Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma

(2016) Pete A. Williams et al.   Molecular Neurodegeneration

Mitonuclear communication in homeostasis and stress

(2016) Pedro M. Quirós et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia

(2016) Feng Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

(2016) Valentina Gandin et al.   Nature Communications

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

(2016) Leah C. Graham et al.   Scientific Reports

NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies

(2016) Yousuf O. Ali et al.   PLOS BIOLOGY

Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis

(2015) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

(2015) Sarah E. Calvo et al.   NUCLEIC ACIDS RESEARCH

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

(2014) M Di Stefano et al.   CELL DEATH AND DIFFERENTIATION

The Complex Role of Neuroinflammation in Glaucoma

(2014) I. Soto et al.   Cold Spring Harbor Perspectives in Medicine

Mitochondrial quality control and communications with the nucleus are important in maintaining mitochondrial function and cell health

(2013) Vassilios N. Kotiadis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

(2013) Ana P. Gomes et al.   CELL

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

From Mechanosensitivity to Inflammatory Responses: New Players in the Pathology of Glaucoma

(2013) David Križaj et al.   CURRENT EYE RESEARCH

Why does Brain Metabolism not Favor Burning of Fatty Acids to Provide Energy? - Reflections on Disadvantages of the Use of Free Fatty Acids as Fuel for Brain

(2013) Peter Schönfeld et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Under Pressure: Cellular and Molecular Responses During Glaucoma, a Common Neurodegeneration with Axonopathy

(2012) Robert W. Nickells et al.   Annual Review of Neuroscience

Oxidative stress and mitochondrial dysfunction in glaucoma

(2012) Vicki Chrysostomou et al.   CURRENT OPINION IN PHARMACOLOGY

Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2

(2012) Brooke M. Baker et al.   PLoS Genetics

BamTools: a C++ API and toolkit for analyzing and managing BAM files

(2011) D. W. Barnett et al.   BIOINFORMATICS

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

(2011) Gareth R. Howell et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial dysfunction in glaucoma and emerging bioenergetic therapies

(2010) Shanjean Lee et al.   EXPERIMENTAL EYE RESEARCH

Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons

(2010) Jonathan Gilley et al.   PLOS BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS