Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents

Synthesis, Biological and Computational Evaluation of Novel 2,3-dihydro-2-aryl-4-(4-isobutylphenyl)-1,5-benzothiazepine Derivatives as Anticancer and Anti-EGFR Tyrosine Kinase Agents

(2020) Afzal B. Shaik et al.   Anti-Cancer Agents in Medicinal Chemistry

Antimicrobial, Antioxidant, and Anticancer Activities of Some Novel Isoxazole Ring Containing Chalcone and Dihydropyrazole Derivatives

(2020) Afzal Shaik et al.   MOLECULES

5-Alkylamino-N-phenylpyrazine-2-carboxamides: Design, Preparation, and Antimycobacterial Evaluation

(2020) Weronika Ambrożkiewicz et al.   MOLECULES

Structure and characterization of organotin bimetallic supramolecular coordination polymers based on copper cyanide building blocks and pyrazine or pyrazine‐2‐carboxylic acid as new promising anticancer agents

(2020) Safaa Eldin H. Etaiw et al.   APPLIED ORGANOMETALLIC CHEMISTRY

2-Pyrazine-PPD, a novel dammarane derivative, showed anticancer activity by reactive oxygen species-mediate apoptosis and endoplasmic reticulum stress in gastric cancer cells

(2020) Xu De Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches

(2020) Eman S. Tantawy et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, characterization and antimicrobial studies of novel ONO donor hydrazone Schiff base complexes with some divalent metal (II) ions

(2020) R.S. Bhaskar et al.   Arabian Journal of Chemistry

Staphylococcus xylosus VITURAJ10: Pyrrolo [1,2α] pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl) (PPDHMP) producing, potential probiotic strain with antibacterial and anticancer activity

(2020) Upasana Mangrolia et al.   MICROBIAL PATHOGENESIS

A Facile Synthesis of Substituted 2‐(5‐(Benzylthio)‐1,3,4‐oxadiazol‐2‐yl)pyrazine Using Microwave Irradiation and Conventional Method with Antioxidant and Anticancer Activities

(2019) Sanjeev R. Patil et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies

(2019) Gulnar Mamedova et al.   BIOORGANIC CHEMISTRY

Expansion of chemical space based on a pyrrolo[1,2-a]pyrazine core: Synthesis and its anticancer activity in prostate cancer and breast cancer cells

(2019) Yohan Seo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Substituted N-(Pyrazin-2-yl)benzenesulfonamides; Synthesis, Anti-Infective Evaluation, Cytotoxicity, and In Silico Studies

(2019) Ghada Bouz et al.   MOLECULES

Syntheses of 1,5-Benzothiazepines: Part-50: 8-Substituted 2,3/2,5-dihydro-2,4-diaryl-1,5-benzothiazepines as Potential Antimicrobial Agents

(2018) Seema Pant et al.   ASIAN JOURNAL OF CHEMISTRY

A Convenient Synthesis, Reactions and Biological Activities of Some Novel Thieno[3,2-e]pyrazolo[3,4-b]pyrazine Compounds as Anti-microbial and Anti-inflammatory agents

(2018) Remon Zaki et al.   CURRENT ORGANIC SYNTHESIS

Synthesis of New Isoxazole-, Pyridazine-, Pyrimidopyrazines and Their Anti-Inflammatory and Analgesic Activity

(2018) Ameen A. Abu-Hashem et al.   Medicinal Chemistry

Chalcones and their pyrazine analogs: synthesis, inhibition of aldose reductase, antioxidant activity, and molecular docking study

(2018) Marta Kucerova-Chlupacova et al.   MONATSHEFTE FUR CHEMIE

Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents

(2018) Jan Zitko et al.   MOLECULES

Synthesis and anti-proliferative activity evaluation of novel benzo[ d ][1,3] dioxoles-fused 1,4-thiazepines

(2017) Liqiang Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and antiviral activities of 1,5-benzothiazepine derivatives containing pyridine moiety

(2017) Tianxian Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Activity of Novel 2,5-Dichloro-3-Acetylthiophene Chalcone Derivatives

(2017) Bontha Venkata Subrahmanya Lokesh et al.   Indian Journal of Pharmaceutical Education and Research

Synthesis of Indane-Based 1,5-Benzothiazepines Derived from 3-Phenyl-2,3-dihydro-1H -inden-1-one and Antimicrobial Studies Thereof

(2017) Satbir Mor et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis and biological evaluation of new 2-(6-alkyl-pyrazin-2-yl)-1H-benz[d]imidazoles as potent anti-inflammatory and antioxidant agents

(2017) Bhookya Shankar et al.   MEDICINAL CHEMISTRY RESEARCH

Design and synthesis of 5-methylpyrazine-2-carbohydrazide derivatives: A new anti-tubercular scaffold

(2017) P.B. Miniyar et al.   Arabian Journal of Chemistry

Novel Halogenated Pyrazine-Based Chalcones as Potential Antimicrobial Drugs

(2016) Marta Kucerova-Chlupacova et al.   MOLECULES

Novel Pyrazine Analogs of Chalcones: Synthesis and Evaluation of Their Antifungal and Antimycobacterial Activity

(2015) Marta Kucerova-Chlupacova et al.   MOLECULES

Alkylamino derivatives of N-benzylpyrazine-2-carboxamide: synthesis and antimycobacterial evaluation

(2015) Barbora Servusova-Vanaskova et al.   MedChemComm

Synthesis and biological evaluation of some novel pyrazole, isoxazole, benzoxazepine, benzothiazepine and benzodiazepine derivatives bearing an aryl sulfonate moiety as antimicrobial and anti-inflammatory agents

(2015) Babasaheb V. Kendre et al.   Arabian Journal of Chemistry

Synthesis and antimycobacterial evaluation of N-substituted 5-chloropyrazine-2-carboxamides

(2013) Barbora Servusová et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, Antimycobacterial Activity and In Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides

(2013) Jan Zitko et al.   MOLECULES

Evaluation of Structurally Diverse Benzoazepines Clubbed with Coumarins asMycobacterium tuberculosisAgents

(2012) Kuldip Upadhyay et al.   Chemical Biology & Drug Design

Heterocycles in drugs and drug discovery

(2012) A. Gomtsyan   Chemistry of Heterocyclic Compounds

Synthesis, reactions, and biological activity of 1,4-thiazepines and their fused aryl and heteroaryl derivatives: a review

(2011) Khairy A.M. El-Bayouki   Journal of Sulfur Chemistry

Synthesis and in vitro anti breast cancer activity of some novel 1,5-benzothiazepine derivatives

(2011) K.L. Ameta et al.   JOURNAL OF THE SERBIAN CHEMICAL SOCIETY

Solid-phase synthesis and biological evaluation of a parallel library of 2,3-dihydro-1,5-benzothiazepines

(2008) Farzana Latif Ansari et al.   BIOORGANIC & MEDICINAL CHEMISTRY

1,5-Benzothiazepine, a versatile pharmacophore: A review

(2008) Jitender B. Bariwal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The expedient synthesis of 1,5-benzothiazepines as a family of cytotoxic drugs

(2007) Kapil Arya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS