Journal
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
Volume 13, Issue -, Pages 325-+Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/CCID.S249776
Keywords
disease burden; psoriasis; quality of life; questionnaire; standardized method
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Funding
- Laboratoire Pharmaceutique Lilly France
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Background: Psoriasis impacts independently of its severity on patients' lifestyle and quality of life (QoL). Aim: To build a tool for assessing the patient-reported psoriasis burden. Methods: An expert group created a questionnaire using a standardized methodology building questionnaires assessing quality of life issues. The questionnaire was translated from French into a cultural and linguistically validated US English version. Results: A conceptual questionnaire of 54 questions was created. The confirmatory analyses resulted in a 10-feature questionnaire divided into 4 internally consistent domains with a Cronbach's alpha coefficient of 0.9. It was reproducible and highly reliable. It correlated well with the Dermatology Life Quality Index (DLQI), Perceived Stress Scale (PSS), and SF-12 mental and SF12 physical scores. Conclusion: This tool allows for the first time to assess the burden of psoriasis patients. Its use may allow improving medical and nonmedical patient care, thus improving their daily life.
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