Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

The Problem of Establishing Relationships between Hepatic Steatosis and Hepatic Insulin Resistance

(2012) Robert V. Farese et al.   Cell Metabolism

Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet-Fed Mice

(2012) C. R. Bruce et al.   DIABETES

Lipid-Induced Endoplasmic Reticulum Stress in Liver Cells Results in Two Distinct Outcomes: Adaptation with Enhanced Insulin Signaling or Insulin Resistance

(2012) Caroline S. Achard et al.   ENDOCRINOLOGY

Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model*

(2012) Marcela Aparicio-Vergara et al.   HEPATOLOGY

Inactivation of MARK4, an AMP-activated Protein Kinase (AMPK)-related Kinase, Leads to Insulin Hypersensitivity and Resistance to Diet-induced Obesity

(2012) Chao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet-Induced Insulin Resistance

(2011) Y. S. Lee et al.   DIABETES

Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress

(2011) L. E. Wright et al.   DIABETOLOGIA

Effects of brief perturbations in energy balance on indices of glucose homeostasis in healthy lean men

(2011) M Lagerpusch et al.   INTERNATIONAL JOURNAL OF OBESITY

Influence of the Hepatic Eukaryotic Initiation Factor 2α (eIF2α) Endoplasmic Reticulum (ER) Stress Response Pathway on Insulin-mediated ER Stress and Hepatic and Peripheral Glucose Metabolism

(2011) Andreas L. Birkenfeld et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramide metabolism is affected by obesity and diabetes in human adipose tissue

(2011) A.U. Błachnio-Zabielska et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Re-evaluating lipotoxic triggers in skeletal muscle: Relating intramyocellular lipid metabolism to insulin sensitivity

(2011) Madeleen Bosma et al.   PROGRESS IN LIPID RESEARCH

Chronic consumption of a high-fat/high-fructose diet renders the liver incapable of net hepatic glucose uptake

(2010) Katie Colbert Coate et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Short-Term Overfeeding May Induce Peripheral Insulin Resistance Without Altering Subcutaneous Adipose Tissue Macrophages in Humans

(2010) C. S. Tam et al.   DIABETES

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

(2010) J. R. Ussher et al.   DIABETES

T-Cell Recruitment and Th1 Polarization in Adipose Tissue During Diet-Induced Obesity in C57BL/6 Mice

(2010) Katherine J. Strissel et al.   Obesity

Reactive oxygen species and insulin resistance: the good, the bad and the ugly

(2010) Tony Tiganis   TRENDS IN PHARMACOLOGICAL SCIENCES

Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent: Potent Tissue-Specific Effects of Medium-Chain Fatty Acids

(2009) N. Turner et al.   DIABETES

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men

(2009) Charlotte Brøns et al.   JOURNAL OF PHYSIOLOGY-LONDON

Insulin resistance is a cellular antioxidant defense mechanism

(2009) K. L. Hoehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Downregulation of Diacylglycerol Kinase Delta Contributes to Hyperglycemia-Induced Insulin Resistance

(2008) Alexander V. Chibalin et al.   CELL

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

Free fatty acids and skeletal muscle insulin resistance

(2008) Edward W Kraegen et al.   CURRENT OPINION IN LIPIDOLOGY

Adipose tissue fatty acid metabolism in insulin-resistant men

(2008) A. S. T. Bickerton et al.   DIABETOLOGIA

Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding

(2008) Vered Elgazar-Carmon et al.   JOURNAL OF LIPID RESEARCH