The Relationship Between Alzheimer’s Disease and Skin Diseases: A Review

Alzheimer's disease

(2021) Philip Scheltens et al.   LANCET

The burden of neurological comorbidities in six autoimmune bullous diseases: a population‐based study

(2021) K. Kridin et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Psychiatric comorbidities in patients with hidradenitis suppurativa

(2020) Angelica Misitzis et al.   Dermatologic Therapy

Hidradenitis Suppurativa: An Update on Epidemiology, Phenotypes, Diagnosis, Pathogenesis, Comorbidities and Quality of Life

(2020) Tien V. Nguyen et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Common germline variants of the human APOE gene modulate melanoma progression and survival

(2020) Benjamin N. Ostendorf et al.   NATURE MEDICINE

Tumor Necrosis Factor (TNF) blocking agents are associated with lower risk for Alzheimer’s disease in patients with rheumatoid arthritis and psoriasis

(2020) Mengshi Zhou et al.   PLoS One

Increased risk of Alzheimer’s disease in patients with psoriasis: a nationwide population-based cohort study

(2020) Miri Kim et al.   Scientific Reports

Hidradenitis suppurativa

(2020) Robert Sabat et al.   Nature Reviews Disease Primers

Treatment concerns for bullous pemphigoid in the COVID ‐19 pandemic era

(2020) Seyyede Zeinab Azimi et al.   Dermatologic Therapy

Total IgE , eosinophils, and interleukins 16, 17A , and 23 correlations in severe bullous pemphigoid and treatment implications

(2020) Florentina Silvia Delli et al.   Dermatologic Therapy

Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity

(2020) Vittoria Matafora et al.   EMBO REPORTS

Hidradenitis suppurativa and chromosomal abnormalities: a case report and systematic review of the literature

(2020) Monica Shah et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Individual Burden of Psoriasis (I-BOP): Building and Validation of a New Scoring Tool for Patients with Psoriasis

(2020) Khaled Ezzedine et al.   Clinical Cosmetic and Investigational Dermatology

Spotlight on Topical Long-Term Management of Plaque Psoriasis

(2020) Jose Manuel Carrascosa et al.   Clinical Cosmetic and Investigational Dermatology

Increased prevalence of family history of Alzheimer's disease in hidradenitis suppurativa: Cross‐sectional analysis of 192 HS patients

(2020) Pelin Esme et al.   Dermatologic Therapy

Alleviating and exacerbating foods in hidradenitis suppurativa

(2020) Jennifer M. Fernandez et al.   Dermatologic Therapy

Association Between Psoriasis and Dementia: Current Evidence

(2020) Liu Liu et al.   Frontiers in Aging Neuroscience

Gut–Brain–Skin Axis in Psoriasis: A Review

(2020) Guang Chen et al.   Dermatology and Therapy

Assessment of the Effect of Metabolic Syndrome on the Autophagy Marker LC3 in Psoriasis Vulgaris Patients: A Cross-Sectional Study

(2020) Essam A Nada et al.   Clinical Cosmetic and Investigational Dermatology

Association Between Psoriasis and Dementia: A Population-Based Case–Control Study

(2019) Ching-Chun Lin et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Neurological Disorders are Associated with Bullous Pemphigoid

(2019) E. Papakonstantinou et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

A Quarter Century of APOE and Alzheimer’s Disease: Progress to Date and the Path Forward

(2019) Michaël E. Belloy et al.   NEURON

Demographics and Autoantibody Profiles of Pemphigoid Patients with Underlying Neurologic Diseases

(2019) Kelly N. Messingham et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Psoriasis and Risk of Mental Disorders in Denmark

(2019) Michelle Z. Leisner et al.   JAMA Dermatology

Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin

(2019) S. Can Akerman et al.   JOURNAL OF ALZHEIMERS DISEASE

A New Discovery of MicroRNA-455-3p in Alzheimer’s Disease

(2019) Subodh Kumar et al.   JOURNAL OF ALZHEIMERS DISEASE

Inverse association for diagnosis of Alzheimer's disease subsequent to both melanoma and non-melanoma skin cancers in a large, urban, single-centre, Midwestern US patient population

(2018) E. Ibler et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

IL-17A and IL-23: plausible risk factors to induce age-associated inflammation in Alzheimer’s disease

(2018) Vahid Mohammadi Shahrokhi et al.   IMMUNOLOGICAL INVESTIGATIONS

Psoriasis is not associated with cognition, brain imaging markers and risk of dementia: the Rotterdam Study

(2018) Elena Pezzolo et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The amyloid precursor protein (APP) processing as a biological link between Alzheimer’s disease and cancer

(2018) Fernando Galvão et al.   AGEING RESEARCH REVIEWS

Analysis of Hidradenitis Suppurativa-Linked Mutations in Four genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages

(2018) Airong Li et al.   HUMAN MOLECULAR GENETICS

Analysis of Brain Donors’ Demographic and Medical Characteristics to Facilitate the Construction of a Human Brain Bank in China

(2018) Hanlin Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Association of Psoriasis With Inflammatory Bowel Disease

(2018) Yun Fu et al.   JAMA Dermatology

BP180 Autoantibodies Target Different Epitopes in Multiple Sclerosis or Alzheimer’s Disease than in Bullous Pemphigoid

(2018) Jussi Tuusa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Increased Levels of the Bullous Pemphigoid BP180 Autoantibody Are Associated with More Severe Dementia in Alzheimer’s Disease

(2017) Nina Kokkonen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Risk of Alzheimer's disease is not increased among patients with hidradenitis suppurativa: A retrospective population-based cohort analysis

(2017) Amit Garg et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Prevalence of chronic hepatitis B and C in psoriasis patients: A cross-sectional study in a large US population

(2017) Kelsey A. Orrell et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Non-melanoma skin cancer and risk of Alzheimer’s disease and all-cause dementia

(2017) Sigrun A. J. Schmidt et al.   PLoS One

A multi-hit hypothesis of bullous pemphigoid and associated neurological disease: IsHLA-DQB1*03:01, a potential link between immune privileged antigen exposure and epitope spreading?

(2017) K. T. Amber et al.   HLA

Cognitive Impairment in Patients with Psoriasis: A Cross-Sectional Study Using the Montreal Cognitive Assessment

(2016) Emine Colgecen et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Parkinson disease and multiple sclerosis are not associated with autoantibodies against structural proteins of the dermal-epidermal junction

(2016) A. Recke et al.   BRITISH JOURNAL OF DERMATOLOGY

Targeting Tumor Necrosis Factor Alpha for Alzheimer’s Disease

(2016) Boris Decourt et al.   Current Alzheimer Research

The Genetics of Hidradenitis Suppurativa

(2016) John R. Ingram   DERMATOLOGIC CLINICS

Bullous Pemphigoid, Neurodegenerative Disease, and Hippocampal BP180 Expression: A Retrospective Postmortem Neuropathologic Study

(2016) Benjamin J. Barrick et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Autoantibodies to Collagen XVII Are Present in Parkinson’s Disease and Localize to Tyrosine-Hydroxylase Positive Neurons

(2016) Kelly A.N. Messingham et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Bullous pemphigoid and its association with neurological diseases: a systematic review and meta-analysis

(2016) Y.C. Lai et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

(2016) Jennifer S. Yokoyama et al.   JAMA Neurology

Psychiatric and neurological disorders are associated with bullous pemphigoid – a nationwide Finnish Care Register study

(2016) Anna-Kaisa Försti et al.   Scientific Reports

One gene but different proteins and diseases: the complexity of dystonin and bullous pemphigoid antigen 1

(2015) Kseniia Künzli et al.   EXPERIMENTAL DERMATOLOGY

BRCA1 and p53 Tumor Suppressor Molecules in Alzheimer’s Disease

(2015) Atsuko Nakanishi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Mild Cognitive Impairment in Patients with Moderate to Severe Chronic Plaque Psoriasis

(2014) Paolo Gisondi et al.   DERMATOLOGY

Apolipoprotein E Gene Polymorphism and Serum Lipid Profile in Saudi Patients with Psoriasis

(2014) Fahad Al Harthi et al.   DISEASE MARKERS

A novel NCSTN mutation alone may be insufficient for the development of familial hidradenitis suppurativa

(2014) Yukiko Nomura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

A population-based study of the association between bullous pemphigoid and neurologic disorders

(2014) Katherine E. Brick et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Ustekinumab improves nail disease in patients with moderate-to-severe psoriasis: results from PHOENIX 1

(2013) P. Rich et al.   BRITISH JOURNAL OF DERMATOLOGY

Collagen XVII: A Shared Antigen in Neurodermatological Interactions?

(2013) Allan Seppänen   Clinical & Developmental Immunology

Lifestyle change and the prevention of cognitive decline and dementia

(2013) Martin Lövdén et al.   CURRENT OPINION IN PSYCHIATRY

UV Radiation and the Skin

(2013) John D'Orazio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phenotypic Heterogeneity in Hidradenitis Suppurativa (Acne Inversa): Classification Is an Essential Step Toward Personalized Therapy

(2013) John R. Ingram et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nonmelanoma skin cancer is associated with reduced Alzheimer disease risk

(2013) R. S. White et al.   NEUROLOGY

Presenilins and  -Secretase: Structure, Function, and Role in Alzheimer Disease

(2013) B. De Strooper et al.   Cold Spring Harbor Perspectives in Medicine

Apolipoprotein E Gene Polymorphism in Psoriasis: A Meta-analysis

(2012) Yi Han et al.   ARCHIVES OF MEDICAL RESEARCH

Absence of pathogenic γ-secretase mutations in a South Wales cohort of familial and sporadic hidradenitis suppurativa (acne inversa)

(2012) J.R. Ingram et al.   BRITISH JOURNAL OF DERMATOLOGY

Mutations in the γ-Secretase Genes NCSTN , PSENEN , and PSEN1 Underlie Rare Forms of Hidradenitis Suppurativa (Acne Inversa)

(2012) Andrew E. Pink et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of Three Hidradenitis Suppurativa Phenotypes: Latent Class Analysis of a Cross-Sectional Study

(2012) Florence Canoui-Poitrine et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Pemphigoid diseases

(2012) Enno Schmidt et al.   LANCET

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline

(2012) Johannes vom Berg et al.   NATURE MEDICINE

Association of Skin with the Pathogenesis and Treatment of Neurodegenerative Amyloidosis

(2012) Audra L. Clos et al.   Frontiers in Neurology

Comorbidity profiles among patients with bullous pemphigoid: a nationwide population-based study

(2011) Y.J. Chen et al.   BRITISH JOURNAL OF DERMATOLOGY

The Association of Bullous Pemphigoid With Cerebrovascular Disease and Dementia

(2010) Kathy Taghipour et al.   ARCHIVES OF DERMATOLOGY

What Can Be Inferred from the Interruption of the Semagacestat Trial for Treatment of Alzheimer's Disease?

(2010) Jeffrey Cummings   BIOLOGICAL PSYCHIATRY

Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K.

(2010) K Abuabara et al.   BRITISH JOURNAL OF DERMATOLOGY

Socioeconomic status and non-melanoma skin cancer: A nationwide cohort study of incidence and survival in Denmark

(2010) M. Steding-Jessen et al.   Cancer Epidemiology

REVIEW: γ-Secretase Inhibitors for the Treatment of Alzheimer's Disease: The Current State

(2010) Francesco Panza et al.   CNS Neuroscience & Therapeutics

Amyloid in skin and brain: What′s the link?

(2010) Stephan Schreml et al.   EXPERIMENTAL DERMATOLOGY

Sera of Elderly Bullous Pemphigoid Patients with Associated Neurological Diseases Recognize Bullous Pemphigoid Antigens in the Human Brain

(2010) Jinbo Chen et al.   GERONTOLOGY

Risk Factors for Bullous Pemphigoid in the Elderly: A Prospective Case–Control Study

(2010) Sylvie Bastuji-Garin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Relationship between Neurological Disease and Bullous Pemphigoid: A Population-Based Case–Control Study

(2010) Sinéad M. Langan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease

(2010) Suk Ling Ma et al.   NEUROBIOLOGY OF AGING

Apolipoprotein ε4 allele is associated with psoriasis severity

(2009) Pablo Coto-Segura et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Induction of Terminal Differentiation in Melanoma Cells on Downregulation of β-Amyloid Precursor Protein

(2009) Michelle G. Botelho et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cancer linked to Alzheimer disease but not vascular dementia

(2009) C. M. Roe et al.   NEUROLOGY

Amyloidosis and Neurodegenerative Diseases: Current Treatments and New Pharmacological Options

(2009) Jean-Paul Tillement et al.   PHARMACOLOGY