“Multiomics” Analyses Combined with Systems Pharmacology Reveal the Renoprotection of Mangiferin Monosodium Salt in Rats with Diabetic Nephropathy: Focus on Improvements in Renal Ferroptosis, Renal Inflammation, and Podocyte Insulin Resistance
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
“Multiomics” Analyses Combined with Systems Pharmacology Reveal the Renoprotection of Mangiferin Monosodium Salt in Rats with Diabetic Nephropathy: Focus on Improvements in Renal Ferroptosis, Renal Inflammation, and Podocyte Insulin Resistance
Authors
Keywords
-
Journal
Journal of Agricultural and Food Chemistry
Volume 71, Issue 1, Pages 358-381
Publisher
American Chemical Society (ACS)
Online
2022-12-15
DOI
10.1021/acs.jafc.2c05595
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Ferroptosis in cancer and cancer immunotherapy
- (2022) Lei Zhao et al. Cancer Communications
- Umbelliferone delays the progression of diabetic nephropathy by inhibiting ferroptosis through activation of the Nrf-2/HO-1 pathway
- (2022) Tong Jin et al. FOOD AND CHEMICAL TOXICOLOGY
- Ferroptosis as a Novel Therapeutic Target for Diabetes and Its Complications
- (2022) Xi-Ding Yang et al. Frontiers in Endocrinology
- Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
- (2022) Brent R. Stockwell CELL
- Effects of Metformin on Renal Function, Cardiac Function, and Inflammatory Response in Diabetic Nephropathy and Its Protective Mechanism
- (2022) Zhiping Zhang et al. DISEASE MARKERS
- SLC40A1 mediates ferroptosis and cognitive dysfunction in type 1 diabetes
- (2021) Lijun Hao et al. NEUROSCIENCE
- Ferritinophagy and ferroptosis in the management of metabolic diseases
- (2021) Amir Ajoolabady et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Insulin Signal Transduction Perturbations in Insulin Resistance
- (2021) Mariyam Khalid et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial regulation of ferroptosis
- (2021) Boyi Gan JOURNAL OF CELL BIOLOGY
- Cissus quadrangularis extract attenuates diabetic nephropathy by altering SIRT1/DNMT1 axis
- (2021) Anees Ahmed Syed et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- The aetiology and molecular landscape of insulin resistance
- (2021) David E. James et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Diabetic Nephropathy: Challenges in Pathogenesis, Diagnosis, and Treatment
- (2021) Nur Samsu Biomed Research International
- Ferroptosis in viral infection: the unexplored possibility
- (2021) Mao-peng Wang et al. ACTA PHARMACOLOGICA SINICA
- Therapeutic potential of pro-resolving mediators in diabetic kidney disease
- (2021) Tanwi Vartak et al. ADVANCED DRUG DELIVERY REVIEWS
- Insulin resistance in glomerular podocytes: Potential mechanisms of induction
- (2021) Dorota Rogacka ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Mangiferin: a review of dietary sources, absorption, metabolism, bioavailability, and safety
- (2021) Suhuan Mei et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- The management of diabetes mellitus by mangiferin: advances and prospects
- (2021) Mengdi Wang et al. Nanoscale
- Therapeutic potential of mangiferin against kidney disorders and its mechanism of action: A review
- (2021) Pei Teng Lum et al. SAUDI JOURNAL OF BIOLOGICAL SCIENCES
- Innate immunity in diabetic kidney disease
- (2020) Sydney C. W. Tang et al. Nature Reviews Nephrology
- Does adipose tissue inflammation drive the development of non-alcoholic fatty liver disease in obesity?
- (2020) Adryana Cordeiro et al. Clinics and Research in Hepatology and Gastroenterology
- Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
- (2020) Federica Zatterale et al. Frontiers in Physiology
- Inflammatory Targets in Diabetic Nephropathy
- (2020) Javier Donate-Correa et al. Journal of Clinical Medicine
- Ferroptosis in Cancer Cell Biology
- (2020) Christina M. Bebber et al. Cancers
- Chronic kidney disease in type 2 diabetes: Implications for managing glycaemic control, cardiovascular and renal risk
- (2020) Jeffrey W. Stephens et al. DIABETES OBESITY & METABOLISM
- Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy
- (2020) Sandra Rayego-Mateos et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Genetics of diabetes mellitus and diabetes complications
- (2020) Joanne B. Cole et al. Nature Reviews Nephrology
- Mechanisms of insulin resistance related to white, beige, and brown adipocytes
- (2020) Michael P. Czech Molecular Metabolism
- Phytochemicals as modulators of β-cells and immunity for the therapy of type 1 diabetes: Recent discoveries in pharmacological mechanisms and clinical potential
- (2020) Maria Karmella Apaya et al. PHARMACOLOGICAL RESEARCH
- Emerging Mechanisms and Disease Relevance of Ferroptosis
- (2020) Brent R. Stockwell et al. TRENDS IN CELL BIOLOGY
- Quercetin alleviates acute kidney injury by inhibiting ferroptosis
- (2020) Yue Wang et al. Journal of Advanced Research
- The Protective Effects of Cryptochlorogenic Acid on β-Cells Function in Diabetes in vivo and vitro via Inhibition of Ferroptosis
- (2020) Yi Zhou Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- De novo transcriptomic analysis predicts the effects of phenolic compounds in Ba River on the liver of female sharpbelly (Hemiculter lucidus)
- (2020) Jiahua Guo et al. ENVIRONMENTAL POLLUTION
- Proanthocyanidin promotes functional recovery of spinal cord injury via inhibiting ferroptosis
- (2020) Huangao Zhou et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Inflammation with the participation of arachidonic (AA) and linoleic acid (LA) derivatives (HETEs and HODEs) is necessary in the course of a normal reproductive cycle and pregnancy
- (2020) Justyna Kikut et al. JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- The Application of Ferroptosis in Diseases
- (2020) Yangmin Qiu et al. PHARMACOLOGICAL RESEARCH
- Quercetin Alleviates Ferroptosis of Pancreatic β Cells in Type 2 Diabetes
- (2020) Dan Li et al. Nutrients
- The Metabolic Underpinnings of Ferroptosis
- (2020) Jiashuo Zheng et al. Cell Metabolism
- Galangin attenuated cerebral ischemia-reperfusion injury by inhibition of ferroptosis through activating the SLC7A11/GPX4 axis in gerbils
- (2020) Xue Guan et al. LIFE SCIENCES
- Multi-Omics Analysis of Diabetic Nephropathy Reveals Potential New Mechanisms and Drug Targets
- (2020) Qian Sha et al. Frontiers in Genetics
- Mechanistic identification of biofluid metabolite changes as markers of acetaminophen-induced liver toxicity in rats
- (2019) Venkat R. Pannala et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Heracleum moellendorffii roots inhibit the production of pro-inflammatory mediators through the inhibition of NF-κB and MAPK signaling, and activation of ROS/Nrf2/HO-1 signaling in LPS-stimulated RAW264.7 cells
- (2019) Ha Na Kim et al. BMC Complementary and Alternative Medicine
- Pharmacokinetic Comparisons of Mangiferin and Mangiferin Monosodium Salt in Rat Plasma by UPLC-MS/MS
- (2019) Hongbin Guo et al. Journal of Chemistry
- Isolated mangiferin and naringenin exert antidiabetic effect via PPAR γ /GLUT4 dual agonistic action with strong metabolic regulation
- (2018) Ashok K. Singh et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Mangiferin prevents diabetic nephropathy progression and protects podocyte function via autophagy in diabetic rat glomeruli
- (2018) Xiaodan Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Regulatory Efficacy of Brown Seaweed Lessonia nigrescens Extract on the Gene Expression Profile and Intestinal Microflora in Type 2 Diabetic Mice
- (2018) Chao Zhao et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Unsolved mysteries: How does lipid peroxidation cause ferroptosis?
- (2018) Huizhong Feng et al. PLOS BIOLOGY
- Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
- (2018) Daniel J Fazakerley et al. eLife
- Glucose Transporters in Diabetic Kidney Disease—Friends or Foes?
- (2018) Anita A. Wasik et al. Frontiers in Endocrinology
- Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice
- (2018) Yingsong Jiang et al. MEDICAL SCIENCE MONITOR
- New pharmacological strategies for protecting kidney function in type 2 diabetes
- (2018) Marcel H A Muskiet et al. Lancet Diabetes & Endocrinology
- Effect of Cytochrome P450 Metabolites of Arachidonic Acid in Nephrology
- (2017) Fan Fan et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mangiferin: a natural miracle bioactive compound against lifestyle related disorders
- (2017) Muhammad Imran et al. Lipids in Health and Disease
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes
- (2017) Marcel H. A. Muskiet et al. Nature Reviews Nephrology
- Metabolomics in Prediabetes and Diabetes: A Systematic Review and Meta-analysis
- (2016) Marta Guasch-Ferré et al. DIABETES CARE
- Nephroprotective Effects of Metformin in Diabetic Nephropathy
- (2016) Sreenithya Ravindran et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
- (2016) Valerian E Kagan et al. Nature Chemical Biology
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- The role of 20-HETE in cardiovascular diseases and its risk factors
- (2016) Maayan Waldman et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Diabetic Nephropathy: Perspective on Novel Molecular Mechanisms
- (2016) Luigi Gnudi et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Compromised MAPK signaling in human diseases: an update
- (2015) Eun Kyung Kim et al. ARCHIVES OF TOXICOLOGY
- Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid
- (2015) William S. Powell et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Changing epidemiology of type 2 diabetes mellitus and associated chronic kidney disease
- (2015) Merlin C. Thomas et al. Nature Reviews Nephrology
- Modulation of Diabetes and Dyslipidemia in Diabetic Insulin-Resistant Rats by Mangiferin: Role of Adiponectin and TNF-α
- (2015) SAMIRA SALEH et al. ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
- Epidemiology and Risk Factors for Diabetic Kidney Disease
- (2014) Valma Harjutsalo et al. ADVANCES IN CHRONIC KIDNEY DISEASE
- Changes in Diabetes-Related Complications in the United States, 1990–2010
- (2014) Edward W. Gregg et al. NEW ENGLAND JOURNAL OF MEDICINE
- Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol
- (2013) Eva-Maria Küch et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Global Diabetes Survey—An annual report on quality of diabetes care
- (2013) Peter E.H. Schwarz et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding
- (2013) N. Turner et al. DIABETOLOGIA
- SUOX is a promising diagnostic and prognostic biomarker for hepatocellular carcinoma
- (2013) Guang-Zhi Jin et al. JOURNAL OF HEPATOLOGY
- NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy
- (2013) Pengchao Du et al. KIDNEY INTERNATIONAL
- Arachidonic acid and lipoxin A4 as possible endogenous anti-diabetic molecules
- (2013) Undurti N. Das PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Glutathione peroxidases
- (2012) Regina Brigelius-Flohé et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Cell Biology and Pathology of Podocytes
- (2011) Anna Greka et al. Annual Review of Physiology
- iTRAQ–2DLC–ESI–MS/MS Based Identification of a New Set of Immunohistochemical Biomarkers for Classification of Dysplastic Nodules and Small Hepatocellular Carcinoma
- (2011) Guang-Zhi Jin et al. JOURNAL OF PROTEOME RESEARCH
- Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy
- (2011) Juan F. Navarro-González et al. Nature Reviews Nephrology
- Effects of STZ-Induced Diabetes on the Relative Weights of Kidney, Liver and Pancreas in Albino Rats: A Comparative Study
- (2010) Muhammad Zafar et al. INTERNATIONAL JOURNAL OF MORPHOLOGY
- Thematic Review Series: Proteomics.An integrated omics analysis of eicosanoid biology,
- (2009) Matthew W. Buczynski et al. JOURNAL OF LIPID RESEARCH
- Determination of mangiferin in rat plasma by liquid–liquid extraction with UPLC–MS/MS
- (2009) Dandan Han et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- The x c − cystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine
- (2008) Jun Guan et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started