The role of oral bacteria in inflammatory bowel disease

Pathway paradigms revealed from the genetics of inflammatory bowel disease

(2020) Daniel B. Graham et al.   NATURE

Microbiome in Colorectal Cancer: How to Get from Meta-omics to Mechanism?

(2020) Dominik Ternes et al.   TRENDS IN MICROBIOLOGY

Abundance and diversity of resistomes differ between healthy human oral cavities and gut

(2020) Victoria R. Carr et al.   Nature Communications

Impact of commonly used drugs on the composition and metabolic function of the gut microbiota

(2020) Arnau Vich Vila et al.   Nature Communications

Commensal Bacteroidetes protect against Klebsiella pneumoniae colonization and transmission through IL-36 signalling

(2020) Richard P. Sequeira et al.   Nature Microbiology

Defining the oral microbiome by whole-genome sequencing and resistome analysis: the complexity of the healthy picture

(2020) Elisabetta Caselli et al.   BMC MICROBIOLOGY

Fusobacterium nucleatum exacerbates colitis by damaging epithelial barrier and inducing aberrant inflammation

(2020) Hua Liu et al.   Journal of Digestive Diseases

The role of the microbiota in periodontal disease

(2020) Mike A. Curtis et al.   PERIODONTOLOGY 2000

Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease

(2020) F. J. Ryan et al.   Nature Communications

Periodontitis and inflammatory bowel disease: a meta-analysis

(2020) Yang-yang She et al.   BMC Oral Health

Spatial Ecology of the Human Tongue Dorsum Microbiome

(2020) Steven A. Wilbert et al.   Cell Reports

Current Sampling Methods for Gut Microbiota: A Call for More Precise Devices

(2020) Qiang Tang et al.   Frontiers in Cellular and Infection Microbiology

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis

(2020) Sho Kitamoto et al.   CELL

Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

(2020) Lishay Parhi et al.   Nature Communications

A predictive index for health status using species-level gut microbiome profiling

(2020) Vinod K. Gupta et al.   Nature Communications

Identification of Specific Oral and Gut Pathogens in Full Thickness Colon of Colitis Patients: Implications for Colon Motility

(2019) Vasudevan Dinakaran et al.   Frontiers in Microbiology

Oral bacteria colonize and compete with gut microbiota in gnotobiotic mice

(2019) Bolei Li et al.   International Journal of Oral Science

Modelling microbiome recovery after antibiotics using a stability landscape framework

(2019) Liam P. Shaw et al.   ISME Journal

Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β‐catenin modulator Annexin A1

(2019) Mara Roxana Rubinstein et al.   EMBO REPORTS

Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease

(2019) Matthias Friedrich et al.   IMMUNITY

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

Klebsiella and Providencia emerge as lone survivors following long-term starvation of oral microbiota

(2019) Jonathon L. Baker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive transmission of microbes along the gastrointestinal tract

(2019) Thomas SB Schmidt et al.   eLife

Biogeography of the Oral Microbiome: The Site-Specialist Hypothesis

(2019) Jessica L. Mark Welch et al.   Annual Review of Microbiology

Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation

(2019) Triantafyllos Chavakis et al.   NATURE IMMUNOLOGY

Periodontitis is associated with an increased risk for proximal colorectal neoplasms

(2019) Gun Woo Kim et al.   Scientific Reports

Quantitative microbiome profiling disentangles inflammation- and bile duct obstruction-associated microbiota alterations across PSC/IBD diagnoses

(2019) Sara Vieira-Silva et al.   Nature Microbiology

The Landscape of Genetic Content in the Gut and Oral Human Microbiome

(2019) Braden T. Tierney et al.   Cell Host & Microbe

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

(2019) Sunny H. Wong et al.   Nature Reviews Gastroenterology & Hepatology

Risk of bacteremia in hospitalised patients with inflammatory bowel disease: a 9-year cohort study

(2019) Idan Goren et al.   United European Gastroenterology Journal

The cytokine network involved in the host immune response to periodontitis

(2019) Weiyi Pan et al.   International Journal of Oral Science

Gut Microbiota Composition Before and After Use of Proton Pump Inhibitors

(2018) Mariko Hojo et al.   DIGESTIVE DISEASES AND SCIENCES

Patients with colorectal cancer have identical strains ofFusobacterium nucleatumin their colorectal cancer and oral cavity

(2018) Yasuhiko Komiya et al.   GUT

Dysbiotic Biofilms Deregulate the Periodontal Inflammatory Response

(2018) E.R. Herrero et al.   JOURNAL OF DENTAL RESEARCH

Oral microbiome alterations of healthy volunteers with proton pump inhibitor

(2018) Tsuyoshi Mishiro et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Tissue-Specific Immunity at the Oral Mucosal Barrier

(2018) Niki M. Moutsopoulos et al.   TRENDS IN IMMUNOLOGY

Indoleamine 2,3-dioxygenase expression regulates the survival and proliferation of Fusobacterium nucleatum in THP-1-derived macrophages

(2018) Ying Xue et al.   Cell Death & Disease

Molecular epidemiology and comparative genomics of Campylobacter concisus strains from saliva, faeces and gut mucosal biopsies in inflammatory bowel disease

(2018) Karina Frahm Kirk et al.   Scientific Reports

Dysbiosis of the salivary microbiota in pediatric-onset primary sclerosing cholangitis and its potential as a biomarker

(2018) Kentaro Iwasawa et al.   Scientific Reports

Dysbiosis and Ecotypes of the Salivary Microbiome Associated With Inflammatory Bowel Diseases and the Assistance in Diagnosis of Diseases Using Oral Bacterial Profiles

(2018) Zhe Xun et al.   Frontiers in Microbiology

Dynamics of metatranscription in the inflammatory bowel disease gut microbiome

(2018) Melanie Schirmer et al.   Nature Microbiology

Extensive impact of non-antibiotic drugs on human gut bacteria

(2018) Lisa Maier et al.   NATURE

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course

(2018) Melanie Schirmer et al.   Cell Host & Microbe

Fusobacterium nucleatum — symbiont, opportunist and oncobacterium

(2018) Caitlin A. Brennan et al.   NATURE REVIEWS MICROBIOLOGY

The oral microbiota: dynamic communities and host interactions

(2018) Richard J. Lamont et al.   NATURE REVIEWS MICROBIOLOGY

A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans

(2018) Nicolas Dutzan et al.   Science Translational Medicine

The oral microbiota in colorectal cancer is distinctive and predictive

(2017) Burkhardt Flemer et al.   GUT

A microbial signature for Crohn's disease

(2017) Victoria Pascal et al.   GUT

Primary sclerosing cholangitis – a comprehensive review

(2017) Tom H. Karlsen et al.   JOURNAL OF HEPATOLOGY

Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

(2017) Siew C Ng et al.   LANCET

Quantitative microbiome profiling links gut community variation to microbial load

(2017) Doris Vandeputte et al.   NATURE

Strains, functions and dynamics in the expanded Human Microbiome Project

(2017) Jason Lloyd-Price et al.   NATURE

Gut microbiota and IBD: causation or correlation?

(2017) Josephine Ni et al.   Nature Reviews Gastroenterology & Hepatology

GAS6 is a key homeostatic immunological regulator of host–commensal interactions in the oral mucosa

(2017) Maria Nassar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation

(2017) Koji Atarashi et al.   SCIENCE

Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

(2017) Lukas Bajer et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Campylobacter concisus Genomospecies 2 Is Better Adapted to the Human Gastrointestinal Tract as Compared with Campylobacter concisus Genomospecies 1

(2017) Yiming Wang et al.   Frontiers in Physiology

Dynamics of the human gut microbiome in inflammatory bowel disease

(2017) Jonas Halfvarson et al.   Nature Microbiology

Nitric oxide as a potential biomarker in inflammatory bowel disease

(2017) Nesina Avdagić et al.   Bosnian Journal of Basic Medical Sciences

Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc

(2016) Jawad Abed et al.   Cell Host & Microbe

Fungal microbiota dysbiosis in IBD

(2016) Harry Sokol et al.   GUT

Gut microbiome and liver diseases

(2016) Herbert Tilg et al.   GUT

Characterization of the human immune cell network at the gingival barrier

(2016) N Dutzan et al.   Mucosal Immunology

Fusobacterium nucleatum-Induced Impairment of Autophagic Flux Enhances the Expression of Proinflammatory Cytokines via ROS in Caco-2 Cells

(2016) Bin Tang et al.   PLoS One

Biogeography of a human oral microbiome at the micron scale

(2016) Jessica L. Mark Welch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Examination of the effects of Campylobacter concisus zonula occludens toxin on intestinal epithelial cells and macrophages

(2016) Vikneswari Mahendran et al.   Gut Pathogens

Optimized cultivation of Campylobacter concisus from gut mucosal biopsies in inflammatory bowel disease

(2016) Karina Frahm Kirk et al.   Gut Pathogens

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells

(2016) Nandan P. Deshpande et al.   Scientific Reports

Genome analysis of Campylobacter concisus strains from patients with inflammatory bowel disease and gastroenteritis provides new insights into pathogenicity

(2016) Heung Kit Leslie Chung et al.   Scientific Reports

Role of type 2 immunity in intestinal inflammation

(2015) Giorgos Bamias et al.   CURRENT OPINION IN GASTROENTEROLOGY

Proton pump inhibitors affect the gut microbiome

(2015) Floris Imhann et al.   GUT

Proton pump inhibitors alter the composition of the gut microbiota

(2015) Matthew A Jackson et al.   GUT

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

Alterations of the Subgingival Microbiota in Pediatric Crohnʼs Disease Studied Longitudinally in Discovery and Validation Cohorts

(2015) Judith Kelsen et al.   INFLAMMATORY BOWEL DISEASES

Dental Caries and Periodontal Disease in Children and Adolescents with Inflammatory Bowel Disease

(2015) Vassiliki Koutsochristou et al.   INFLAMMATORY BOWEL DISEASES

Delineation of genetic relatedness and population structure of oral and enteric Campylobacter concisus strains by analysis of housekeeping genes

(2015) Vikneswari Mahendran et al.   MICROBIOLOGY-SGM

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Distinctive inflammatory bowel disease phenotype in primary sclerosing cholangitis

(2015) A Boudewijn de Vries   WORLD JOURNAL OF GASTROENTEROLOGY

Same Exposure but Two Radically Different Responses to Antibiotics: Resilience of the Salivary Microbiome versus Long-Term Microbial Shifts in Feces

(2015) E. Zaura et al.   mBio

Distinct but Spatially Overlapping Intestinal Niches for Vancomycin-Resistant Enterococcus faecium and Carbapenem-Resistant Klebsiella pneumoniae

(2015) Silvia Caballero et al.   PLoS Pathogens

Functional biomarkers for chronic periodontitis and insights into the roles of Prevotella nigrescens and Fusobacterium nucleatum; a metatranscriptome analysis

(2015) Szymon P Szafrański et al.   npj Biofilms and Microbiomes

Bacteria from Diverse Habitats Colonize and Compete in the Mouse Gut

(2014) Henning Seedorf et al.   CELL

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

(2014) Dirk Gevers et al.   Cell Host & Microbe

Oral cavity contains distinct niches with dynamic microbial communities

(2014) Xin Xu et al.   ENVIRONMENTAL MICROBIOLOGY

Klebsiella pneumoniae Translocates across the Intestinal Epithelium via Rho GTPase- and Phosphatidylinositol 3-Kinase/Akt-Dependent Cell Invasion

(2014) Chun-Ru Hsu et al.   INFECTION AND IMMUNITY

Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis

(2014) Ana E Duran-Pinedo et al.   ISME Journal

Metagenomic Analysis of Nitrate-Reducing Bacteria in the Oral Cavity: Implications for Nitric Oxide Homeostasis

(2014) Embriette R. Hyde et al.   PLoS One

Dissemination of Periodontal Pathogens in the Bloodstream after Periodontal Procedures: A Systematic Review

(2014) Anna Carolina Ratto Tempestini Horliana et al.   PLoS One

PNAS Plus: From the Cover: Oligotyping analysis of the human oral microbiome

(2014) A. M. Eren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal barrier in inflammatory bowel disease

(2014) Lena Antoni   WORLD JOURNAL OF GASTROENTEROLOGY

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Dysbiosis of Salivary Microbiota in Inflammatory Bowel Disease and Its Association With Oral Immunological Biomarkers

(2013) H. S. Said et al.   DNA RESEARCH

Diversity of human small intestinalStreptococcusandVeillonellapopulations

(2013) Bartholomeus van den Bogert et al.   FEMS MICROBIOLOGY ECOLOGY

Periodontitis and Gingivitis in Inflammatory Bowel Disease

(2013) Stephan R. Vavricka et al.   INFLAMMATORY BOWEL DISEASES

Colorectal cancer in inflammatory bowel disease: Results of the 3rd ECCO pathogenesis scientific workshop (I)

(2013) Shaji Sebastian et al.   Journal of Crohns & Colitis

Aggravation of inflammatory bowel diseases by oral streptococci

(2013) A Kojima et al.   ORAL DISEASES

Host-Derived Nitrate Boosts Growth of E. coli in the Inflamed Gut

(2013) S. E. Winter et al.   SCIENCE

Drugs that inhibit gastric acid secretion may alter the course of inflammatory bowel disease

(2012) P. Juillerat et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Intestinal colonization resistance

(2012) Trevor D. Lawley et al.   IMMUNOLOGY

The role of neutrophils during intestinal inflammation

(2012) B M Fournier et al.   Mucosal Immunology

The role of the gut microbiota in nutrition and health

(2012) Harry J. Flint et al.   Nature Reviews Gastroenterology & Hepatology

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

Investigation of the Enteric Pathogenic Potential of Oral Campylobacter concisus Strains Isolated from Patients with Inflammatory Bowel Disease

(2012) Yazan Ismail et al.   PLoS One

Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples

(2012) Nicola Segata et al.   GENOME BIOLOGY

Fusobacterium nucleatum Infection of Colonic Cells Stimulates MUC2 Mucin and Tumor Necrosis Factor Alpha

(2011) Poonam Dharmani et al.   INFECTION AND IMMUNITY

Invasive potential of gut mucosa-derived fusobacterium nucleatum positively correlates with IBD status of the host

(2011) Jaclyn Strauss et al.   INFLAMMATORY BOWEL DISEASES

Comparison of the fecal microbiota profiles between ulcerative colitis and Crohn’s disease using terminal restriction fragment length polymorphism analysis

(2011) Akira Andoh et al.   JOURNAL OF GASTROENTEROLOGY

The association between inflammatory bowel disease and periodontitis among Jordanians: a case-control study

(2011) R. A. Habashneh et al.   JOURNAL OF PERIODONTAL RESEARCH

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

The Pathogenic Potential of Campylobacter concisus Strains Associated with Chronic Intestinal Diseases

(2011) Nadeem O. Kaakoush et al.   PLoS One

Klebsiella pneumoniaeincreases the risk of inflammation and colitis in a murine model of intestinal bowel disease

(2011) In-Ah Lee et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

The Role of Oral Hygiene in Inflammatory Bowel Disease

(2010) Shashideep Singhal et al.   DIGESTIVE DISEASES AND SCIENCES

Host Attachment, Invasion, and Stimulation of Proinflammatory Cytokines byCampylobacter concisusand Other Non–Campylobacter jejuni CampylobacterSpecies

(2010) Si Ming Man et al.   JOURNAL OF INFECTIOUS DISEASES

Campylobacter concisus and other Campylobacter species in children with newly diagnosed Crohnʼs disease

(2009) Si Ming Man et al.   INFLAMMATORY BOWEL DISEASES