The role of NAD and NAD precursors on longevity and lifespan modulation in the budding yeast, Saccharomyces cerevisiae

Loss of Smi1, a protein involved in cell wall synthesis, extends replicative lifespan by enhancing rDNA stability in Saccharomyces cerevisiae

(2021) Sujin Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Equilibrative Nucleoside Transporters Mediate the Import of Nicotinamide Riboside and Nicotinic Acid Riboside into Human Cells

(2021) Andrey Kropotov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Creating enzymes and self-sufficient cells for biosynthesis of the non-natural cofactor nicotinamide cytosine dinucleotide

(2021) Xueying Wang et al.   Nature Communications

The crosstalk of NAD, ROS and autophagy in cellular health and ageing

(2020) Lucia Sedlackova et al.   BIOGERONTOLOGY

Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects

(2020) Tamas Kiss et al.   GeroScience

NAD+ Metabolism and Regulation: Lessons From Yeast

(2020) Trevor Croft et al.   Biomolecules

Genomic Considerations for the Modification of Saccharomyces cerevisiae for Biofuel and Metabolite Biosynthesis

(2020) James T. Arnone   Microorganisms

Engineering Escherichia coli lifespan for enhancing chemical production

(2020) Liang Guo et al.   Nature Catalysis

TORC1 signaling regulates cytoplasmic pH through Sir2 in yeast

(2020) Mayur Nimbadas Devare et al.   AGING CELL

The flip side of sirtuins: the emerging roles of protein acetyltransferases in aging

(2020) Prabakaran Nagarajan et al.   Aging-US

NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis

(2020) Nady Braidy et al.   EXPERIMENTAL GERONTOLOGY

An Optimized Competitive-Aging Method Reveals Gene-Drug Interactions Underlying the Chronological Lifespan of Saccharomyces cerevisiae

(2020) J. Abraham Avelar-Rivas et al.   Frontiers in Genetics

Possible Adverse Effects of High-Dose Nicotinamide: Mechanisms and Safety Assessment

(2020) Eun Seong Hwang et al.   Biomolecules

Nicotinamide, Nicotinamide Riboside and Nicotinic Acid—Emerging Roles in Replicative and Chronological Aging in Yeast

(2020) Ivan Orlandi et al.   Biomolecules

In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase

(2020) Maurizio D. Baroni et al.   APOPTOSIS

Mechanisms that Link Chronological Aging to Cellular Quiescence in Budding Yeast

(2020) Karamat Mohammad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Location, Location, Location: Compartmentalization of NAD+ Synthesis and Functions in Mammalian Cells

(2020) Xiaolu A. Cambronne et al.   TRENDS IN BIOCHEMICAL SCIENCES

Independent regulation of age associated fat accumulation and longevity

(2020) Anthony O. Beas et al.   Nature Communications

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast

(2020) Pamela Dakik et al.   Oncotarget

Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span

(2020) Ke Zou et al.   Science Advances

Insights into the Conserved Regulatory Mechanisms of Human and Yeast Aging

(2020) Rashmi Dahiya et al.   Biomolecules

Healthful Aging Mediated by Inhibition of Oxidative Stress

(2020) Stephen F. Vatner et al.   AGEING RESEARCH REVIEWS

Gene repression in S. cerevisiae—looking beyond Sir-dependent gene silencing

(2020) Safia Mahabub Sauty et al.   CURRENT GENETICS

Amino acids whose intracellular levels change most during aging alter chronological lifespan of fission yeast

(2020) Charalampos Rallis et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Biosynthesis of medicinal tropane alkaloids in yeast

(2020) Prashanth Srinivasan et al.   NATURE

A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast

(2020) Sara N Mouton et al.   eLife

The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation

(2020) Ivana Bjedov et al.   Genes

Mechanisms to reduce the cytotoxicity of pharmacological nicotinamide concentrations in the pathogenic fungus Candida albicans

(2020) Rahul Ghugari et al.   FEBS Journal

Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective

(2020) Joshua Adedeji Bolarin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

NAD+ metabolism and its roles in cellular processes during ageing

(2020) Anthony J. Covarrubias et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Healthy Lifestyle Recommendations: Do the Beneficial Effects Originate from NAD+ Amount at the Cellular Level?

(2020) Borut Poljsak et al.   Oxidative Medicine and Cellular Longevity

Deletion of the GAPDH gene contributes to genome stability in Saccharomyces cerevisiae

(2020) Miki Hanasaki et al.   Scientific Reports

Keeping the balance in NAD metabolism

(2019) Øyvind Strømland et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor

(2019) Yuxue Liu et al.   ACS Catalysis

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

(2019) Didac Carmona-Gutierrez et al.   Nature Communications

The copper-sensing transcription factor Mac1, the histone deacetylase Hst1, and nicotinic acid regulate de novo NAD+ biosynthesis in budding yeast

(2019) Christol James Theoga Raj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease

(2019) Hisayuki Amano et al.   Cell Metabolism

Escherichia coli Strain Designed for Characterizing in Vivo Functions of Nicotinamide Adenine Dinucleotide Analogues

(2019) Lei Wang et al.   ORGANIC LETTERS

Dual control of NAD+ synthesis by purine metabolites in yeast

(2019) Benoît Pinson et al.   eLife

Some naturally occurring compounds that increase longevity and stress resistance in model organisms of aging

(2019) Darío R. Gómez-Linton et al.   BIOGERONTOLOGY

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

(2019) Stefano Tarantini et al.   Redox Biology

Updates on the epigenetic roles of sirtuins

(2019) Tatsiana Kosciuk et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast

(2019) Karolina Stępień et al.   BIOGERONTOLOGY

NAD+ in Brain Aging and Neurodegenerative Disorders

(2019) Sofie Lautrup et al.   Cell Metabolism

NAD Analogs in Aid of Chemical Biology and Medicinal Chemistry

(2019) Anais Depaix et al.   MOLECULES

Stress and ageing in yeast

(2019) Ian W Dawes et al.   FEMS YEAST RESEARCH

The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

(2019) Yahyah Aman et al.   MECHANISMS OF AGEING AND DEVELOPMENT

NAD metabolism: Implications in aging and longevity

(2018) Keisuke Yaku et al.   AGEING RESEARCH REVIEWS

Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes

(2018) Nady Braidy et al.   ANTIOXIDANTS & REDOX SIGNALING

The yeast replicative aging model

(2018) Chong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

(2018) Sarah J. Mitchell et al.   Cell Metabolism

Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence

(2018) Luis Rajman et al.   Cell Metabolism

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

(2018) Jun Yoshino et al.   Cell Metabolism

Low doses of DNA damaging agents extend Saccharomyces cerevisiae chronological lifespan by promoting entry into quiescence

(2018) Emily M. Ross et al.   EXPERIMENTAL GERONTOLOGY

Tschimganine and its derivatives extend the chronological life span of yeast via activation of the Sty1 pathway

(2018) Takahide Hibi et al.   GENES TO CELLS

Some Metabolites Act as Second Messengers in Yeast Chronological Aging

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A functional link between NAD+homeostasis and N-terminal protein acetylation inSaccharomyces cerevisiae

(2018) Trevor Croft et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Emergence of the Nicotinamide Riboside Kinases in the regulation of NAD+ Metabolism

(2018) Rachel S Fletcher et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Functional Replacement of Histidine in Proteins To Generate Noncanonical Amino Acid Dependent Organisms

(2018) Fei Gan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward an orthogonal central dogma

(2018) Chang C Liu et al.   Nature Chemical Biology

Reshaping the Active Pocket of Amine Dehydrogenases for Asymmetric Synthesis of Bulky Aliphatic Amines

(2018) Fei-Fei Chen et al.   ACS Catalysis

An integrated microfluidic device for the sorting of yeast cells using image processing

(2018) Bo Yang Yu et al.   Scientific Reports

Heat-induced longevity in budding yeast requires respiratory metabolism and glutathione recycling

(2018) Marina Musa et al.   Aging-US

Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis

(2018) Tao Yu et al.   CELL

Emerging applications for DNA writers and molecular recorders

(2018) Fahim Farzadfard et al.   SCIENCE

Resveratrol: Twenty Years of Growth, Development and Controversy

(2018) John M. Pezzuto   Biomolecules & Therapeutics

Disorders in NADPH generation via pentose phosphate pathway influence the reproductive potential of the Saccharomyces cerevisiae yeast due to changes in redox status

(2018) Magdalena Kwolek-Mirek et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Altered Expression of Mitochondrial NAD+ Carriers Influences Yeast Chronological Lifespan by Modulating Cytosolic and Mitochondrial Metabolism

(2018) Ivan Orlandi et al.   Frontiers in Genetics

NAD Metabolism in Cancer Therapeutics

(2018) Keisuke Yaku et al.   Frontiers in Oncology

Nutritional Control of Chronological Aging and Heterochromatin in Saccharomyces cerevisiae

(2017) David F. McCleary et al.   GENETICS

No Beneficial Effects of Resveratrol on the Metabolic Syndrome: A Randomized Placebo-Controlled Clinical Trial

(2017) Thomas Nordstrøm Kjær et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The role of declining adaptive homeostasis in ageing

(2017) Laura C. D. Pomatto et al.   JOURNAL OF PHYSIOLOGY-LONDON

Emissive Synthetic Cofactors: An Isomorphic, Isofunctional, and Responsive NAD+ Analogue

(2017) Alexander R. Rovira et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nicotinamide supplementation phenocopies SIR2 inactivation by modulating carbon metabolism and respiration during yeast chronological aging

(2017) Ivan Orlandi et al.   MECHANISMS OF AGEING AND DEVELOPMENT

NAD and the aging process: Role in life, death and everything in between

(2017) Claudia C.S. Chini et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome

(2017) Hokuto Ohtsuka et al.   MOLECULAR MICROBIOLOGY

Synthetic recording and in situ readout of lineage information in single cells

(2017) Kirsten L. Frieda et al.   NATURE

Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

(2017) Pete A. Williams et al.   SCIENCE

NAD + in Aging: Molecular Mechanisms and Translational Implications

(2017) Evandro F. Fang et al.   TRENDS IN MOLECULAR MEDICINE

Synthetic Cofactor-Linked Metabolic Circuits for Selective Energy Transfer

(2017) Lei Wang et al.   ACS Catalysis

Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state

(2017) Anna Leonov et al.   Oncotarget

Mutations that Allow SIR2 Orthologs to Function in a NAD + -Depleted Environment

(2017) Caitlin R. Ondracek et al.   Cell Reports

Nutritional Control of Chronological Aging and Heterochromatin in Saccharomyces cerevisiae

(2017) David F. McCleary et al.   GENETICS

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

(2017) Rachel S. Fletcher et al.   Molecular Metabolism

DNA polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease

(2016) Magdalena Misiak et al.   AGING CELL

A survey of synthetic nicotinamide cofactors in enzymatic processes

(2016) Caroline E. Paul et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Metal-based superoxide dismutase and catalase mimics reduce oxidative stress biomarkers and extend life span of Saccharomyces cerevisiae

(2016) Thales de P. Ribeiro et al.   BIOCHEMICAL JOURNAL

Engineering Cellular Metabolism

(2016) Jens Nielsen et al.   CELL

NAD + Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

(2016) Evandro Fei Fang et al.   Cell Metabolism

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

(2016) Kathryn F. Mills et al.   Cell Metabolism

Single-Cell Analysis of Growth in Budding Yeast and Bacteria Reveals a Common Size Regulation Strategy

(2016) Ilya Soifer et al.   CURRENT BIOLOGY

Identification of the Target of the Retrograde Response that Mediates Replicative Lifespan Extension in Saccharomyces cerevisiae

(2016) J. C. Jiang et al.   GENETICS

The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae

(2016) Marc R. Gartenberg et al.   GENETICS

Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes

(2016) Tanja Knaus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A fluidic circuit based, high-efficiency and large-scale single cell trap

(2016) Lu Mi et al.   LAB ON A CHIP

Essential role of B ordetella NadC in a quinolinate salvage pathway for NAD biosynthesis

(2016) Timothy J. Brickman et al.   MOLECULAR MICROBIOLOGY

New tools for reconstruction and heterologous expression of natural product biosynthetic gene clusters

(2016) Yunzi Luo et al.   NATURAL PRODUCT REPORTS

Rewiring Escherichia coli for carbon-dioxide fixation

(2016) Cheryl A Kerfeld   NATURE BIOTECHNOLOGY

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

(2016) Michael S. Bonkowski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

NAD+ as the Link Between Oxidative Stress, Inflammation, Caloric Restriction, Exercise, DNA Repair, Longevity, and Health Span

(2016) Borut Poljsak et al.   REJUVENATION RESEARCH

Synthetic recombinase-based state machines in living cells

(2016) N. Roquet et al.   SCIENCE

Six plant extracts delay yeast chronological aging through different signaling pathways

(2016) Vicky Lutchman et al.   Oncotarget

Recent Progress of Microfluidics in Translational Applications

(2016) Zongbin Liu et al.   Advanced Healthcare Materials

Chronological Lifespan in Yeast Is Dependent on the Accumulation of Storage Carbohydrates Mediated by Yak1, Mck1 and Rim15 Kinases

(2016) Lu Cao et al.   PLoS Genetics

Genetic Manipulation of Glycogen Allocation Affects Replicative Lifespan in E. coli

(2016) Alex Boehm et al.   PLoS Genetics

The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae

(2016) Marc R. Gartenberg et al.   GENETICS

Communications between Mitochondria, the Nucleus, Vacuoles, Peroxisomes, the Endoplasmic Reticulum, the Plasma Membrane, Lipid Droplets, and the Cytosol during Yeast Chronological Aging

(2016) Pamela Dakik et al.   Frontiers in Genetics

Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation

(2016) Saurabh Sahar et al.   Aging-US

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits

(2015) Christopher Hine et al.   CELL

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

(2015) Carles Cantó et al.   Cell Metabolism

From ribavirin to NAD analogues and back to ribavirin in search for anticancer agents

(2015) Krzysztof W. Pankiewicz et al.   HETEROCYCLIC COMMUNICATIONS

Reduced Ssy1-Ptr3-Ssy5 (SPS) Signaling Extends Replicative Life Span by Enhancing NAD+Homeostasis inSaccharomyces cerevisiae

(2015) Felicia Tsang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-throughput analysis of yeast replicative aging using a microfluidic system

(2015) Myeong Chan Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAD+ in aging, metabolism, and neurodegeneration

(2015) E. Verdin   SCIENCE

Yeast Replicator: A High-Throughput Multiplexed Microfluidics Platform for Automated Measurements of Single-Cell Aging

(2015) Ping Liu et al.   Cell Reports

Protocols and Programs for High-Throughput Growth and Aging Phenotyping in Yeast

(2015) Paul P. Jung et al.   PLoS One

Identification of malic enzyme mutants depending on 1,2,3-triazole moiety-containing nicotinamide adenine dinucleotide analogs

(2014) Shuhua Hou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan

(2014) Tobias Eisenberg et al.   Cell Metabolism

Activation of SIRT3 by the NAD+ Precursor Nicotinamide Riboside Protects from Noise-Induced Hearing Loss

(2014) Kevin D. Brown et al.   Cell Metabolism

Regulation of NAD+ metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiae

(2014) Michiko Kato et al.   DNA REPAIR

Quantification of Protein Copy Number in Yeast: The NAD+ Metabolome

(2014) Szu-Chieh Mei et al.   PLoS One

Rewiring yeast osmostress signalling through the MAPK network reveals essential and non-essential roles of Hog1 in osmoadaptation

(2014) Roja Babazadeh et al.   Scientific Reports

High-Resolution Profiling of Stationary-Phase Survival Reveals Yeast Longevity Factors and Their Genetic Interactions

(2014) Erika Garay et al.   PLoS Genetics

Enhancement of mitochondrial function correlates with the extension of lifespan by caloric restriction and caloric restriction mimetics in yeast

(2013) Kyung-Mi Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

Nicotinamide riboside, a trace nutrient in foods, is a Vitamin B3 with effects on energy metabolism and neuroprotection

(2013) Yuling Chi et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Tpo1-mediated spermine and spermidine export controls cell cycle delay and times antioxidant protein expression during the oxidative stress response

(2013) Antje Krüger et al.   EMBO REPORTS

Secretion of Quinolinic Acid, an Intermediate in the Kynurenine Pathway, for Utilization in NAD + Biosynthesis in the Yeast Saccharomyces cerevisiae

(2013) Kazuto Ohashi et al.   EUKARYOTIC CELL

Yeast sirtuins and the regulation of aging

(2013) Margaret B. Wierman et al.   FEMS YEAST RESEARCH

Reactive oxygen species, ageing and the hormesis police

(2013) Paula Ludovico et al.   FEMS YEAST RESEARCH

Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation inSaccharomyces cerevisiae

(2013) Erwin Swinnen et al.   FEMS YEAST RESEARCH

Ribosomal DNA and cellular senescence: new evidence supporting the connection between rDNA and aging

(2013) Austen R. D. Ganley et al.   FEMS YEAST RESEARCH

A network of interorganellar communications underlies cellular aging

(2013) Anna Leonov et al.   IUBMB LIFE

Activation of Protein Kinase C-Mitogen-activated Protein Kinase Signaling in Response to Inositol Starvation Triggers Sir2p-dependent Telomeric Silencing in Yeast

(2013) Sojin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Time line of redox events in aging postmitotic cells

(2013) Nicolas Brandes et al.   eLife

Molecular phenotyping of aging in single yeast cells using a novel microfluidic device

(2012) Zhengwei Xie et al.   AGING CELL

Mitochondrial Energy Metabolism and Redox Signaling in Brain Aging and Neurodegeneration

(2012) Fei Yin et al.   ANTIOXIDANTS & REDOX SIGNALING

Lack of Sir2 increases acetate consumption and decreases extracellular pro-aging factors

(2012) Nadia Casatta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

PHB granules are attached to the nucleoid via PhaM in Ralstonia eutropha

(2012) Andreas Wahl et al.   BMC MICROBIOLOGY

Mitochondrial Respiratory Thresholds Regulate Yeast Chronological Life Span and its Extension by Caloric Restriction

(2012) Alejandro Ocampo et al.   Cell Metabolism

Replicative and Chronological Aging in Saccharomyces cerevisiae

(2012) Valter D. Longo et al.   Cell Metabolism

Isonicotinamide Enhances Sir2 Protein-mediated Silencing and Longevity in Yeast by Raising Intracellular NAD+Concentration

(2012) Julie M. McClure et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-carbon metabolites, polyphenols and vitamins influence yeast chronological life span in winemaking conditions

(2012) Helena Orozco et al.   Microbial Cell Factories

Mimicking Nature: Synthetic Nicotinamide Cofactors for C═C Bioreduction Using Enoate Reductases

(2012) Caroline E. Paul et al.   ORGANIC LETTERS

Single Cell Analysis of Yeast Replicative Aging Using a New Generation of Microfluidic Device

(2012) Yi Zhang et al.   PLoS One

Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform

(2012) S. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis of NAD analogs to develop bioorthogonal redox system

(2012) DeBin Ji et al.   Science China-Chemistry

Microfluidics for Manipulating Cells

(2012) Xuan Mu et al.   Small

The phenomenon of resveratrol: redefining the virtues of promiscuity

(2011) John M. Pezzuto   Annals of the New York Academy of Sciences

In search of housekeeping pathways that regulate longevity

(2011) Adam Beach et al.   CELL CYCLE

A genomic analysis of chronological longevity factors in budding yeast

(2011) Christopher R. Burtner et al.   CELL CYCLE

Regulation of Yeast Chronological Life Span by TORC1 via Adaptive Mitochondrial ROS Signaling

(2011) Yong Pan et al.   Cell Metabolism

Rehab of NAD(P)-Dependent Enzymes with NAD(P)-Based Inhibitors

(2011) K. Felczak et al.   CURRENT MEDICINAL CHEMISTRY

Mitochondria, reactive oxygen species, and chronological aging: A message from yeast

(2011) Yong Pan   EXPERIMENTAL GERONTOLOGY

Phosphate-responsive Signaling Pathway Is a Novel Component of NAD+Metabolism inSaccharomyces cerevisiae

(2011) Shu-Ping Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Method for High-Throughput Quantitative Analysis of Yeast Chronological Life Span

(2011) C. J. Murakami et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Nrt1 and Tna1-Independent Export of NAD+ Precursor Vitamins Promotes NAD+ Homeostasis and Allows Engineering of Vitamin Production

(2011) Peter Belenky et al.   PLoS One

Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae

(2011) F. M. Roelants et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors

(2011) Shuhua Hou et al.   TETRAHEDRON LETTERS

Replicative Age Induces Mitotic Recombination in the Ribosomal RNA Gene Cluster of Saccharomyces cerevisiae

(2011) Derek L. Lindstrom et al.   PLoS Genetics

YODA: Software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast

(2010) Brady Olsen et al.   BMC BIOINFORMATICS

A molecular mechanism of chronological aging in yeast

(2010) Christopher R. Burtner et al.   CELL CYCLE

Bacterial aging: from mechanistic basis to evolutionary perspective

(2010) Krzysztof Książek   CELLULAR AND MOLECULAR LIFE SCIENCES

SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

(2010) Michelle Pacholec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

(2010) Richard A. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Lessons on longevity from budding yeast

(2010) Matt Kaeberlein   NATURE

Protein Acetylation Microarray Reveals that NuA4 Controls Key Metabolic Target Regulating Gluconeogenesis

(2009) Yu-yi Lin et al.   CELL

Identification of Isn1 and Sdt1 as Glucose- and Vitamin-regulated Nicotinamide Mononucleotide and Nicotinic Acid Mononucleotide 5′-Nucleotidases Responsible for Production of Nicotinamide Riboside and Nicotinic Acid Riboside

(2009) Katrina L. Bogan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assimilation of Endogenous Nicotinamide Riboside Is Essential for Calorie Restriction-mediated Life Span Extension inSaccharomyces cerevisiae

(2009) Shu-Ping Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitation of NAD+biosynthesis from the salvage pathway inSaccharomyces cerevisiae

(2009) Jennifer Sporty et al.   YEAST

Tor1/Sch9-Regulated Carbon Source Substitution Is as Effective as Calorie Restriction in Life Span Extension

(2009) Min Wei et al.   PLoS Genetics

Replicative Aging in Yeast: The Means to the End

(2008) K.A. Steinkraus et al.   Annual Review of Cell and Developmental Biology

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

Comprehensive X-ray Structural Studies of the Quinolinate Phosphoribosyl Transferase (BNA6) fromSaccharomyces cerevisiae‡

(2008) Eric di Luccio et al.   BIOCHEMISTRY

Negative regulation of apoptosis in yeast

(2008) Esther Owsianowski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Saccharomyces cerevisiae YOR071CEncodes the High Affinity Nicotinamide Riboside Transporter Nrt1

(2008) Peter A. Belenky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 confers protection against UVB- and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes

(2008) Cong Cao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation

(2008) A. B. Lindner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA