BRCA1 and p53 Tumor Suppressor Molecules in Alzheimer’s Disease

Limiting the power of p53 through the ubiquitin proteasome pathway

(2014) Vinod Pant et al.   GENES & DEVELOPMENT

Phytoestrogens and cognitive function: a review

(2014) Mira Soni et al.   MATURITAS

Baicalin attenuates Alzheimer-like pathological changes and memory deficits induced by amyloid β1–42 protein

(2014) Chong Chen et al.   METABOLIC BRAIN DISEASE

DNA Damage and Its Links to Neurodegeneration

(2014) Ram Madabhushi et al.   NEURON

p53-Dependent and Cell Specific Epigenetic Regulation of the Polo-like kinases under Oxidative Stress

(2014) Alejandra Ward et al.   PLoS One

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

(2014) Sara M. Hancock et al.   Frontiers in Aging Neuroscience

p53-dependent Fas expression is critical for Ginsenoside Rh2 triggered caspase-8 activation in HeLa cells

(2014) Xiao-Xi Guo et al.   Protein & Cell

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Chromatin modifications and DNA repair: beyond double-strand breaks

(2014) Nealia C. M. House et al.   Frontiers in Genetics

Thymoquinone protects cultured rat primary neurons against amyloid β-induced neurotoxicity

(2013) A.H. Alhebshi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypoxia and hypoxia mimetic cooperate to counteract tumor cell resistance to glucose starvation preferentially in tumor cells with mutant p53

(2013) Valery A. Chavez-Perez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: Implications for synaptic dysfunction and neuronal damage

(2013) P. Hemachandra Reddy   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nucleic acid oxidation: an early feature of Alzheimer's disease

(2013) Melissa A. Bradley-Whitman et al.   JOURNAL OF NEUROCHEMISTRY

BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis

(2013) Krishna K. Singh et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

A possible cause of Alzheimer’s dementia – Industrial soy foods

(2013) D. Roccisano et al.   MEDICAL HYPOTHESES

The DNA damage response during mitosis

(2013) Anne Margriet Heijink et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Suppressive effects of an ethanol extract of Gleditsia sinensis thorns on human SNU-5 gastric cancer cells

(2013) SE-JUNG LEE et al.   ONCOLOGY REPORTS

Knockdown of Pokemon Protein Expression Inhibits Hepatocellular Carcinoma Cell Proliferation by Suppression of AKT Activity

(2013) Xiaosan Zhu et al.   ONCOLOGY RESEARCH

Cycle Checkpoint Abnormalities during Dementia: A Plausible Association with the Loss of Protection against Oxidative Stress in Alzheimer’s Disease

(2013) Pavel Katsel et al.   PLoS One

Helicase-Like Transcription Factor (Hltf) Regulates G2/M Transition, Wt1/Gata4/Hif-1a Cardiac Transcription Networks, and Collagen Biogenesis

(2013) Rebecca A. Helmer et al.   PLoS One

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons

(2013) E. Keimpema et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone lysine trimethylation or acetylation can be modulated by phytoestrogen, estrogen or anti-HDAC in breast cancer cell lines

(2013) Aslihan Dagdemir et al.   Epigenomics

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

p53 at the crossroads between cancer and neurodegeneration

(2012) Cristina Lanni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress

(2012) Andleeb Khan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer’s disease patients

(2012) Noemí Esteras et al.   NEUROBIOLOGY OF AGING

Ginsennoside Rd Attenuates Cognitive Dysfunction in a Rat Model of Alzheimer’s Disease

(2012) Juanfang Liu et al.   NEUROCHEMICAL RESEARCH

Effects of ginsenoside Rg1 or 17β-estradiol on a cognitively impaired, ovariectomized rat model of Alzheimer’s disease

(2012) X. Zhang et al.   NEUROSCIENCE

Can Soy Phytoestrogens Decrease DNA Methylation in BRCA1 and BRCA2 Oncosuppressor Genes in Breast Cancer?

(2012) Rémy Bosviel et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Inhibitory Effect of Ethanol Extract ofMagnolia officinalison Memory Impairment and Amyloidogenesis in a Transgenic Mouse Model of Alzheimer's Disease via Regulating β-Secretase Activity

(2012) Young-Jung Lee et al.   PHYTOTHERAPY RESEARCH

A Novel Volume-Age-KPS (VAK) Glioblastoma Classification Identifies a Prognostic Cognate microRNA-Gene Signature

(2012) Pascal O. Zinn et al.   PLoS One

Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2

(2012) Milena Wiech et al.   PLoS One

G1/S Cell Cycle Checkpoint Defect in Lymphocytes from Patients with Alzheimer's Disease

(2012) Misun Song et al.   Psychiatry Investigation

Telomere shortening reduces Alzheimer’s disease amyloid pathology in mice

(2011) Harshvardhan Rolyan et al.   BRAIN

Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1

(2011) Sharon B Cantor et al.   Future Oncology

Clinical amyloid imaging in Alzheimer's disease

(2011) Karl Herholz et al.   LANCET NEUROLOGY

Niacin requirements for genomic stability

(2011) James B. Kirkland   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Neurohepatic toxicity of subacute manganese chloride exposure and potential chemoprotective effects of lycopene

(2011) Mohamed A. Lebda et al.   NEUROTOXICOLOGY

Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells

(2011) H. Konishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA repair deficiency in neurodegeneration

(2011) Dennis Kjølhede Jeppesen et al.   PROGRESS IN NEUROBIOLOGY

An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells

(2011) Irina Neganova et al.   STEM CELLS

DNA methylation and soy phytoestrogens: quantitative study in DU-145 and PC-3 human prostate cancer cell lines

(2011) Mawussi Adjakly et al.   Epigenomics

Baicalin inhibits PDGF-BB-stimulated vascular smooth muscle cell proliferation through suppressing PDGFRβ-ERK signaling and increase in p27 accumulation and prevents injury-induced neointimal hyperplasia

(2010) Li-Hua Dong et al.   CELL RESEARCH

Targeting Hypoxic Cells through the DNA Damage Response

(2010) M. Olcina et al.   CLINICAL CANCER RESEARCH

Hispidulin Potently Inhibits Human Glioblastoma Multiforme Cells through Activation of AMP-Activated Protein Kinase (AMPK)

(2010) Ying-Chao Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Differential expression of the klf6 tumor suppressor gene upon cell damaging treatments in cancer cells

(2010) Ricardo C. Gehrau et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Gleditsia sinensis thorn extract inhibits human colon cancer cells: the role of ERK1/2, G2/M-phase cell cycle arrest and p53 expression

(2010) Se-Jung Lee et al.   PHYTOTHERAPY RESEARCH

Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells

(2010) Chu Peng Hoi et al.   PHYTOTHERAPY RESEARCH

A Common Biological Mechanism in Cancer and Alzheimers Disease?

(2009) M. Behrens et al.   Current Alzheimer Research

Chinese herb related molecules of cancer-cell-apoptosis: a minireview of progress between Kanglaite injection and related genes

(2008) Yun Lu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Transcriptional role of p53 in interferon-mediated antiviral immunity

(2008) César Muñoz-Fontela et al.   JOURNAL OF EXPERIMENTAL MEDICINE