Advances in the Synthesis and Bio-Applications of Pyrazine Derivatives: A Review
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Advances in the Synthesis and Bio-Applications of Pyrazine Derivatives: A Review
Authors
Keywords
-
Journal
POLYCYCLIC AROMATIC COMPOUNDS
Volume -, Issue -, Pages 1-67
Publisher
Informa UK Limited
Online
2022-07-13
DOI
10.1080/10406638.2022.2092873
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Additive-Assisted Optimization in Morphology and Optoelectronic Properties of Inorganic Mixed Sn-Pb Halide Perovskites
- (2022) Rubaiya Murshed et al. Materials
- Review on Synthesis, Reactions and Biological Properties of Seven Member Heterocyclic Compounds: Azepine, Azepane, Azepinone
- (2021) Manvinder Kaur et al. CURRENT ORGANIC CHEMISTRY
- Synthetic Studies toward DNA-Encoded Heterocycles Based on the On-DNA Formation of α,β-Unsaturated Ketones
- (2021) Sixiu Liu et al. ORGANIC LETTERS
- DFT study of low-energy electron interaction with pyridine, pyrazine and their halo derivatives
- (2021) Natalia Tańska EUROPEAN PHYSICAL JOURNAL D
- Subcritical water extraction as a circular economy approach to recover energy and agrochemicals from sewage sludge
- (2021) Matat Zohar et al. JOURNAL OF ENVIRONMENTAL MANAGEMENT
- Synthesis and Characterization of a Novel Heterocyclic Schiff Base and Development of a Fluorescent Sensor for Vitamin B12
- (2021) Savitha Devaswamparambil Pradeep et al. JOURNAL OF FLUORESCENCE
- Structure–Activity Relationship Studies on Oxazolo[3,4-a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent In Vivo Activity
- (2021) Valentina Albanese et al. JOURNAL OF MEDICINAL CHEMISTRY
- 2,2′-(Arylmethylene)bis(3-hydroxy-5,5-dimethylcyclohex-2-enone) crystals formation via atom economy reaction and their antioxidant activity
- (2021) Deepa Thakur et al. MONATSHEFTE FUR CHEMIE
- Current status of quinoxaline and quinoxaline 1,4‐di‐ N ‐oxides derivatives as potential antiparasitic agents
- (2021) Jacqueline Soto‐Sánchez et al. Chemical Biology & Drug Design
- Potential application of lactic acid bacteria in the biopreservation of red grape from mycotoxigenic fungi
- (2021) Victor Dopazo et al. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
- Photosynthesis-Inhibiting Activity of N-(Disubstituted-phenyl)-3-hydroxynaphthalene-2-carboxamides
- (2021) Jiri Kos et al. MOLECULES
- Heterocyclic Aromatic Amines in Meat: Formation, Isolation, Risk Assessment, and Inhibitory Effect of Plant Extracts
- (2021) Hafiz Rehan Nadeem et al. Foods
- B ← N Coordination Enables Efficient p-Doping in a Pyrazine-Based Polymer Donor Toward Enhanced Photovoltaic Performance
- (2021) Liang Guo et al. MACROMOLECULES
- Synthesis of 2-arylideneimidazo[1,2-a]pyrazine-3,6,8(2H,5H,7H)-triones as a result of oxidation of 4-arylidene-2-methyl-1H-imidazol-5(4H)-ones with selenium dioxide
- (2020) Elvira R. Zaitseva et al. Chemistry of Heterocyclic Compounds
- Synthesis of Novel 1-(1,5-Diaryl-1,10b-Dihydropyrrolo- [1,2-A][1,2,4]Triazolo[3,4-C]Pyrazin-3-Yl)Ethanones Via 1,3-Dipolar Cycloaddition of Nitrilimine
- (2020) Yulin Huang et al. Chemistry of Heterocyclic Compounds
- An efficient synthesis of spiroacridinone derivatives from the facile reaction of isatins, dimedone, and 5‐aminoindazole (6‐aminoindazole or 5‐aminoindole)
- (2020) Wen‐Ting Zhang et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Molecular Interactions of Pyrazine-Based Compounds to Proteins
- (2020) Martin Juhás et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of Substituted 6,7-Dihydro-5H-pyrrolo[2,3-c]pyridazines/pyrazines via Catalyst-Free Tandem Hydroamination–Aromatic Substitution
- (2020) Jeremy A. Turkett et al. JOURNAL OF ORGANIC CHEMISTRY
- A panchromatic pyrazine-fused porphyrin dimer
- (2020) Inna A. Abdulaeva et al. MENDELEEV COMMUNICATIONS
- A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications
- (2020) Nagaraju Kerru et al. MOLECULES
- From Acylethynylpyrroles to Pyrrolo[1,2-a]pyrazines in One Step
- (2020) E. F. Sagitova et al. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
- Metal‐Free Oxidative [5+1] Cyclization of 1,5‐Enynes for the Synthesis of Pyrazine 1‐Oxide
- (2020) Xiao‐Feng Xia et al. ADVANCED SYNTHESIS & CATALYSIS
- Pyrazines: Synthesis and Industrial Application of these Valuable Flavor and Fragrance Compounds
- (2020) Frederik B. Mortzfeld et al. Biotechnology Journal
- Design, Synthesis and Opto-electrochemical Properties of Novel Donor–Acceptor Based 2,3-Di(hetero-2-yl)pyrido[2,3-b]pyrazine Amine Derivatives as Blue-Orange Fluorescent Materials
- (2020) Suraj S. Mahadik et al. DYES AND PIGMENTS
- Green synthesis and investigation of antioxidant ability new pyrazines containing pyrrolo[2,1‐a]isoquinolines derivatives
- (2020) Seyyed Ali Moghaddas et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Biobased Pyrazine-Containing Polyesters
- (2020) Martien A. Würdemann et al. ACS Sustainable Chemistry & Engineering
- Pyrazine-EDOT D-A-D type Hybrid Polymer for Patterned Flexible Electrochromic Devices
- (2020) Faqi Hu et al. ELECTROCHIMICA ACTA
- A convenient synthesis, reactions and biological evaluation of novel pyrazolo[3,4-b]selenolo[3,2-e]pyrazine heterocycles as potential anticancer and antimicrobial agents
- (2020) Remon M. Zaki et al. MEDICINAL CHEMISTRY RESEARCH
- Current Contributions of Organofluorine Compounds to the Agrochemical Industry
- (2020) Yuta Ogawa et al. iScience
- Spectroscopic studies, density functional theory calculations, non-linear optical properties, biological activity of 1-hydroxy-4-((4-(N-(pyrimidin-2-yl)sulfamoyl)phenyl)diazenyl)-2-naphthoic acid and its chelates with Nickel (II), Copper (II), Zinc (II) and Palladium (II) metal ions
- (2020) Nora S. Abdel-Kader et al. JOURNAL OF MOLECULAR STRUCTURE
- Synthesis, photophysical and nonlinear optical properties of [1,2,5]oxadiazolo[3,4-b]pyrazine-based linear push-pull systems
- (2020) Egor V. Verbitskiy et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
- Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents
- (2020) Afzal B. Shaik et al. Arabian Journal of Chemistry
- Carboxylate substituted pyrazine: A simple and low-cost building block for novel wide bandgap polymer donor enables 15.3% efficiency in organic solar cells
- (2020) Jingnan Wu et al. Nano Energy
- Discovery of a Potent Tyrosine Kinase AXL Inhibitor Bearing the 3-((2,3,4,5-Tetrahydro-1H-benzo[d]azepin-7-yl)amino)pyrazine Core
- (2019) Yueliang Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis, crystal structure, insecticidal activities, molecular docking and QSAR studies of some new phospho guanidines and phospho pyrazines as cholinesterase inhibitors
- (2019) Khodayar Gholivand et al. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
- Highly regio- and diastereoselective synthesis of oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indoles, based on a post-Ugi condensation: joint experimental and computational study
- (2019) Morteza Shiri et al. Journal of the Iranian Chemical Society
- A Facile Synthesis of Substituted 2‐(5‐(Benzylthio)‐1,3,4‐oxadiazol‐2‐yl)pyrazine Using Microwave Irradiation and Conventional Method with Antioxidant and Anticancer Activities
- (2019) Sanjeev R. Patil et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Design, Synthesis, and Biological Evaluation of Novel Pyrrolo[1,2-a]pyrazine Derivatives
- (2019) Jinwoo Kim et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Functional π-Conjugated Two-Dimensional Covalent Organic Frameworks
- (2019) H. Vignesh Babu et al. ACS Applied Materials & Interfaces
- Design, synthesis and biological evaluation of imidazo[1,5-a]pyrazin-8(7H)-one derivatives as BRD9 inhibitors
- (2019) Peiyuan Zheng et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis of 7-arylimidazo[1,2-a]pyrazin-8(7H)-one derivatives
- (2019) Svitlana S. Kovalenko et al. Chemistry of Heterocyclic Compounds
- In Search of Bioactivity – Phyllobilins, an Unexplored Class of Abundant Heterocyclic Plant Metabolites from Breakdown of Chlorophyll
- (2019) Simone Moser et al. ISRAEL JOURNAL OF CHEMISTRY
- Synthesis and characterization of new asymmetric thieno[3,4-b]pyrazine-based D−π−A−A type small molecular donors with near-infrared absorption and their photovoltaic applications
- (2019) Shu-Hua Chou et al. ORGANIC ELECTRONICS
- Tandem Pd-Catalyzed Intermolecular Allylic Alkylation/Allylic Dearomatization Reaction of Benzoylmethyl pyridines, Pyrazines, and Quinolines
- (2019) Hui-Jun Zhang et al. ORGANIC LETTERS
- Pyrazine-2-carbohydrazone of Pyridoxal 5′-Phosphate: Synthesis, Stability, Formation Kinetics, and Interaction with DNA
- (2019) G. A. Gamov et al. RUSSIAN JOURNAL OF GENERAL CHEMISTRY
- Synthesis, properties and application of novel 5,6,5,6-tetracyclic pyrazine/pyrrole-fused unsymmetric bis(BF2) fluorescent dyes: BOPYPYs
- (2019) Xindong Jiang et al. CHINESE CHEMICAL LETTERS
- Metal–organic frameworks with multicomponents in order
- (2019) Qingqing Pang et al. COORDINATION CHEMISTRY REVIEWS
- Substantiation to structure-property of pyrazine-based compounds by undeniable impress of its different connectivities
- (2019) Maryam Bazargan et al. JOURNAL OF MOLECULAR STRUCTURE
- Micellar Brønsted Acid Mediated Synthesis of DNA-Tagged Heterocycles
- (2019) M. Klika Škopić et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Use of Pyrimidine and Pyrazine Bridges as a Design Strategy To Improve the Performance of Thermally Activated Delayed Fluorescence Organic Light Emitting Diodes
- (2019) Paloma Lays dos Santos et al. ACS Applied Materials & Interfaces
- A Pyrazine-Based Polymer for Fast-Charge Batteries
- (2019) Minglei Mao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of pyrazolo[1,5-a]pyrazin-4-ylacetonitriles and their annulation with pyridine ring
- (2019) Nazar M. Tsizorik et al. Chemistry of Heterocyclic Compounds
- Synthesis of 4-aryl(hetaryl)pyrazolo[1,5-a]pyrazines by palladium-catalyzed Suzuki–Miyaura cross coupling
- (2019) Yevhenii V. Hrynyshyn et al. Chemistry of Heterocyclic Compounds
- Synthesis and properties of liquid pyrazine dyes
- (2019) Jae-Young Lee et al. DYES AND PIGMENTS
- Effective synthesis of benzimidazoles-imidazo[1,2-a]pyrazine conjugates: A comparative study of mono-and bis-benzimidazoles for antitumor activity
- (2019) Iqubal Singh et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The bioisosteric modification of pyrazinamide derivatives led to potent antitubercular agents: Synthesis via click approach and molecular docking of pyrazine-1,2,3-triazoles
- (2019) Rajkumar Reddyrajula et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Expansion of chemical space based on a pyrrolo[1,2-a]pyrazine core: Synthesis and its anticancer activity in prostate cancer and breast cancer cells
- (2019) Yohan Seo et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and characterization of vinazene end capped dipyrrolo[2,3-b:2′,3′-e]pyrazine-2,6(1H,5H)-dione small molecules as non-fullerene acceptors for bulk heterojunction organic solar cells
- (2019) Gangala Sivakumar et al. MATERIALS CHEMISTRY AND PHYSICS
- Controllable luminescent behaviors with pyrazine and benzimidazole groups: Syntheses, crystal structures and properties
- (2019) Yong-Tao Wang et al. OPTICAL MATERIALS
- Discovery of 2,6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinases
- (2018) Lakshmaiah Gingipalli et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis, biological evaluation, and metabolic stability of phenazine derivatives as antibacterial agents
- (2018) Maddeboina Krishnaiah et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- A Concise Review on the Synthesis and Reactions of Pyrazolopyrazine Heterocycles
- (2018) Mokhtar A. Abd ul-Malik et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Synthesis of a polymer-capped palladium nanoparticles and its application as a reusable catalyst in oxidative coupling reaction of α-hydroxyketones and 1,2-diamines for preparation of pyrazines and quinoxalines
- (2018) Mohammad Ali Karimi Zarchi et al. Journal of the Iranian Chemical Society
- Formation of spirocyclic indenopyrazine–pyridooxazines via 1,4-dipolar cycloaddition reaction
- (2018) Hosna Sayadian et al. MONATSHEFTE FUR CHEMIE
- Design, Synthesis and Evaluation of Antitubercular Activity of Novel 1,2,4-Triazoles Against MDR Strain of Mycobacterium tuberculosis
- (2018) T. N. V. Ganesh Kumar et al. PHARMACEUTICAL CHEMISTRY JOURNAL
- Synthesis of Angular [1,2,5]Oxadiazolo[3,4-b]pyrazino-[1′,2′ : 1,2]pyrrolo[2,3-e][1,4]diazepine by Stepwise Reaction of Pyrrolo[1,2-a]pyrazinetrione with 3,4-Diaminofurazan
- (2018) A. V. Chervyakov et al. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
- Synthesis and Structure of a New Semisynthetic Taraxerone Derivative Fused to a Pyrazine Ring through the C2–C3 Bond
- (2018) A. D. Zorina et al. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
- Synthesis of 8a-Chlorotetrahydropyrrolo[1,2-H]pyrazine-1,6,7-(2H)-triones from 3-Methylidenepiperazin-2-ones and Oxalyl Chloride
- (2018) А. V. Chervyakov et al. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
- Synthesis of novel 1,2-dihydropyrrolo[1,2- a ]pyrazin-1(2 H )-one derivatives
- (2018) Iryna O. Yaremchuk et al. TETRAHEDRON LETTERS
- Efficient Access to Imidazo[1,2-a]pyridines/pyrazines/pyrimidines via Catalyst-Free Annulation Reaction under Microwave Irradiation in Green Solvent
- (2018) R. Nishanth Rao et al. ACS Combinatorial Science
- Sustainable Routes for the Synthesis of Renewable Heteroatom-Containing Chemicals
- (2018) Max J. Hülsey et al. ACS Sustainable Chemistry & Engineering
- Synthesis of 2-Acyl-Substituted Pyrazine Derivatives through Silver-Catalyzed Decarboxylative Coupling Reactions
- (2018) Yuan Li et al. ChemistrySelect
- Synthesis, annulation, and heterofunctionalization of 4-hydrazinylpyrazolo[1,5-а]pyrazines
- (2018) Nazar M. Tsizorik et al. Chemistry of Heterocyclic Compounds
- Investigation of Photophysical Properties on Carbazole and Pyrazine Based Conjugated Polymer: Excellent Fluorescence Sensing Towards to Cadmium Ion
- (2018) Anjali Upadhyay et al. POLYMER SCIENCE SERIES A
- 9-Ethyl-3-{6-(het)aryl-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-yl}-9H-carbazoles: synthesis and study of sensitivity to nitroaromatic compounds
- (2018) E. V. Verbitskiy et al. RUSSIAN CHEMICAL BULLETIN
- Synthesis of Spiro[indole-3,2′-pyrroles] from Pyrrolopyrazinetriones and Aminocyclohexenones
- (2018) A. V. Chervyakov et al. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
- Phthalocyanine-based photosensitizer with tumor-pH-responsive properties for cancer theranostics
- (2018) Shufeng Yan et al. Journal of Materials Chemistry B
- Heteropore covalent organic frameworks: a new class of porous organic polymers with well-ordered hierarchical porosities
- (2018) Rong-Ran Liang et al. Organic Chemistry Frontiers
- Tracking the Process of a Solvothermal Domino Reaction Leading to a Stable Triheteroarylmethyl Radical: A Combined Crystallographic and Mass-Spectrometric Study
- (2018) Bin Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Palladium Nanoparticles Encapsulated in the MIL-101-Catalyzed One-Pot Reaction of Alcohol Oxidation and Aldimine Condensation
- (2018) Yu-Yang Zhang et al. INORGANIC CHEMISTRY
- Pyrazine derivatives as green oil field corrosion inhibitors for steel
- (2018) I.B. Obot et al. JOURNAL OF MOLECULAR LIQUIDS
- Therapeutic potential of pteridine derivatives: A comprehensive review
- (2018) Violeta Carmona-Martínez et al. MEDICINAL RESEARCH REVIEWS
- Synthesis of 3-Benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
- (2018) V. A. Gaidukevich et al. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
- Selective synthesis of oxazoles and pyrazines from α-bromo-1-phenylethanone using a by-product-promoted strategy
- (2018) Changhui Liu et al. TETRAHEDRON
- Self-assembled nematic colloidal motors powered by light
- (2018) Ye Yuan et al. Nature Communications
- Synthesis of 1,4-dihydropyridine and polyhydroquinoline derivatives via Hantzsch reaction using nicotinic acid as a green and reusable catalyst
- (2018) Jamal Davarpanah et al. JOURNAL OF MOLECULAR STRUCTURE
- Synthesis, characterization and optoelectronic properties of pyrrolopyrazine based Y-shaped color-tunable dipolar molecules
- (2018) Puttavva Meti et al. DYES AND PIGMENTS
- Design and synthesis of novel 7-aminosubstituted pyrido[2,3- b ]pyrazines exhibiting anti-breast cancer activity
- (2017) Orestis Argyros et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- New 1,3,4-thiadiazole compounds including pyrazine moiety: Synthesis, structural properties and antimicrobial features
- (2017) Mahmut Gür et al. JOURNAL OF MOLECULAR STRUCTURE
- Phosphine Supported Ruthenium Nanoparticle Catalyzed Synthesis of Substituted Pyrazines and Imidazoles from α-Diketones
- (2017) Prasad Ganji et al. JOURNAL OF ORGANIC CHEMISTRY
- A Flexible Strategy for the Regiocontrolled Synthesis of Pyrazolo[1,5-a]pyrazines
- (2017) Peter J. Lindsay-Scott et al. JOURNAL OF ORGANIC CHEMISTRY
- Application of novel nanostructured dinitropyrazine molten salt catalyst for the synthesis of sulfanylpyridines via anomeric based oxidation
- (2017) Mohammad Ali Zolfigol et al. Journal of the Iranian Chemical Society
- One-pot synthesis of novel 1-(1H-tetrazol-5-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine derivatives via an Ugi-azide 4CR process
- (2017) Mehdi Ghandi et al. MOLECULAR DIVERSITY
- Synthesis of fluoroquinoxalin-2(1H)-one derivatives containing substituents in the pyrazine and benzene fragments
- (2017) Yu. A. Azev et al. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
- Side-chain fluorination on the pyrido[3,4-b]pyrazine unit towards efficient photovoltaic polymers
- (2017) Tao Wang et al. Science China-Chemistry
- Efficient synthesis of pyrazine boronic esters via palladium-catalyzed Miyaura borylation
- (2017) Hongtao Lu et al. TETRAHEDRON LETTERS
- The first stable examples of compounds containing both diazonium and acyl azide, and synthesis of a new pyrazino[2′,3′:3,4]pyrazolo[5,1- c ][1,2,4]triazin-4(6 H )-one heterocyclic system
- (2017) Sergey M. Ivanov et al. TETRAHEDRON LETTERS
- Design and synthesis of 5-methylpyrazine-2-carbohydrazide derivatives: A new anti-tubercular scaffold
- (2017) P.B. Miniyar et al. Arabian Journal of Chemistry
- Recent advances in post-synthetic modification of metal–organic frameworks: New types and tandem reactions
- (2017) Zheng Yin et al. COORDINATION CHEMISTRY REVIEWS
- Molecular design, synthesis and anticoagulant activity evaluation of fluorinated dabigatran analogues
- (2016) Fei Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Total synthesis and cytotoxic activities of longamide B, longamide B methyl ester, hanishin, and their analogues
- (2016) Deng-Gao Zhao et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and docking studies of pyrazine–thiazolidinone hybrid scaffold targeting dormant tuberculosis
- (2016) T.S. Chitre et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Methemoglobin Formation and Characterization of Hemoglobin Adducts of Carcinogenic Aromatic Amines and Heterocyclic Aromatic Amines
- (2016) Khyatiben V. Pathak et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Synthesis and Medicinal Applications of Benzimidazoles: An Overview
- (2016) Sreerama Rajasekhar et al. CURRENT ORGANIC SYNTHESIS
- Studying the interaction between three synthesized heterocyclic sulfonamide compounds with hemoglobin by spectroscopy and molecular modeling techniques
- (2016) Samane Naeeminejad et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Synthesis of pyrazine via chemoselective reduction of β-keto-α-oximino ester using baker’s yeast
- (2016) Kilwoong Mo et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- Synthesis of Perylene Imide Diones as Platforms for the Development of Pyrazine Based Organic Semiconductors
- (2016) Paula de Echegaray et al. JOURNAL OF ORGANIC CHEMISTRY
- Switchable Synthesis of Pyrroles and Pyrazines via Rh(II)-Catalyzed Reaction of 1,2,3-Triazoles with Isoxazoles: Experimental and DFT Evidence for the 1,4-Diazahexatriene Intermediate
- (2016) Nikolai V. Rostovskii et al. JOURNAL OF ORGANIC CHEMISTRY
- Ionic liquid functionalized cellulose as an efficient heterogeneous catalyst for the facile and green synthesis of benzoxazine, pyrazine and quinoxaline derivatives in aqueous media
- (2016) Sevil Vaghefi Moghaddam et al. Journal of the Iranian Chemical Society
- Design, synthesis, and cytostatic activity of novel pyrazine sorafenib analogs
- (2016) Zrinka Rajić Džolić et al. MEDICINAL CHEMISTRY RESEARCH
- Highly efficient synthesis of quinoxaline derivatives from 1,2-benzenediamine and $$\alpha $$ α -aminoxylated 1,3-dicarbonyl compounds
- (2016) Jianwei Yan et al. MOLECULAR DIVERSITY
- Tetramethylpyrazine Ameliorates Rotenone-Induced Parkinson’s Disease in Rats: Involvement of Its Anti-Inflammatory and Anti-Apoptotic Actions
- (2016) Haidy E. Michel et al. MOLECULAR NEUROBIOLOGY
- Synthesis of polyfunctionalized pyrido[1,2-a]pyrazines and pyrazino[1,2-a]quinolines via one-pot multicomponent reactions
- (2016) Renata I. Eften’eva et al. MONATSHEFTE FUR CHEMIE
- Small heterocycles as highly luminescent building blocks in the solid state for organic synthesis
- (2016) Fabiano da Silveira Santos et al. NEW JOURNAL OF CHEMISTRY
- Molecular diversity in cyclization of Ugi-products leading to the synthesis of 2,5-diketopiperazines: computational study
- (2016) Vahideh Zadsirjan et al. RESEARCH ON CHEMICAL INTERMEDIATES
- Synthesis and conformational study of novel pyrazine-based pseudopeptides bearing amidoxime, amidoxime ester and 1,2,4-oxadiazole units
- (2016) Olga V. Ovdiichuk et al. TETRAHEDRON
- Facile synthesis of hexahydropyrazino[2,3-e]pyrazines from 3-aminomethyl-1,2,4-triazoles
- (2016) Dmytro M. Khomenko et al. TETRAHEDRON LETTERS
- Natural Therapies for Cardiovascular Diseases
- (2016) Xiaochen Yang et al. Biomed Research International
- Covalent organic frameworks: a materials platform for structural and functional designs
- (2016) Ning Huang et al. Nature Reviews Materials
- Synthesis and antimycobacterial evaluation of 5-alkylamino-N-phenylpyrazine-2-carboxamides
- (2015) Jan Zitko et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design, synthesis and anxiolytic-like activity of 1-arylpyrrolo[1,2- a ]pyrazine-3-carboxamides
- (2015) G.V. Mokrov et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis, antimycobacterial and antifungal evaluation of some new 1-ethyl-5-(hetero)aryl-6-styryl-1,6-dihydropyrazine-2,3-dicarbonitriles
- (2015) Egor V. Verbitskiy et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Pyrazine- and pyridine-substituted prop-2-yn-1-ols, but-3-yn-2-ols, and but-3-yn-2-ones – purification, stability, and handling revised
- (2015) Claudia Schindler et al. Chemistry of Heterocyclic Compounds
- Synthetic Routes to Coelenterazine and Other Imidazo[1,2-a]pyrazin-3-one Luciferins: Essential Tools for Bioluminescence-Based Investigations
- (2015) Eloi P. Coutant et al. CHEMISTRY-A EUROPEAN JOURNAL
- A Review of Pharmacokinetic Drug–Drug Interactions with the Anthelmintic Medications Albendazole and Mebendazole
- (2015) Shane Ashley Pawluk et al. CLINICAL PHARMACOKINETICS
- Structure-Based Discovery of PDEs Inhibitors
- (2015) Li Li et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines
- (2015) Pascal Marchand et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- [1,2,5]Selenadiazolo[3,4-b]pyrazines: Synthesis from 3,4-Diamino-1,2,5-selenadiazole and Generation of Persistent Radical Anions
- (2015) Lidia S. Konstantinova et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Design of Pyrazolo-pyrrolo-pyrazines and Pyrazolo-pyrrolo-diazepines via AuCl3-Catalyzed and NaH-Supported Cyclization of N-Propargyl Pyrazoles
- (2015) Sinan Basceken et al. JOURNAL OF ORGANIC CHEMISTRY
- Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions
- (2015) Monika Gaba et al. MEDICINAL CHEMISTRY RESEARCH
- Biologically Active Benzimidazole Derivatives
- (2015) Subramaniyan Arulmurugan et al. MINI-REVIEWS IN ORGANIC CHEMISTRY
- Synthesis of Unsymmetrical Pyrazines Based on α-Diazo Oxime Ethers
- (2015) Nicole S. Y. Loy et al. ORGANIC LETTERS
- Endophytes-assisted biocontrol: novel insights in ecology and the mode of action of Paenibacillus
- (2015) Daria Rybakova et al. PLANT AND SOIL
- Synthesis of quinoxalines and pyrido[2,3-b]pyrazines by Suzuki–Miyaura cross-coupling reaction
- (2015) Arjun Kumbhar et al. RESEARCH ON CHEMICAL INTERMEDIATES
- Synthesis of 8-aroylpyrrolo[1,2-a]pyrazine-1,6,7(2H)-triones and their reaction with water. New analogs of cyclic dipeptides
- (2015) A. V. Chervyakov et al. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
- Efficient Synthesis of (–)-Hanishin, (–)-Longamide B, and (–)-Longamide B Methyl Ester through Piperazinone Formation from 1,2-Cyclic Sulfamidates
- (2015) Koichi Fukase et al. SYNLETT
- Synthesis of tetraaryl- and tetraalkenylpyrazines by Suzuki–Miyaura reactions of tetrachloropyrazine
- (2015) Andranik Petrosyan et al. TETRAHEDRON
- Nature loves nitrogen heterocycles
- (2015) Christopher T. Walsh TETRAHEDRON LETTERS
- Facile one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazines via oxidative cyclisation using chloramine T
- (2015) Sanjib Mal et al. TETRAHEDRON LETTERS
- Nanosize Gold Promoted Vanadium Oxide Catalysts for Ammoxidation of 2-Methylpyrazine to 2-Cyanopyrazine
- (2015) A. Alshammari et al. TOPICS IN CATALYSIS
- Nano Brönsted solid acid containing double-charged diazoniabi-cyclo[2.2.2]octane chloride supported on nano rice husk silica: an efficient catalyst for the one-pot synthesis of phthalazine compounds
- (2015) Jamal Davarpanah et al. RSC Advances
- Synthesis and Evaluation of F-18 Labeled Pyrido[3,2-B]pyrazine Derivative as a Potential Imaging Agent for Non-Small-Cell Lung Cancer
- (2015) Jeong Hoon Park et al. BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Unequivocal Role of Pyrazine Ring in Medicinally Important Compounds: A Review
- (2015) Pankaj Miniyar et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Comprehensive Review in Current Developments of Benzimidazole-Based Medicinal Chemistry
- (2014) Rangappa S. Keri et al. Chemical Biology & Drug Design
- Diastaphenazine, a new dimeric phenazine from an endophytic Streptomyces diastaticus subsp. ardesiacus
- (2014) Yiqing Li et al. JOURNAL OF ANTIBIOTICS
- Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
- (2014) Edon Vitaku et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of Saturated N-Heterocycles
- (2014) Cam-Van T. Vo et al. JOURNAL OF ORGANIC CHEMISTRY
- Highly selective base-catalyzed ring closing Ugi-adducts from the reaction of 2-formylindole, 2-bromoacetic acid, amines and isocyanides
- (2014) Morteza Shiri et al. Journal of the Iranian Chemical Society
- Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases
- (2013) Francesco Casuscelli et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Polymorphism of Dehydro-Aripiprazole, the Active Metabolite of the Antipsychotic Drug Aripiprazole (Abilify)
- (2013) Tarek A. Zeidan et al. CRYSTAL GROWTH & DESIGN
- A simple synthesis of salicylamide and 2,5-diphenylpyrazine
- (2013) Luo Mei et al. RESEARCH ON CHEMICAL INTERMEDIATES
- Palau’amine and Related Oroidin Alkaloids Dibromophakellin and Dibromophakellstatin Inhibit the Human 20S Proteasome
- (2012) Theresa A. Lansdell et al. JOURNAL OF NATURAL PRODUCTS
- Phase Behavior and Conductivity of Sulfonated Block Copolymers Containing Heterocyclic Diazole-Based Ionic Liquids
- (2012) Onnuri Kim et al. MACROMOLECULES
- Evaluation of Antioxidant and Immunity Function of Tetramethylpyrazine Phosphate Tablets in Vivo
- (2012) Ling Guo et al. MOLECULES
- An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals
- (2011) Marcus Baumann et al. Beilstein Journal of Organic Chemistry
- Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: An orally active anti-cancer drug waiting for its call-of-duty?
- (2011) Hayden Matthews et al. INTERNATIONAL JOURNAL OF CANCER
- 3-TrifluoromethylquinoxalineN,N′-Dioxides as Anti-Trypanosomatid Agents. Identification of Optimal Anti-T. cruziAgents and Mechanism of Action Studies
- (2011) Diego Benitez et al. JOURNAL OF MEDICINAL CHEMISTRY
- A novel sulfonic acid functionalized ionic liquid catalyzed multicomponent synthesis of 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione derivatives in water
- (2011) Zhiwei Chen et al. TETRAHEDRON LETTERS
- Pyrazine Biosynthesis in Corynebacterium glutamicum
- (2010) Jeroen S. Dickschat et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Alkylpyrazines: alarm pheromone components of the little fire ant, Wasmannia auropunctata (Roger) (Hymenoptera, Formicidae)
- (2010) D. N. Showalter et al. INSECTES SOCIAUX
- Heterocycles in organic synthesis: thiazoles and triazoles as exemplar cases of synthetic auxiliaries
- (2010) Alessandro Dondoni ORGANIC & BIOMOLECULAR CHEMISTRY
- The Evaluation of Some Heterocycles as Antioxidant Additives for Lubricating Oils
- (2010) O. M. O. Habib et al. PETROLEUM SCIENCE AND TECHNOLOGY
- From anti-fouling to biofilm inhibition: New cytotoxic secondary metabolites from two Indonesian Agelas sponges
- (2009) Triana Hertiani et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Alternating Copolymerizations Using a Grubbs-Type Initiator with an Unsymmetrical, Chiral N-Heterocyclic Carbene Ligand
- (2008) Kati Vehlow et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- One-pot, three-component route to 2H-indazolo[2,1-b]phthalazine-triones
- (2008) Maryam Sayyafi et al. TETRAHEDRON
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started