Luminescent and Photofunctional Transition Metal Complexes: From Molecular Design to Diagnostic and Therapeutic Applications

Phosphorogenic Iridium(III) bis ‐Tetrazine Complexes for Bioorthogonal Peptide Stapling, Bioimaging, Photocytotoxic Applications, and the Construction of Nanosized Hydrogels

(2022) Alex Man‐Hei Yip et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemiluminescent 1,2‐Dioxetane Iridium Complexes for Near‐Infrared Oxygen Sensing

(2022) Husain N. Kagalwala et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-based anticancer agents as immunogenic cell death inducers: the past, present, and future

(2022) Sajal Sen et al.   CHEMICAL SOCIETY REVIEWS

Phototherapeutic anticancer strategies with first-row transition metal complexes: a critical review

(2022) Lisa Gourdon et al.   CHEMICAL SOCIETY REVIEWS

Photodecaging of a Mitochondria-Localized Iridium(III) Endoperoxide Complex for Two-Photon Photoactivated Therapy under Hypoxia

(2022) Shi Kuang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Photoreactive Iron(II) Complex Luminophore

(2022) Wolfgang Leis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NADH-depletion triggered energy shutting with cyclometalated iridium (III) complex enabled bimodal Luminescence-SERS sensing and photodynamic therapy

(2022) Shanmughan Shamjith et al.   BIOSENSORS & BIOELECTRONICS

Cobalt(III) Complexes for Light-Activated Delivery of Acetylacetonate-BODIPY, Cellular Imaging, and Photodynamic Therapy

(2022) Avishek Jana et al.   INORGANIC CHEMISTRY

Nonaromatic Organonickel(II) Phototheranostics

(2022) Yuhang Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intraligand Excited States Turn a Ruthenium Oligothiophene Complex into a Light-Triggered Ubertoxin with Anticancer Effects in Extreme Hypoxia

(2022) John A. Roque III et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construct Sturdy Packing of Self‐Assembling Iridium Complex via Endocytic Trafficking for Long‐Term Lysosome Tracking

(2021) Chengzhi Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In‐vitro and In‐vivo Photo‐catalytic Cancer Therapy with Bio‐compatible Iridium(III) Photo‐catalysts

(2021) Huaiyi Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Reactions Utilizing Nitrones as Versatile Dipoles in Cycloaddition Reactions

(2021) Didier A. Bilodeau et al.   CHEMICAL REVIEWS

Microsecond Photoluminescence and Photoreactivity of a Metal-Centered Excited State in a Hexacarbene–Co(III) Complex

(2021) Simon Kaufhold et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Photorobust Mo(0) Complex Mimicking [Os(2,2′-bipyridine)3]2+ and Its Application in Red-to-Blue Upconversion

(2021) Jakob B. Bilger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Analysing the mechanism of mitochondrial oxidation-induced cell death using a multifunctional iridium(III) photosensitiser

(2021) Chaiheon Lee et al.   Nature Communications

Ferroptosis Photoinduced by New Cyclometalated Iridium(III) Complexes and Its Synergism with Apoptosis in Tumor Cell Inhibition

(2021) Hao Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light‐Driven Cascade Mitochondria‐to‐Nucleus Photosensitization in Cancer Cell Ablation

(2021) Kang‐Nan Wang et al.   Advanced Science

Aggregation and Supramolecular Self-Assembly of Low-Energy Red Luminescent Alkynylplatinum(II) Complexes for RNA Detection, Nucleolus Imaging, and RNA Synthesis Inhibitor Screening

(2021) Angela Sin-Yee Law et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Far‐Red/NIR‐Absorbing Neutral Ir(III) Complex Micelles for Potent Photodynamic/Photothermal Therapy

(2021) Bingqing Liu et al.   ADVANCED MATERIALS

A Near‐Infrared‐II Emissive Chromium(III) Complex

(2021) Narayan Sinha et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Utilization of Rhenium(I) Polypyridine Complexes Featuring a Dinitrophenylsulfonamide Moiety as Biothiol‐Selective Phosphorogenic Bioimaging Reagents and Photocytotoxic Agents

(2021) Guang‐Xi Xu et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Induction and Monitoring of DNA Phase Separation in Living Cells by a Light-Switching Ruthenium Complex

(2021) Wen-Jin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyrene-Decoration of a Chromium(0) Tris(diisocyanide) Enhances Excited State Delocalization: A Strategy to Improve the Photoluminescence of 3d6 Metal Complexes

(2021) Christina Wegeberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strongly Red-Emissive Molecular Ruby [Cr(bpmp)2]3+ Surpasses [Ru(bpy)3]2+

(2021) Florian Reichenauer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photosensitive Ru(II) Complexes as Inhibitors of the Major Human Drug Metabolizing Enzyme CYP3A4

(2021) Nicholas Toupin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Manganese(i) complexes with metal-to-ligand charge transfer luminescence and photoreactivity

(2021) Patrick Herr et al.   Nature Chemistry

Multifunctional AIE iridium (III) photosensitizer nanoparticles for two-photon-activated imaging and mitochondria targeting photodynamic therapy

(2021) Xuzi Cai et al.   JOURNAL OF NANOBIOTECHNOLOGY

Functionalizing Collagen with Vessel‐Penetrating Two‐Photon Phosphorescence Probes: A New In Vivo Strategy to Map Oxygen Concentration in Tumor Microenvironment and Tissue Ischemia

(2021) Cheng‐Ham Wu et al.   Advanced Science

A Carbonic Anhydrase IX (CAIX)‐Anchored Rhenium(I) Photosensitizer Evokes Pyroptosis for Enhanced Anti‐Tumor Immunity

(2021) Xuxian Su et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Anticancer Agent with Inexplicable Potency in Extreme Hypoxia: Characterizing a Light-Triggered Ruthenium Ubertoxin

(2021) Houston D. Cole et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Dinuclear Osmium(II) Complex Near-Infrared Nanoscopy Probe for Nuclear DNA

(2021) Fabian Dröge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Design of Bioorthogonal Probes and Imaging Reagents Derived from Photofunctional Transition Metal Complexes

(2020) Kenneth Kam-Wing Lo   ACCOUNTS OF CHEMICAL RESEARCH

A Multiaction and Multitarget Ru(II)-Pt(IV) Conjugate Combining Cancer Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers

(2020) Johannes Karges et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Supramolecular Phthalocyanine Assemblies for Improved Photoacoustic Imaging and Photothermal Therapy

(2020) Xingshu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitochondrial-DNA-Targeted IrIII -Containing Metallohelices with Tunable Photodynamic Therapy Efficacy in Cancer Cells

(2020) Xuezhao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two-Coordinate Copper(I)/NHC Complexes: Dual Emission Properties and Ultralong Room-Temperature Phosphorescence

(2020) Jiayi Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Dinuclear Ruthenium(II) Complex Excited by Near-Infrared Light through Two-Photon Absorption Induces Phototoxicity Deep within Hypoxic Regions of Melanoma Cancer Spheroids

(2020) Ahtasham Raza et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward the Design of Phosphorescent Emitters of Cyclometalated Earth-Abundant Nickel(II) and Their Supramolecular Study

(2020) Yip-Sang Wong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Vanadium(III) Complex with Blue and NIR-II Spin-Flip Luminescence in Solution

(2020) Matthias Dorn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cyclic (Amino)(aryl)carbenes Enter the Field of Chromophore Ligands: Expanded π System Leads to Unusually Deep Red Emitting CuI Compounds

(2020) Markus Gernert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rationally Designed Long-Wavelength Absorbing Ru(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy

(2020) Johannes Karges et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Delayed fluorescence from a zirconium(iv) photosensitizer with ligand-to-metal charge-transfer excited states

(2020) Yu Zhang et al.   Nature Chemistry

“Two Birds with One Stone” Ruthenium(II) Complex Probe for Biothiols Discrimination and Detection In Vitro and In Vivo

(2020) Chaolong Liu et al.   Advanced Science

A Mitochondrion‐Localized Two‐Photon Photosensitizer Generating Carbon Radicals against Hypoxic Tumors

(2020) Hui Chao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiple‐Color Platinum Complex with Super‐Large Stokes Shift for Super‐Resolution Imaging of Autolysosome Escape

(2020) Liu-Yi Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electronic structure and photophysics of a supermolecular iron complex having a long MLCT-state lifetime and panchromatic absorption

(2020) Ting Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy

(2020) Johannes Karges et al.   Nature Communications

Fighting against Drug‐Resistant Tumors using a Dual‐Responsive Pt(IV)/Ru(II) Bimetallic Polymer

(2020) Xiaolong Zeng et al.   ADVANCED MATERIALS

A Cyclometalated Iridium (III) Complex as a Microtubule Probe for Correlative Super‐Resolution Fluorescence and Electron Microscopy

(2020) Xiaohe Tian et al.   ADVANCED MATERIALS

Ni(II) curcumin complexes for cellular imaging and photo-triggered in vitro anticancer activity

(2020) Atrayee Banaspati et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Manganese(II) Texaphyrin: A Paramagnetic Photoacoustic Contrast Agent Activated by Near-IR Light

(2020) Yaguang Ren et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Iridium (III) Complex Bearing a Donor–Acceptor–Donor Type Ligand for NIR‐Triggered Dual Phototherapy

(2020) Jian Zhao et al.   ADVANCED FUNCTIONAL MATERIALS

Supramolecular Assembly of An Organoplatinum(II) Complex with Ratiometric Dual Emission for Two‐Photon Bioimaging

(2020) Cheng Ouyang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Precise Tumor Photothermal Therapy Guided and Monitored by Magnetic Resonance/Photoacoustic Imaging using A Safe and pH‐Responsive Fe(III) Complex

(2020) Guohai Liang et al.   Advanced Healthcare Materials

AIE Multinuclear Ir(III) Complexes for Biocompatible Organic Nanoparticles with Highly Enhanced Photodynamic Performance

(2019) Liping Zhang et al.   Advanced Science

Eliminating nonradiative decay in Cu(I) emitters: >99% quantum efficiency and microsecond lifetime

(2019) Rasha Hamze et al.   SCIENCE

A “Dual-key-and-lock” Ruthenium Complex Probe for Lysosomal Formaldehyde in Cancer Cells and Tumors

(2019) Liu Chaolong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Photo- and Electroluminescence from Two-Coordinate Cu(I) Complexes Featuring Nonconventional N-Heterocyclic Carbenes

(2019) Shuyang Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards novel photodynamic anticancer agents generating superoxide anion radicals: A cyclometalated Ir(III) complex conjugated to a far-red emitting coumarin

(2019) Vojtech Novohradsky et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Strongly Luminescent Tungsten Emitters with Emission Quantum Yields up to 84%: TADF and High-Efficiency Molecular Tungsten OLEDs

(2019) Kaai-Tung Chan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New designs for phototherapeutic transition metal complexes

(2019) Peter J. Sadler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Molecular Ruby [Cr(dqp)2]3+ with Long-Lived Circularly Polarized Luminescence

(2019) Juan-Ramón Jiménez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Long-Lived, Strongly Emissive, and Highly Reducing Excited States in Mo(0) Complexes with Chelating Isocyanides

(2019) Patrick Herr et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted photoredox catalysis in cancer cells

(2019) Huaiyi Huang et al.   Nature Chemistry

Luminescence and Light-Driven Energy and Electron Transfer from an Exceptionally Long-Lived Excited State of a Non-Innocent Chromium(III) Complex

(2019) Steffen Treiling et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photo-Uncaging of a Microtubule-Targeted Rigidin Analogue in Hypoxic Cancer Cells and in a Xenograft Mouse Model

(2019) Vincent H. S. van Rixel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring the Phototoxicity of Hypoxic Active Iridium(III)-Based Sensitizers in 3D Tumor Spheroids

(2019) Robin Bevernaegie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Making the Right Link to Theranostics: The Photophysical and Biological Properties of Dinuclear RuII–ReI dppz Complexes Depend on Their Tether

(2019) Hiwa K. Saeed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioorthogonal “Labeling after Recognition” Affording an FRET-Based Luminescent Probe for Detecting and Imaging Caspase-3 via Photoluminescence Lifetime Imaging

(2019) Qi Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Monitoring and Visualization of Hydrogen Sulfide In Vivo Using a Luminescent Probe Based on a Ruthenium(II) Complex

(2018) Zhongbo Du et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Blue-Emissive Cobalt(III) Complexes and Their Use in the Photocatalytic Trifluoromethylation of Polycyclic Aromatic Hydrocarbons

(2018) Amlan K. Pal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deuterated Molecular Ruby with Record Luminescence Quantum Yield

(2018) Cui Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Selective Mitochondrial Targeting by a Ruthenium(II) Peptide Conjugate: Imaging and Photoinduced Damage of Mitochondrial DNA

(2018) Tia E. Keyes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Long-Lived Emissive Probes for Time-Resolved Photoluminescence Bioimaging and Biosensing

(2018) Kenneth Yin Zhang et al.   CHEMICAL REVIEWS

Transition metal complexes as photosensitisers in one- and two-photon photodynamic therapy

(2018) Luke K. McKenzie et al.   COORDINATION CHEMISTRY REVIEWS

Mitochondria-localizing BODIPY–copper(ii) conjugates for cellular imaging and photo-activated cytotoxicity forming singlet oxygen

(2018) Arnab Bhattacharyya et al.   DALTON TRANSACTIONS

Fluorescent antitumor titanium(iv) salen complexes for cell imaging

(2018) Avia Tzubery et al.   DALTON TRANSACTIONS

A Luminescent Manganese PhotoCORM for CO Delivery to Cellular Targets under the Control of Visible Light

(2018) Jorge Jimenez et al.   INORGANIC CHEMISTRY

Targeting Photoinduced DNA Destruction by Ru(II) Tetraazaphenanthrene in Live Cells by Signal Peptide

(2018) Christopher S. Burke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Zirconium Photosensitizer with a Long-Lived Excited State: Mechanistic Insight into Photoinduced Single-Electron Transfer

(2018) Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual-Phosphorescent Iridium(III) Complexes Extending Oxygen Sensing from Hypoxia to Hyperoxia

(2018) Kenneth Yin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New application of phthalocyanine molecules: from photodynamic therapy to photothermal therapy by means of structural regulation rather than formation of aggregates

(2018) Xingshu Li et al.   Chemical Science

Red-Light-Controlled Release of Drug-Ru Complex Conjugates from Metallopolymer Micelles for Phototherapy in Hypoxic Tumor Environments

(2018) Wen Sun et al.   ADVANCED FUNCTIONAL MATERIALS

Rational Design of Phosphorescent Iridium(III) Complexes for Selective Glutathione Sensing and Amplified Photodynamic Therapy

(2018) Tianci Huang et al.   CHEMBIOCHEM

Visualizing and discovering cellular structures with super-resolution microscopy

(2018) Yaron M. Sigal et al.   SCIENCE

Super-Resolution Tracking of Mitochondrial Dynamics with An Iridium(III) Luminophore

(2018) Qixin Chen et al.   Small

Nucleus-Targeted Organoiridium-Albumin Conjugate for Photodynamic Cancer Therapy

(2018) Pingyu Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433

(2018) Susan Monro et al.   CHEMICAL REVIEWS

Catch and Release Photosensitizers: Combining Dual-Action Ruthenium Complexes with Protease Inactivation for Targeting Invasive Cancers

(2018) Karan Arora et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoactive Complexes with Earth-Abundant Metals

(2018) Oliver S. Wenger   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Luminescence and reactivity of a charge-transfer excited iron complex with nanosecond lifetime

(2018) Kasper Skov Kjær et al.   SCIENCE

Dual function luminescent transition metal complexes for cancer theranostics: The combination of diagnosis and therapy

(2018) Chung-Nga Ko et al.   COORDINATION CHEMISTRY REVIEWS

Oxygen imaging of living cells and tissues using luminescent molecular probes

(2017) Toshitada Yoshihara et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS

Multimodal Super-resolution Optical Microscopy Using a Transition-Metal-Based Probe Provides Unprecedented Capabilities for Imaging Both Nuclear Chromatin and Mitochondria

(2017) Sreejesh Sreedharan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mitochondria Targeted Protein-Ruthenium Photosensitizer for Efficient Photodynamic Applications

(2017) Sabyasachi Chakrabortty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Tris(diisocyanide)chromium(0) Complex Is a Luminescent Analog of Fe(2,2′-Bipyridine)32+

(2017) Laura A. Büldt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A low-spin Fe(iii) complex with 100-ps ligand-to-metal charge transfer photoluminescence

(2017) Pavel Chábera et al.   NATURE

Using highly emissive and environmentally sensitive o-carborane-functionalized metallophosphors to monitor mitochondrial polarity

(2017) Xiang Li et al.   Chemical Science

Photothermal-triggered release of singlet oxygen from an endoperoxide-containing polymeric carrier for killing cancer cells

(2017) Wen Lv et al.   Materials Horizons

Successively activatable ultrasensitive probe for imaging tumour acidity and hypoxia

(2017) Xianchuang Zheng et al.   Nature Biomedical Engineering

Phosphorescent Polymeric Thermometers for In Vitro and In Vivo Temperature Sensing with Minimized Background Interference

(2016) Zejing Chen et al.   ADVANCED FUNCTIONAL MATERIALS

An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo

(2016) Wen Sun et al.   ADVANCED MATERIALS

Luminescent Tungsten(VI) Complexes: Photophysics and Applicability to Organic Light-Emitting Diodes and Photocatalysis

(2016) Kwan-Ting Yeung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Molybdenum(0) Isocyanide Analogue of Ru(2,2′-Bipyridine)32+: A Strong Reductant for Photoredox Catalysis

(2016) Laura A. Büldt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Mitochondria-Targeted Photosensitizer Showing Improved Photodynamic Therapy Effects Under Hypoxia

(2016) Wen Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Installing an additional emission quenching pathway in the design of iridium(III)-based phosphorogenic biomaterials for bioorthogonal labelling and imaging

(2016) Steve Po-Yam Li et al.   BIOMATERIALS

Photoactivatable cytotoxic agents derived from mitochondria-targeting luminescent iridium(iii) poly(ethylene glycol) complexes modified with a nitrobenzyl linkage

(2016) Karson Ka-Shun Tso et al.   CHEMICAL COMMUNICATIONS

New insights into the pretargeting approach to image and treat tumours

(2016) Malay Patra et al.   CHEMICAL SOCIETY REVIEWS

Structural Manipulation of Ruthenium(II) Polypyridine Nitrone Complexes to Generate Phosphorogenic Bioorthogonal Reagents for Selective Cellular Labeling

(2016) Tommy Siu-Ming Tang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Two-photon luminescent metal complexes for bioimaging and cancer phototherapy

(2016) Yu Chen et al.   COORDINATION CHEMISTRY REVIEWS

Synthesis and Electrochemical, Photophysical, and Self-Assembly Studies on Water-Soluble pH-Responsive Alkynylplatinum(II) Terpyridine Complexes

(2016) Clive Yik-Sham Chung et al.   INORGANIC CHEMISTRY

A Luminescent Zirconium(IV) Complex as a Molecular Photosensitizer for Visible Light Photoredox Catalysis

(2016) Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endoplasmic Reticulum-Localized Iridium(III) Complexes as Efficient Photodynamic Therapy Agents via Protein Modifications

(2016) Jung Seung Nam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal Reaction

(2016) Li Li et al.   MOLECULES

Precision targeted ruthenium(ii) luminophores; highly effective probes for cell imaging by stimulated emission depletion (STED) microscopy

(2016) Aisling Byrne et al.   Chemical Science

Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA

(2016) Sin Ki Fung et al.   Nature Communications

Luminescent Rhenium(I) and Iridium(III) Polypyridine Complexes as Biological Probes, Imaging Reagents, and Photocytotoxic Agents

(2015) Kenneth Kam-Wing Lo   ACCOUNTS OF CHEMICAL RESEARCH

Highly Charged Ruthenium(II) Polypyridyl Complexes as Lysosome-Localized Photosensitizers for Two-Photon Photodynamic Therapy

(2015) Huaiyi Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conferring Phosphorogenic Properties on Iridium(III)-Based Bioorthogonal Probes through Modification with a Nitrone Unit

(2015) Lawrence Cho-Cheung Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

[Cr(ddpd)2]3+: A Molecular, Water-Soluble, Highly NIR-Emissive Ruby Analogue

(2015) Sven Otto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tracking Cancer Metastasis In Vivo by Using an Iridium-Based Hypoxia-Activated Optical Oxygen Nanosensor

(2015) Xianchuang Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modification of 1,2,4,5-tetrazine with cationic rhenium(i) polypyridine units to afford phosphorogenic bioorthogonal probes with enhanced reaction kinetics

(2015) Alex Wing-Tat Choi et al.   CHEMICAL COMMUNICATIONS

Bioorthogonal Labeling, Bioimaging, and Photocytotoxicity Studies of Phosphorescent Ruthenium(II) Polypyridine Dibenzocyclooctyne Complexes

(2015) Tommy Siu-Ming Tang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhenium(I) polypyridine dibenzocyclooctyne complexes as phosphorescent bioorthogonal probes: Synthesis, characterization, emissive behavior, and biolabeling properties

(2015) Alex Wing-Tat Choi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Bespoke Photoreductants: Tungsten Arylisocyanides

(2015) Wesley Sattler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cyclometalated iridium(iii) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents

(2015) Liang He et al.   Chemical Science

Hypoxia-specific ultrasensitive detection of tumours and cancer cells in vivo

(2015) Xianchuang Zheng et al.   Nature Communications

Ultrasmall Phosphorescent Polymer Dots for Ratiometric Oxygen Sensing and Photodynamic Cancer Therapy

(2014) Huifang Shi et al.   ADVANCED FUNCTIONAL MATERIALS

Dinuclear Ruthenium(II) Complexes as Two-Photon, Time-Resolved Emission Microscopy Probes for Cellular DNA

(2014) Elizabeth Baggaley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bis(dipyridophenazine)(2-(2-pyridyl)pyrimidine-4-carboxylic acid)ruthenium(II) Complex with Anticancer Action upon Photodeprotection

(2014) Tanmaya Joshi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Endoplasmic reticulum targeted chemotherapeutics: the remarkable photo-cytotoxicity of an oxovanadium(iv) vitamin-B6 complex in visible light

(2014) Samya Banerjee et al.   CHEMICAL COMMUNICATIONS

When self-assembly meets biology: luminescent platinum complexes for imaging applications

(2014) Matteo Mauro et al.   CHEMICAL SOCIETY REVIEWS

Marked Improvement in Photoinduced Cell Death by a New Tris-heteroleptic Complex with Dual Action: Singlet Oxygen Sensitization and Ligand Dissociation

(2014) Bryan A. Albani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide-Bridged Dinuclear Ru(II) Complex for Mitochondrial Targeted Monitoring of Dynamic Changes to Oxygen Concentration and ROS Generation in Live Mammalian Cells

(2014) Aaron Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of an orthogonal ZnSalen/Salophen library as a colour palette for one- and two-photon live cell imaging

(2014) Da Xie et al.   Chemical Science

Mitochondria-targeting cyclometalated iridium(III)–PEG complexes with tunable photodynamic activity

(2013) Steve Po-Yam Li et al.   BIOMATERIALS

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Exploitation of Long-Lived 3IL Excited States for Metal–Organic Photodynamic Therapy: Verification in a Metastatic Melanoma Model

(2013) Richard Lincoln et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation of Powerful Tungsten Reductants by Visible Light Excitation

(2013) Wesley Sattler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential Dual-Action Ru(II) Complex

(2013) Mark A. Sgambellone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic Control Over Photoinduced Electron Transfer in Phosphorescence Zinc Sensors

(2013) Hana Woo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photophysical and cellular uptake properties of novel phosphorescent cyclometalated iridium(iii) bipyridine d-fructose complexes

(2013) Kenneth Kam-Wing Lo et al.   Metallomics

A Phosphorescent Rhenium(I) Tricarbonyl Polypyridine Complex Appended with a Fructose Pendant That Exhibits Photocytotoxicity and Enhanced Uptake by Breast Cancer Cells

(2013) Kenneth Yin Zhang et al.   ORGANOMETALLICS

New cyclometallated Ru(ii) complex for potential application in photochemotherapy?

(2013) Bryan A. Albani et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Induced self-assembly and disassembly of water-soluble alkynylplatinum(ii) terpyridyl complexes with “switchable” near-infrared (NIR) emission modulated by metal–metal interactions over physiological pH: demonstration of pH-responsive NIR luminescent probes in cell-imaging studies

(2013) Clive Yik-Sham Chung et al.   Chemical Science

Ratiometric Molecular Sensor for Monitoring Oxygen Levels in Living Cells

(2012) Toshitada Yoshihara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photodynamic Effect in Near-IR Light by a Photocytotoxic Iron(III) Cellular Imaging Agent

(2012) Uttara Basu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclometalated iridium(iii) polypyridine dibenzocyclooctyne complexes as the first phosphorescent bioorthogonal probes

(2012) Kenneth Kam-Wing Lo et al.   CHEMICAL COMMUNICATIONS

Lighting the way to see inside the live cell with luminescent transition metal complexes

(2012) Elizabeth Baggaley et al.   COORDINATION CHEMISTRY REVIEWS

Applications of luminescent inorganic and organometallic transition metal complexes as biomolecular and cellular probes

(2012) Kenneth Kam-Wing Lo et al.   DALTON TRANSACTIONS

Emissive Behavior, Cytotoxic Activity, Cellular Uptake, and PEGylation Properties of New Luminescent Rhenium(I) Polypyridine Poly(ethylene glycol) Complexes

(2012) Alex Wing-Tat Choi et al.   INORGANIC CHEMISTRY

A Luminescent and Biocompatible PhotoCORM

(2012) Agustin E. Pierri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

(2012) Brock S. Howerton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions

(2011) Ellen M. Sletten et al.   ACCOUNTS OF CHEMICAL RESEARCH

Luminescent metal complexes of d6, d8 and d10 transition metal centres

(2011) Vivian Wing-Wah Yam et al.   CHEMICAL COMMUNICATIONS

Phosphorescent heavy-metal complexes for bioimaging

(2011) Qiang Zhao et al.   CHEMICAL SOCIETY REVIEWS

Environmental effects on the photophysics of transition metal complexes with dipyrido[2,3-a:3′,2′-c]phenazine (dppz) and related ligands

(2011) Andrew W. McKinley et al.   COORDINATION CHEMISTRY REVIEWS

Phosphorescent Sensor for Biological Mobile Zinc

(2011) Youngmin You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphorescent Sensor for Robust Quantification of Copper(II) Ion

(2011) Youngmin You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dye-Sensitized Solar Cells

(2010) Anders Hagfeldt et al.   CHEMICAL REVIEWS

Phosphorescent chemosensors based on heavy-metal complexes

(2010) Qiang Zhao et al.   CHEMICAL SOCIETY REVIEWS

Modification of Luminescent Iridium(III) Polypyridine Complexes with Discrete Poly(ethylene glycol) (PEG) Pendants: Synthesis, Emissive Behavior, Intracellular Uptake, and PEGylation Properties

(2010) Steve Po-Yam Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cobalt(ii) complexes of terpyridine bases as photochemotherapeutic agents showing cellular uptake and photocytotoxicity in visible light

(2010) Sovan Roy et al.   DALTON TRANSACTIONS

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-metal phosphors with cyclometalating ligands: fundamentals and applications

(2009) Yun Chi et al.   CHEMICAL SOCIETY REVIEWS

Photoactivated chemotherapy (PACT): the potential of excited-state d-block metals in medicine

(2009) Nicola J. Farrer et al.   DALTON TRANSACTIONS

A ruthenium(II) polypyridyl complex for direct imaging of DNA structure in living cells

(2009) Martin R. Gill et al.   Nature Chemistry

Novel Luminescent Tricarbonylrhenium(I) Polypyridine Tyramine-Derived Dipicolylamine Complexes as Sensors for Zinc(II) and Cadmium(II) Ions

(2009) Man-Wai Louie et al.   ORGANOMETALLICS