Interaction Between Commensal Bacteria, Immune Response and the Intestinal Barrier in Inflammatory Bowel Disease

Autoimmune susceptibility gene PTPN2 is required for clearance of adherent-invasive Escherichia coli by integrating bacterial uptake and lysosomal defence

(2021) Marianne Rebecca Spalinger et al.   GUT

The effects of diet and gut microbiota on the regulation of intestinal mucin glycosylation

(2021) Dingwu Qu et al.   CARBOHYDRATE POLYMERS

Butyrate and the Fine-Tuning of Colonic Homeostasis: Implication for Inflammatory Bowel Diseases

(2021) Naschla Gasaly et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

AHR in the intestinal microenvironment: safeguarding barrier function

(2021) Brigitta Stockinger et al.   Nature Reviews Gastroenterology & Hepatology

The role of oral bacteria in inflammatory bowel disease

(2021) Emily Read et al.   Nature Reviews Gastroenterology & Hepatology

Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells

(2021) Louise Dupraz et al.   Cell Reports

Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis

(2020) Wei-Qi He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The microbiome and inflammatory bowel disease

(2020) Kerri L. Glassner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

(2020) Aonghus Lavelle et al.   Nature Reviews Gastroenterology & Hepatology

Growth effects of N-acylethanolamines on gut bacteria reflect altered bacterial abundances in inflammatory bowel disease

(2020) Nadine Fornelos et al.   Nature Microbiology

Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin

(2020) Ruth X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Paneth Cell: The Curator and Defender of the Immature Small Intestine

(2020) Shiloh R. Lueschow et al.   Frontiers in Immunology

Interactions of commensal and pathogenic microorganisms with the mucus layer in the colon

(2020) Rui Cai et al.   Gut Microbes

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis

(2020) Sho Kitamoto et al.   CELL

Intestinal epithelial glycosylation in homeostasis and gut microbiota interactions in IBD

(2020) Matthew R. Kudelka et al.   Nature Reviews Gastroenterology & Hepatology

Review article: how the intestinal microbiota may reflect disease activity and influence therapeutic outcome in inflammatory bowel disease

(2020) Clara Caenepeel et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

High-throughput sequencing provides insights into oral microbiota dysbiosis in association with inflammatory bowel disease

(2020) Ying Qi et al.   GENOMICS

Gain-of-function of ion channel TRPV1 exacerbates experimental colitis by promoting dendritic cell activation

(2020) Lina Duo et al.   Molecular Therapy-Nucleic Acids

Changes in dietary fiber intake in mice reveal associations between colonic mucin O-glycosylation and specific gut bacteria

(2020) Hasinika K. A. H. Gamage et al.   Gut Microbes

Gut Microbiota and Immune System Interactions

(2020) Ji Youn Yoo et al.   Microorganisms

Bacterial O-GlcNAcase genes abundance decreases in ulcerative colitis patients and its administration ameliorates colitis in mice

(2020) Xiaolong He et al.   GUT

The intestinal barrier, an arbitrator turned provocateur in IBD

(2020) Saurabh Mehandru et al.   Nature Reviews Gastroenterology & Hepatology

Pathophysiology of Inflammatory Bowel Diseases

(2020) John T. Chang   NEW ENGLAND JOURNAL OF MEDICINE

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice

(2019) Graham J. Britton et al.   IMMUNITY

Not by (Good) Microbes Alone: Towards Immunocommensal Therapies

(2019) Chung-Yin Leung et al.   TRENDS IN MICROBIOLOGY

Host immunoglobulin G selectively identifies pathobionts in pediatric inflammatory bowel diseases

(2019) Heather Armstrong et al.   Microbiome

Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation

(2019) Sebastian Zundler et al.   NATURE IMMUNOLOGY

Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis

(2019) Jin Imai et al.   Mucosal Immunology

Enterotoxigenic Clostridium perfringens Infection as an Adverse Event After Faecal Microbiota Transplantation in Two Patients With Ulcerative Colitis and Recurrent Clostridium difficile Infection: A Neglected Agent in Donor Screening

(2019) Masoumeh Azimirad et al.   Journal of Crohns & Colitis

Implications of the Westernized Diet in the Onset and Progression of IBD

(2019) Fernando Rizzello et al.   Nutrients

New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD

(2019) Anaïs Larabi et al.   Autophagy

Perspectives on Current and Novel Treatments for Inflammatory Bowel Disease

(2019) Soo-Young Na et al.   Gut and Liver

Flavonoid VI-16 protects against DSS-induced colitis by inhibiting Txnip-dependent NLRP3 inflammasome activation in macrophages via reducing oxidative stress

(2019) Yue Zhao et al.   Mucosal Immunology

Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD

(2019) Yi Rang Na et al.   Nature Reviews Gastroenterology & Hepatology

Therapeutic Opportunities in Inflammatory Bowel Disease: Mechanistic Dissection of Host-Microbiome Relationships

(2019) Damian R. Plichta et al.   CELL

Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis

(2019) Yuli Lin et al.   Mucosal Immunology

Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome

(2019) Israr Khan et al.   Pathogens

Microbiota and mucosal defense in IBD: an update

(2019) Eduard F. Stange et al.   Expert Review of Gastroenterology & Hepatology

A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease

(2019) Qingdong Guan   Journal of Immunology Research

Preventive antibiotic treatment of calves: emergence of dysbiosis causing propagation of obese state‐associated and mobile multidrug resistance‐carrying bacteria

(2019) Dorota A. Dobrzanska et al.   Microbial Biotechnology

Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease

(2019) June-Yong Lee et al.   CELL

Inflammation induced ER stress affects absorptive intestinal epithelial cells function and integrity

(2018) Sucheera Chotikatum et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Th17 plasticity and its relevance to inflammatory bowel disease

(2018) Aito Ueno et al.   JOURNAL OF AUTOIMMUNITY

GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3

(2018) Ye Zhao et al.   Mucosal Immunology

Proteus spp. as Putative Gastrointestinal Pathogens

(2018) Amy L. Hamilton et al.   CLINICAL MICROBIOLOGY REVIEWS

IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria

(2018) Akira Nakajima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont

(2018) Mo Xu et al.   NATURE

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

(2018) Hazel Tye et al.   Nature Communications

Association between Cigarette Smoking Status and Composition of Gut Microbiota: Population-Based Cross-Sectional Study

(2018) Su Hwan Lee et al.   Journal of Clinical Medicine

Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function

(2018) Shiyang Li et al.   IMMUNITY

Antibiotics Potentiate Adherent-Invasive E. coli Infection and Expansion

(2018) Alexander M Oberc et al.   INFLAMMATORY BOWEL DISEASES

The Protective Role of Bacteroides fragilis in a Murine Model of Colitis-Associated Colorectal Cancer

(2018) Yun Kyung Lee et al.   mSphere

Oxygen as a driver of gut dysbiosis

(2017) Fabian Rivera-Chávez et al.   FREE RADICAL BIOLOGY AND MEDICINE

Probiotics in Inflammatory Bowel Disease

(2017) Bincy P. Abraham et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Adherent-invasiveEscherichia coliin inflammatory bowel disease

(2017) Carolina Palmela et al.   GUT

Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

(2017) Siew C Ng et al.   LANCET

Microbial Ecology along the Gastrointestinal Tract

(2017) Ethan T. Hillman et al.   MICROBES AND ENVIRONMENTS

Salt-responsive gut commensal modulates TH17 axis and disease

(2017) Nicola Wilck et al.   NATURE

Interactions of Intestinal Bacteria with Components of the Intestinal Mucus

(2017) Jean-Félix Sicard et al.   Frontiers in Cellular and Infection Microbiology

Butyrate-producing bacteria supplemented in vitro to Crohn’s disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

(2017) Annelies Geirnaert et al.   Scientific Reports

Breathless in the Gut: Implications of Luminal O 2 for Microbial Pathogenicity

(2016) Caleb J. Kelly et al.   Cell Host & Microbe

Gut Microbial Metabolites Fuel Host Antibody Responses

(2016) Myunghoo Kim et al.   Cell Host & Microbe

Formation of propionate and butyrate by the human colonic microbiota

(2016) Petra Louis et al.   ENVIRONMENTAL MICROBIOLOGY

Antibiotics as deep modulators of gut microbiota: between good and evil

(2016) Gianluca Ianiro et al.   GUT

Fungal microbiota dysbiosis in IBD

(2016) Harry Sokol et al.   GUT

Promotion of Intestinal Epithelial Cell Turnover by Commensal Bacteria: Role of Short-Chain Fatty Acids

(2016) Jung-ha Park et al.   PLoS One

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

(2016) H. Chu et al.   SCIENCE

Advances in nutritional therapy in inflammatory bowel diseases: Review

(2016) Andrzej Wędrychowicz   WORLD JOURNAL OF GASTROENTEROLOGY

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

(2016) Audrey Rivière et al.   Frontiers in Microbiology

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut

(2015) Liesbeth Allais et al.   ENVIRONMENTAL MICROBIOLOGY

Assessment of mucosal healing in inflammatory bowel disease: review

(2015) Parambir S. Dulai et al.   GASTROINTESTINAL ENDOSCOPY

Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence

(2015) Monika Schaubeck et al.   GUT

Saccharomyces cerevisiae CNCM I-3856 Prevents Colitis Induced by AIEC Bacteria in the Transgenic Mouse Model Mimicking Crohnʼs Disease

(2015) Adeline Sivignon et al.   INFLAMMATORY BOWEL DISEASES

Emerging functions of serum amyloid A in inflammation

(2015) Richard D. Ye et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Prevalence of Mycobacterium avium subsp. paratuberculosis and Escherichia coli in blood samples from patients with inflammatory bowel disease

(2015) Nair Nazareth et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

(2015) Laurence Macia et al.   Nature Communications

Meta-analysis of gut barrier dysfunction in patients with acute pancreatitis

(2014) L. M. Wu et al.   BRITISH JOURNAL OF SURGERY

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

The gut microbiota and inflammatory bowel disease

(2014) Katsuyoshi Matsuoka et al.   Seminars in Immunopathology

Inflammatory bowel disease: Pathogenesis

(2014) Yi-Zhen Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches

(2013) Anna Ermund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

Lyn activity protects mice from DSS colitis and regulates the production of IL-22 from innate lymphoid cells

(2013) J L Bishop et al.   Mucosal Immunology

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+Th17 cells

(2012) Margherita Coccia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IBD—what role do Proteobacteria play?

(2012) Indrani Mukhopadhya et al.   Nature Reviews Gastroenterology & Hepatology

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Gut barrier dysfunction in the ApcMin/+ mouse model of colon cancer cachexia

(2011) Melissa J. Puppa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease

(2011) J. L. Benjamin et al.   GUT

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

GCMS-based metabolomic study in mice with colitis induced by dextran sulfate sodium

(2011) Yuuki Shiomi et al.   INFLAMMATORY BOWEL DISEASES

Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

(2010) Chin Wen Png et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohnʼs disease

(2010) S. C. Ng et al.   INFLAMMATORY BOWEL DISEASES

Highlighting new phylogenetic specificities of Crohnʼs disease microbiota

(2010) S. Mondot et al.   INFLAMMATORY BOWEL DISEASES

The role of infection in the aetiology of inflammatory bowel disease

(2010) Richard Hansen et al.   JOURNAL OF GASTROENTEROLOGY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Epithelial crosstalk at the microbiota-mucosal interface

(2010) J. M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

(2010) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine

(2009) Petra Louis et al.   FEMS MICROBIOLOGY LETTERS

Therapeutic correction of bacterial dysbiosis discovered by molecular techniques

(2008) R. B. Sartor   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring Microbial Diversity and Taxonomy Using SSU rRNA Hypervariable Tag Sequencing

(2008) Susan M. Huse et al.   PLoS Genetics