Microfluidics for Manipulating Cells

Chemical Recognition in Cell-Imprinted Polymers

(2012) Kangning Ren et al.   ACS Nano

A Strategy for Depositing Different Types of Cells in Three Dimensions to Mimic Tubular Structures in Tissues

(2012) Bo Yuan et al.   ADVANCED MATERIALS

Separation of bacteria with imprinted polymeric films

(2012) Romana Schirhagl et al.   ANALYST

Aptamer-Enabled Efficient Isolation of Cancer Cells from Whole Blood Using a Microfluidic Device

(2012) Weian Sheng et al.   ANALYTICAL CHEMISTRY

Sensitive and High-Throughput Isolation of Rare Cells from Peripheral Blood with Ensemble-Decision Aliquot Ranking

(2012) Perry G. Schiro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Surface Coating as a Key Parameter in Engineering Neuronal Network Structures In Vitro

(2012) Yi Sun et al.   Biointerphases

Single-cell level co-culture platform for intercellular communication

(2012) Soongweon Hong et al.   Integrative Biology

Dynamic trapping and high-throughput patterning of cells using pneumatic microstructures in an integrated microfluidic device

(2012) Wenming Liu et al.   LAB ON A CHIP

Sorting cells by size, shape and deformability

(2012) Jason P. Beech et al.   LAB ON A CHIP

Three-dimensional microfiber devices that mimic physiological environments to probe cell mechanics and signaling

(2012) Warren C. Ruder et al.   LAB ON A CHIP

Engineers are from PDMS-land, Biologists are from Polystyrenia

(2012) Erwin Berthier et al.   LAB ON A CHIP

A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells

(2012) Joo H. Kang et al.   LAB ON A CHIP

Cellular Microfabrication: Observing Intercellular Interactions Using Lithographically-Defined DNA Capture Sequences

(2012) Hiroaki Onoe et al.   LANGMUIR

Surface-imprinted polymers in microfluidic devices

(2012) Romana Schirhagl et al.   Science China-Chemistry

Electrospun Fiber Template for Replica Molding of Microtopographical Neural Growth Guidance

(2012) Yingyi Liu et al.   Small

Massively Parallel Bacterial and Yeast Suspension Culture on a Chip

(2012) Mingzhe Gan et al.   Small

Aptamer-Mediated Efficient Capture and Release of T Lymphocytes on Nanostructured Surfaces

(2011) Li Chen et al.   ADVANCED MATERIALS

Microfluidic Device with Chemical Gradient for Single-Cell Cytotoxicity Assays

(2011) Masahito Hosokawa et al.   ANALYTICAL CHEMISTRY

Multifunctional Picoliter Droplet Manipulation Platform and Its Application in Single Cell Analysis

(2011) Shu-Qing Gu et al.   ANALYTICAL CHEMISTRY

Negative Enrichment of Target Cells by Microfluidic Affinity Chromatography

(2011) Peng Li et al.   ANALYTICAL CHEMISTRY

High-Throughput Selection, Enumeration, Electrokinetic Manipulation, and Molecular Profiling of Low-Abundance Circulating Tumor Cells Using a Microfluidic System

(2011) Udara Dharmasiri et al.   ANALYTICAL CHEMISTRY

Imaging Single-Cell Signaling Dynamics with a Deterministic High-Density Single-Cell Trap Array

(2011) Kwanghun Chung et al.   ANALYTICAL CHEMISTRY

Micro Total Analysis Systems for Cell Biology and Biochemical Assays

(2011) Michelle L. Kovarik et al.   ANALYTICAL CHEMISTRY

Dendrimer-Mediated Multivalent Binding for the Enhanced Capture of Tumor Cells

(2011) Ja Hye Myung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers

(2011) Shutao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single-cell assays

(2011) Declan Ryan et al.   Biomicrofluidics

Efficient capture of circulating tumor cells with a novel immunocytochemical microfluidic device

(2011) Mary Nora Dickson et al.   Biomicrofluidics

High-throughput size-based rare cell enrichment using microscale vortices

(2011) Soojung Claire Hur et al.   Biomicrofluidics

Surface modification for PDMS-based microfluidic devices

(2011) Jinwen Zhou et al.   ELECTROPHORESIS

High-throughput cell cycle synchronization using inertial forces in spiral microchannels

(2011) Wong Cheng Lee et al.   LAB ON A CHIP

Pumping-induced perturbation of flow in microfluidic channels and its implications for on-chip cell culture

(2011) Jianhua Zhou et al.   LAB ON A CHIP

Programmed trapping of individual bacteria using micrometre-size sieves

(2011) Min-Cheol Kim et al.   LAB ON A CHIP

A microchip-based model wound with multiple types of cells

(2011) Yunyan Xie et al.   LAB ON A CHIP

Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation

(2011) Ali Asgar S. Bhagat et al.   LAB ON A CHIP

Microchip-based immunomagnetic detection of circulating tumor cells

(2011) Kazunori Hoshino et al.   LAB ON A CHIP

Separation of platelets from whole blood using standing surface acoustic waves in a microchannel

(2011) Jeonghun Nam et al.   LAB ON A CHIP

Biomimetic postcapillary expansions for enhancing rare blood cell separation on a microfluidic chip

(2011) Abhishek Jain et al.   LAB ON A CHIP

Engineered approaches to the stem cell microenvironment for cardiac tissue regeneration

(2011) Ebrahim Ghafar-Zadeh et al.   LAB ON A CHIP

Automated cellular sample preparation using a Centrifuge-on-a-Chip

(2011) Albert J. Mach et al.   LAB ON A CHIP

Droplet size based separation by deterministic lateral displacement—separating droplets by cell-induced shrinking

(2011) Haakan N. Joensson et al.   LAB ON A CHIP

An integrated chip for immunofluorescence and its application to analyze lysosomal storage disorders

(2011) Jie Shen et al.   LAB ON A CHIP

Isolation of prostate tumor initiating cells (TICs) through their dielectrophoretic signature

(2011) Alireza Salmanzadeh et al.   LAB ON A CHIP

Using Self-Polymerized Dopamine to Modify the Antifouling Property of Oligo(ethylene glycol) Self-Assembled Monolayers and Its Application in Cell Patterning

(2011) Kang Sun et al.   LANGMUIR

On-chip cell migration assay for quantifying the effect of ethanol on MCF-7 human breast cancer cells

(2011) Xiaowen Huang et al.   Microfluidics and Nanofluidics

Central dogma at the single-molecule level in living cells

(2011) Gene-Wei Li et al.   NATURE

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells

(2011) Chao Ma et al.   NATURE MEDICINE

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Correction: Regulatory Effects of IFN-β on the Development of Experimental Autoimmune Uveoretinitis in B10RIII Mice

(2011) Min Sun et al.   PLoS One

Whole-Teflon microfluidic chips

(2011) K. Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells

(2011) Q. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Entrainment of a Population of Synthetic Genetic Oscillators

(2011) O. Mondragon-Palomino et al.   SCIENCE

Nanoporous Elements in Microfluidics for Multiscale Manipulation of Bioparticles

(2011) Grace D. Chen et al.   Small

Electroactive Microwell Arrays for Highly Efficient Single-Cell Trapping and Analysis

(2011) Soo Hyeon Kim et al.   Small

Localized neurite outgrowth sensing via substrates with alternative rigidities

(2011) Szu-Yuan Chou et al.   Soft Matter

A General Approach for Patterning Multiple Types of Cells Using Holey PDMS Membranes and Microfluidic Channels

(2010) Bo Yuan et al.   ADVANCED FUNCTIONAL MATERIALS

Interfacing droplet microfluidics with chemical separation for cellular analysis

(2010) Daniel T. Chiu   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A differential cell capture assay for evaluating antibody interactions with cell surface targets

(2010) David J. Sherman et al.   ANALYTICAL BIOCHEMISTRY

A Microfluidic Cell Concentrator

(2010) Jay Warrick et al.   ANALYTICAL CHEMISTRY

High-Performance Single Cell Genetic Analysis Using Microfluidic Emulsion Generator Arrays

(2010) Yong Zeng et al.   ANALYTICAL CHEMISTRY

Single-Cell Multiplex Gene Detection and Sequencing with Microfluidically Generated Agarose Emulsions

(2010) Richard Novak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens

(2010) J. Sun et al.   CANCER RESEARCH

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

Quantitative Cell-Based Reporter Gene Assays Using Droplet-Based Microfluidics

(2010) Jean-Christophe Baret et al.   CHEMISTRY & BIOLOGY

Detection and HER2 Expression of Circulating Tumor Cells: Prospective Monitoring in Breast Cancer Patients Treated in the Neoadjuvant GeparQuattro Trial

(2010) S. Riethdorf et al.   CLINICAL CANCER RESEARCH

Development of neurons on micropatterns reveals that growth cone responds to a sharp change of concentration of laminin

(2010) Shige Xing et al.   ELECTROPHORESIS

Ion fluxes, transmembrane potential, and osmotic stabilization: a new dynamic electrophysiological model for eukaryotic cells

(2010) Clair Poignard et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

A stretching device for imaging real-time molecular dynamics of live cells adhering to elastic membranes on inverted microscopes during the entire process of the stretch

(2010) Dong Wang et al.   Integrative Biology

Continuous cell introduction and rapid dynamic lysis for high-throughput single-cell analysis on microfludic chips with hydrodynamic focusing

(2010) Chun-Xiu Xu et al.   JOURNAL OF CHROMATOGRAPHY A

Electrochemical desorption of self-assembled monolayers and its applications in surface chemistry and cell biology

(2010) Kang Sun et al.   JOURNAL OF ELECTROANALYTICAL CHEMISTRY

Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions

(2010) Ken-ichiro Kamei et al.   LAB ON A CHIP

Chemical stimulation of the Arabidopsis thaliana root using multi-laminar flow on a microfluidic chip

(2010) Matthias Meier et al.   LAB ON A CHIP

Continuous sorting of heterogeneous-sized embryoid bodies

(2010) Peter B. Lillehoj et al.   LAB ON A CHIP

Directing the flow of medium in controlled cocultures of HeLa cells and human umbilical vein endothelial cells with a microfluidic device

(2010) Hirokazu Kaji et al.   LAB ON A CHIP

Uniform cell seeding and generation of overlapping gradient profiles in a multiplexed microchamber device with normally-closed valves

(2010) Bobak Mosadegh et al.   LAB ON A CHIP

An integrated microfluidic system for studying cell-microenvironmental interactions versatilely and dynamically

(2010) Wenming Liu et al.   LAB ON A CHIP

Enzyme-assisted photolithography for spatial functionalization of hydrogels

(2010) Zhen Gu et al.   LAB ON A CHIP

Deformability considerations in filtration of biological cells

(2010) Jason S. Kuo et al.   LAB ON A CHIP

Optimization of microfluidic single cell trapping for long-term on-chip culture

(2010) Stefan Kobel et al.   LAB ON A CHIP

Carcinoma-associated fibroblasts promoted tumor spheroid invasion on a microfluidic 3D co-culture device

(2010) Tingjiao Liu et al.   LAB ON A CHIP

Matrix density mediates polarization and lumen formation of endothelial sprouts in VEGF gradients

(2010) Amir Shamloo et al.   LAB ON A CHIP

A simple PDMS-based microfluidic channel design that removes bubbles for long-term on-chip culture of mammalian cells

(2010) Wenfu Zheng et al.   LAB ON A CHIP

Simple haptotactic gradient generation within a triangular microfluidic channel

(2010) Jungyul Park et al.   LAB ON A CHIP

High-throughput single-cell quantification using simple microwell-based cell docking and programmable time-course live-cell imaging

(2010) Min Cheol Park et al.   LAB ON A CHIP

Stand-alone self-powered integrated microfluidic blood analysis system (SIMBAS)

(2010) Ivan K. Dimov et al.   LAB ON A CHIP

A microfluidic array with cellular valving for single cell co-culture

(2010) Jean-Philippe Frimat et al.   LAB ON A CHIP

In Vitro Model on Glass Surfaces for Complex Interactions between Different Types of Cells

(2010) Zhenling Chen et al.   LANGMUIR

Circulating tumour cells in clinical practice: Methods of detection and possible characterization

(2010) Marianna Alunni-Fabbroni et al.   METHODS

Assay of glioma cell responses to an anticancer drug in a cell-based microfluidic device

(2010) Wenming Liu et al.   Microfluidics and Nanofluidics

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

(2010) J. J. Agresti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

(2010) S. L. Stott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer's Circulation Problem

(2010) J. Kaiser   SCIENCE

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

(2010) Y. Taniguchi et al.   SCIENCE

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Capture and Culturing of Living Cells on Microstructured DNA Substrates

(2010) Stephanie Reisewitz et al.   Small

Surface-Treatment-Induced Three-Dimensional Capillary Morphogenesis in a Microfluidic Platform

(2009) Seok Chung et al.   ADVANCED MATERIALS

Combining nanosurface chemistry and microfluidics for molecular analysis and cell biology

(2009) Yi Sun et al.   ANALYTICA CHIMICA ACTA

Aptamer-Based Microfluidic Device for Enrichment, Sorting, and Detection of Multiple Cancer Cells

(2009) Ye Xu et al.   ANALYTICAL CHEMISTRY

Particle Focusing Mechanisms in Curving Confined Flows

(2009) Daniel R. Gossett et al.   ANALYTICAL CHEMISTRY

Compartmentalization of Chemically Separated Components into Droplets

(2009) J. Scott Edgar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Patterning Mammalian Cells for Modeling Three Types of Naturally Occurring Cell-Cell Interactions

(2009) Zhenling Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Using Azobenzene-Embedded Self-Assembled Monolayers To Photochemically Control Cell Adhesion Reversibly

(2009) Dingbin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Three-Dimensional Nanostructured Substrates toward Efficient Capture of Circulating Tumor Cells

(2009) Shutao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Integrated microfluidic devices for combinatorial cell-based assays

(2009) Zeta Tak For Yu et al.   BIOMEDICAL MICRODEVICES

Simple, fast and high-throughput single-cell analysis on PDMS microfluidic chips

(2009) Linfen Yu et al.   ELECTROPHORESIS

A microfluidic device for characterizing the invasion of cancer cells in 3-D matrix

(2009) Tingjiao Liu et al.   ELECTROPHORESIS

Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids

(2009) Yu-suke Torisawa et al.   Integrative Biology

Micromagnetic–microfluidic blood cleansing device

(2009) Chong Wing Yung et al.   LAB ON A CHIP

Inertial microfluidics

(2009) Dino Di Carlo   LAB ON A CHIP

Laminar flow used as “liquid etch mask” in wet chemical etching to generate glass microstructures with an improved aspect ratio

(2009) Xuan Mu et al.   LAB ON A CHIP

DNA-barcode directed capture and electrochemical metabolic analysis of single mammalian cells on a microelectrode array

(2009) Erik S. Douglas et al.   LAB ON A CHIP

Soft inertial microfluidics for high throughput separation of bacteria from human blood cells

(2009) Zhigang Wu et al.   LAB ON A CHIP

A novel multishear microdevice for studying cell mechanics

(2009) Lien Chau et al.   LAB ON A CHIP

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

(2009) Carlos P. Huang et al.   LAB ON A CHIP

Simultaneous sorting of multiple bacterial targets using integrated Dielectrophoretic–Magnetic Activated Cell Sorter

(2009) Unyoung Kim et al.   LAB ON A CHIP

Inertial microfluidics for continuous particle separation in spiral microchannels

(2009) Sathyakumar S. Kuntaegowdanahalli et al.   LAB ON A CHIP

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

(2009) Jean-Christophe Baret et al.   LAB ON A CHIP

Microfluidic single cell arrays to interrogate signalling dynamics of individual, patient-derived hematopoietic stem cells

(2009) Shannon L. Faley et al.   LAB ON A CHIP

High flow rate microfluidic device for blood plasma separation using a range of temperatures

(2009) Angeles Ivón Rodríguez-Villarreal et al.   LAB ON A CHIP

Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation

(2009) Christopher Moraes et al.   LAB ON A CHIP

Sheathless inertial cell ordering for extreme throughput flow cytometry

(2009) Soojung Claire Hur et al.   LAB ON A CHIP

Selectively modified microfluidic chip for solvent extraction of Radix Salvia Miltiorrhiza using three-phase laminar flow to provide double liquid–liquid interface area

(2009) Xuan Mu et al.   Microfluidics and Nanofluidics

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatiotemporal Control of Apical and Basal Living Subcellular Chemical Environments Through Vertical Phase Separation

(2009) Jui-Ming Yang et al.   Small

Synthesis of Cell-Laden Alginate Hollow Fibers Using Microfluidic Chips and Microvascularized Tissue-Engineering Applications

(2009) Kwang Ho Lee et al.   Small

The Impact of Biomechanics in Tissue Engineering and Regenerative Medicine

(2009) David L. Butler et al.   TISSUE ENGINEERING PART B-REVIEWS

Vascularization Strategies for Tissue Engineering

(2009) Michael Lovett et al.   TISSUE ENGINEERING PART B-REVIEWS

Sizing Subcellular Organelles and Nanoparticles Confined within Aqueous Droplets

(2008) Jennifer C. Gadd et al.   ANALYTICAL CHEMISTRY

Equilibrium Separation and Filtration of Particles Using Differential Inertial Focusing

(2008) Dino Di Carlo et al.   ANALYTICAL CHEMISTRY

Multitarget Dielectrophoresis Activated Cell Sorter

(2008) Unyoung Kim et al.   ANALYTICAL CHEMISTRY

Cell Culture Models in Microfluidic Systems

(2008) Ivar Meyvantsson et al.   Annual Review of Analytical Chemistry

Surface modification by 2-methacryloyloxyethyl phosphorylcholine coupled to a photolabile linker for cell micropatterning

(2008) Kihoon Jang et al.   BIOMATERIALS

Microfluidic high viability neural cell separation using viscoelastically tuned hydrodynamic spreading

(2008) Zhigang Wu et al.   BIOMEDICAL MICRODEVICES

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

(2008) Jenifer Clausell-Tormos et al.   CHEMISTRY & BIOLOGY

Highly Efficient Circulating Tumor Cell Isolation from Whole Blood and Label-Free Enumeration Using Polymer-Based Microfluidics with an Integrated Conductivity Sensor

(2008) André A. Adams et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modular microfluidics for gradient generation

(2008) Kang Sun et al.   LAB ON A CHIP

Drop-based microfluidic devices for encapsulation of single cells

(2008) Sarah Köster et al.   LAB ON A CHIP

Fabrication of a modular tissue construct in a microfluidic chip

(2008) Derek A. Bruzewicz et al.   LAB ON A CHIP

Cell research with physically modified microfluidic channels: A review

(2008) Sun Min Kim et al.   LAB ON A CHIP

Controlled encapsulation of single-cells into monodisperse picolitre drops

(2008) Jon F. Edd et al.   LAB ON A CHIP

Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging

(2008) Vernella Vickerman et al.   LAB ON A CHIP

Droplet microfluidics

(2008) Shia-Yen Teh et al.   LAB ON A CHIP

An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells

(2008) Ken-ichiro Kamei et al.   LAB ON A CHIP

Microfluidics: A new cosset for neurobiology

(2008) Jinyi Wang et al.   LAB ON A CHIP

Cell migration into scaffolds under co-culture conditions in a microfluidic platform

(2008) Seok Chung et al.   LAB ON A CHIP

Metabolic gene regulation in a dynamically changing environment

(2008) Matthew R. Bennett et al.   NATURE

A fast, robust and tunable synthetic gene oscillator

(2008) Jesse Stricker et al.   NATURE

Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells

(2008) M. Chabert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multitarget magnetic activated cell sorter

(2008) J. D. Adams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sheathless Focusing of Microbeads and Blood Cells Based on Hydrophoresis

(2008) Sungyoung Choi et al.   Small