Clozapine’s multiple cellular mechanisms: What do we know after more than fifty years? A systematic review and critical assessment of translational mechanisms relevant for innovative strategies in treatment-resistant schizophrenia
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Title
Clozapine’s multiple cellular mechanisms: What do we know after more than fifty years? A systematic review and critical assessment of translational mechanisms relevant for innovative strategies in treatment-resistant schizophrenia
Authors
Keywords
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Journal
PHARMACOLOGY & THERAPEUTICS
Volume 236, Issue -, Pages 108236
Publisher
Elsevier BV
Online
2022-06-26
DOI
10.1016/j.pharmthera.2022.108236
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Note: Only part of the references are listed.- Present and future antipsychotic drugs: A systematic review of the putative mechanisms of action for efficacy and a critical appraisal under a translational perspective
- (2022) Andrea de Bartolomeis et al. PHARMACOLOGICAL RESEARCH
- Systematic literature review of schizophrenia clinical practice guidelines on acute and maintenance management with antipsychotics
- (2022) Christoph U. Correll et al. npj Schizophrenia
- Clozapine Induced Developmental and Cardiac Toxicity on Zebrafish Embryos by Elevating Oxidative Stress
- (2021) Feng Zhang et al. Cardiovascular Toxicology
- An update on the complex relationship between clozapine and pneumonia
- (2021) Georgios Schoretsanitis et al. Expert Review of Clinical Pharmacology
- 11C- and 18F-Radiotracers for In Vivo Imaging of the Dopamine System: Past, Present and Future
- (2021) Michael R. Kilbourn Biomedicines
- Effects of the Co‐Administration of MK‐801 and Clozapine MiRNA Expression Profiles in Rats
- (2021) Wenhui Huang et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Clozapine increases macrophage migration inhibitory factor (MIF) expression via increasing histone acetylation of MIF promoter in astrocytes
- (2021) Satoshi Okazaki et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Modulation of glutamatergic functional connectivity by a prototypical antipsychotic: Translational inference from a postsynaptic density immediate-early gene-based network analysis
- (2021) Annarita Barone et al. BEHAVIOURAL BRAIN RESEARCH
- The Antipsychotic Drug Clozapine Suppresses the RGS4 Polyubiquitylation and Proteasomal Degradation Mediated by the Arg/N-Degron Pathway
- (2021) Jun Hyoung Jeon et al. Neurotherapeutics
- White matter microstructure and structural networks in treatment-resistant schizophrenia patients after commencing clozapine treatment: A longitudinal diffusion imaging study
- (2021) Giulia Tronchin et al. PSYCHIATRY RESEARCH
- A ganglionic blocker and adrenoceptor ligands modify clozapine-induced insulin resistance
- (2021) Jessica W.Y. Yuen et al. PSYCHONEUROENDOCRINOLOGY
- Effects of antipsychotic drugs and potassium channel modulators on spectral properties of local field potentials in mouse hippocampus and pre-frontal cortex
- (2021) Dechuan Sun et al. NEUROPHARMACOLOGY
- Second-generation antipsychotics induce cardiotoxicity by disrupting spliceosome signaling: Implications from proteomic and transcriptomic analyses
- (2021) Jing Wang et al. PHARMACOLOGICAL RESEARCH
- Drug-Induced Idiosyncratic Agranulocytosis - Infrequent but Dangerous
- (2021) Bernd Rattay et al. Frontiers in Pharmacology
- Characteristics of the corpus callosum in chronic schizophrenia treated with clozapine or risperidone and those never-treated
- (2021) Bo Tao et al. BMC Psychiatry
- Pharmacotherapy of schizophrenia: immunological aspects and potential role of immunotherapy
- (2021) Prerna Chauhan et al. Expert Review of Neurotherapeutics
- Relationship of selective complement markers with schizophrenia
- (2021) Abdull Jalil Mohd Asyraf et al. JOURNAL OF NEUROIMMUNOLOGY
- A preliminary genetic association study of GAD1 and GABAB receptor genes in patients with treatment-resistant schizophrenia
- (2021) Atsuhiro Miyazawa et al. MOLECULAR BIOLOGY REPORTS
- Treatment-resistant schizophrenia: Addressing white matter integrity, intracortical glutamate levels, clinical and cognitive profiles between early- and adult-onset patients
- (2021) Marta Matrone et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Clozapine protects adult neural stem cells from ketamine-induced cell death in correlation with decreased apoptosis and autophagy
- (2020) Mathias Lundberg et al. BIOSCIENCE REPORTS
- Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis
- (2020) Katharina Robichon et al. Journal of Neuroinflammation
- Clozapine reliably increases the motivation for food: parsing the role of the 5-HT2c and H1 receptors
- (2020) Andrew R. Abela et al. PSYCHOPHARMACOLOGY
- Genetic associations with clozapine-induced myocarditis in patients with schizophrenia
- (2020) Paul Lacaze et al. Translational Psychiatry
- Activation of Astroglial Connexin Is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine
- (2020) Kouji Fukuyama et al. Cells
- Glutamatergic neurometabolites and cortical thickness in treatment-resistant schizophrenia: Implications for glutamate-mediated excitotoxicity
- (2020) Parita Shah et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Binding of clozapine to the GABAB receptor: clinical and structural insights
- (2020) Pramod C. Nair et al. MOLECULAR PSYCHIATRY
- Progressive subcortical volume loss in treatment-resistant schizophrenia patients after commencing clozapine treatment
- (2020) Giulia Tronchin et al. NEUROPSYCHOPHARMACOLOGY
- A Rational Use of Clozapine Based on Adverse Drug Reactions, Pharmacokinetics, and Clinical Pharmacopsychology
- (2020) Jose de Leon et al. PSYCHOTHERAPY AND PSYCHOSOMATICS
- Tricyclic antipsychotics promote adipogenic gene expression to potentiate preadipocyte differentiation in vitro
- (2020) Christopher M. Cottingham et al. Human Cell
- Retinoid X Receptor α Regulates DHA-Dependent Spinogenesis and Functional Synapse Formation In Vivo
- (2020) Huateng Cao et al. Cell Reports
- Characteristics of gray matter alterations in never-treated and treated chronic schizophrenia patients
- (2020) Nian Liu et al. Translational Psychiatry
- Glycine Signaling in the Framework of Dopamine-Glutamate Interaction and Postsynaptic Density. Implications for Treatment-Resistant Schizophrenia
- (2020) Andrea de Bartolomeis et al. Frontiers in Psychiatry
- Atypical antipsychotic clozapine binds fibrinogen and affects fibrin formation
- (2020) Nikola Gligorijević et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Clozapine modulates retinoid homeostasis in human brain and normalizes serum retinoic acid deficit in patients with schizophrenia
- (2020) Francesca Regen et al. MOLECULAR PSYCHIATRY
- Alpha 7 nicotinic receptor agonist and positive allosteric modulators improved social and molecular deficits of MK-801 model of schizophrenia in rats
- (2020) G. Unal et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Muscarinic M1 and M4 receptors: Hypothesis driven drug development for schizophrenia
- (2020) Brian Dean et al. PSYCHIATRY RESEARCH
- Antipsychotics inhibit the mitochondrial bioenergetics of pancreatic beta cells isolated from CD1 mice
- (2020) Ekramy Elmorsy et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Safety and tolerability of antipsychotic agents in neurodevelopmental disorders: a systematic review
- (2020) Felice Iasevoli et al. Expert Opinion On Drug Safety
- Association between N-desmethylclozapine and clozapine-induced sialorrhea: Involvement of increased nocturnal salivary secretion via muscarinic receptors by N-desmethylclozapine
- (2020) Shuhei Ishikawa et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Effectiveness of clozapine on quality of life and functioning in patients with treatment-resistant schizophrenia
- (2020) Meha Verma et al. NORDIC JOURNAL OF PSYCHIATRY
- Comparative Effectiveness of Antipsychotics for Risk of Attempted or Completed Suicide Among Persons With Schizophrenia
- (2020) Heidi Taipale et al. SCHIZOPHRENIA BULLETIN
- α7 nicotinic receptor agonist and positive allosteric modulators differently improved schizophrenia-like cognitive deficits in male rats
- (2020) Gokhan Unal et al. BEHAVIOURAL BRAIN RESEARCH
- Could N‐acetylcysteine improve the safety of clozapine?
- (2020) Basile Chrétien et al. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
- Effects of several atypical antipsychotics closapine, sertindole or ziprasidone on hepatic antioxidant enzymes: Possible role in drug-induced liver dysfunction
- (2020) Lena Platanić Arizanović et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
- Association between anticholinergic burden and anticholinergic adverse outcomes in the elderly: Pharmacological basis of their predictive value for adverse outcomes
- (2020) Marta Lavrador et al. PHARMACOLOGICAL RESEARCH
- Relationship of Change in Plasma Clozapine/N-desmethylclozapine Ratio with Cognitive Performance in Patients with Schizophrenia
- (2020) Royun Park et al. Psychiatry Investigation
- Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia
- (2020) Grant McQueen et al. SCHIZOPHRENIA BULLETIN
- Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity
- (2020) Ege Arzuk et al. TOXICOLOGY
- The differential actions of clozapine and other antipsychotic drugs on the translocation of dopamine D2 receptors to the cell-surface
- (2019) Joseph M. Schrader et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synaptic retinoic acid receptor signaling mediates mTOR-dependent metaplasticity that controls hippocampal learning
- (2019) Yu-Tien Hsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synapse Formation: From Cellular and Molecular Mechanisms to Neurodevelopmental and Neurodegenerative Disorders
- (2019) Shadab Batool et al. JOURNAL OF NEUROPHYSIOLOGY
- Association between serum lipids and antipsychotic response in schizophrenia
- (2019) David D. Kim et al. Current Neuropharmacology
- Treatment Recommendations for Tardive Dyskinesia
- (2019) Lucia Ricciardi et al. CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
- Dimers of serotonin receptors: Impact on ligand affinity and signaling
- (2019) Luc Maroteaux et al. BIOCHIMIE
- Clozapine administration enhanced functional recovery after cuprizone demyelination
- (2019) Nikki Templeton et al. PLoS One
- Hypofunctional Dopamine Uptake and Antipsychotic Treatment-Resistant Schizophrenia
- (2019) Davide Amato et al. Frontiers in Psychiatry
- Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis
- (2019) Maximilian Huhn et al. LANCET
- Antipsychotics differentially regulate insulin, energy sensing, and inflammation pathways in hypothalamic rat neurons
- (2019) Chantel Kowalchuk et al. PSYCHONEUROENDOCRINOLOGY
- Neonatal exposure to an inflammatory cytokine, epidermal growth factor, results in the deficits of mismatch negativity in rats
- (2019) Eiichi Jodo et al. Scientific Reports
- Association With Hospitalization and All-Cause Discontinuation Among Patients With Schizophrenia on Clozapine vs Other Oral Second-Generation Antipsychotics
- (2019) Takahiro Masuda et al. JAMA Psychiatry
- Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases
- (2019) Yutaro Kobayashi et al. Translational Psychiatry
- Clozapine Normalizes a Glutamatergic Transmission Abnormality Induced by an Impaired NMDA Receptor in the Thalamocortical Pathway via the Activation of a Group III Metabotropic Glutamate Receptor
- (2019) Fukuyama et al. Biomolecules
- Clozapine-associated secondary antibody deficiency
- (2019) Mark J. Ponsford et al. Current Opinion in Allergy and Clinical Immunology
- The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans
- (2019) G. M. Leggio et al. MOLECULAR PSYCHIATRY
- Translating preclinical findings in clinically relevant new antipsychotic targets: focus on the glutamatergic postsynaptic density. Implications for treatment resistant schizophrenia
- (2019) Andrea de Bartolomeis et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Antidepressant Drugs Correct the Imbalance Between proBDNF/p75NTR/Sortilin and Mature BDNF/TrkB in the Brain of Mice with Chronic Stress
- (2019) C. R. Yang et al. NEUROTOXICITY RESEARCH
- Clozapine Rechallenge After Major Adverse Effects
- (2018) Peter Manu et al. AMERICAN JOURNAL OF THERAPEUTICS
- Tardive Dyskinesia Associated with Atypical Antipsychotics: Prevalence, Mechanisms and Management Strategies
- (2018) Katharina Stegmayer et al. CNS DRUGS
- Antipsychotic drugs for patients with schizophrenia and predominant or prominent negative symptoms: a systematic review and meta-analysis
- (2018) Marc Krause et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Effects of the antipsychotics haloperidol, clozapine, and aripiprazole on the dendritic spine
- (2018) Manabu Takaki et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Clinical risk factors for the development of tardive dyskinesia
- (2018) Marco Solmi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier-Mediated Process
- (2018) David Dickens et al. MOLECULAR PHARMACEUTICS
- Positive allosteric modulation of M 1 and M 4 muscarinic receptors as potential therapeutic treatments for schizophrenia
- (2018) Samantha E. Yohn et al. NEUROPHARMACOLOGY
- Beta and Gamma Oscillations in Prefrontal Cortex During NMDA Hypofunction: An In Vitro Model of Schizophrenia Features
- (2018) Beatriz Rebollo et al. NEUROSCIENCE
- Dopamine, the antipsychotic molecule: A perspective on mechanisms underlying antipsychotic response variability
- (2018) Davide Amato et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Gene–gene interaction between DRD4 and COMT modulates clinical response to clozapine in treatment-resistant schizophrenia
- (2018) Veera M. Rajagopal et al. Pharmacogenetics and Genomics
- Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences
- (2018) Stefano Aringhieri et al. PHARMACOLOGY & THERAPEUTICS
- The antipsychotic agent clozapine induces autophagy via the AMPK-ULK1-Beclin1 signaling pathway in the rat frontal cortex
- (2018) Se Hyun Kim et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Reversal of Dopamine Supersensitivity as a Mechanism of Action of Clozapine
- (2018) David D. Kim et al. PSYCHOTHERAPY AND PSYCHOSOMATICS
- Inflammation in Schizophrenia: Pathogenetic Aspects and Therapeutic Considerations
- (2018) Norbert Müller SCHIZOPHRENIA BULLETIN
- Repeated Clozapine Increases the Level of Serotonin 5-HT1AR Heterodimerization with 5-HT2A or Dopamine D2 Receptors in the Mouse Cortex
- (2018) Marta Szlachta et al. Frontiers in Molecular Neuroscience
- Switching From Tobacco Smoking to Electronic Cigarettes and the Impact on Clozapine Levels
- (2018) Thomas Kocar et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Clozapine attenuates mitochondrial burdens and abnormal behaviors elicited by phencyclidine in mice via inhibition of p47phox; Possible involvements of phosphoinositide 3-kinase/Akt signaling
- (2018) Hai-Quyen Tran et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Clozapine, ziprasidone, and sertindole-induced morphological changes in the rat heart and their relationship to antioxidant enzymes function
- (2018) Aleksandra Nikolić-Kokić et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
- A dopaminergic mechanism of antipsychotic drug efficacy, failure, and failure reversal: the role of the dopamine transporter
- (2018) Davide Amato et al. MOLECULAR PSYCHIATRY
- Current Concepts and Treatments of Schizophrenia
- (2018) Piotr Stępnicki et al. MOLECULES
- An evaluation of the differences in DNA damage in lymphocytes and repair efficiencies in patients with schizophrenia and schizoaffective disorder
- (2018) Osman Zulkif Topak et al. SCHIZOPHRENIA RESEARCH
- Clinical evaluation of functional capacity in treatment resistant schizophrenia patients: Comparison and differences with non-resistant schizophrenia patients
- (2018) Felice Iasevoli et al. SCHIZOPHRENIA RESEARCH
- Tardive dyskinesia risk with first- and second-generation antipsychotics in comparative randomized controlled trials: a meta-analysis
- (2018) Maren Carbon et al. World Psychiatry
- The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice
- (2018) Daniel F. Manvich et al. Scientific Reports
- Reduced activity and connectivity of left amygdala in patients with schizophrenia treated with clozapine or olanzapine
- (2018) Daniela Mier et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Retinoic Acid Receptor RARα-Dependent Synaptic Signaling Mediates Homeostatic Synaptic Plasticity at the Inhibitory Synapses of Mouse Visual Cortex
- (2018) Lei R. Zhong et al. JOURNAL OF NEUROSCIENCE
- 5-HT2A deletion protects against Clozapine-induced hyperglycemia
- (2018) Radhika Sudhir Joshi et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Polygenic disruption of retinoid signalling in schizophrenia and a severe cognitive deficit subtype
- (2018) William R. Reay et al. MOLECULAR PSYCHIATRY
- Selective adrenergic alpha2C receptor antagonist ameliorates acute phencyclidine-induced schizophrenia-like social interaction deficits in rats
- (2018) Katja Savolainen et al. PSYCHOPHARMACOLOGY
- Hydrogen Sulfide Affects Radical Formation in the Hippocampus of LPS Treated Rats and the Effect of Antipsychotics on Hydrogen Sulfide Forming Enzymes in Human Cell Lines
- (2018) Olaf Sommer et al. Frontiers in Psychiatry
- N-3 polyunsaturated fatty acids and clozapine abrogates poly I: C-induced immune alterations in primary hippocampal neurons
- (2018) Bruna Mara Machado Ribeiro et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Histaminergic gene polymorphisms associated with sedation in clozapine-treated patients
- (2017) Anssi Solismaa et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Clozapine as the most efficacious antipsychotic for activating ERK 1/2 kinases: Role of 5-HT 2A receptor agonism
- (2017) Stefano Aringhieri et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Clozapine induced gastrointestinal hypomotility: A potentially life threatening adverse event. A review of the literature
- (2017) Stephen West et al. GENERAL HOSPITAL PSYCHIATRY
- Tardive Dyskinesia Prevalence in the Period of Second-Generation Antipsychotic Use
- (2017) Maren Carbon et al. JOURNAL OF CLINICAL PSYCHIATRY
- Return of D4 Dopamine Receptor Antagonists in Drug Discovery
- (2017) Craig W. Lindsley et al. JOURNAL OF MEDICINAL CHEMISTRY
- Protein components of post-synaptic density lattice, a backbone structure for type I excitatory synapses
- (2017) Tatsuo Suzuki et al. JOURNAL OF NEUROCHEMISTRY
- CSF GABA is reduced in first-episode psychosis and associates to symptom severity
- (2017) F Orhan et al. MOLECULAR PSYCHIATRY
- Clozapine as a Model for Antipsychotic Development
- (2017) Frederick C. Nucifora et al. Neurotherapeutics
- New therapeutic opportunities for 5-HT2 receptor ligands
- (2017) Luc Maroteaux et al. PHARMACOLOGY & THERAPEUTICS
- Re-arrangements of gene transcripts at glutamatergic synapses after prolonged treatments with antipsychotics: A putative link with synaptic remodeling
- (2017) Elisabetta Filomena Buonaguro et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Chemogenetics revealed: DREADD occupancy and activation via converted clozapine
- (2017) Juan L. Gomez et al. SCIENCE
- Developmental effects of antipsychotic drugs on serotonin receptor subtypes
- (2017) Yong Kee Choi et al. SYNAPSE
- The role of oxidative stress in antipsychotics induced ovarian toxicity
- (2017) Ekramy Elmorsy et al. TOXICOLOGY IN VITRO
- Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells
- (2017) Ekramy Elmorsy et al. TOXICOLOGY LETTERS
- Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors
- (2017) David A. Sykes et al. Nature Communications
- Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation
- (2017) Noelia A. Massari et al. Oncotarget
- Chemistry-based molecular signature underlying the atypia of clozapine
- (2017) T Cardozo et al. Translational Psychiatry
- Cortical high gamma network oscillations and connectivity: a translational index for antipsychotics to normalize aberrant neurophysiological activity
- (2017) A. Ahnaou et al. Translational Psychiatry
- Therapeutic Potential of Selectively Targeting the α2C-Adrenoceptor in Cognition, Depression, and Schizophrenia—New Developments and Future Perspective
- (2017) Madeleine Monique Uys et al. Frontiers in Psychiatry
- Sodium Benzoate, a D-Amino Acid Oxidase Inhibitor, Added to Clozapine for the Treatment of Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled Trial
- (2017) Chieh-Hsin Lin et al. BIOLOGICAL PSYCHIATRY
- Comparing the effect of clozapine and risperidone on cue reactivity in male patients with schizophrenia and a cannabis use disorder: A randomized fMRI study
- (2017) Marise W.J. Machielsen et al. SCHIZOPHRENIA RESEARCH
- Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats
- (2017) Xuemei Liu et al. Scientific Reports
- VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body
- (2017) Hideaki Yamamoto et al. Scientific Reports
- Y-QA31, a novel dopamine D3 receptor antagonist, exhibits antipsychotic-like properties in preclinical animal models of schizophrenia
- (2016) Xue Sun et al. ACTA PHARMACOLOGICA SINICA
- Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis
- (2016) Dan Siskind et al. BRITISH JOURNAL OF PSYCHIATRY
- Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells
- (2016) Sonam Dolma et al. CANCER CELL
- Targeting Retinoid Receptors to Treat Schizophrenia: Rationale and Progress to Date
- (2016) Vladimir Lerner et al. CNS DRUGS
- Antipsychotic Drug-Induced Somnolence: Incidence, Mechanisms, and Management
- (2016) Fang Fang et al. CNS DRUGS
- Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol
- (2016) Masahiko Kawano et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Phencyclidine-induced disruption of oscillatory activity in prefrontal cortex: Effects of antipsychotic drugs and receptor ligands
- (2016) L. Lladó-Pelfort et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- The fast-off hypothesis revisited: A functional kinetic study of antipsychotic antagonism of the dopamine D2 receptor
- (2016) Kristoffer Sahlholm et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Genetic association analysis of N-methyl-d-aspartate receptor subunit geneGRIN2Band clinical response to clozapine
- (2016) Danielle L. Taylor et al. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
- Dopamine D2and serotonin 5-HT1Areceptor interaction in the context of the effects of antipsychotics -in vitrostudies
- (2016) Sylwia Łukasiewicz et al. JOURNAL OF NEUROCHEMISTRY
- Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase
- (2016) Lulu Jiang et al. Journal of Neuroinflammation
- Effects of prolonged antipsychotic administration on neuregulin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect
- (2016) Ruili Dang et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- The microtubular cytoskeleton of olfactory neurons derived from patients with schizophrenia or with bipolar disorder: Implications for biomarker characterization, neuronal physiology and pharmacological screening
- (2016) G. Benítez-King et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway
- (2016) Zhiwen Zeng et al. MOLECULAR NEUROBIOLOGY
- DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
- (2016) Patrick Aldrin-Kirk et al. NEURON
- Stathmin reduction and cytoskeleton rearrangement in rat nucleus accumbens in response to clozapine and risperidone treatment – Comparative proteomic study
- (2016) S. Kedracka-Krok et al. NEUROSCIENCE
- Preliminary evidence for association of genome-wide significant DRD2 schizophrenia risk variant with clozapine response
- (2016) Eric Huang et al. PHARMACOGENOMICS
- Antipsychotic drugs induce cell cytoskeleton reorganization in glial and neuronal cells via Rho/Cdc42 signal pathway
- (2016) Mao-Liang Chen et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Treatment resistant schizophrenia is associated with the worst community functioning among severely-ill highly-disabling psychiatric conditions and is the most relevant predictor of poorer achievements in functional milestones
- (2016) Felice Iasevoli et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The α2C-adrenoceptor antagonist, ORM-10921, has antipsychotic-like effects in social isolation reared rats and bolsters the response to haloperidol
- (2016) Madeleine Uys et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Pharmacogenetic Associations of Antipsychotic Drug-Related Weight Gain: A Systematic Review and Meta-analysis
- (2016) Jian-Ping Zhang et al. SCHIZOPHRENIA BULLETIN
- Antioxidant properties of atypical antipsychotic drugs used in the treatment of schizophrenia
- (2016) Izabela Sadowska-Bartosz et al. SCHIZOPHRENIA RESEARCH
- The role of the ITIH3 rs2535629 variant in antipsychotic response
- (2016) E.J. Brandl et al. SCHIZOPHRENIA RESEARCH
- Involvement of the histamine H 4 receptor in clozapine-induced hematopoietic toxicity: Vulnerability under granulocytic differentiation of HL-60 cells
- (2016) Aya Goto et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- The Role of Clozapine in Treatment-Resistant Schizophrenia
- (2016) John M. Kane et al. JAMA Psychiatry
- Efficacy, Acceptability, and Tolerability of Antipsychotics in Treatment-Resistant Schizophrenia
- (2016) Myrto T. Samara et al. JAMA Psychiatry
- Clozapine modifies the differentiation program of human adipocytes inducing browning
- (2016) E Kristóf et al. Translational Psychiatry
- Clozapine-induced myocarditis, a widely overlooked adverse reaction
- (2015) K. J. Ronaldson et al. ACTA PSYCHIATRICA SCANDINAVICA
- Attention Must Be Paid: The Association of Plasma Clozapine/NDMC Ratio With Working Memory
- (2015) Herbert Y. Meltzer AMERICAN JOURNAL OF PSYCHIATRY
- L-745,870 reduces the expression of abnormal involuntary movements in the 6-OHDA-lesioned rat
- (2015) Philippe Huot et al. BEHAVIOURAL PHARMACOLOGY
- Bioenergetic disruption of human micro-vascular endothelial cells by antipsychotics
- (2015) Ekramy Elmorsy et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Genetic Risk for Schizophrenia: Convergence on Synaptic Pathways Involved in Plasticity
- (2015) Jeremy Hall et al. BIOLOGICAL PSYCHIATRY
- Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria
- (2015) Nino Natsvlishvili et al. BMC BIOCHEMISTRY
- The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7receptors
- (2015) K W Andressen et al. BRITISH JOURNAL OF PHARMACOLOGY
- Response to clozapine in a clinically identifiable subtype of schizophrenia
- (2015) Nancy J. Butcher et al. BRITISH JOURNAL OF PSYCHIATRY
- Developmental Trajectories of Auditory Cortex Synaptic Structures and Gap-Prepulse Inhibition of Acoustic Startle Between Early Adolescence and Young Adulthood in Mice
- (2015) Caitlin E. Moyer et al. CEREBRAL CORTEX
- Dopamine D4 Receptor Antagonists for the Treatment of Cocaine Use Disorders
- (2015) Jack Bergman et al. CNS & Neurological Disorders-Drug Targets
- Atypical antipsychotics and inverse agonism at 5-HT2 receptors
- (2015) Laura Sullivan et al. CURRENT PHARMACEUTICAL DESIGN
- 5-HT2 receptors modulate the expression of antipsychotic-induced dopamine supersensitivity
- (2015) Alexandra Charron et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Role of serotonin 5-HT2C and histamine H1 receptors in antipsychotic-induced diabetes: A pharmacoepidemiological-pharmacodynamic study in VigiBase
- (2015) François Montastruc et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Progressive recruitment of cortical and striatal regions by inducible postsynaptic density transcripts after increasing doses of antipsychotics with different receptor profiles: Insights for psychosis treatment
- (2015) Andrea de Bartolomeis et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Sleep EEG and Spindle Characteristics After Combination Treatment With Clozapine in Drug-Resistant Schizophrenia
- (2015) Hara Tsekou et al. JOURNAL OF CLINICAL NEUROPHYSIOLOGY
- Association Study of GABAA α2 Receptor Subunit Gene Variants in Antipsychotic-Associated Weight Gain
- (2015) Clement C.H. Zai et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Clozapine influences cytoskeleton structure and calcium homeostasis in rat cerebral cortex and has a different proteomic profile than risperidone
- (2015) Sylwia Kedracka-Krok et al. JOURNAL OF NEUROCHEMISTRY
- Increased orbitofrontal cortex activation associated with “pro-obsessive” antipsychotic treatment in patients with schizophrenia
- (2015) JOURNAL OF PSYCHIATRY & NEUROSCIENCE
- Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
- (2015) NATURE NEUROSCIENCE
- Different pharmacology of N-desmethylclozapine at human and rat M2 and M4 mAChRs in neocortex
- (2015) S. Gigout et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model
- (2015) A Ghoshal et al. NEUROPSYCHOPHARMACOLOGY
- Progressive Brain Atrophy and Cortical Thinning in Schizophrenia after Commencing Clozapine Treatment
- (2015) Mohamed Ahmed et al. NEUROPSYCHOPHARMACOLOGY
- The muscarinic system, cognition and schizophrenia
- (2015) Sean P. Carruthers et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Hypothalamic–pituitary–adrenal system, neurotrophic factors and clozapine response
- (2015) Marina Mitjans et al. Pharmacogenetics and Genomics
- COMT Val158Met and 5-HT1A-R -1019 C/G polymorphisms: effects on the negative symptom response to clozapine
- (2015) Marta Bosia et al. PHARMACOGENOMICS
- Complement 3 and metabolic syndrome induced by clozapine: a cross-sectional study and retrospective cohort analysis
- (2015) C Zhang et al. PHARMACOGENOMICS JOURNAL
- Clozapine and GABA transmission in schizophrenia disease models
- (2015) William T. O'Connor et al. PHARMACOLOGY & THERAPEUTICS
- Clozapine induces chloride channel-4 expression through PKA activation and modulates CDK5 expression in SH-SY5Y and U87 cells
- (2015) Songhee Jeon et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Meta-analysis of dopamine receptor D1 rs4532 polymorphism and susceptibility to antipsychotic treatment response
- (2015) Luiza P.R. de Matos et al. PSYCHIATRY RESEARCH
- Histamine H1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers
- (2015) Hirotoshi Sato et al. PSYCHOPHARMACOLOGY
- Changes in cholinergic and glutamatergic markers in the striatum from a sub-set of subjects with schizophrenia
- (2015) Brian Dean et al. SCHIZOPHRENIA RESEARCH
- Emotion processing in treatment-resistant schizophrenia patients treated with clozapine: An fMRI study
- (2015) Stéphane Potvin et al. SCHIZOPHRENIA RESEARCH
- Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta-analysis
- (2015) Davy Vancampfort et al. World Psychiatry
- Schizophrenia
- (2015) René S. Kahn et al. Nature Reviews Disease Primers
- Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood–brain barrier
- (2014) Ekramy Elmorsy et al. BRAIN RESEARCH
- Clozapine-Induced Cardiotoxicity: Role of Oxidative Stress, Tumour Necrosis Factor Alpha and NF-κβ
- (2014) Basel A. Abdel-Wahab et al. Cardiovascular Toxicology
- Clozapine Promotes the Proliferation of Granulocyte Progenitors in the Bone Marrow Leading to Increased Granulopoiesis and Neutrophilia in Rats
- (2014) Alexandra R. Lobach et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Pharmacological Strategies for the Management of Levodopa-Induced Dyskinesia in Patients with Parkinson’s Disease
- (2014) Eva Schaeffer et al. CNS DRUGS
- Weight gain and antipsychotics: a drug safety review
- (2014) Richard Musil et al. Expert Opinion On Drug Safety
- Chronic administration of antipsychotics attenuates ongoing and ketamine-induced increases in cortical γ oscillations
- (2014) Paul M. Anderson et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- De novo mutations in schizophrenia implicate synaptic networks
- (2014) Menachem Fromer et al. NATURE
- Improving cognition in schizophrenia with antipsychotics that elicit neurogenesis through 5-HT1A receptor activation
- (2014) Rudy Schreiber et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Effects of Selective Activation of M1 and M4 Muscarinic Receptors on Object Recognition Memory Performance in Rats
- (2014) Claire R. Galloway et al. PHARMACOLOGY
- Regulation of postsynaptic plasticity genes' expression and topography by sustained dopamine perturbation and modulation by acute memantine: Relevance to schizophrenia
- (2014) Felice Iasevoli et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Effect of clozapine on white matter integrity in patients with schizophrenia: A diffusion tensor imaging study
- (2014) Elcin Ozcelik-Eroglu et al. PSYCHIATRY RESEARCH-NEUROIMAGING
- Effects of central activation of serotonin 5-HT2A/2C or dopamine D2/3 receptors on the acute and repeated effects of clozapine in the conditioned avoidance response test
- (2014) Min Feng et al. PSYCHOPHARMACOLOGY
- Greater clinical and cognitive improvement with clozapine and risperidone associated with a thinner cortex at baseline in first-episode schizophrenia
- (2014) Vicente Molina et al. SCHIZOPHRENIA RESEARCH
- Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles
- (2014) Jacqueline I. Goldstein et al. Nature Communications
- Antipsychotic Induced Weight Gain: Genetics, Epigenetics, and Biomarkers Reviewed
- (2014) Tahireh A. Shams et al. Current Psychiatry Reports
- Meta-analysis: the effects of smoking on the disposition of two commonly used antipsychotic agents, olanzapine and clozapine
- (2014) Yoshiyuki Tsuda et al. BMJ Open
- Hemichannels: new roles in astroglial function
- (2014) Juan A. Orellana et al. Frontiers in Physiology
- Effects of Antipsychotics on the Inflammatory Response System of Patients with Schizophrenia in Peripheral Blood Mononuclear Cell Cultures
- (2014) Mamun Al-Amin et al. Clinical Psychopharmacology and Neuroscience
- Clozapine, a Fast-Off-D2 Antipsychotic
- (2013) Philip Seeman ACS Chemical Neuroscience
- Classics in Chemical Neuroscience: Clozapine
- (2013) Cody J. Wenthur et al. ACS Chemical Neuroscience
- Diverse regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes
- (2013) Hideaki Tagashira et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Pharmacological Characterisation of a Structurally Novel α2C-Adrenoceptor Antagonist ORM-10921 and its Effects in Neuropsychiatric Models
- (2013) Jukka Sallinen et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Effects of risperidone, clozapine and the 5-HT6 antagonist GSK-742457 on PCP-induced deficits in reversal learning in the two-lever operant task in male Sprague Dawley rats
- (2013) N.M.W.J. de Bruin et al. BEHAVIOURAL BRAIN RESEARCH
- Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes
- (2013) Dasiel O. Borroto-Escuela et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Therapeutic potential of histamine H4receptor agonists in triple-negative human breast cancer experimental model
- (2013) Diego J Martinel Lamas et al. BRITISH JOURNAL OF PHARMACOLOGY
- Dynamic Interaction between Sigma-1 Receptor and Kv1.2 Shapes Neuronal and Behavioral Responses to Cocaine
- (2013) Saïd Kourrich et al. CELL
- Complexity of dopamine metabolism
- (2013) Johannes Meiser et al. Cell Communication and Signaling
- Second Generation Antipsychotic-Induced Type 2 Diabetes: A Role for the Muscarinic M3 Receptor
- (2013) Katrina Weston-Green et al. CNS DRUGS
- Treatment of adolescents with early-onset schizophrenia spectrum disorders
- (2013) Benno G. Schimmelmann et al. CURRENT OPINION IN PSYCHIATRY
- The potential role of dopamine D3 receptor neurotransmission in cognition
- (2013) Shinichiro Nakajima et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor
- (2013) Yuki Aoyama et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- The Retinoid X Receptor Agonist Bexarotene Relieves Positive Symptoms of Schizophrenia
- (2013) Vladimir Lerner et al. JOURNAL OF CLINICAL PSYCHIATRY
- Termination of Clozapine Treatment Due to Medical Reasons
- (2013) Jimmi Nielsen et al. JOURNAL OF CLINICAL PSYCHIATRY
- Do Atypical Antipsychotics Really Enhance Smoking Reduction More Than Typical Ones?
- (2013) Bo-Jian Wu et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Optimal Extent of Dopamine D2 Receptor Occupancy by Antipsychotics for Treatment of Dopamine Supersensitivity Psychosis and Late-Onset Psychosis
- (2013) Masaomi Iyo et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Antitumor activity of histamine and clozapine in a mouse experimental model of human melanoma
- (2013) Noelia A. Massari et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Increases in triglyceride levels are associated with clinical response to clozapine treatment
- (2013) John Lally et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Glutamatergic Postsynaptic Density Protein Dysfunctions in Synaptic Plasticity and Dendritic Spines Morphology: Relevance to Schizophrenia and Other Behavioral Disorders Pathophysiology, and Implications for Novel Therapeutic Approaches
- (2013) Andrea de Bartolomeis et al. MOLECULAR NEUROBIOLOGY
- Synaptic regulation of affective behaviors; role of BDNF
- (2013) Ipe Ninan NEUROPHARMACOLOGY
- Chronic effects of clozapine administration on insulin resistance in rats: Evidence for adverse metabolic effects
- (2013) Mohamed M. El-Seweidy et al. PATHOLOGY RESEARCH AND PRACTICE
- Acutely administered antipsychotic drugs are highly selective for dopamine D2 over D3 receptors
- (2013) Patrick N. McCormick et al. PHARMACOLOGICAL RESEARCH
- Clozapine-Induced Mitochondria Alterations and Inflammation in Brain and Insulin-Responsive Cells
- (2013) Verόnica Contreras-Shannon et al. PLoS One
- Cocaine Inhibits Dopamine D2 Receptor Signaling via Sigma-1-D2 Receptor Heteromers
- (2013) Gemma Navarro et al. PLoS One
- Effects of the Selective 5-HT7 Receptor Antagonist SB-269970 and Amisulpride on Ketamine-Induced Schizophrenia-like Deficits in Rats
- (2013) Agnieszka Nikiforuk et al. PLoS One
- Different effects of the NMDA receptor antagonists ketamine, MK-801, and memantine on postsynaptic density transcripts and their topography: Role of Homer signaling, and implications for novel antipsychotic and pro-cognitive targets in psychosis
- (2013) Andrea de Bartolomeis et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Differential cognitive performances between schizophrenic responders and non-responders to antipsychotics: Correlation with course of the illness, psychopathology, attitude to the treatment and antipsychotics doses
- (2013) Andrea de Bartolomeis et al. PSYCHIATRY RESEARCH
- The CYP1A2 –163C>A polymorphism is associated with clozapine-induced generalized tonic-clonic seizures in Brazilian schizophrenia patients
- (2013) Fabiana Barzotti Kohlrausch et al. PSYCHIATRY RESEARCH
- Genetic variation in BDNF is associated with antipsychotic treatment resistance in patients with schizophrenia
- (2013) Jian-Ping Zhang et al. SCHIZOPHRENIA RESEARCH
- NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia
- (2013) Melissa A. Snyder et al. Frontiers in Cellular Neuroscience
- Tobacco smoking in treatment-resistant schizophrenia patients is associated with impaired cognitive functioning, more severe negative symptoms, and poorer social adjustment
- (2013) Felice Iasevoli et al. Neuropsychiatric Disease and Treatment
- Update on Typical and Atypical Antipsychotic Drugs
- (2012) Herbert Y. Meltzer Annual Review of Medicine
- Functional Consequences of Mutations in Postsynaptic Scaffolding Proteins and Relevance to Psychiatric Disorders
- (2012) Jonathan T. Ting et al. Annual Review of Neuroscience
- Real-world effectiveness of clozapine in patients with bipolar disorder: results from a 2-year mirror-image study
- (2012) Jimmi Nielsen et al. BIPOLAR DISORDERS
- Social isolation rearing induces mitochondrial, immunological, neurochemical and behavioural deficits in rats, and is reversed by clozapine or N-acetyl cysteine
- (2012) Marisa Möller et al. BRAIN BEHAVIOR AND IMMUNITY
- First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3and D3receptors
- (2012) Steffen B Schulz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Clozapine, but not haloperidol, enhances glial d-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes
- (2012) Shunske Tanahashi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Clozapine for the treatment of schizophrenia
- (2012) Eric Fakra et al. EXPERT OPINION ON PHARMACOTHERAPY
- Clozapine inhibits Th1 cell differentiation and causes the suppression of IFN-γ production in peripheral blood mononuclear cells
- (2012) Mao-Liang Chen et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Antipsychotic compounds differentially modulate high-frequency oscillations in the rat nucleus accumbens: a comparison of first- and second-generation drugs
- (2012) Maciej Olszewski et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- A systematic review of the evidence of clozapine's anti-aggressive effects
- (2012) Catherine Frogley et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function
- (2012) José L. Moreno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Predictors of Clozapine Response in Patients With Treatment-Refractory Schizophrenia
- (2012) Jimmi Nielsen et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Association Study of 27 Annotated Genes for Clozapine Pharmacogenetics
- (2012) Seung-Tae Lee et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- The Importance of the NRG-1/ErbB4 Pathway for Synaptic Plasticity and Behaviors Associated with Psychiatric Disorders
- (2012) A. Shamir et al. JOURNAL OF NEUROSCIENCE
- Scaffolding Proteins of the Post-synaptic Density Contribute to Synaptic Plasticity by Regulating Receptor Localization and Distribution: Relevance for Neuropsychiatric Diseases
- (2012) Felice Iasevoli et al. NEUROCHEMICAL RESEARCH
- The Best Things Come in Small Packages– Vesicular Delivery of Weak Base Antipsychotics
- (2012) Andrew Morton et al. NEURON
- Use-Dependent Inhibition of Synaptic Transmission by the Secretion of Intravesicularly Accumulated Antipsychotic Drugs
- (2012) Carsten H. Tischbirek et al. NEURON
- Social isolation rearing in rats alters plasma tryptophan metabolism and is reversed by sub-chronic clozapine treatment
- (2012) Marisa Möller et al. NEUROPHARMACOLOGY
- Synaptic retinoic acid signaling and homeostatic synaptic plasticity
- (2012) Lu Chen et al. NEUROPHARMACOLOGY
- Clozapine-Induced Locomotor Suppression is Mediated by 5-HT2A Receptors in the Forebrain
- (2012) Caitlin E McOmish et al. NEUROPSYCHOPHARMACOLOGY
- Cardiovascular side-effects of antipsychotic drugs: The role of the autonomic nervous system
- (2012) Joanne Y.T. Leung et al. PHARMACOLOGY & THERAPEUTICS
- Dopamine D4 Receptor Activation Increases Hippocampal Gamma Oscillations by Enhancing Synchronization of Fast-Spiking Interneurons
- (2012) Richard Andersson et al. PLoS One
- Clozapine regulation of p90RSK and c-Fos signaling via the ErbB1-ERK pathway is distinct from olanzapine and haloperidol in mouse cortex and striatum
- (2012) Avril Pereira et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Association between CYP1A2 polymorphisms and clozapine-induced adverse reactions in patients with schizophrenia
- (2012) Marco Ferrari et al. PSYCHIATRY RESEARCH
- Effects of chronic clozapine administration on markers of arachidonic acid cascade and synaptic integrity in rat brain
- (2012) Hyung-Wook Kim et al. PSYCHOPHARMACOLOGY
- Outcome definitions and clinical predictors influence pharmacogenetic associations between HTR3A gene polymorphisms and response to clozapine in patients with schizophrenia
- (2012) A. P. Rajkumar et al. PSYCHOPHARMACOLOGY
- Second-Generation Antipsychotic Medications and Risk of Pneumonia in Schizophrenia
- (2012) Chian-Jue Kuo et al. SCHIZOPHRENIA BULLETIN
- Rapid clozapine dose titration and concomitant sodium valproate increase the risk of myocarditis with clozapine: A case–control study
- (2012) Kathlyn J. Ronaldson et al. SCHIZOPHRENIA RESEARCH
- Biased signalling and allosteric machines: new vistas and challenges for drug discovery
- (2011) Terry P Kenakin BRITISH JOURNAL OF PHARMACOLOGY
- Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs
- (2011) Miguel Fribourg et al. CELL
- A promoter variant of SHANK1 affects auditory working memory in schizophrenia patients and in subjects clinically at risk for psychosis
- (2011) Leonhard Lennertz et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- The clozapine metabolite N-desmethylclozapine displays variable activity in diverse functional assays at human dopamine D2 and serotonin 5-HT1A receptors
- (2011) Peter Heusler et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Effect of clozapine on the dimerization of serotonin 5-HT2A receptor and its genetic variant 5-HT2AH425Y with dopamine D2 receptor
- (2011) Sylwia Łukasiewicz et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Acute administration of typical and atypical antipsychotics reduces EEG gamma power, but only the preclinical compound LY379268 reduces the ketamine-induced rise in gamma power
- (2011) Nigel C. Jones et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Weight Gain and Metabolic Risks Associated with Antipsychotic Medications in Children and Adolescents
- (2011) Lawrence Maayan et al. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
- Mid-Term and Long-Term Efficacy and Effectiveness of Antipsychotic Medications for Schizophrenia
- (2011) Ira D. Glick et al. JOURNAL OF CLINICAL PSYCHIATRY
- Clozapine, but not olanzapine, disrupts conditioned avoidance response in rats by antagonizing 5-HT2A/2C receptors
- (2011) Ming Li et al. JOURNAL OF NEURAL TRANSMISSION
- Clozapine functions through the prefrontal cortex serotonin 1A receptor to heighten neuronal activity via calmodulin kinase II-NMDA receptor interactions
- (2011) Sudarshana Purkayastha et al. JOURNAL OF NEUROCHEMISTRY
- Impact of antipsychotics on cytokine production in-vitro
- (2011) Hubertus Himmerich et al. JOURNAL OF PSYCHIATRIC RESEARCH
- CYP1A2*1F Polymorphism Decreases Clinical Response to Clozapine in Patients with Schizophrenia
- (2011) Hakan Balibey et al. KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
- De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
- (2011) G Kirov et al. MOLECULAR PSYCHIATRY
- Metabolic and cardiovascular adverse effects associated with antipsychotic drugs
- (2011) Marc De Hert et al. Nature Reviews Endocrinology
- Selective Blockade of Dopamine D3 Receptors Enhances while D2 Receptor Antagonism Impairs Social Novelty Discrimination and Novel Object Recognition in Rats: A Key Role for the Prefrontal Cortex
- (2011) David JG Watson et al. NEUROPSYCHOPHARMACOLOGY
- Group II Metabotropic Glutamate Receptor Agonist Ameliorates MK801-Induced Dysfunction of NMDA Receptors via the Akt/GSK-3β Pathway in Adult Rat Prefrontal Cortex
- (2011) Dong Xi et al. NEUROPSYCHOPHARMACOLOGY
- From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment
- (2011) Bita Moghaddam et al. NEUROPSYCHOPHARMACOLOGY
- Evidence that clozapine directly interacts on the GABAB receptor
- (2011) Ying Wu et al. NEUROREPORT
- Serum brain-derived neurotrophic factor and clozapine daily dose in patients with schizophrenia: A positive correlation
- (2011) Mariana Pedrini et al. NEUROSCIENCE LETTERS
- Gene–gene interaction analyses between NMDA receptor subunit and dopamine receptor gene variants and clozapine response
- (2011) Rudi Hwang et al. PHARMACOGENOMICS
- Clinical Assessment of a Supplement of Pycnogenol® and l-arginine in Japanese Patients with Mild to Moderate Erectile Dysfunction
- (2011) Hiromitsu Aoki et al. PHYTOTHERAPY RESEARCH
- Dopamine D4 and D5 receptor gene variant effects on clozapine response in schizophrenia: Replication and exploration
- (2011) Rudi Hwang et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Are CYP1A2*1F and *1C associated with clozapine tolerability? A preliminary investigation
- (2011) Emilio Bolla et al. PSYCHIATRY RESEARCH
- The α2-adrenergic antagonist idazoxan counteracts prepulse inhibition deficits caused by amphetamine or dizocilpine in rats
- (2011) José A. Larrauri et al. PSYCHOPHARMACOLOGY
- Involvement of histamine receptors in the atypical antipsychotic profile of clozapine: a reassessment in vitro and in vivo
- (2011) Marie Humbert-Claude et al. PSYCHOPHARMACOLOGY
- Long term antipsychotic treatment does not alter metabolite concentrations in rat striatum: An in vivo magnetic resonance spectroscopy study
- (2011) Diana M. Lindquist et al. SCHIZOPHRENIA RESEARCH
- Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: An animal model
- (2011) Margaret Hahn et al. SCHIZOPHRENIA RESEARCH
- The putative functional rs1045881 marker of neurexin-1 in schizophrenia and clozapine response
- (2011) Tristram A.P. Lett et al. SCHIZOPHRENIA RESEARCH
- When can patients with potentially life-threatening adverse effects be rechallenged with clozapine? A systematic review of the published literature
- (2011) Peter Manu et al. SCHIZOPHRENIA RESEARCH
- Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance
- (2011) Ahmed Hasbi et al. Molecular Brain
- Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo
- (2011) J A Allen et al. Translational Psychiatry
- D2Receptor Genetic Variation and Clinical Response to Antipsychotic Drug Treatment: A Meta-Analysis
- (2010) Jian-Ping Zhang et al. AMERICAN JOURNAL OF PSYCHIATRY
- Dopamine D2 and 5-hydroxytryptamine 5-HT2A receptors assemble into functionally interacting heteromers
- (2010) Dasiel O. Borroto-Escuela et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hetero-dimerization of serotonin 5-HT2A and dopamine D2 receptors
- (2010) Sylwia Łukasiewicz et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The GABAB receptor as a target for antidepressant drug action
- (2010) Subroto Ghose et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effect of Clozapine on Neutrophil Kinetics in Rabbits
- (2010) Suzanne Iverson et al. CHEMICAL RESEARCH IN TOXICOLOGY
- All Roads to Schizophrenia Lead to Dopamine Supersensitivity and Elevated Dopamine D2High Receptors
- (2010) Philip Seeman CNS Neuroscience & Therapeutics
- The α2 adrenergic receptor antagonist idazoxan, but not the serotonin-2A receptor antagonist M100907, partially attenuated reward deficits associated with nicotine, but not amphetamine, withdrawal in rats
- (2010) Svetlana Semenova et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Schizophrenia severity and clozapine treatment outcome association with oxytocinergic genes
- (2010) Renan P. Souza et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- The Dopamine D1-D2 Receptor Heteromer Localizes in Dynorphin/Enkephalin Neurons
- (2010) Melissa L. Perreault et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diagnostic Characteristics of Clozapine-Induced Myocarditis Identified by an Analysis of 38 Cases and 47 Controls
- (2010) Kathlyn J. Ronaldson et al. JOURNAL OF CLINICAL PSYCHIATRY
- Candidate Gene Analysis Identifies a Polymorphism inHLA-DQB1Associated With Clozapine-Induced Agranulocytosis
- (2010) Maria C. Athanasiou et al. JOURNAL OF CLINICAL PSYCHIATRY
- Genetic association of the GDNF alpha-receptor genes with schizophrenia and clozapine response
- (2010) Renan P. Souza et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Influence of serotonin transporter gene polymorphisms on clozapine response in Brazilian schizophrenics
- (2010) Fabiana B. Kohlrausch et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Pattern of acute induction of Homer1a gene is preserved after chronic treatment with first- and second-generation antipsychotics: effect of short-term drug discontinuation and comparison with Homer1a-interacting genes
- (2010) Felice Iasevoli et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Clozapine does not require 5-HT1A receptors to block the locomotor hyperactivity induced by MK-801
- (2010) María Cecilia Scorza et al. NEUROPHARMACOLOGY
- In Vivo Binding of Antipsychotics to D3 and D2 Receptors: A PET Study in Baboons with [11C]-(+)-PHNO
- (2010) Ragy R Girgis et al. NEUROPSYCHOPHARMACOLOGY
- Antipsychotics Associated with the Development of Type 2 Diabetes in Antipsychotic-Naïve Schizophrenia Patients
- (2010) Jimmi Nielsen et al. NEUROPSYCHOPHARMACOLOGY
- Influence of serotonin 3A and 3B receptor genes on clozapine treatment response in schizophrenia
- (2010) Renan P. Souza et al. Pharmacogenetics and Genomics
- Homeostatic regulation of glutamatergic transmission by dopamine D4 receptors
- (2010) E. Y. Yuen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct involvement of -1 receptors in the dopamine D1 receptor-mediated effects of cocaine
- (2010) G. Navarro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharacogenetic effects of dopamine transporter gene polymorphisms on response to chlorpromazine and clozapine and on extrapyramidal syndrome in schizophrenia
- (2010) Mingqing Xu et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The acute and chronic effects of combined antipsychotic–mood stabilizing treatment on the expression of cortical and striatal postsynaptic density genes
- (2010) Carmine Tomasetti et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Effects of aripiprazole and haloperidol on progression to schizophrenia-like behavioural abnormalities and apoptosis in rodents
- (2010) Tomohiro Abekawa et al. SCHIZOPHRENIA RESEARCH
- Association between HLA-A1 allele and schizophrenia gene(s) in patients refractory to conventional neuroleptics but responsive to clozapine medication
- (2010) L. Lahdelma et al. TISSUE ANTIGENS
- Novel insights into the function of β-cell M3 muscarinic acetylcholine receptors: therapeutic implications
- (2010) Inigo Ruiz de Azua et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The effects of the second generation antipsychotics and a typical neuroleptic on collagen-induced platelet aggregationin vitro
- (2010) Anna Dietrich-Muszalska et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- Which comes first: atypical antipsychotic treatment or cardiometabolic risk?
- (2009) S. M. Stahl et al. ACTA PSYCHIATRICA SCANDINAVICA
- Voltage-gated sodium channel modulation by σ-receptors in cardiac myocytes and heterologous systems
- (2009) Molly Johannessen et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Clozapine protects PC-12 cells from death due to oxidative stress induced by hydrogen peroxide via a cell-type specific mechanism involving inhibition of extracellular signal-regulated kinase phosphorylation
- (2009) Brian C. Magliaro et al. BRAIN RESEARCH
- Clozapine inhibits strychnine-sensitive glycine receptors in rat hippocampal neurons
- (2009) Yong Liu et al. BRAIN RESEARCH
- Antipsychotic and antidepressant co-treatment: Effects on transcripts of inducible postsynaptic density genes possibly implicated in behavioural disorders
- (2009) Carmela Dell’Aversano et al. BRAIN RESEARCH BULLETIN
- Bexarotene as Add-On to Antipsychotic Treatment in Schizophrenia Patients
- (2009) Vladimir Lerner et al. CLINICAL NEUROPHARMACOLOGY
- Clozapine, GABAB, and the Treatment of Resistant Schizophrenia
- (2009) Z J Daskalakis et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Dopamine D2–D3 receptor heteromers: pharmacological properties and therapeutic significance
- (2009) Roberto Maggio et al. CURRENT OPINION IN PHARMACOLOGY
- Agonist activity of N-desmethylclozapine at δ-opioid receptors of human frontal cortex
- (2009) Maria C. Olianas et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- A review of smoking cessation: potentially risky effects on prescribed medications
- (2009) Susan D Schaffer et al. JOURNAL OF CLINICAL NURSING
- Life-Threatening Clozapine-Induced Gastrointestinal Hypomotility
- (2009) Susanna E. Palmer et al. JOURNAL OF CLINICAL PSYCHIATRY
- Association Between HTR2C and HTR2A Polymorphisms and Metabolic Abnormalities in Patients Treated With Olanzapine or Clozapine
- (2009) Arzu Gunes et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Differential Effects of M1 and 5-Hydroxytryptamine1A Receptors on Atypical Antipsychotic Drug-Induced Dopamine Efflux in the Medial Prefrontal Cortex
- (2009) Z. Li et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Analyzing the Effects of Psychotropic Drugs on Metabolite Profiles in Rat Brain Using1H NMR Spectroscopy
- (2009) Gerard A. McLoughlin et al. JOURNAL OF PROTEOME RESEARCH
- MAP'ing CNS Development and Cognition: An ERKsome Process
- (2009) Ivy S. Samuels et al. NEURON
- The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation
- (2009) Lingjun Zuo et al. Pharmacogenetics and Genomics
- Effect of dopamine D3 receptor gene polymorphisms and clozapine treatment response: exploratory analysis of nine polymorphisms and meta-analysis of the Ser9Gly variant
- (2009) R Hwang et al. PHARMACOGENOMICS JOURNAL
- Identification of a Domain which Affects Kinetics and Antagonistic Potency of Clozapine at 5-HT3 Receptors
- (2009) Gerhard Rammes et al. PLoS One
- Decreased serum BDNF levels in chronic institutionalized schizophrenia on long-term treatment with typical and atypical antipsychotics
- (2009) Mei Hong Xiu et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The role of histaminergic H1 and H3 receptors in food intake: A mechanism for atypical antipsychotic-induced weight gain?
- (2009) Chao Deng et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The effect of clozapine on regional cerebral blood flow and brain metabolite ratios in schizophrenia: Relationship with treatment response
- (2009) Aygun Ertugrul et al. PSYCHIATRY RESEARCH-NEUROIMAGING
- Modulation of prepulse inhibition through both M1 and M4 muscarinic receptors in mice
- (2009) Morgane Thomsen et al. PSYCHOPHARMACOLOGY
- The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway
- (2009) O. D. Howes et al. SCHIZOPHRENIA BULLETIN
- Upregulation of NRG-1 and VAMP-1 in human brain aggregates exposed to clozapine
- (2009) Gursharan Chana et al. SCHIZOPHRENIA RESEARCH
- Effects of clozapine and olanzapine on cortical thickness in childhood-onset schizophrenia
- (2009) Anand Mattai et al. SCHIZOPHRENIA RESEARCH
- Lack of association between DRD3 gene polymorphism and response to clozapine in Turkish schizoprenia patients
- (2008) I. Omer Barlas et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Does stimulation of 5-HT1A receptors improve cognition in schizophrenia?
- (2008) Herbert Y. Meltzer et al. BEHAVIOURAL BRAIN RESEARCH
- Common behavioral influences of the ErbB1 ligands transforming growth factor alpha and epiregulin administered to mouse neonates
- (2008) Noriko Tsuda et al. BRAIN & DEVELOPMENT
- Characterization of clozapine-induced changes in synaptic plasticity in the hippocampal–mPFC pathway of anesthetized rats
- (2008) Machiko Matsumoto et al. BRAIN RESEARCH
- Clozapine-induced myocarditis: Role of catecholamines in a murine model
- (2008) Ju-Feng Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The role of D1–D2 receptor hetero-dimerization in the mechanism of action of clozapine
- (2008) Agata Faron-Górecka et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Decreased M1 muscarinic receptor density in rat amphetamine model of schizophrenia is normalized by clozapine, but not haloperidol
- (2008) Adi Malkoff et al. JOURNAL OF NEURAL TRANSMISSION
- Influence of positive allosteric modulators on GABABreceptor coupling in rat brain: a scintillation proximity assay characterisation of G protein subtypes
- (2008) Clotilde Mannoury la Cour et al. JOURNAL OF NEUROCHEMISTRY
- Haloperidol and Clozapine Differentially Affect the Expression of Arrestins, Receptor Kinases, and Extracellular Signal-Regulated Kinase Activation
- (2008) M. R. Ahmed et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Anticholinergic Activity of 107 Medications Commonly Used by Older Adults
- (2008) Marci L. Chew et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis
- (2008) Stefan Leucht et al. LANCET
- Clozapine interacts with the glycine site of the NMDA receptor: Electrophysiological studies of dopamine neurons in the rat ventral tegmental area
- (2008) Lilly Schwieler et al. LIFE SCIENCES
- Identification of a serotonin/glutamate receptor complex implicated in psychosis
- (2008) Javier González-Maeso et al. NATURE
- G-protein gene 825C>T polymorphism is associated with response to clozapine in Brazilian schizophrenics
- (2008) Fabiana B Kohlrausch et al. PHARMACOGENOMICS
- Clozapine may partially compensate for task-related brain perfusion abnormalities in risperidone-resistant schizophrenia patients
- (2008) V. Molina et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Atypical antipsychotics suppress production of proinflammatory cytokines and up-regulate interleukin-10 in lipopolysaccharide-treated mice
- (2008) Haruhiko Sugino et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression
- (2008) Mei Han et al. PSYCHONEUROENDOCRINOLOGY
- Effects of clozapine and olanzapine on cytokine systems are closely linked to weight gain and drug-induced fever
- (2008) Michael Kluge et al. PSYCHONEUROENDOCRINOLOGY
- Orthostatic hypotensive effect of antipsychotic drugs in Wistar rats by in vivo and in vitro studies of α1-adrenoceptor function
- (2008) Z. Nourian et al. PSYCHOPHARMACOLOGY
- Atypical Antipsychotics: CATIE Study, Drug-Induced Movement Disorder and Resulting Iatrogenic Psychiatric-Like Symptoms, Supersensitivity Rebound Psychosis and Withdrawal Discontinuation Syndromes
- (2008) Guy Chouinard et al. PSYCHOTHERAPY AND PSYCHOSOMATICS
- Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia
- (2008) T. Walsh et al. SCIENCE
- Pharmacological characterization and CNS effects of a novel highly selective α2C-adrenoceptor antagonist JP-1302
- (2007) J Sallinen et al. BRITISH JOURNAL OF PHARMACOLOGY
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