Fighting against Drug‐Resistant Tumors using a Dual‐Responsive Pt(IV)/Ru(II) Bimetallic Polymer

A Multiaction and Multitarget Ru(II)-Pt(IV) Conjugate Combining Cancer Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers

(2020) Johannes Karges et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overcoming Resistance to Platinum-Based Drugs in Ovarian Cancer by Salinomycin and Its Derivatives—An In Vitro Study

(2020) Marcin Michalak et al.   MOLECULES

Self-Assembling Endogenous Biliverdin as a Versatile Near-Infrared Photothermal Nanoagent for Cancer Theranostics

(2019) Ruirui Xing et al.   ADVANCED MATERIALS

Near‐Infrared Photoactivatable Semiconducting Polymer Nanoblockaders for Metastasis‐Inhibited Combination Cancer Therapy

(2019) Jingchao Li et al.   ADVANCED MATERIALS

Cancer Cell Membrane‐Coated Nanoparticles for Personalized Therapy in Patient‐Derived Xenograft Models

(2019) Lang Rao et al.   ADVANCED FUNCTIONAL MATERIALS

Dual Drug Backboned Shattering Polymeric Theranostic Nanomedicine for Synergistic Eradication of Patient-Derived Lung Cancer

(2018) Yuwei Cong et al.   ADVANCED MATERIALS

Effects of the Bidentate Ligand on the Photophysical Properties, Cellular Uptake, and (Photo)cytotoxicity of Glycoconjugates Based on the [Ru(tpy)(NN)(L)]2+ Scaffold

(2018) Lucien N. Lameijer et al.   CHEMISTRY-A EUROPEAN JOURNAL

Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance

(2018) Xiang Ling et al.   NANO LETTERS

New Ru(ii) photocages operative with near-IR light: new platform for drug delivery in the PDT window

(2018) Malik H. Al-Afyouni et al.   Chemical Science

Photodamaging Mitochondrial DNA to Overcome Cisplatin Resistance by a Ru(II)-Pt(II) Bimetallic Complex

(2018) Yue Zheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Using single nucleotide variations in single-cell RNA-seq to identify subpopulations and genotype-phenotype linkage

(2018) Olivier Poirion et al.   Nature Communications

Transient photocyclization in ruthenium(ii) polypyridine complexes of indolamines

(2017) G. Carrone et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Co-Delivery of Cisplatin Prodrug and Chlorin e6 by Mesoporous Silica Nanoparticles for Chemo-Photodynamic Combination Therapy to Combat Drug Resistance

(2016) Wei Zhang et al.   ACS Applied Materials & Interfaces

An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo

(2016) Wen Sun et al.   ADVANCED MATERIALS

A Platinum(IV) Anticancer Prodrug Targeting Nucleotide Excision Repair To Overcome Cisplatin Resistance

(2016) Zhigang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overcoming tumor resistance to cisplatin by cationic lipid-assisted prodrug nanoparticles

(2016) Zhi-Ting Cao et al.   BIOMATERIALS

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution

(2016) Jinchuan Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cisplatin binding to human serum albumin: a structural study

(2015) Giarita Ferraro et al.   CHEMICAL COMMUNICATIONS

A Nanoparticle Cocktail: Temporal Release of Predefined Drug Combinations

(2015) Rakesh K. Pathak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combination of Ru(ii) complexes and light: new frontiers in cancer therapy

(2015) Cristina Mari et al.   Chemical Science

Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells

(2015) Kyu-Tae Kim et al.   GENOME BIOLOGY

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

(2012) Brock S. Howerton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metallofullerene nanoparticles circumvent tumor resistance to cisplatin by reactivating endocytosis

(2010) X.-J. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy

(2007) Matthew D. Hall et al.   Annual Review of Pharmacology and Toxicology