Successively activatable ultrasensitive probe for imaging tumour acidity and hypoxia

In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging

(2016) Dario L. Longo et al.   CANCER RESEARCH

Spatiotemporal Targeting of a Dual-Ligand Nanoparticle to Cancer Metastasis

(2015) Elizabeth Doolittle et al.   ACS Nano

Highly sensitive DNA detection using cascade amplification strategy based on hybridization chain reaction and enzyme-induced metallization

(2015) Xu Yu et al.   BIOSENSORS & BIOELECTRONICS

Quantum dot/antibody conjugates for in vivo cytometric imaging in mice

(2015) Hee-Sun Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein MRI contrast agent with unprecedented metal selectivity and sensitivity for liver cancer imaging

(2015) Shenghui Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-specific ultrasensitive detection of tumours and cancer cells in vivo

(2015) Xianchuang Zheng et al.   Nature Communications

pH-Responsive Reversible PEGylation Improves Performance of Antineoplastic Agent

(2015) Diankui Sun et al.   Advanced Healthcare Materials

A Smart “Sense-Act-Treat” System: Combining a Ratiometric pH Sensor with a Near Infrared Therapeutic Gold Nanocage

(2014) Peng Shi et al.   ADVANCED MATERIALS

Ultra-pH-Sensitive Nanoprobe Library with Broad pH Tunability and Fluorescence Emissions

(2014) Xinpeng Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing

(2014) Adam J Shuhendler et al.   NATURE BIOTECHNOLOGY

Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR

(2014) Anne-Theres Henze et al.   Nature Communications

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

In vivo imaging of glucose uptake and metabolism in tumors

(2013) Simon Walker-Samuel et al.   NATURE MEDICINE

Image-guided cancer surgery using near-infrared fluorescence

(2013) Alexander L. Vahrmeijer et al.   Nature Reviews Clinical Oncology

Real-time In Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides

(2012) E. N. Savariar et al.   CANCER RESEARCH

Sensitive and Convenient Detection of microRNAs Based on Cascade Amplification by Catalytic DNAzymes

(2012) Tian Tian et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ultra-Small, Highly Stable, and Sensitive Dual Nanosensors for Imaging Intracellular Oxygen and pH in Cytosol

(2012) Xu-dong Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Activity-Based Near-Infrared Glucuronide Trapping Probe for Imaging β-Glucuronidase Expression in Deep Tissues

(2012) Ta-Chun Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli

(2012) Kejin Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Patient-derived tumour xenografts as models for oncology drug development

(2012) John J. Tentler et al.   Nature Reviews Clinical Oncology

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

The FLARE™ Intraoperative Near-Infrared Fluorescence Imaging System: A First-in-Human Clinical Trial in Breast Cancer Sentinel Lymph Node Mapping

(2009) Susan L. Troyan et al.   ANNALS OF SURGICAL ONCOLOGY

Recent progress in tumor pH targeting nanotechnology

(2008) Eun Seong Lee et al.   JOURNAL OF CONTROLLED RELEASE

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

(2008) Ferdia A. Gallagher et al.   NATURE

Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes

(2008) Yasuteru Urano et al.   NATURE MEDICINE

A Ratiometric Fluorescent Probe for Cysteine and Homocysteine Displaying a Large Emission Shift

(2008) Weiying Lin et al.   ORGANIC LETTERS