionalization of inert C–H bonds

(2013) Chao Zheng et al.   RSC Advances

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones

(2012) Renato Dalpozzo et al.   CHEMICAL SOCIETY REVIEWS

Recent Advances in the Retro-Claisen Reaction and Its Synthetic Applications

(2012) Marko Jukic et al.   CURRENT ORGANIC SYNTHESIS

Benzylic Phosphates as Electrophiles in the Palladium-Catalyzed Asymmetric Benzylation of Azlactones

(2012) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions

(2011) Chao Liu et al.   CHEMICAL REVIEWS

Transition Metal-Catalyzed Decarboxylative Allylation and Benzylation Reactions

(2011) Jimmie D. Weaver et al.   CHEMICAL REVIEWS

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

Structure, Bioactivity and Synthesis of Natural Products with Hexahydropyrrolo[2,3-b]indole

(2011) Pau Ruiz-Sanchis et al.   CHEMISTRY-A EUROPEAN JOURNAL

Deacylative Allylation: Allylic Alkylation via Retro-Claisen Activation

(2011) Alexander J. Grenning et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cleavage of Carbon−Carbon Bonds through the Mild Release of Trifluoroacetate: Generation of α,α-Difluoroenolates for Aldol Reactions

(2011) Changho Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Catalytic, Asymmetric Formal Synthesis of (+)-Hamigeran B

(2011) Herschel Mukherjee et al.   ORGANIC LETTERS

Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action

(2011) Ke Shen et al.   Chemical Science

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Deacylative Allylation of Nitroalkanes: Unsymmetric Bisallylation by a Three-Component Coupling

(2010) Alexander J. Grenning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Asymmetric Benzylation of 3-Aryl Oxindoles

(2010) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concise Total Synthesis of (±)-Lycopladine A

(2010) John E. DeLorbe et al.   ORGANIC LETTERS

General synthesis of mono-, di-, and tri-acetylated indoles from indolin-2-ones

(2010) Mukund Jha et al.   TETRAHEDRON

Toward Efficient Palladium-Catalyzed Allylic CH Alkylation

(2009) Thomas Jensen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Transformations of Benzylic Carboxylates and Carbonates

(2009) Ryoichi Kuwano   SYNTHESIS-STUTTGART

Catalytic Enantioselective Approach to the Eudesmane Sesquiterpenoids: Total Synthesis of (+)-Carissone

(2008) Samantha R. Levine et al.   ORGANIC LETTERS