The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans

Dopamine, the antipsychotic molecule: A perspective on mechanisms underlying antipsychotic response variability

(2018) Davide Amato et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment

(2018) Diego Scheggia et al.   Nature Communications

Evidence of an epistatic effect between Dysbindin-1 and Neuritin-1 genes on the risk for schizophrenia spectrum disorders

(2017) C. Prats et al.   EUROPEAN PSYCHIATRY

D3 Receptors Regulate Excitability in a Unique Class of Prefrontal Pyramidal Cells

(2017) Rebecca L. Clarkson et al.   JOURNAL OF NEUROSCIENCE

Remote memories are enhanced by COMT activity through dysregulation of the endocannabinoid system in the prefrontal cortex

(2017) D Scheggia et al.   MOLECULAR PSYCHIATRY

Dopamine transporter (DAT) genetic hypofunction in mice produces alterations consistent with ADHD but not schizophrenia or bipolar disorder

(2017) M. Mereu et al.   NEUROPHARMACOLOGY

Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D3 Receptor Blockade

(2017) Sebastiano Alfio Torrisi et al.   Frontiers in Pharmacology

The dopamine D3 receptor, a quarter century later

(2016) Pierre Sokoloff et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dysbindin-1 modifies signaling and cellular localization of recombinant, human D3 and D2 receptors

(2016) Nathalie Schmieg et al.   JOURNAL OF NEUROCHEMISTRY

Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression

(2016) Anthony A. Grace   NATURE REVIEWS NEUROSCIENCE

Current drug treatments targeting dopamine D3 receptor

(2016) Gian Marco Leggio et al.   PHARMACOLOGY & THERAPEUTICS

Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia

(2016) Francesca Managò et al.   Cell Reports

Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases

(2016) Samuele Maramai et al.   Frontiers in Neuroscience

Sex-dichotomous effects of functional COMT genetic variations on cognitive functions disappear after menopause in both health and schizophrenia

(2015) Francesco Papaleo et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Pharmacological targeting of dopamine D3 receptors: Possible clinical applications of selective drugs

(2015) Emilio Merlo Pich et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The mRNA Expression Status of Dopamine Receptor D2, Dopamine Receptor D3 and DARPP-32 in T Lymphocytes of Patients with Early Psychosis

(2015) Yin Cui et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

COMT Genetic Reduction Produces Sexually Divergent Effects on Cortical Anatomy and Working Memory in Mice and Humans

(2014) Sara Sannino et al.   CEREBRAL CORTEX

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Blonanserin Ameliorates Phencyclidine-Induced Visual-Recognition Memory Deficits: the Complex Mechanism of Blonanserin Action Involving D3-5-HT2A and D1-NMDA Receptors in the mPFC

(2014) Hirotake Hida et al.   NEUROPSYCHOPHARMACOLOGY

The Ultimate Intra-/Extra-Dimensional Attentional Set-Shifting Task for Mice

(2013) Diego Scheggia et al.   BIOLOGICAL PSYCHIATRY

The potential role of dopamine D3 receptor neurotransmission in cognition

(2013) Shinichiro Nakajima et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Epistatic interaction between COMT and DTNBP1 modulates prefrontal function in mice and in humans

(2013) F Papaleo et al.   MOLECULAR PSYCHIATRY

Chronic and Acute Intranasal Oxytocin Produce Divergent Social Effects in Mice

(2013) Huiping Huang et al.   NEUROPSYCHOPHARMACOLOGY

Psychiatric Drugs Bind to Classical Targets Within Early Exocytotic Pathways: Therapeutic Effects

(2012) Henry A. Lester et al.   BIOLOGICAL PSYCHIATRY

Synaptic Activity Unmasks Dopamine D2 Receptor Modulation of a Specific Class of Layer V Pyramidal Neurons in Prefrontal Cortex

(2012) S. Gee et al.   JOURNAL OF NEUROSCIENCE

Use-Dependent Inhibition of Synaptic Transmission by the Secretion of Intravesicularly Accumulated Antipsychotic Drugs

(2012) Carsten H. Tischbirek et al.   NEURON

Update: Studies of prepulse inhibition of startle, with particular relevance to the pathophysiology or treatment of Tourette Syndrome

(2012) Neal R. Swerdlow   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Hypothesis review: are clathrin-mediated endocytosis and clathrin-dependent membrane and protein trafficking core pathophysiological processes in schizophrenia and bipolar disorder?

(2011) K O Schubert et al.   MOLECULAR PSYCHIATRY

Mouse models of genetic effects on cognition: Relevance to schizophrenia

(2011) Francesco Papaleo et al.   NEUROPHARMACOLOGY

Dysbindin and Schizophrenia: It's Dopamine and Glutamate All Over Again

(2010) Francesco Papaleo et al.   BIOLOGICAL PSYCHIATRY

Dopamine D3Receptors Are Down-regulated following Heterologous Endocytosis by a Specific Interaction with G Protein-coupled Receptor-associated Sorting Protein-1

(2010) Dawn Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Projection-Specific Neuromodulation of Medial Prefrontal Cortex Neurons

(2010) N. C. Dembrow et al.   JOURNAL OF NEUROSCIENCE

Dysbindin-1 modulates prefrontal cortical activity and schizophrenia-like behaviors via dopamine/D2 pathways

(2010) F Papaleo et al.   MOLECULAR PSYCHIATRY

Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects

(2009) Kwang H Choi et al.   BMC Psychiatry

Role of dysbindin in dopamine receptor trafficking and cortical GABA function

(2009) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling the Positive Symptoms of Schizophrenia in Genetically Modified Mice: Pharmacology and Methodology Aspects

(2009) M. van den Buuse   SCHIZOPHRENIA BULLETIN

Set-Shifting Ability and Schizophrenia: A Marker of Clinical Illness or an Intermediate Phenotype?

(2008) Alan E. Ceaser et al.   BIOLOGICAL PSYCHIATRY

On the historical and conceptual background of the Wisconsin Card Sorting Test

(2008) Paul Eling et al.   BRAIN AND COGNITION

Genetic Dissection of the Role of Catechol-O-Methyltransferase in Cognition and Stress Reactivity in Mice

(2008) F. Papaleo et al.   JOURNAL OF NEUROSCIENCE

Habituation and sensitization of acoustic startle: Opposite influences of dopamine D1 and D2-family receptors

(2008) Adam L. Halberstadt et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Antipsychotics differ in their ability to internalise human dopamine D2S and human serotonin 5-HT1A receptors in HEK293 cells

(2007) Peter Heusler et al.   EUROPEAN JOURNAL OF PHARMACOLOGY