Tumor Necrosis Factor (TNF) blocking agents are associated with lower risk for Alzheimer’s disease in patients with rheumatoid arthritis and psoriasis

TREM2 Attenuates Aβ1-42-Mediated Neuroinflammation in BV-2 Cells by Downregulating TLR Signaling

(2019) Huiping Long et al.   NEUROCHEMICAL RESEARCH

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

The polymorphism rs6918289 located in the downstream region of the TREM2 gene is associated with TNF-α levels and IMT-F

(2018) Vesna Gorenjak et al.   Scientific Reports

Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease

(2018) Inga Peter et al.   JAMA Neurology

TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease

(2018) Paramita Chakrabarty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Diagnosis and Management of Rheumatoid Arthritis

(2018) Daniel Aletaha et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Microglia in Alzheimer’s disease

(2017) David V. Hansen et al.   JOURNAL OF CELL BIOLOGY

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy

(2017) Shane M. Bemiller et al.   Molecular Neurodegeneration

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Female sex, early-onset hypertension, and risk of dementia

(2017) Paola Gilsanz et al.   NEUROLOGY

Therapeutic benefits of phosphodiesterase 4B inhibition after traumatic brain injury

(2017) Nicole M. Wilson et al.   PLoS One

TREM2, Microglia, and Neurodegenerative Diseases

(2017) Felix L. Yeh et al.   TRENDS IN MOLECULAR MEDICINE

Drugs for Autoimmune Inflammatory Diseases: From Small Molecule Compounds to Anti-TNF Biologics

(2017) Ping Li et al.   Frontiers in Pharmacology

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

Treatment for Rheumatoid Arthritis and Risk of Alzheimer’s Disease: A Nested Case-Control Analysis

(2016) Richard C. Chou et al.   CNS DRUGS

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice

(2016) Teng Jiang et al.   NEUROPHARMACOLOGY

Twelve-Year Retention Rate of First-Line Tumor Necrosis Factor Inhibitors in Rheumatoid Arthritis: Real-Life Data From a Local Registry

(2016) Ennio Giulio Favalli et al.   ARTHRITIS CARE & RESEARCH

Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective

(2015) Matthew Baumgart et al.   Alzheimers & Dementia

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Do glia drive synaptic and cognitive impairment in disease?

(2015) Won-Suk Chung et al.   NATURE NEUROSCIENCE

Etanercept in Alzheimer disease: A randomized, placebo-controlled, double-blind, phase 2 trial

(2015) J. Butchart et al.   NEUROLOGY

TNF and its receptors in the CNS: The essential, the desirable and the deleterious effects

(2015) L. Probert   NEUROSCIENCE

Tumor necrosis factor inhibitors: clinical utility in autoimmune diseases

(2015) Maria A.V. Willrich et al.   Translational Research

Body mass index and the risk of rheumatoid arthritis: a systematic review and dose-response meta-analysis

(2015) Baodong Qin et al.   ARTHRITIS RESEARCH & THERAPY

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alcohol Consumption and Risk of Incident Rheumatoid Arthritis in Women: A Prospective Study

(2014) Bing Lu et al.   Arthritis & Rheumatology

Using aggregated, de-identified electronic health record data for multivariate pharmacosurveillance: A case study of azathioprine

(2013) Vishal N. Patel et al.   JOURNAL OF BIOMEDICAL INFORMATICS

The impact of alcohol on Alzheimer's disease: A systematic review

(2012) Anna K. Piazza-Gardner et al.   AGING & MENTAL HEALTH

Patient characteristics associated with venous thromboembolic events: a cohort study using pooled electronic health record data

(2012) David C Kaelber et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Long term alcohol intake and risk of rheumatoid arthritis in women: a population based cohort study

(2012) D. Di Giuseppe et al.   BMJ-British Medical Journal

Normalized names for clinical drugs: RxNorm at 6 years

(2011) Stuart J Nelson et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Nonsteroidal Anti-Inflammatory Drugs Increase TNF Production in Rheumatoid Synovial Membrane Cultures and Whole Blood

(2010) T. H. Page et al.   JOURNAL OF IMMUNOLOGY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies

(2009) D Sugiyama et al.   ANNALS OF THE RHEUMATIC DISEASES

Meta-Analysis of Alzheimer's Disease Risk with Obesity, Diabetes, and Related Disorders

(2009) Louis A. Profenno et al.   BIOLOGICAL PSYCHIATRY

Protective effects of NSAIDs on the development of Alzheimer disease

(2008) Steven C. Vlad et al.   NEUROLOGY